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Anti-collapse performance analysis of unequal span steel–concrete composite substructures
Bao Meng,Liangde Li,Wei-hui Zhong,Zheng Tan,Yu-hui Zheng 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.39 No.4
In the study, three 1:3-scale unequal span steel–concrete composite substructures with top-seat angle and double web angle connection were designed and identified as specimens GTSDWA-0.6, GTSDWA-1.0, and GTSDWA-1.4. Pseudo-static tests and refined numerical model analysis were conducted to examine the anti-progressive collapse performance of a semi-rigid steel–concrete composite substructure. The results indicated that the failure modes of the three specimens revealed that the fracture occurred in the root of the long leg of the top/seat angle in tension at the connection. With increases in the span ratio of the left and right composite beams, the bearing capacities of the composite substructures decreased, and the corresponding displacement increased. With respect to GTSDWA-0.6 and GTSDWA-1.4, the resistance due to the short composite beam corresponded to 62% and 60%, respectively, and the total resistance provided by the short composite beam exceeded that of the long composite beam. With respect to GTSDWA-1.0, the resistance due to the left and right composite beams was similar. All three specimens underwent the flexure mechanism and flexure–axial mixed mechanism stages. They resisted the external load mainly via the flexure mechanism. Moreover, the addition of stiffeners on both sides of the top and seat angles is advantageous in terms of improving the collapse resistance and ductility of unequal span composite substructures.
Wei-hui Zhong,Zheng Tan,Li-Min Tian,Bao Meng,Yu-hui Zheng,Shi-chao Daun 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.41 No.5
To elucidate the differences in the collapse behavior between a single-story beam-column assembly and multi-story frame, two 1/3-scale two-bay composite frames, including a single-story composite beam–column assembly and a three-story composite sub-frame, were designed and quasi-statically tested. The load–displacement responses, failure modes, and internal force development of the two frames were analyzed and compared in detail. Furthermore, the resistance mechanisms of the two specimens were explored, and the respective contributions of different load-resisting mechanisms to the total resistances were quantitatively separated to gain deeper insights. The experimental tests indicated that Vierendeel action was present in the two-dimensional multi-story frames, which led to an uneven internal force distribution among the three stories. The collapse resistance of TSDWA-3S in the flexural stage was not significantly increased by the structural redundancy provided by the additional story, as compared to that of TSDWA-1S. Although the development of the load response was similar in the two specimens at flexural stage, the collapse mechanisms of the multi-story composite frame were much more complicated than those of the single-story beam–column assembly, and the combined action between stories was critical in determining the internal force redistribution and rebalancing of the remaining structure.
Di, Bao-Shan,Wei, Kong-Ping,Tian, Jin-Hui,Xiao, Xiao-Juan,Li, Yan,Zhang, Xu-Hui,Yu, Qin,Yang, Ke-Hu,Ge, Long,Huang, Wen-Hui,Zhang, Fang-Wa Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8
Background: Our aim was to conduct a meta-analysis to compare the efficacy and safety of pemetrexed and docetaxel for non-small cell lung cancer (NSCLC). Materials and Methods: We systematically searched the Cochrane Library, PubMed, Embase, China Biology Medicine Database for randomized controlled trials (RCTs) comparing the efficacy and toxicities of pemetrexed versus docetaxel as a treatment for advanced NSCLC. We limited the languages to English and Chinese. Two reviewers independently screened articles to identify eligible trials according to the inclusion and exclusion criteria and assessed the methodological quality of included trials, and then extracted data. The meta-analysis was performed using STATA12.0. Results: Six RCTs involving 1,414 patients were identified. We found that there was no statistically significant differences in overall response rate, survival time, progression-free survival, disease control rate, and 1-2yr survival rate (p>0.050) but it is worthy of mention that patients in the pemetrexed arms had significantly higher 3-yr survival rate (P=0.002). With regard to the grade 3 or 4 hematological toxicity, compared with docetaxel, pemetrexed led to lower rate of grade 3-4 febrile neutropenia, neutropenia, and leukocyts toxicity (p<0.001). There was no significant difference in anemia between the two arms (p=0.08). In addition, pemetrexed led to higher rate of grade 3-4 thrombocytopenia toxicity (p=0.03). As for the non-hematological toxicities, compared with docetaxel, pemetrexed group had lower rate of grade 3-4 diarrhea and alopecia. Conclusions: Pemetrexed was almost as effective as docetaxel in patients with advanced NSCLC. At the same time, pemetrexed might increase the 3-yr survival rate. As for safety, pemetrexed led to lower rate of grade 3-4 febrile neutropenia, neutropenia, leukocytes, diarrhea and alopecia toxicity. However, it was associated with a higher rate of grade 3-4 thrombocytopenia.
Xylaroisopimaranin A, a New Isopimarane Derivative from an Endophytic Fungus Xylaralyce sp.
Shang-Song Bao,Hui-Hui Liu,Xue-Qing Zhang,Cheng-Xiong Liu,Xiao-Cong Li,Zhi-Yong Guo 한국생약학회 2019 Natural Product Sciences Vol.25 No.3
Five secondary metabolites, including a new isopimarane derivative xylaroisopimaranin A (1), were isolated from the endophytic fungus Xylaralyce sp. (HM-1), and their structures were elucidated by 1D, 2D NMR, MS and CD spectra. Their bioactivities were performed to antibacterial, Hep G2 cells cytotoxicity and brine shrimp inhibition. The biological evaluation results showed that the xylaroisopimaranin A (1), xylabisboein B (2), griseofulvin (3) , 5-methylmellein (4) and mellein-5-carboxlic acid (5) displayed no significant Hep G2 cells cytotoxicity and antibacterial acitivity, but they inhibited the brine shrimp with IC50 from 0.5 to 25 μmol/mL.
Acupuncture for Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis
Bao-yong Lai,Hui-juan Cao,Guo-yan Yang,Li-yan Jia,Suzanne Grant,Yu-tong Fei,Emma Wong,Xin-lin Li,Xiao-ying Yang,Jian-ping Liu 대한남성과학회 2019 The World Journal of Men's Health Vol.37 No.3
ChinaPurpose: To assess the effectiveness and safety of acupuncture for erectile dysfunction (ED).Materials and Methods: We searched six major English and Chinese databases included randomized controlled trials (RCTs) testing acupuncture alone or in combination for ED. Dichotomous data were presented as risk ratio (RR) and continuous data were presented as mean difference (MD) both with 95% confidence interval (CI). The Revman (v.5.3) was used for data analyses. Quality of evidence across studies was assessed by the online GRADEpro tool.Results: We identified 22 RCTs, fourteen of them involving psychogenic ED. Most of the included RCTs had high or unclear risk of bias. There was no difference between electro-acupuncture and sham acupuncture with electrical stimulation on the rate of satisfaction and self-assessment (RR, 1.50; 95% CI, 0.71–3.16; 1 trial). Acupuncture combined with tadalafil appeared to have better effect on increasing cure rate (RR, 1.31; 95% CI, 1.00–1.71; 2 trials), and International Index of Erectile Function-5 scores (MD, 5.38; 95% CI, 4.46–6.29; 2 trials). When acupuncture plus herbal medicine compared with herbal medicine alone, the combination therapy showed significant better improvement in erectile function (RR, 1.68; 95% CI, 1.31–2.15; 7 trials). Only two trials reported facial red and dizziness cases, and needle sticking and pruritus cases in acupuncture group. Conclusions: Low quality evidence shows beneficial effect of acupuncture as adjunctive treatment for people mainly with psychogenic ED. Safety of acupuncture was insufficiently reported. The findings should be confirmed in large, rigorously designed and well-reported trials.
Highly Chemo- and Regioselective Reaction of Hydroxybenzenes in Acidic Ionic Liquid
Hui Guo,Yu Wei Zhuang,Jian Cao,Guo Bao Zhang 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.9
Highly chemo- and regioselective reaction of hydroxybenzenes with α,β-unsaturated compounds in acidic ionic liquid l-butyl-3-methylimidazolium hydrogen sulphate ([BMIM]HSO4) was reported for the first time. A series of oxa-Michael adducts and Friedel-Crafts alkylated products were synthesized with good yields. The acidic ionic liquid could be easily recycled for at least 5 times with only minor loss in activity.
Bao-Dong Song,Hui Ding,Shi-Chang Wang 한국생물공학회 2007 Biotechnology and Bioprocess Engineering Vol.12 No.2
In this study, we investigated the hydrolysis of olive oil catalyzed by a surfactant-coated Candida rugosa lipase in a hydrophilic polyacrylonitrile hollow fiber membrane reactor and then compared the results to those using the native lipase. The organic phase was passed through the hollow inner fibers of the reactor, and consisted of either the coated lipase and olive oil dissolved in isooctane or the coated lipase dissolved in pure olive oil. The aqueous phase was pumped through the outer space. After 12 h and with conditions of 30℃, 0.12 mg enzyme/mL and 0.62 M olive oil, the substrate conversion of the coated lipase reached 60%. This was twice the conversion for the same amount of native lipase that was pre-immobilized on the membrane surface. When using pure olive oil, after 12 h the substrate conversion of the coated lipase was 50%, which was 1.4 times higher than that of the native lipase.
Analysis and Modeling of AC–AC Switched Capacitor Converters
Hui Cai,Liting Bao,Qian Guo,Ying Wang,Weimin Chen 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.1
A new modeling method for AC–AC switched capacitor converters (SCCs) is introduced in this study. The proposed analyticalmethod aims to accurately describe the input–output characteristics of AC–AC SCCs and establish a mathematical model forstatic voltage conversion ratio and equivalent resistance, which are key performance metrics for SCCs. A quantitative analysis ofconverter regulation capability is addressed on the basis of the modeling method. In this analysis, the effects of the controlparameters and individual components on SCCs are illustrated extensively. Component stresses, such as the peak value andtransient variation of the voltage/current of the converter, are also presented. The effectiveness of the proposed method is verifiedby comparing it with the existing modeling method and applying it to an AC–AC SCC with a conversion ratio of three. Two 1kW prototypes are built in a laboratory, and their experimental results exhibit good agreement with the theoretical analysis.
Eco-friendly Polypyrrole-coated Cocozelle Composites for Supercapacitor Application
Hui Ji,Chuanjie Zhang,Weida Rao,Bin Guo,Lingling Fan,Zikui Bai,Haifeng Bao,Jie Xu 한국섬유공학회 2020 Fibers and polymers Vol.21 No.6
Cocozelle is essentially consisted of hemicellulose and lignin with a hierarchically porous structure. Herein,cocozelle slices after freeze-drying were employed as green substrates to support the growth of polypyrrole (PPy) via a facileoxidative polymerization approach. The cocozelle surface was densely covered with sheet-like PPy due to the hydrogenbonding between PPy and cocozelle. The PPy/cocozelle composites could be facilely utilized as supercapacitor electrodes,which showed a high specific capacitance of 1108 F g-1 with an energy density of 70.5 Wh kg-1 and a power density of398 W kg-1 at a charge/discharge current density of 0.8 mA cm-2 as well as desirable cycling life with a capacitance retentionrate of 76.9 % after 1000 cycles. Moreover, 95.3 % of the initial specific capacitance obtained at 0.2 mA cm-2 could bereached as the current density increased to 1.6 mA cm-2. These results demonstrate that cocozelle could be used as a superioralternative biomass-derived substrate for the developments of eco-friendly and renewable energy storage devices.