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      • KCI등재

        Valorization of rice bran: Modified supercritical CO2 extraction of bioactive compounds

        Oscar Benito-Román,Sandra Varona,María Teresa Sanz,Sagrario Beltrán 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-

        In this work, as afirst step in a comprehensive strategy for the valorization of rice bran, the extraction ofoil using supercritical CO2 and ethanol as cosolvent has been studied. The effect of extractiontemperature (40 and 60 C), pressure (30 and 40 MPa) and amount of ethanol used (0, 5 and 10%) has beenconsidered. The quality extracted oil has been evaluated in terms of antioxidant activity, fatty acid profileand bioactive compounds such as phenolics,flavonoids, g-oryzanols, and tocopherols content. Results revealed that, using neat CO2, the best oil in terms of antioxidant activity was obtained at 40 Cand 30 MPa. However, the addition of ethanol as modifier significantly increased the amount of bioactivemolecules extracted and hence the overall antioxidant activity of the oil, which was maximum at 40 MPaand 10% ethanol, regardless the temperature. The use of ethanol also affected the amount of fatty acidsand g-oryzanols extracted.

      • THE ROLE OF BRANDS IN ONLINE VS. OFFLINE CHANNELS

        Óscar González-Benito,Mercedes Martos-Partal,Sonia San Martín 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.7

        This article addresses the potential of reputable brands to overcome the lack of tangibility that characterizes the process of e-commerce. In a sequential argument, the authors propose that (1) the brand becomes more important in online than in offline channels, as a consequence of the intangibility or lack of physical contact in online purchasing processes; (2) the limitations associated with the need for touch and the lack of access to the physical product during the buying process does not have equal importance across all product categories; and (3) the role of the brand in online channels thus is more relevant if the product category is associated with a higher need for touch. To provide empirical evidence regarding the hypotheses, we performed an experiment that combined three treatments: (1) leader versus non-leader brand, (2) online versus offline channel, and (3) product category with higher versus lower need for touch. We show that the most recognized brands exert a positive effect on product evaluations, regardless of the technical characteristics and other objective product attributes. This advantage may be greater in online channels, though only for product categories for which the lack of physical contact with the product during the purchase process is an important limitation. In such cases, brand associations can compensate for intangibility during purchase.We also confirm that the product categories differ in their level of need for touch and the extent to which consumers desire physical contact with the product during the buying process. These results demonstrate that building strong brands is a key competitive advantage for manufacturers. Brand reputation becomes even more crucial when selling products in electronic channels, at least if the product itself entails a greater need for touch prior to purchase. For such products, strong brands can make up for the intangibility of e-commerce, so this effort represents a key competitive strategy in such channels. Moreover, leading brands can leverage their competitive advantage to enhance their performance in the increasingly prominent realm of e-commerce. E-retailers need to make careful decisions regarding the configuration of the assortment, taking into account the nature of the product category. They should strengthen their focus on developing highly recognizable brands, because the lack of physical contact is an important purchase inhibitor in this shopping channel. However, the brand criterion may be less important if the choice between online and offline shopping is not particularly affected by the opportunity to touch or feel the products.

      • THE ROLE OF BRANDS IN ONLINE VS. OFFLINE CHANNELS

        ?scar Gonz?lez-Benito,Mercedes Martos-Partal,Sonia San Mart?n 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.7

        This article addresses the potential of reputable brands to overcome the lack of tangibility that characterizes the process of e-commerce. In a sequential argument, the authors propose that (1) the brand becomes more important in online than in offline channels, as a consequence of the intangibility or lack of physical contact in online purchasing processes; (2) the limitations associated with the need for touch and the lack of access to the physical product during the buying process does not have equal importance across all product categories; and (3) the role of the brand in online channels thus is more relevant if the product category is associated with a higher need for touch. To provide empirical evidence regarding the hypotheses, we performed an experiment that combined three treatments: (1) leader versus non-leader brand, (2) online versus offline channel, and (3) product category with higher versus lower need for touch. We show that the most recognized brands exert a positive effect on product evaluations, regardless of the technical characteristics and other objective product attributes. This advantage may be greater in online channels, though only for product categories for which the lack of physical contact with the product during the purchase process is an important limitation. In such cases, brand associations can compensate for intangibility during purchase.We also confirm that the product categories differ in their level of need for touch and the extent to which consumers desire physical contact with the product during the buying process. These results demonstrate that building strong brands is a key competitive advantage for manufacturers. Brand reputation becomes even more crucial when selling products in electronic channels, at least if the product itself entails a greater need for touch prior to purchase. For such products, strong brands can make up for the intangibility of e-commerce, so this effort represents a key competitive strategy in such channels. Moreover, leading brands can leverage their competitive advantage to enhance their performance in the increasingly prominent realm of e-commerce. E-retailers need to make careful decisions regarding the configuration of the assortment, taking into account the nature of the product category. They should strengthen their focus on developing highly recognizable brands, because the lack of physical contact is an important purchase inhibitor in this shopping channel. However, the brand criterion may be less important if the choice between online and offline shopping is not particularly affected by the opportunity to touch or feel the products.

      • KCI등재
      • KCI등재

        Robotic single site radical hysterectomy plus pelvic lymphadenectomy in gynecological cancers

        Enrico Vizza,Benito Chiofalo,Giuseppe Cutillo,Emanuela Mancini,Ermelinda Baiocco,Ashanti Zampa,Arabella Bufalo,Giacomo Corrado 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.1

        Objective: To evaluate the feasibility and the safety of robotic single-site radical hysterectomy (RSSRH) plus pelvic lymphadenectomy (PL) in endometrial or cervical cancer. Methods: Patients with endometrial cancer (EC) International Federation of Gynecology and Obstetrics (FIGO) stage II, early cervical cancer (ECC) FIGO stage IB1 or locally advanced cervical cancer (LACC) FIGO stage IB2–IIB with clinical response ≥50% after neo-adjuvant chemotherapy (NACT) were enrolled in a prospective cohort trial. All cases were performed using the da Vinci Si Surgical Single Site System®. Results: Between April 2014 and November 2016, twenty patients were included in our pilot study. Three and 17 patients underwent type B1 or C1 RSSRH plus PL, respectively. The median age of patients was 46 years (range, 36–68 years) and the median body mass index was 23.5 kg/m2 (range, 19.1–36.3 kg/m2). The median total operative time was 190 minutes (range, 90–310 minutes). The median blood loss was 75 mL (range, 20–700 mL) and the median number of pelvic lymph nodes removed was 16 (range, 5–27). No laparoscopic/laparotomic conversions were reported and the median time to discharge was 6 days (range, 4–16 days). No intra-operative complications occurred while 4 (20%) post-operative complications were reported: one pelvic abscess, one lymphorrea, one bowel perforation, and one vaginal dehiscence. Conclusion: RSSRH plus PL is technically feasible in patients affected by gynecological cancer.

      • KCI등재

        질소시용수준이 수도 분얼경의 소유관속 발육에 미치는 영향

        Dong Jin Lee,Benito S. Vergara,Oscar B. Zamora,Ie Sung Shim,Bong Ku Kim,Je Cheon Chae 韓國作物學會 1994 Korean journal of crop science Vol.39 No.4

        본 실험은 질소시용 수준이 수도의 이삭줄기, 엽신 및 엽초의 소유관속 발육에 미치는 영향을 구명 하여 수량을 증대시킬 수 있는 방안을 모색하기 위하여 '89∼'90년에 국제벼연구소 (IRRI)에서 인도형인 IR 58과 일본형인 운봉 7을 공시하여 수행하였다. 1. 분얼경의 수수절간에 발달된 소유관속수는 질소시용 수준이 증가할수록 유의하게 증가되는 경향이었으며, 주간의 경우 질소 무시용구에 비하여 질소시용구에서 IR 58은 39% 및 운봉 7은 24% 증가하였다. 2. 주간 및 일찍 출현된 1, 2차 분얼경의 발육 순서로 소유관속수가 많이 발육되어 있었으며, 분얼경의 출현이 늦을수록 유관속의 발육이 저하 되었다. 3. 주간의 수수절간, 엽신 및 엽초의 소유관속발육은 질소 무비구 및 소비구에 비하여 질소 증시구에서 다소 증가하는 경향이었다. 4. 수수절간의 소유관속수는 이삭당 영화수 및 입중과 밀접한 정의 상관관계를 나타냈으며, 이는 줄기에 발달된 소유관속이 영화수의 분화와 깊은 연관성을 가지고 있으며, 발달된 유관속을 통해 양수분 전류가 원할히 이루어져서 결국 이삭당 입중도 증가되는 결과를 보였다. The experiments were conducted to evaluate the effect of nitrogen application on the development of small vascular bundle in the rice plants. Two cultivars, IR58, an indica type and Unbong 7, a japonica type were used in this study. The number of small vascular bundles in peduncle of different tillers was increased with the increase of nitrogen level. In the main culm, number of small vascular bundles at higher nitrogen level was increased by 39% in IR58 and 24% in Unbong 7 compared with nitrogen free plot. The main culm had more small vascular bundles in the peduncle and number of small vascular bundle was decreased with later tiller order and tiller development. The number and cross sectional area of small vascular bundles in flag leaf blade and sheath of main culm were increased with increasing levels of nitrogen. The number of small vascular bundles in peduncle was highly correlated with the number of spikelets and grain weight per panicle.

      • KCI등재

        Modeling Chagas Disease at Population Level to Explain Venezuela’s Real Data

        Gilberto Gonza´lez-Parra,Benito M. Chen-Charpentier,Moises Bermu´dez 질병관리본부 2015 Osong Public Health and Research Persptectives Vol.6 No.5

        Objectives: In this paper we present an age-structured epidemiological model for Chagas disease. This model includes the interactions between human and vector populations that transmit Chagas disease. Methods: The human population is divided into age groups since the proportion of infected individuals in this population changes with age as shown by real prevalence data. Moreover, the age-structured model allows more accurate information regarding the prevalence, which can help to design more specific control programs. We apply this proposed model to data from the country of Venezuela for two periods, 1961-1971, and 1961-1991 taking into account real demographic data for these periods. Results: Numerical computer simulations are presented to show the suitability of the age-structured model to explain the real data regarding prevalence of Chagas disease in each of the age groups. In addition, a numerical simulation varying the death rate of the vector is done to illustrate prevention and control strategies against Chagas disease. Conclusion: The proposed model can be used to determine the effect of control strategies in different age groups.

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