Dopa-Responsive Dystonia: A Male Patient Inherited a Novel GCH1 Deletion from an Asymptomatic Mother

Wendi Wang,Baozhong Xin,Heng Wang 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.2

Dopa-responsive dystonia (DRD) is a complex genetic disorder with either autosomal dominant or autosomal recessive inheritance,with autosomal dominant being more frequent. Autosomal dominant DRD is known to be caused by mutations in theGCH1 gene, with incomplete penetrance frequently reported, particularly in males. Here, we report a male patient with DRDcaused by exon 1 deletion in the GCH1 gene inherited from the asymptomatic mother. The patient had an atypical presentation,notably with no dystonia, and underwent extensive workup for a myriad of neuromuscular disorders before a low-dose L-dopatrial and confirmatory genetic testing were performed. Our experience with this family highlights an atypical presentation ofDRD and prompts us to consider the genetic complexity of DRD.

The Breed and Sex Effect on the Carcass Size Performance and Meat Quality of Yak in Different Muscles

Li Zhang,Baozhong Sun,Qun-li Yu,Qiumei Ji,Peng Xie,Haipeng Li,Li Wang,Yuchun Zhou,Yongpeng Li,Caixia Huang,Xuan Liu 한국축산식품학회 2016 한국축산식품학회지 Vol.36 No.2

The carcass size performances and the meat quality of Gannan and Sibu yak were determined using M. supraspinatus (SU), M. longissimus thoracis (LT) and M.quadriceps femoris (QF). It is found that Sibu yak had significantly higher carcass weight (CW) than Gannan yak with difference of nearly 40 kg, as well as significantly higher eye muscle area (EMA), carcass thorax depth (CTD), round perimeter (RP), etc. The carcass performances of steer yak were significantly higher than heifer yak except meat thickness at round (MTR) (p<0.05). The results show that both yak breed and gender had significant effects on carcass performances. It could be seen that the variation of carcass size performances from breeds is as large as from gender (50.22% and 46.25% of total variation, respectively) through principal component analysis (PCA). Sibu yak had significantly higher L*, b*, WBSF, cooking loss and Fat content, while Gannan yak had significantly higher a*, press loss, protein content and moisture (p<0.05). Yak gender and muscle had insignificant effects on meat colour and water holding capacity (p>0.05). The variation of meat quality of yak from breed is up to 59.46% of total variation according to PCA. It is shown that the difference between breeds, for Gannan yak and Sibu yak, plays an important role in carcass size performance and meat quality.

An effective method for directly extracting lithium from a-spodumene by activated roasting and sulfuric acid leaching

Yuqing Zhang,Baozhong Ma,Yingwei Lv,Chengyan Wang,Yongqiang Chen 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.122 No.-

The global trend toward electrification has encouraged lithium’s market position to grow prominently. Spodumene is the focus of lithium extraction owing to its abundant lithium resources. In this study, anovel lithium extraction method was proposed for a-spodumene by combining activated roasting andsulfuric acid leaching. First, the thermodynamics of the roasting process demonstrated that aspodumenewas converted into b-spodumene, which reacted with CaO to produce acid-solubleLiAlSiO4 and CaSiO3 concurrently. The addition of CaO reduced the melting temperature, which promotedthe structural transformation of b-spodumene and further acid leaching. Then, the influences of variousfactors on lithium extraction were investigated by a single-factor test. A lithium leaching yield of 96.18%was obtained under optimum conditions: 20% CaO, roasting temperature of 1200 C, holding time of1.5 h, H2SO4 concentration of 120 g/L, liquid–solid ratio of 7:1 mL/g, leaching temperature of 80 Cand leaching time of 1.5 h. Finally, Li entered into leach liquor by the action of sulfuric acid, and the maincomponents of the leach residue were silicate and calcium sulfate. Compared to the conventional acidapproach, this method has a higher lithium recovery and lower energy and acid consumption (decreaseby approximately 0.42 kg/ kg).

Extraction of valuable components from coal gangue through thermal activation and HNO3 leaching

Shuang Shao,Baozhong Ma,Chengyan Wang,Yongqiang Chen 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.113 No.-

Coal gangue has the dual attributes of hazard and resource. With the increasing awareness of resourcesconservation and ecological sustainability, the high-value utilization of coal gangue has attracted activeattention. In this research, thermal activation followed by HNO3 leaching were performed to extract valuablecomponents from coal gangue. Firstly, the activation behavior and phase transformation mechanismduring thermal activation were revealed through the Gibbs free energy calculation and experimentalresearch. After activation, inert kaolinite was converted to active metakaolinite. Subsequently, thepotential-pH diagrams analyses confirmed that the strategy of extracting Al, Ga, and Li into the leachliquor while precipitating Fe into the leach residue was feasible. Meanwhile, systematic leaching experimentsshowed that 95.2% of Al, 56.4% of Ga, and 80.5% of Li were extracted, while only 2.1% of Fe wasdissolved at the optimal conditions. The leaching behavior of each component agreed well with the thermodynamicanalysis. Finally, the raw ore, activated product, and leach residue were analyzed via a suiteof characterization techniques. In contrast to the raw ore and activated product, the leach residue hadlarge BET surface area and high available Si content, and was a promising Si fertilizer source. This studyprovides a useful reference for the high-value utilization of coal gangue.

Two Exploring Experiments on IMS Service Based on SIP AS

Kun Li,Baozhong Cheng,Xiaoyan Zhang,Youzheng Chen 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.4

Research on Fast Face RecognitionAlgorithm Based on Block CS-LBP and HIK Kernel Method

Shaoming Pan,Gongkun Luo,Baozhong Ke,Kejiang Li 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.12

With the development of artificial intelligence and pattern recognition technology, more and more research related to human face is constantly developing in all walks of life. At the present stage, the traditional face recognition algorithm based on LBP and SVM is not good, and the process of feature extraction and feature classification are deeply studied in this paper. For feature extraction, the authors put forward an improved CS-LBP texture feature; for feature classification, the author uses the histogram intersection (HIK) kernel function to classify the features which has high efficiency and good effect. Subsequently, experiments are carried out on the Yale data set and the ORL data set. Experimental results show that the proposed algorithm has a significant improvement on the face recognition effect of face direction change, and the illumination change is slightly improved. In the natural environment, most face recognition has the influence of human face direction and noise, and the effect of noise is a hot direction of face recognition research in the future.

The Breed and Sex Effect on the Carcass Size Performance and Meat Quality of Yak in Different Muscles

Zhang, Li,Sun, Baozhong,Yu, Qunli,Ji, Qiumei,Xie, Peng,Li, Haipeng,Wang, Li,Zhou, Yuchun,Li, Yongpeng,Huang, Caixia,Liu, Xuan Korean Society for Food Science of Animal Resource 2016 한국축산식품학회지 Vol.36 No.2

The carcass size performances and the meat quality of Gannan and Sibu yak were determined using M. supraspinatus (SU), M. longissimus thoracis (LT) and M.quadriceps femoris (QF). It is found that Sibu yak had significantly higher carcass weight (CW) than Gannan yak with difference of nearly 40 kg, as well as significantly higher eye muscle area (EMA), carcass thorax depth (CTD), round perimeter (RP), etc. The carcass performances of steer yak were significantly higher than heifer yak except meat thickness at round (MTR) (p<0.05). The results show that both yak breed and gender had significant effects on carcass performances. It could be seen that the variation of carcass size performances from breeds is as large as from gender (50.22% and 46.25% of total variation, respectively) through principal component analysis (PCA). Sibu yak had significantly higher L*, b*, WBSF, cooking loss and Fat content, while Gannan yak had significantly higher a*, press loss, protein content and moisture (p<0.05). Yak gender and muscle had insignificant effects on meat colour and water holding capacity (p>0.05). The variation of meat quality of yak from breed is up to 59.46% of total variation according to PCA. It is shown that the difference between breeds, for Gannan yak and Sibu yak, plays an important role in carcass size performance and meat quality.

Strengthening extraction of lithium and rubidium from activated α-spodumene concentrate via sodium carbonate roasting

Huidong Zhou,Yubo Liu,Baozhong Ma,Chengyan Wang,Yongqiang Chen 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.123 No.-

As a critical resource, lithium is necessary for the flourishing of clean energy as an upstream raw material. With the global popularity of lithium batteries and strict requirements for environmental protection, ashort, cost-effective lithium extraction process from a-spodumene was critical. In this paper, a novel processfor efficient and direct extraction of lithium from a-spodumene was proposed. The main contents ofthe process were sodium roasting, water quenching and strengthening leaching. Firstly, the thermodynamicbehavior of the roasting products was analyzed using Factsage 7.0 software. Subsequently, the factorsof lithium extraction were investigated by single-factor condition experiments. And the responsesurface methodology (RSM) was used to carry out the three-factor and three-level Box-Behnken experiments. The investigation revealed that a-spodumene reacted directly with Na2CO3 at high temperature toform Li2SiO3, NaAlSiO4, and Na2SiO3. The stable aluminosilicate structure in a-spodumene was destroyedby the combined effect of sodium roasting and water quenching, which played a significant role in therelease of lithium. In addition, the Na2CO3 dosage dominated the effect of lithium extraction, followedby roasting temperature and roasting time. Based on the model optimization results, the optimal roastingconditions were determined to be roasting at 1100 C for 30 min with the addition of 45% Na2CO3. Theextraction rates of Li and Rb were 95.9% and 90.3%, respectively, whereas those of Al was only 1.5%. This process provides a technological solution for the high-efficiency and synergistic extraction of valuableelements in a-spodumene.

Phase transformation and roasting kinetics of cobalt-rich copper sulfide ore in oxygen atmosphere assisted by sodium sulfate

Xiang Li,Yubo Liu,Weijiao Yang,Baozhong Ma,Yongqiang Chen,Chengyan Wang 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.116 No.-

The recovery rates of copper (99 %) and cobalt (93 %) could be significantly increased by adding sodiumsulfate in activated roasting of Cobalt-rich copper sulfide (CRCS). The mechanism and kinetic parametersof CRCS roasting with sodium sulfate addition were not clear. Thus, in this study, the thermal roastingkinetics of carrollite (the predominant cobalt occurrence mineral) in CRCS adding Na2SO4 with an airatmosphere was studied in detail by TG-DTG method. The apparent activation energy (E) and preexponentialfactor (A) were obtained via Flynn-Wall-Ozawa method (FWO) and Kissinger-Akahira-Sunose method (KAS) methods, where E values were 113.89 kJmol1 (KAS) and 120.87 kJmol1(FWO). The thermodynamic parameters of the roasting process were evaluated. The model function forthe carrollite reaction was determined via Malek analysis. The mechanism of sodium sulfate additionin CRCS roasting was studied. Results showed that the addition of sodium sulfate in activated roastingcan promote the transformation of carrollite mineral phase. The activation energy value of the oxidationprocess of carrollite decreases. From the kinetic point of view, the addition of sodium sulfate can promotethe activation roasting.

Trophic Effect of Bee Pollen on Small Intestine in Broiler Chickens

Heng Wang,Jue Wang,Shenghe Li,Qifa Wang,Baozhong Xin 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.2

In this study, the effects of bee pollen on the development of digestive organs were evaluated in broiler chick-ens. A total of 144 1-day-old AA broiler chickens were randomly and equally divided into two groups, assigned as the con-trol group and the pollen group, respectively. The control group was fed with a basic diet, while the pollen group was fedwith a basic diet supplemented with 1.5% bee pollen over a period of 6 weeks. At the end of each week, the digestive organswere obtained for comparison from 12 broilers randomly selected from each group. The results demonstrated that comparedto the control group, the small intestine villi from the duodenum, jejunum, and ileum were longer and thicker in the pollengroup. This difference was more significant during early development, especially through the first 2 weeks. Bee pollen in-creased the length of the villi by 37.1% and 29.4% in the duodenum, 28.1% and 33.7% in the jejunum, and 18.6% and 16.2%in the ileum in week 1 and 2, respectively. Furthermore, the small intestinal glands were developed at a higher density in thepollen group, and the depth of the glands was significantly increased by bee pollen in the first 2 weeks. These findings sug-gest that bee pollen could promote the early development of the digestive system and therefore is a potentially beneficial foodsupplement for certain conditions, such as short bowel syndrome.