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박빛나,조윤경 이화여자대학교 특수교육연구소 2012 특수교육 Vol.11 No.1
본 연구는 통합유아교육기관에 재원 중인 청각장애유아 부모와의 면담을 통해 청각장애유아의 통합 상황과 부모의 요구에 대해 알아봄으로써 청각장애유아의 효과적인 통합을 위한 구체적인 지원방안을 제시하고자 시행하였다. 수도권에 위치한 통합유아교육기관에 재원 중인 만 3-5세 청각장애유아의 어머니 6명을 대상으로 반구조화된 면담을 실시하였다. 연속적비교법을 이용하여 부호화한 후, 부호들 간의 연속적인 비교를 통해 범주와 주제를 형성하여 분석한 결과는 다음과 같다. 첫째, 청각장애유아의 통합유아교육기관 입소 과정은 법 제정으로 인해 비교적 용이하였고, 언어와 사회성 발달을 위해 통합유아교육기관을 선택하고 있었다. 둘째, 통합유아교육기관에서 청각장애유아는 입소 시 다양한 어려움을 겪었지만, 통합유아교육기관의 지원방법 및 내용에 따라 통합유아교육기관에 대한 부모의 만족도는 차이가 있었다. 셋째, 청각장애유아는 개별화교육 등 여러 지원을 받고 있었으나, 청각장애를 위한 전문적인 지원은 받지 못하고 있었다. 넷째, 청각장애유아의 부모는 통합유아교육기관에 대해 청각장애유아를 위한 전문적인 지원을 원하였고, 사회성 증진을 위한 또래와의 긍정적 관계 형성과 더불어서 청각장애유아의 재활을 위한 국가의 경제적 지원과 교육적 지원이 필요하다고 요구하였다. This study aims to investigate the inclusive early childhood education conditions of hearing-impaired children and the need of the children’s parents through face-to-face interview with the parents, and to suggest the support devices for effective inclusion of the hearing-impaired children into general education class. In this study, semi-structured interviews were conducted with six mothers of 3 to 5 year old hearing-impaired children who are attending inclusive early childhood educational settings located in Seoul. The result of this study is as follows. First, admission to inclusive early childhood educational settings was relatively easy because of the special education laws. Hearing-impaired children chose to attend inclusive educational settings for their social development. Second, the hearing-impaired children experienced various difficulties, parents showed the differences in education satisfaction according to the supporting methods and content of inclusive education. Third, the hearing-impaired children received the individualized education, etc., but not with professional support for their hearing impairment. Fourth, the parents of the hearing-impaired children asked for professional support for the children as well as reinforcing the children’s positive relation with their peers for social improvement. And they were asking for governmental financial and educational support for the children’s rehabilitation.
( Bit Na Rae Kim ),( Ja Young Kwon ),( Ye Jin Park ),( Myung Hwa Kang ),( Jong Rak Choi ),( Young Geun Kwon ),( Young Han Kim ),( Yong Won Park ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.8
Objective Nephrin is one of the slit membrane proteins of podocytes in the kidney. It is known that the nephrin is shed in the urine in nephropathy accompanying proteinuira. So the aim of this study was to evaluate the difference in the serum nephrin expression between normal and preeclamptic pregnancies. Methods A total of 20 pregnant women from May to September 2008 who received prenatal care and underwent delivery at our institute participated in the study. The preeclamptic group includes 13 women diagnosed as preeclampsia and a normal group of 7. Their serum were collected before delivery and analyzed by Western blotting for comparing serum nephrin expression. Results There was no difference in age, body weight of pregnant women, blood urea nitrogen, serum creatinine, urine creatinine level and gestational age between two groups. However, preeclampsia group had significantly higher systolic and diastolic blood pressure ( P<0.001), serum soluble fms-like tyrosine kinase-1 level ( P= 0.002), and lower birth weight ( P=0.011). In serum Western blot analysis, serum nephrin was detected in 10 of 13 in preeclampsia women (76.9%) but only in 2 of 7 (28.6%) in normal pregnancy women showing statistically significant difference ( P=0.032). Conclusion A higher prevalence of nephrin expression in the maternal serum was found in the preeclampsia when compared to the normal pregnancy.
Expression of Pseudorabies Virus Glycoproteins gB, gC and gD using Insect Expression System
( Bit Na Rae Yun ),( Won Seok Gwak ),( Ji Hoon Lee ),( Soo Dong Woo ) 한국잠사학회 2017 International Journal of Industrial Entomology Vol.35 No.2
Porcine pseudorabies virus (PRV) causes the Aujeszky's disease (AD) which is economically important disease in the swine industry worldwide. Killed or live vaccines have been used to control this disease, but their efficacy and side effects remain problems to be solved. To solve these problems, in this study, production of recombinant PRV glycoprotein gB, gC and gD was investigated in insect expression system. Glycoprotein gB, gC and gD are regarded as the major immunogenic antigens in PRV. Abundant production and immunogenicity of glycoprotein gB, gC and gD were confirmed by SDS-PAGE and Western blot analysis, respectively. Optimal infection dose and time were also determined for the production of each recombinant PRV glycoprotein. Confirmation of glycosylation of recombinant gB, gC and gD suggested their usefulness as antigens for the development of diagnosis kit or vaccines for Aujeszky’s disease. ⓒ 2017 The Korean Society of Sericultural Sciences Int. J. Indust. Entomol. 35(2), 118-122 (2017)