서울·경기지역 병원직원의 혈액매개 감염노출에 대한 다기관 조사연구

박미라,김정은,박은숙,최정실,정선영,송영구,홍성관,김준명,허애정,양동규,조영주 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

견/합성섬유 혼방품의 일욕염색(Ⅵ) : 산성염료/분산염료 염욕에서의 견/셀룰로오스 트리아세테이트의 염착거동 Adsorption Behavior of Acid Dyes/Disperse Dyes on Silk/Cellulose Triacetate

金公朱,박미라,강영의,김애순 全北大學校 1994 論文集 Vol.38 No.-

In one bath dyeing system of silk/cellulose triacetate(triactate) fiber blend fabric with acid/disperse dyes, adsorption behvior of acid dyes and disperse dyes on silk and triactate fabrics were examined. In the dyeing of triactate with the C.I. Disperse Red 19(Red 19) and the C.I. Disperse Red 60(Red 60) at 100℃, dye uptake with the Red 19 was higher than that with the Red 60. When the silk/triaceetate was dyed with Red 19 and the Red 60 at 100℃, dye uptake on triacetate was influenced by affinity of the dye to the silk fabric dyed together. In the treatment of the silk fabric dyed with the Red 19 and Red 60 in desorption bath with and without undyed triacetate, desorption of the dyes from the silk fabric was influenced by the affinity of the dyes to the triacetate. When the silk/triacetate was dyed with the Blue 80/Red 19 and Red 60 at 100℃, color of triacetate dyed with the Red 19 and Red 60 was not influenced by the Blue 80 but silk dyed with the Blue 80 was influenced by the Red 19.

중환자실 병원감염에 대한 다기관 공동 조사연구

박은숙,박미라,진혜영,김정은,최정실,송영구,최영화,이위교,홍성관,허애정,양동규,김준명 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

효과적인 우유 섭취지침에 관한 연구

신현아;이애정;이지선;우혜임;조아라;채유진;엄애선 한양대학교 2010 韓國 生活 科學 硏究 Vol.30 No.1

Over the past decade, there has been growing scientific evidence that dietary milk plays a role in beneficial effects for human health. Milk provides a number of good ingredients, in particular with growth factors and different types of proteins such as α -lactalbumin and β-casein. As well as essential amino acids of leucine and isoleucine are make to a positive way of human physical conditions. Therefore, those ingredients are directly involved in the human body, fluid composition and involved in metabolism of protein or carbohydrate. In addition, the development of physical strength and bone health associated with milk consumption. Thus, milk is one of good food for prevention of osteoporosis. Nowadays, several dietary guidelines suggest that people should intake two or three cups of dairy products including milk a day. However, some people cannot drink milk because they appear many adverse effects with regard to intake of milk like allergic reactions, lactose intolerance and weight gain problem. Consequently, it is worthy to discuss about these matters. Person pose the health problems regarding milk consumption should select dairy products carefully. Milk substitutes such as partially-hydrolyzed formula, yogurt, cheese and non- and low-fat dairy products are suggested. They prevent the allergy and lactose intolerance due to lactase in fermented milk digesting the lactose into glucose and galactose. Taking all of these into account, milk consumption is very important to maintain the human health. Although there are several adverse effects with regard to milk consumption, it would not be shown any health problem only if it follows the milk dietary guidelines. Therefore, a milk drinking should be actively encouraged for the public health.

지지율(支持率)의 차에 대한 신뢰구간 : 여론조사를 중심으로

최규정,이장재,최애라 조선대학교 통계연구소 2000 統計硏究所論文誌 Vol.2 No.1

일반적으로 응답자가 민감한 속성을 가지고 있지 않으면 직접 "예"라고 응답하고, 민감한 속성을 가지고 있으면 Greenberg et.al (1969)의 무관질문모형의 확률장치를 이용하여 선택된 질문에 응답을 하는 새로운 무관확률화응답모형을 써서 모집단의 비율Ⅱ을 추정하기 위하여 표본의 비율 p^^를 생각하면, 95%신뢰수준에서는 1.96×se(p^^)≤오차의 한계로부터 계산된다. 그러면 문제는 se(p^^)가 될 것이다. 그러나 여론조사의 경우 모집단이 K개의 범주로 나누어지고 각각 비율이 Ⅱ_1,Ⅱ_2,…,Ⅱ_k일 때, 그리고 표본에서의 비율을 P_1,P_2,…,P_k라 하면, 실제의 관심은 가장 큰 두개의 비율(Ⅱ_1,Ⅱ_2라 하자)의 차이에 대하여 연구자가 원하는 만큼의 신뢰수준과 오차의 한계를 갖는 표본의 크기를 원한다. 따라서 정해진 신뢰수준과 오차의 한계를 갖는 표본의 크기를 원한다. 따라서 정해진 신뢰수준과 오차의 한계를 얻기 위한 표본의 크기는 se(P^^_1 - P^^_2)에 대한 이론이다.

정신분열병의 유전적 고위험군에서 인지, 정서 및 사회기능 연구

이경진,위휘,유소영,이애라,송지연,하태현,홍경수,김명선,권준수 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.1

Objectives : Vulnerability marker in biological relatives of schizophrenia may be very useful in identifying the propensity for the development of schizophrenia. This study suggests that the relatives at risk for genetically developing schizophrenia have impairments in several domains of cognition, social function and affective function as a vulnerability marker. Methods : A neurocognitive function test, a social function test and an affective function test were administered to fifteen healthy relatives from families with two or more patients with schizophrenia (geneticallly high risk subjects). Fifteen healthy controls matched for age and gender were recruited in this study. Results : Compared to the control subject, the genetic high risk subjects performed significantly more poorly in the selective attention and recall memory of neurocognitive function. The high dsk subjects also had lower scores in independence-performance and independence-competence of the social function test and emotion control of the affective function test. Conclusion : Selective attention, recall memory, independence-performance, independence-competence and emotion control ability may be a valuable marker for genetic study of schizophrenia.

정신분열병의 임상적 고위험군의 특징 : '서울청년클리닉'의 자연 추적 관찰 예비연구

유소영,이경진,강도형,이승재,하태현,위휘,이애라,송지연,김성년,권준수 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.1

Objectives : The aims of this study were to identify the intake and following process for subjects at high risk of transition to schizophrenia and to examine the neurocognitive, social, and emotional functions of the subjects compared with healthy controls. Methods : Symptomatic individuals judged at high risk for schizophrenia ('clinical high risk') within Youth Clinic were assessed and followed up. They performed a neurocognitive function test, a social function test and an affective function test. Twenty healthy controls were recruited in this study. Results : Among eighty-two subjects contacted through the Youth clinic, sixteen subjects were judged as the clinical high risk group. Fourteen subjects among the clinical high risk group showed deficits in several domains of neurocognitive functions, such as visual recall memory, verbal short term memory and executive function. Social and affective functions are also impaired in the Cli-nical high risk group compared with healthy controls. Two of 15 subjects (13%) developed a psychotic disorder within 6 months. Conclusion : This study illustrates the state of follow-up study for a clinical high risk group. Despite low numbers and short durations, some impairment of several functions in the clinical high risk group suggests possible predictors of psychosis.

The Connection between Hand Washing and Brushing Teeth

Ra-Ae Bak,Sun-Jung Shin,Hee-Jung Park,Jin-Young Jung,Hwa-Young Lee,Nam-Hee Kim 한국치위생과학회 2023 치위생과학회지 Vol.23 No.2

Background: The purpose of this study was to identify the connection between handwashing and toothbrushing, focusing on eating habits, and to verify whether eating habits can be used as an action cue for forming health habits.Methods: This was a cross-sectional study using secondary data from the 2019 community health survey. The participants included 229,099 adults aged 19 years or older, representative of the South Korean people. We employed two dependent variables: one was washing hands, and the other was brushing teeth. Eating habits was a major independent variable. Socioeconomic variables, such as age, gender, income, occupation, economic activity, education, and residence were adjusted as confounders. Multivariate logistic regression was performed to calculate adjusted odds ratio and 95% confidence intervals. Results: Most of the participants had good health behaviors: those who wash their hands and brush their teeth were each approximately 80%. Our finding indicated that brushing teeth and washing hands can be connected with eating habits. After adjusting for confounders, it was found that people who wash their hands before meals (compared to those who did not wash their hands before meals) had a higher toothbrushing rate after meals (i.e., socioeconomic status) (Adjusted Odds Ratio: 2.0, Confidence Intervals: 1.9 to 2.1). Conclusion: Those who practice either washing hands before meals or brushing teeth after meals were found to have a connection between washing hands and brushing teeth based on the results of practicing other health behaviors. This implies that eating habits can be connected as a behavior cue to promote health habits, such as washing hands before meals and brushing teeth after meals.

Poster Session : PS 0816 ; Upper GI Tract : Third-Line Rescue Therapy with Moxifl oxacin or Levofl oxacin-Based Triple Regimen for Helicobacter pylori Infection in Area with High Quinolone-Resistance

( Ae Ra Lee ),( Dong Ho Lee ),( Jae Jin Hwang ),( Hyuk Yoon ),( Cheol Min Shin ),( Young Soo Park ),( Na Young Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: The recent increase in resistance of H. pylori against fl uoroquinolone has become a signifi cant limitation in effective eradication. The aim of this study was to evaluate the effi cacy and tolerability of quinolone-based third-line rescue therapy for H. pylori. Methods: From April 2003 to December 2013, a total 63 patients who experienced two consecutive eradication failures were included in this study. They received a 7-day standard triple regimen with proton pump inhibitor (PPI) (standard dose b.i.d.), amoxicillin (1000 mg b.i.d) plus either moxifl oxacin (400mg q.d.) (PAM group, n = 28) or levofl oxacin (500mg b.i.d.) (PAL group, n = 35) as a third-line rescue therapy for H. pylori. H. pylori eradication was evaluated by the 13C-urea breath test, histology, or the rapid urease test. The eradication rate, drug compliance, and adverse event rates were compared between the two groups. Results: The eradication rates by intention-to-treat analysis were 39.3% (11/28) and 57.7% (15/35) in the PAM group and the PAL group, respectively (P = 0.802). Theeradication rates by per-protocol analysis were 45.8% (11/24) and 45.5% (15/33) inthe PAM group and the PAL group, respectively (P = 1.000). Compliance was good in the both groups (PAM/PAL group: 87.5%/93.9%). The adverse event rates were reported in 45.8% (11/24) and 15.2% (5/33) in the PAM group and the PAL group, respectively (P = 0.017). Conclusions: Effi cacy of quinolone-based third-line regimen has recently decreasing in Korea. Reconsiderations on fl uoroquinolone containing rescue therapy for H. pylori is needed in the future.

Flavonoids Differentially Modulate Nitric Oxide Production Pathways in Lipopolysaccharide-Activated RAW264.7 Cells

Ae Ra Kim,Jae Youl Cho,Yani Zou,Jae Sue Choi,Hae Young Chung 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.3

Naturally occurring flavonoids are known to modulate various inflammatory and immune processes. Based on structural property, in this study, molecular mechanism of flavonoids in modulating nitric oxide (NO) production and its signaling pathway were investigated using lipopolysaccharide (LPS)-activated RAW264.7 cells. Although flavonol-typed flavonoids (kaempferol and quercetin) more potently scavenged reactivity of nitric oxide (·NO) as well as peroxynitrite (ONOO-) than isoflavones (genistein and genistin), kaempferol, quercetin and genistein showed a little difference in inhibition of both inducible NO synthase expression and NO production, with IC50 values of 13.9, 20.1 and 26.8 µM. However, there was a striking pattern related to structural feature in modulation of LPS-mediated signaling pathways. Thus, flavonols only inhibited transcription factor AP-1 activation, whereas isoflavones suppressed the DNA binding activation of NF-κB and C/EBPβ. Therefore, these data suggest that structural feature may be linked to decide drugs target molecule in LPS-mediated signaling pathways, rather than its potency.