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Non-Value-added Activity 개선을 통한 간호업무 효율성 향상
박양희,권인각,박계숙,장혜정,송미라,김희진,Park, Yang-Hee,Kwon, In-Gak,Park, Kyei-Sook,Jang, Hae-Jung,Song, Mi-Ra,Kim, Hee-Jin 한국의료질향상학회 2013 한국의료질향상학회지 Vol.19 No.2
Background: This study investigates improvements in non-value-added nursing activities in clinical work, in order to improve the efficiency and quality of nursing activities. Methods: The study was performed as a quality improvement project at a tertiary general hospital. The nursing activities that needed improvements were categories into admission care, discharge care, supply management, diagnostic work-up related activities, and others. The nursing time and frequency of non-value-added activities were compared across nine nursing units before and after implementation of the quality improvement program. Post-implementation patient and nurse satisfaction were subsequently analyzed. Result: Post-implementation, the time spent on non-value-added nursing activities was reduced and patients and nurses were satisfied with the improvements. Discussion: Reducing non-value-added activities in nursing can increase the work efficiency and ensure time for patient care, thus improving the quality of nursing care. For further study, accurate surveys on nursing activities based on nursing time are required.
물고추냉이 뿌리-조직 바이오센서에 의한 과산화수소의 정량에 관한 연구
박양희 ( Yang Hee Park ),권효식 ( Hyo Shik Kwon ) 충북대학교 과학교육연구소 2011 과학교육연구논총 Vol.26 No.2
The response characteristics of the new biosensor developed by the co-immobilization of Wasabia Japonica root tissue and ferrocene in a carbon paste matrix for the amperometric determination of hydrogen peroxide were evaluated. In the range of electrode potential examined(-0.30~0.00 V vs. Ag/AgCl), and it responded in the wide range of pH and its biocatalytic stability was superior. Also, it`s detection limit was 2.5×10-6M (S/N=3) and it had relatively good selectivity to the materials considered to disturb the response. The result of this biosensor study using Wasabia Japonica root tissue can be utilized as the basic information for the determination of hydrogen peroxide.
인공피부모델을 이용한 트라넥삼산 제형의 피부투과도 및 자극 평가
박양희 ( Yang Hui Park ),장원희 ( Won Hee Jang ),정경미 ( Kyoung Mi Jung ),이수현 ( Su Hyun Lee ),임경민 ( Kyung Min Lim ) 한국동물실험대체법학회 2012 동물실험대체법학회지 Vol.6 No.1
The skin permeability of active ingredient is one of the most important issues for designing transdermal administration form. At the same time, the formulation should be non-irritant to skin. To evaluate skin permeability and irritancy, various methods have been proposed and ex vivo skin is the tool recommended by regulators. However its use is time consuming and requires numerous human donors. Owing to the similarity to real skin, reconstructed human epidermis model have been recognized as a useful tool. We simultaneously evaluated the permeability and irritancy of tranexamic acid in transdermal formulation using the KeraskinTM of MCTT, a three-dimensional reconstructed human epidermis. We applied 4 transdermal formulations to the KeraskinTM and after incubation for 6 hr, culture medium was collected. KeraskinTM was washed five times with DPBS and MTT assay was performed for measuring cell viability. The collected medium was analyzed by HPLC-MS/MS to determine the tranexamic acid concentration. Cell viability was calculated through dividing with the absorbance of MTT formazan of AHA/BHA non-containing vehicle group. No significant differences were found in four groups. The concentration of tranexamic acid in culture medium was determined by HPLCMS/MS; 11.0 ± 2.5μg/mL in tranexamic acid in AHA/BHA non-containing formulation, 24.6 ± 3.8μg/mL in tranexamic acid in AHA/BHA containing formulation and not detected in vehicle groups. These findings demonstrated that reconstructed human epidermis can be used for the simultaneous evaluation of the skin permeability and irritancy of transdermal drug and cosmetic ingredients or products.
연구논문 : 인공피부모델을 이용한 트라넥삼산 제형의 피부투과도 및 자극 평가
박양희 ( Yang Hui Park ),장원희 ( Won Hee Jang ),정경미 ( Kyoung Mi Jung ),이수현 ( Su Hyun Lee ),임경민 ( Kyung Min Lim ) 한국동물실험대체법학회 2012 동물실험대체법학회지 Vol.6 No.1
The skin permeability of active ingredient is one of the most important issues for designing transdermal administration form. At the same time, the formulation should be non-irritant to skin. To evaluate skin permeability and irritancy, various methods have been proposed and ex vivo skin is the tool recommended by regulators. However its use is time consuming and requires numerous human donors. Owing to the similarity to real skin, reconstructed human epidermis model have been recognized as a useful tool. We simultaneously evaluated the permeability and irritancy of tranexamic acid in transdermal formulation using the KeraskinTM of MCTT, a three-dimensional reconstructed human epidermis. We applied 4 transdermal formulations to the KeraskinTM and after incubation for 6 hr, culture medium was collected. KeraskinTM was washed five times with DPBS and MTT assay was performed for measuring cell viability. The collected medium was analyzed by HPLC-MS/MS to determine the tranexamic acid concentration. Cell viability was calculated through dividing with the absorbance of MTT formazan of AHA/BHA non-containing vehicle group. No significant differences were found in four groups. The concentration of tranexamic acid in culture medium was determined by HPLCMS/MS; 11.0 ± 2.5μg/mL in tranexamic acid in AHA/BHA non-containing formulation, 24.6 ± 3.8μg/mL in tranexamic acid in AHA/BHA containing formulation and not detected in vehicle groups. These findings demonstrated that reconstructed human epidermis can be used for the simultaneous evaluation of the skin permeability and irritancy of transdermal drug and cosmetic ingredients or products.
SM490A TMC 후판강재의 소재 및 용접부 특성에 관한 연구
김종락,박양희,Kim, Jong Rak,Park, Yang Hee 한국강구조학회 2003 韓國鋼構造學會 論文集 Vol.15 No.3
The study discussed in this paper investigated the material characteristics for the Thermo-Mechanical Control Process(TMCP) plates, which are controlled by several factors such as rolling, cold-stripping, cooling rate, and fixed carbon quantity. The suitability of thick TMCP steel plates as structural steel was also estimated through several experiments and with the us of a statistical method to analyze mill certificate sheets provided by the manufacturer. The results of this study are as follows: the TMCP steel plates showed stable values of the composition parameter ($P_cm$) and the carbon equivalents ($C_eq$ ) with satisfied yield strength, ultimate strength, and low-yield ratio. Thermo Mechanical Control Process(TMCP) 강재는 열간압연시에 압연 온도를 제어하면서 경우에 따라 압연직후 냉각, 열처리하여 안정된 조직으로 압연, 제조된 강재이다. 본 연구에서는 극후판 TMCP강재의 소재특성과 건축구조용 강재로서의 적합성과 특성을 밝히기 위하여 화학성분 및 조직특성, 내력 및 기계적 특성, 사용성 및 인성, 등으로 분류하여 소재특성과 용접특성을 분석하였다. 실험결과, 대상강재는 극후판에서도 설계기준강도를 만족하고 낮은 탄소당량 ($C_{eq}$) 및 용접갈라짐 감수성조성($P_cm$)과 저항복비 등이 확보되었다. 또한, 기준온도(${\pm}0^{\circ}C$)는 물론 $-60^{\circ}C$의 극저온에서도 충분한 충격흡수에너지값으로 양호한 인성의 소재특성을 나타냈고, 용접부에서도 경화현상이 저감되고, 용접부의 인성 및 내력이 충분한 것으로 나타났다.