Patients with celiac disease are at high risk of developing metabolic syndrome and fatty liver

( Ashish Agarwal ),( Alka Singh ),( Wajiha Mehtab ),( Vipin Gupta ),( Ashish Chauhan ),( Mahendra Singh Rajput ),( Namrata Singh ),( Vineet Ahuja ),( Govind K. Makharia ) 대한장연구학회 2021 Intestinal Research Vol.19 No.1

Background/Aims: Gluten-free diet has an excess of fats and simple sugars and puts patients with celiac disease at risk of metabolic complications including metabolic syndrome and fatty liver. We assessed prevalence of metabolic syndrome and fatty liver in two cohorts of celiac disease. Methods: Study was done in 2 groups. In group 1, 54 treatment naïve patients with celiac disease were recruited. Of them, 44 returned after 1-year of gluten-free diet and were reassessed. In group 2, 130 celiac disease patients on gluten-free diet for ≥1 year were recruited. All patients were assessed for anthropometric and metabolic parameters and fatty liver. Metabolic syndrome was defined as per consensus definition for Asian Indians. Fatty liver was defined as controlled attenuation parameter value >263 decibels by FibroScan. Results: In group 1, of 44 treatment naïve patients with celiac disease, metabolic syndrome was present in 5 patients (11.4%) at baseline and 9 (18.2%) after 1 year of gluten-free diet. Patients having fatty liver increased from 6 patients (14.3%) at baseline to 13 (29.5%) after 1year of gluten-free diet (P=0.002). In group 2, of 130 patients with celiac disease on gluten-free diet for a median duration of 4 years, 30 out of 114 (26.3%) and 30 out of 130 patients (23%) had metabolic syndrome and fatty liver, respectively. Conclusions: Patients with celiac disease are at high risk of developing metabolic syndrome and fatty liver, which increases further with gluten-free diet. These patients should be assessed for nutritional and metabolic features and counseled about balanced diet and physical activity regularly. (Intest Res 2021;19:106-114)

Effect of Ba and Ho co-doping on crystal structure, phase transformation, magnetic properties and dielectric properties of BiFeO3

Jogender Singh, Ashish Agarwal,Ashish Agarwal,Sujata Sanghi,Tanvi Bhasin,Manisha Yadav,Umesh Bhakar,Ompal Singh 한국물리학회 2019 Current Applied Physics Vol.19 No.3

Multiferroics having composition Bi0.80-xBa0.20HoxFeO3 (BBFO, BBHFO5, BBHFO10, BBHFO15 and BBHFO20 for x=0.0, 0.05, 0.10, 0.15 and 0.20 respectively) were synthesized by method of solid state reaction. The crystal structure has been studied using X-ray diffraction technique. The X-ray patterns show enormous transform in crystal structure at concentration x=0.20. The Rietveld refinement of XRD patterns indicates that at concentration x=0.0 sample have rhombohedral structure with R3c space group while for the concentration x=0.05, 0.10, 0.15 and 0.20, the mixed phase including rhombohedral R3c and triclinic P1 space groups were obtained with best fitting. This phase transformation in crystal structure is observed due to mismatching of ionic radii of doped ions and parent ions. Magnetic properties of all samples were carried out by using vibrating sample magnetometry. M-H hysteresis loops shows that with doping of Ba and Ho antiferromagnetic BiFeO3 (BFO) transforms into ferromagnetic. The dielectric and ferroelectric measurements were carried out which shows that dielectric constant, dielectric loss and ferroelectric properties are enhanced with co-doping of Ho in comparison of the pristine BFO due to structure deformation and decrease in oxygen vacancies with higher concentration of Ho. Significant improvement has been observed in dielectric constant and remnant magnetization values with increasing content of Ho and decrease in the dielectric loss.

The effect of attack of chloride and sulphate on ground granulated blast furnace slag concrete

Ashish, Deepankar K.,Singh, Bhupinder,Verma, Surender K. Techno-Press 2016 Advances in concrete construction Vol.4 No.2

This concrete is one of the most versatile construction material widely used for almost a century now. It was considered to be very durable material and required a little or no maintenance since long time. The assumption is very true, except when it is subjected to highly aggressive environments. The deterioration of concrete structures day by day due to aggressive environment is compelling engineers to assess the loss in advance so that proper preventive measure can be taken to achieve required durability to concrete structures. The compounds present in cement concrete are attacked by many salt solutions and acids. These chemicals are encountered by almost all concrete structures. The present study has been undertaken to investigate the effect of attack of chlorides and sulphates with varying severity on compressive strength of ground granulated blast furnace slag (GGBFS) concrete after immersion in salt solution for 28 days. The results indicate that the durability of GGBFS concrete increases with the increase in percentage replacement of cement by GGBFS for 20% and then gradually decreases with increases in percentage of GGBFS with cement (as in the study for 40% and 60%). Also there is increase in strength of GGBFS concrete with increase in age. Thus the durability of concrete improves when GGBFS is added as partial replacement of cement. In this study the strength of GGBFS concrete is less affected by chemicals as compared to conventional concrete when exposed to aggressive environment.

Anomaly Recognition in Online Social Networks

Ashish Rawat,Gunjan Gugnani,Minakshi Shastri,Pardeep Kumar 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.7

The popularity of social networking sites has increased throughout the decade and everything that gains immense popularity with great human involvement also brings many challenges and issues along with it. Similarly the excessive use of online social networking causes a great increase in anomalies. In social networking the anomalies are like fake account, account hack, identity theft, spams and many other illegitimate activities. It is thus necessary to detect such anomalous and suspicious behavior of any user at these social platforms, as they could have an adverse impact on users, especially on teenagers. In this paper, we propose various methodologies for early detection of suspicious and anomalous activities. We have done the analysis of various parameters of social networking and its graph like indegree, outdegree, active time of a node (user) and its behavior.

Advent and Maturation of Regenerative Medicine

Ashish Agarwal 한국조직공학과 재생의학회 2013 조직공학과 재생의학 Vol.10 No.4

The field of regenerative medicine (RM), encompassing stem cell (SC) technologies, therapeutics, tissue engineering (TE), biomaterials, scaffolds and other enabling technologies provides a wide gamut of tools and tracks to combat, manage and hopefully cure serious human and animal injuries, dysfunctions and diseases. This review illustrates the trends that are becoming the major platforms in this field. The last 10 years in itself has seen major definitive observations, including multi-track directives of adult stem cell translational technologies, tissue and organ engineering protocols, iPS cell applications and understanding of the role of cancer stem cells to develop effective anti-cancer regimens. With the rapid advances of RM translational research, further advances are expected to be implemented for personalized repair and curative outcomes. RM future is bright although laden with challenges of global fragmentation which needs coherent consolidation, stringent cost and time effective regulation and long-term funding mechanisms, so clinical and diagnostic solutions are realized and recognized to combat unmet medical needs.

Qualitative uncertainty principle for Gabor transform

Ashish Bansal,Ajay Kumar 대한수학회 2017 대한수학회보 Vol.54 No.1

We discuss the qualitative uncertainty principle for Gabor transform on certain classes of the locally compact groups, like abelian groups, $\R^n\times K$, $K \ltimes \R^n$ where $K$ is compact group. We shall also prove a weaker version of qualitative uncertainty principle for Gabor transform in case of compact groups.

Micro-structural and temperature dependent electrical characterization of Ni/GaN Schottky barrier diodes

Ashish Kumar,Seema Vinayak,R. Singh 한국물리학회 2013 Current Applied Physics Vol.13 No.6

Micro-structural investigation of Ni/GaN Schottky barrier diodes has been carried out using highresolution transmission electron microscopy and electron diffraction spectrum in order to emphasize the role of Ni/GaN interface in controlling the Schottky diode behavior. Variable temperature Hall effect measurement of GaN samples along with the currentevoltage (IeV) characteristics of Ni/n-GaN Schottky barrier diodes have been measured in 100e380 K temperature range. Results are analyzed in terms of thermionic emission theory by incorporating the concept of barrier inhomogeneity at the metal/semiconductor interface. The observed anomaly of temperature dependence of Schottky barrier height and ideality factor are explained by invoking two sets of Gaussian distribution of SBH in the temperature ranges of 100e180 K and 220e380 K, respectively. The value of A** (effective Richardson constant) as determined from the modified Richardson plot is 29.2 A/(cm2 K2), which shows an excellent agreement with the theoretical value (26.4 A/(cm2 K2)) in the temperature range of 220e380 K.

Synthesis, structural and optical characterization of nanocrystalline ZnS:Cu embedded in silica matrix

Ashish Tiwari,S.A. Khan,R.S. Kher 한국물리학회 2012 Current Applied Physics Vol.12 No.3

The synthesis of Cu doped ZnS nanoparticles inside the pore of an inorganic silica gel matrix is presented. The synthesized nanoparticles were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray (EDX). X-ray diffraction pattern reveals the crystalline wurtzite phase of ZnS. The existence of silica gel in modeling morphologies of the nanoparticles was characterized using Fourier transform infrared (FTIR) spectrometer. Thickness of the silica shell was also calculated. UV- absorption spectrum shows the appearance of an absorption peak at 273 nm which confirms the blue shift as compared to that of bulk ZnS. The photoluminescence (PL) emission spectrum of the sample showed a broad band in the range 465e510 nm due to the transition from the conduction band edge of ZnS nanocrystals to the acceptor like t2 state of Cu. The synthesis of Cu doped ZnS nanoparticles inside the pore of an inorganic silica gel matrix is presented. The synthesized nanoparticles were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray (EDX). X-ray diffraction pattern reveals the crystalline wurtzite phase of ZnS. The existence of silica gel in modeling morphologies of the nanoparticles was characterized using Fourier transform infrared (FTIR) spectrometer. Thickness of the silica shell was also calculated. UV- absorption spectrum shows the appearance of an absorption peak at 273 nm which confirms the blue shift as compared to that of bulk ZnS. The photoluminescence (PL) emission spectrum of the sample showed a broad band in the range 465e510 nm due to the transition from the conduction band edge of ZnS nanocrystals to the acceptor like t2 state of Cu.

Visualization of Microfluid Flow in Evaporating Droplets for Self-Assembly Control of Nanoparticles

Ashish Kumar Thokchom,Qitao Zhou,Jungyu Park,Dogyeong Ha,Taesung Kim 한국가시화정보학회 2017 한국가시화정보학회 학술발표대회 논문집 Vol.2017 No.11

Ruthenium doped carbon aerogel with CO2 surface activation for enhanced electrochemical capacitance

Ashish Singh,D.K. Kohli,Sushmita Bhartiya,Rashmi Singh,M.K. Singh,P.K. Gupta 한국물리학회 2017 Current Applied Physics Vol.17 No.6

With the aim of enhancement of electrochemical capacitance, CO2 activation of carbon aerogel (CA) prepared by polycondensation of resorcinol with formaldehyde was performed to obtain activated carbon aerogel (ACA) having improved surface area properties. Ruthenium oxide nano-particles were loaded by impregnation method for utilizing pseudo-capacitive property of ruthenium oxide (RuO2) and the effect of activation treatment was studied. RuO2 loading of 20% by weight was accomplished in CA and ACA to synthesize RuO2 doped carbon aerogel (CA/RuO2) and activated carbon aerogel (ACA/RuO2). While the specific capacitance of carbon aerogel improved from 95 to 153 F/g on activation, RuO2 loading further led to enhancement in capacitance and specific capacitance of 308 F/g was obtained for ACA/ RuO2. The studies being important for Ru economy, showed the influence of surface area enhancement of base matrix in achieving high specific capacitance.