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Endoscopic Balloon Dilation for Treatment of Congenital AntralWeb
Jacquelin Peck,Racha Khalaf,Ryan Marth,Claudia Phen,Roberto Sosa,Francisco Balsells Cordero,Michael Wilsey 대한소아소화기영양학회 2018 Pediatric gastroenterology, hepatology & nutrition Vol.21 No.4
Congenital antral webs are a rare but relevant cause of gastric outlet obstruction in infants and children. The condition may lead to feeding refusal, vomiting, and poor growth. Due to the relative rarity of the disease, cases of congenital antral web are frequently misdiagnosed or diagnosed with significant delay as physicians favorably pursue diagnoses of pyloric stenosis and gastric ulcer disease, which are more prevalent. We report a case of an eight-month-old female who presented with persistent non-bilious emesis, feeding difficulties, and failure to thrive and was discovered to have an antral web. The web was successfully treated with endoscopic balloon dilation, which resolved her symptoms. Two years later, the patient remains asymptomatic and is thriving with weight at the 75th percentile for her age.
Photochemistry of norharmane in aqueous solution
Gonzalez, M. Micaela,Salum, M. Laura,Gholipour, Yousef,Cabrerizo, Franco M.,Erra-Balsells, Rosa Korean Society of Photoscience 2009 Photochemical & photobiological sciences Vol.8 No.8
The photochemistry of norharmane (9H-pyrido[3,4-b]indole) in acidic (pH $5.0{\pm}0.1$) and alkaline (pH $10.0{\pm}0.1$) aqueous solutions was studied. The photochemical reactions were monitored by TLC, UV/VIS absorption spectroscopy, high-performance liquid chromatography (HPLC), electronic ionization-mass spectrometry (EI-MS), UV-laser desorption/ionization-time of flight-mass spectrometry (UV-LDI-TOF-MS) and an enzymatic method for $H_2O_2$ determination. The neutral (nHoN) and the protonated ($nHoH^+$) forms of norharmane irradiated under Ar atmosphere were photostable, but they suffered a photochemical transformation in the presence of $O_2$, yielding as photoproducts norharmane dimers, trimers and tetramers. nHoN shown to be more photostable than $nHoH^+$. The $nHoH^+$ and nHoN consumption quantum yields were $1.82{\times}10^{-3}$ and $0.51{\times}10^{-3}$, respectively, and the mechanisms involved in its photochemistry are discussed. $H_2O_2$ and singlet oxygen ($^1O_2$) were also detected and quantified in irradiated solutions of norharmane, and their role in the photochemistry of norharmane is discussed.
Endoscopic Balloon Dilation for Treatment of Congenital Antral Web
Peck, Jacquelin,Khalaf, Racha,Marth, Ryan,Phen, Claudia,Sosa, Roberto,Cordero, Francisco Balsells,Wilsey, Michael The Korean Society of Pediatric Gastroenterology 2018 Pediatric gastroenterology, hepatology & nutrition Vol.21 No.4
Congenital antral webs are a rare but relevant cause of gastric outlet obstruction in infants and children. The condition may lead to feeding refusal, vomiting, and poor growth. Due to the relative rarity of the disease, cases of congenital antral web are frequently misdiagnosed or diagnosed with significant delay as physicians favorably pursue diagnoses of pyloric stenosis and gastric ulcer disease, which are more prevalent. We report a case of an eight-month-old female who presented with persistent non-bilious emesis, feeding difficulties, and failure to thrive and was discovered to have an antral web. The web was successfully treated with endoscopic balloon dilation, which resolved her symptoms. Two years later, the patient remains asymptomatic and is thriving with weight at the 75th percentile for her age.