임상 ; 한국 산모와 신생아의 비타민 D 영양 상태 조사

나보미 ( Bo Mi Na ),노소정 ( So Jung No ),김미정 ( Mi Jung Kim ),한헌석 ( Heon Seok Han ),정은환 ( Eun Hwan Jeong ),한영희 ( Young Hee Han ),현태선 ( Tai Sun Hyeun ) 대한주산의학회 2007 Perinatology Vol.18 No.4

목적: 한국 산모와 신생아의 비타민 D 영양 상태를 조사하여 비타민 D 부족의 발생률과 그 정도를 알아보고, 이에 영향을 미치는 요인들을 분석하였다. 방법: 2004년 8월부터 2005년 7월까지 충북대학교병원 산부인과에서 출산한 총 181쌍의 산모와 건강한 만삭아를 대상으로 하였다. 분만시 산모와 제대혈의 혈청 25-OH 비타민 D3(25OHD3), alkaline phosphatase (AP), 칼슘(Ca), 인(P), 부갑상선 호르몬(PTH) 농도를 측정하였으며, 모성 면담과 설문 조사를 통하여 자외선 조사량과 비타민 D의 일일 평균 섭취량을 구하여 비교분석하였다. 결과: 1) 산모와 신생아의 혈청 25OHD3 농도는 각각 23.4±9.9과 16.9±7.5 ng/mL이었다. 2) 8 %의 산모와 22%의 신생아가 비타민 D 결핍 상태였으며, 70%의 산모와 신생아에서 부족 상태를 보였다. 3) 산모와 신생아의 25OHD3 농도는 강한 양의 상관관계를 보였다(r=0.7270, p<0.0001). 4) 산모와 신생아의 비타민 D 영양 상태에 가장 큰 영향을 미치는 요인은 출산 계절로 하절기(6~11월)에 높았다. 5) 다중회귀분석 결과, 산모에서는 출산 계절과 분만 방식이, 신생아에서는 산모의 25OHD3와 분만 방식이 비타민 D 농도와 연관성이 있는 것으로 나타났다. 결론: 한국 산모와 신생아는 비타민 D 영양 결핍이나 부족 상태에 있는 경우가 많았으며, 출산 계절이 비타민 D 영양 상태에 가장 큰 영향을 미치는 것으로 나타났다. Objective: To evaluate the vitamin D nutritional status and its influencing factors in Korean mothers and their newborn infants. Methods: Maternal (n=181) and cord blood (n=180) serum concentrations of vitamin D (25OHD3), calcium, inorganic phosphorus, alkaline phosphatase, intact parathyroid hormone were measured at the time of delivery. We defined vitamin D deficient, insufficient, and sufficient as 25OHD3 <11, 11~30, and >30 ng/mL, respectively. Using questionnaires, average duration of sun-light exposure (minutes/day) and dietary intake of vitamin D (μg/day) were obtained. Results: 1) The mean 25OHD3 level in mothers was 23.4±9.9 (range 4~71.6) ng/mL, and in newborns, 16.9±7.5 (range 0.9~53.6) ng/mL. 2) 8.3% of mothers and 22.2 % of newborns were vitamin D deficient, and 70% of both mothers and newborns were insufficient. 3) Maternal 25OHD3 showed a strong positive correlation with cord blood 25OHD3 (r=0.727, p<0.001). 4) The most significant risk factor for low 25OHD3 levels was the season of birth (June through November) in both mothers and newborns. 5) In multiple logistic regression analysis, the season of birth and the mode of delivery remained significant for maternal vitamin D status, whereas maternal 25OHD3 and the mode of delivery remained significant for neonatal vitamin D status. Conclusion: In conclusion, vitamin D deficiency or insufficiency was relatively common in Korean mothers and their newborn infants, and the most significant risk factor for low vitamin D status was the season of birth.

외음부의 기저세포암

김보영 ( Bo Young Kim ),황선정 ( Sun Jung Hwang ),박병준 ( Byung Joon Park ),이은실 ( Eun Sil Lee ),한호섭 ( Ho Suap Han ),김용욱 ( Yong Wook Kim ),김태응 ( Tae Eung Kim ),노덕영 ( Duck Yeong Ro ),이안희 ( An Hi Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.9

Basal cell carcinoma (BCC) is the most common human malignant neoplasm, accounting for 75% of all non-melanoma skin cancer. The incidence of BCC is strongly correlated with sun exposure as well as older age. Therefore, the vast majority of BCCs is observed in elderly patients on the sun-exposed skin of the head and neck with a frequency of more than 80%. BCC is very rare on sun-protected skin such as the perianal and genital regions and other etiologic factors must be considered in these cases. Although the pathogenesis of vulvar BCC is unclear, early diagnosis is very important. Because BCC in these areas sometimes seems innocuous, it is recommended that a biopsy of all suspect lesions be performed. We report a woman with BCC of the vulva treated with wide local resection and reviews the literatures on this subject.

제주에서 플러그묘의 육묘일수가 양배추 생육 및 수량에 미치는 영향

고순보,박용봉,김기택 濟州大學校 亞熱帶農業硏究所 1998 亞熱帶農業硏究 Vol.15 No.-

양배추 플러그 육묘시 적정 육묘일수를 구명하기 위하여 시험을 실시한 결과는 다음과 같다. 1. 플러그묘가 육묘일수에 관계없이 노지육묘묘에 비해 정식시 뿌리의 손상이 적어 활착율이 높았다. 2. 정식초기에는 대묘를 정식한 노지육묘묘의 초장이 길었으나 정식 후 시간이 경과 할수록 플러그묘의 초장이 길어졌다. 3. 2월 수확시 상품수량이 가장 많았으며 25, 30일 플러그묘인 경우 구중은 차이를 보이고 있지 않지만 열구율이 적어 상품 수량이 많았으며 노지 육묘묘에 비해 각각 29.1%, 35.6%의 증수효과를 나타냈다. This experiment was carried out to determine the optimum age of transplant and plugseedlings on plant growth and marketable yields of cabbage in Cheju Island. Plugseedlings raised cabbages taking root rates were compared with outdoor seedling rates after planting. Shortly after planting, the plant height of large outdoor seedlings increased. However, with the passage of time after planting, the plant height of plugseedlings was greater than that of outdoor seedlings. Marketable yields were greatest at February harvest. There was no difference between 25 and 30 days old plugseedlings for head weight and head cracking rates decreased. The yields of 25 and 30 days old plugseedlings increased by 29.1% and 35.6%, respectively, compared to outdoor seedlings.

자바 기술을 이용한 선형수열 나눔 소수(prime number)의 밀도 분석 컴포넌트 개발

옥보명,황철선 영산대학교 2003 영산논총 Vol.12 No.-

J. C. Lagarias showed that the set of primes dividing certain second-order linear recurrences has positive density. He stated three cases of density for the set of primes that dividing the terms of the recurrences. The aim of this paper is to develope a very large integer analysis system for a density of the set of primes dividing linear recurrences by Java technology. Also, the system can visualize the density of the float type of some particular linear sequences.

복지권으로서 교육권 보장을 위한 『장애인 등에 대한 특수교육법』

황정보,이선재,안병주,강경희,김청아 국립특수교육원 2007 특수교육연구 Vol.14 No.2

결핍에서 오는 필요의 개념은 장애인에게 복지권으로서 교육받을 권리를 가장 잘 말해주고 있다. 장애인은 신체적·인지적 손상으로 발생하는 기본적인 생존적 필요의 충족뿐만 아니라 동시에 교육기회 균등이나 개인차의 고려 등을 통해 무지로부터 벗어날 수 있는 보편적 필요가 충족되어야 함을 논의하였다. 장애인들에게 이러한 결핍에 따른 필요를 충족시켜 줄 이론적 근거가 롤즈(J. Rawls)의 정의론이라 할 수 있다. 정의론의 '차등의 원칙'에 따르면, 교육에 있어 비장애인과 장애인 중 먼저 최소 수혜자인 장애인의 교육복지를 우선하여 극대화할 필요성을 제시함으로써, 그들의 교육권 보장을 위한 이론적 근거에 대한 정당화를 논의하였다. 기존의 특수교육진흥법은 '국가가 교육할 권리'를 가지는 국가 주도적 교육이었다면, 「장애인 등에 대한 특수교육법」 제정은 수년간 장애인의 교육권 확보를 위해 애쓴 장애인 교육 주체들이 노력 끝에 '교육받을 권리'를 찾게 된 의미 있는 결실로 평가되어 진다. The concept of need which comes from lack represents well the right to education as welfare rights to individuals with disabilities. It is necessary to meet the universal need of individuals with disabilities such as an equal opportunity for education and the consideration for individual difference as well as their substantial need. The rationale which may satisfy the need associated with the lack can be J. Rawls's a Theory of Justice. The difference principle by Rawls presents the need of the educational welfare of individuals with disabilities(the least advantaged) to take precedence over that of the non-disabled and be maximized, it is considered that he created the rationale that makes secure their right to education. While established Special Education Promotion Law was national-driven education that state had to the education right, the enactment of 'the Special Education Law for the Individuals with Disabilities, etc.' can be a significant fruit which takes back 'the right to education by citizens' by the educational subjects of the individuals with disability who have taken pains to secure their right to education for years.

청소년의 사회인구학적 변인과 체육활동 욕구와의 관계

이보선 龍仁大學校 體育科學硏究所 1998 體育科學硏究論叢 Vol.8 No.1

The purpose of this study is to examine the relationships between background of socio-demography of youth and physical activity of the needs. Data collected through a questionnaire designed for this study consist of fixed-alternative choice response to items constructed to represent the operational definition for each variable. The test items used in measuring sport-related needs in the previous studies were classified, using Cronbach's α analysis. Seven factors and 42 items were selected for the present study. The subjects of the study were 534(M;288, F;246) of youth in Yong-in City. After responses with a low relibility were excluded using a response set method, the data from 534 individuals were analyzed. Analysis of the data was done by analysis of Frequency, t-test, oneway ANOVA, using the statistical package. Based upon the results of the study, the following conclusions appear warranted: First, the background of youth were differentiated by gender. Second, the background of youth were differentiated by education. Third, the background of youth were differentiated by academic career of parents. Fourth, the background of youth were differentiated by income.

서울시내 고등학교 위탁급식의 급식비와 투자비의 실태 및 위탁업체의 기대수준 비교 분석

양일선,배환미,김현아,신서영,조미나,박수연,차진아,이보숙 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.5

The purposes of this study were to a) find out the operational characteristics of the contract-managed highschool foodservice in Seoul, b) investigate the expected level of meal-price and facilities investment cost perceived by contract-managed highschool foodservice managers c) compare the present level and expected level of meal-price and facilities investment cost. From October 12 to November 13 in 2001, the questionnaires were mailed to 249 high schools which was managed by contract foodservice company with respondent rate 40.2%. Data were analyzed using SPSS Win(10.0) for descriptive analysis and one group paired t-test. The results of this study were as follows ; 1. The student enrollment of highschools run by contract-managed foodservice was 1,243 with 72.6% participation rate of school lunch program. The average meal-price was 2,138 won. The average annual period of school foodservice operation was 156.78 days per year. The average contracting period was about 3 years. 2. The average cost concerned in the facilities investment amounts 169,578,180 won at the initial investment and 25,204,092 won at the repairs and maintenance cost in the course of operation. 3. The present level of meal-price and facilities investment cost were respectively 2,136won/meal and 171,157,336.72 won. And expected level.of meal-price and amount of facilities investment cost were 2,418.75 won and 121,353,215.19 won. Comparing the present level with expected level of the meal-price and facilities investment cost, expected level of meal-price was significantly higher than the present level of meal-price(p<.001) and expected level of facilities investment cost was significantly lower than present level of facilities investment cost(p<.001).

이탈리아어 절(節) 연구 : 구문 강독 난해성 원인 분석

崔普善 대구효성가톨릭대학교 외국어문학연구소 1994 語文學硏究 Vol.7 No.-

여자 체조 이단평행봉 연기에 대한 분석

이보선,박순호,이필영,최정현 龍仁大學校 體育科學硏究所 2001 體育科學硏究論叢 Vol.11 No.1

The purpose of the study is to help Korean women gymnasts get better grades in the international sports arena by understanding the world trends in this field based on the analyses of performances in the parallel bars, the weakest event among the four Korean women's gymnastic events. Value, connection value by which bonus points can be obtained, and start value were analyzed, excluding demerit marks in general performances, impressions, and art. The results of the study are as follows. In the analysis of value, the top four athletes implemented more parts than the average level while the four Korean athletes achieved less than the average level. According to the analysis of value parts D and E, the top four athletes received an average of 0.675 bonus points while the Koreans got 0.15, showing a great difference among them. The analysis of connection value by which bonus points can be obtained also showed stark contrast between the top four athletes and the Koreans marking bonus points of 0.50 and 0.075, respectively. The average start value of the top four athletes was 9.95, 0.925 higher than that of the Korean athletes of 9.025, which can be considered as a big difference. It is suggested that Korean athletes should focus on conducting high level of value parts and connection value to make greater achievements in the international sports arena, considering general demerit points were not included in this study. They are also needed to be confident in order to act to the best of their abilities.

벼꽃으로부터 두 개의 calmodulin cDNA 유전자의 분리 및 특성 연구

고보경,고명수,김유정,정일선,최영주 신라대학교 자연과학연구소 2005 自然科學論文集 Vol.14 No.-

Ca^(2+)은 신호전달과정에서 중요한 작용을 하는데 CaM은 이러한 Ca^(2+)이은의 modulator로서 중요한 작용을 하는 것으로 알러져 있다. 벼꽃의 cDNA library로부터 rice genomic DNA(RCaM-2)를 probe로 사용하여 30여개의 Positive clones을 얻어 이 중 두 개의 벼꽃 calmodulin CDNA clone을 분리하였다. RFCaMs CDNA clone의 총염기수는 RFCaM-3은 831p, RFCaM-4는 751bp이고 open reading frame은 각각 149개의 아미노산으로 구성되어 있다. RFCaM-3 과 RFCaM-4의아미노산은 동일하지만 nucleotide 순서는 상당한 차이를 나타내고 있다. RFCaMs CDNA clone의 open reading flame은 protein serine/threonine kinase에 보존되어 있는 catalytic domain을 가지고 있다 RfCaM-3은 5'-untranslated region은 105bp, 3'-untranslated region은 270bp이고 RfCaM-4는 5'-untranslated region은 78bp, 3'-untranslatedregion은 283bp이다. RFCaMs는 Arabidopsis와 70%, potato와는 92%, carrot과는 98%의 유사성을 보였다. Genomic southern blot분석에 의하면 벼의 clamodulin 유전자들이 7-8개의 multigene family로 존재하는 것으로 나타났다. Two different calmodulin (CaM) cDNAs (RFCaM-3 and RFCaM-4) were isolated from a rice flower cDNA library by screening with a rice genomic probe (RCaM-2). Both cDNAs are 90% sequence homologous inside the coding region but are highly divergent outside this region. The polypeptides encoded by RFCaM-3 and RFCaM-4 show identical sequence homology. Comparison of the deduced amino acid sequence of the RFCaMs cDNA clone have identity to Arabidopsis (70%), potato (92%), carrot (98%), and barley and soybean (98%). Southern analysis revealed that both cDNAs are encoded by different genes. Four intense and a few weaker bands were observed in the restriction fragments. Most restriction fragments showed high intensity hybridization signals under stringent conditions, suggesting the presence of a small multigene family for CaM in the rice genome as in other plants.