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      • KCI등재후보

        AMOLED 제조공정에 사용되는 Fine Metal Mask 용 얇은 Invar 합금의 진동자를 이용한 펨토초 레이저 응용 홀 드릴링

        최원석,김훈영,신영관,최준하,장원석,김재구,조성학,최두선,Choi, Won-Suk,Kim, Hoon-Young,Shin, Young-Gwan,Choi, Jun-ha,Chang, Won-Seok,Kim, Jae-Gu,Cho, Sung-Hak,Choi, Doo-Sun 한국금형공학회 2020 한국금형공학회지 Vol.14 No.3

        One of display trends today is development of high pixel density. To get high PPI, a small size of pixel must be developed. RGB pixel is arranged by evaporation process which determines pixel size. Normally, a fine metal mask (FMM; Invar alloy) has been used for evaporation process and it has advantages such as good strength, and low thermal expansion coefficient at low temperature. A FMM has been manufactured by chemical etching which has limitation to controlling the pattern shape and size. One of alternative method for patterning FMM is laser micromachining. Femtosecond laser is normally considered to improve those disadvantages for laser micromachining process due to such short pulse duration. In this paper, a femtosecond laser drilling for thickness of 16 ㎛ FMM is examined. Additionally, we introduce experimental results for controlling taper angle of hole by vibration module adapted in laser system. We used Ti:Sapphire based femtosecond laser with attenuating optics, co-axial illumination, vision system, 3-axis linear stage and vibration module. By controlling vibration amplitude, entrance and exit diameters are controllable. Using vibrating objective lens, we can control taper angle when femtosecond laser hole drilling by moving focusing point. The larger amplitude of vibration we control, the smaller taper angle will be carried out.

      • 극초단 펄스 레이저를 사용한 유리 내부의 필라멘테이션에 대한 실험적 연구

        최원석,윤지욱,김주한,최지연,장원석,김재구,최두선,황경현,조성학,Choi, Won-Suk,Yoon, Ji-Wook,Kim, Joohan,Choi, Jiyeon,Chang, Won-Seok,Kim, Jae-Goo,Choi, Doo-Sun,Whang, Kyoung Hyun,Cho, Sung-Hak 한국레이저가공학회 2013 한국레이저가공학회지 Vol.16 No.1

        We have successfully formed filament inside of a transparent soda-lime glass using a Ti:sapphire based femtosecond laser. To make filament form, keeping the laser intensity higher than critical intensity is essential. Also each of the machining parameters plays an important role for the formation of filament. In this paper, we study what parameter can possibly influence for formation of filament, and we introduce an application using filamentation by femtosecond laser for transparent material.

      • KCI등재

        산소 분압에 따라 전자빔 증착법으로 제작된 TiO<sub>2</sub> 박막의 구조적.광학적 특성

        최원석,김장섭,정종민,한성홍,김의정,이충우,주종현,Choi, Won-Seok,Kim, Jang-Seob,Jung, Jong-Min,Hahn, Sung-Hong,Kim, Eui-Jung,Lee, Chung-Woo,Joo, Jong-Hyun 한국광학회 2007 한국광학회지 Vol.18 No.2

        전자빔 증착법을 이용하여 산소 분압에 따라 $TiO_2$ 박막을 제작하고, 열처리 온도에 따른 박막의 구조적 특성과 광학적 특성을 분석 하였다. $TiO_2$ 박막들의 물리적 특성은 주입된 산소량에 의존하였다. 주입된 산소량이 증가 할수록 상전이 온도가 높아지고, 가시광선 영역에서 $TiO_2$ 박막의 투과율이 증가하였다. 그리고 주입된 산소량이 작은 경우, $700^{\circ}C$에서 $1100^{\circ}C$로 열처리 후 $TiO_2$ 박막의 흡수단 이 좀더 장파장으로 이동하였다. We prepared $TiO_2$ thin films by electron-beam evaporation at various oxygen pressures, and investigated their optical and structural properties as a function of the annealing temperature. The physical properties of the $TiO_2$ thin films depend upon the injection oxygen content. With the increased injection of oxygen, the phase transformation temperature and the transmittance of $TiO_2$ thin films in the range of visible wavelength were increased. For low injection of oxygen, the absorption edges of $TiO_2$ thin films were more red-shifted when annealed at temperatures from $700^{\circ}C$ to $1100^{\circ}C$.

      • KCI등재

        냉동 증편 반죽의 저장 온도 차이에 따른 증편의 품질 특성

        최원석,우경자,Choi Won-Seok,Woo Kyung-Ja 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.4

        The quality of Jeung-pyun made with frozen rice batter was evaluated according to variations in the freezing temperature of the batter. The physicochemical sensory and rheological characteristics of Jeung-pyun were analyzed. The rice batter was stored at -20$^{\circ}C$, -40$^{\circ}C$, and -70$^{\circ}C$ for up to 4 weeks. Statistical data analysis was completed using the SAS program. The pH, and brix percentage of Jeung-pyun batter decreased during the fermentation. In carbon dioxide evolution during fermentation, the levels of the sample stored at -40$^{\circ}C$:, and -70$^{\circ}C$ for 3$\sim$4 weeks were significantly higher than that of the sample stored at -20$^{\circ}C$. The Jeung-pyun moisture content was not significantly affected by freezing temperature or storage times. Specific volume of Jeung-pyun made with rice batter stored at -40$^{\circ}C$, and -70$^{\circ}C$ for 4 weeks was significantly higher than that stored at -20$^{\circ}C$. In sensory evaluation of the stored sample for 4 weeks, the overall quality of Jeung-pyun was not significantly different between with the control and the -20$^{\circ}C$ sample, and between the control and the -40$^{\circ}C$ sample. Among the rheological properties measured with a rheometer on Jeung-pyun made with batter stored sample for 4 weeks at -20$^{\circ}C$, -40$^{\circ}C$ and unfrozen batter, the hardness was increased over the storage time, but the difference was not significant. In conclusion, the most suitable freezing temperature of the rice batter for the manufacture of Jeung-pyun was proposed to be -40$^{\circ}C$.

      • KCI등재

        백혈구 증가증 환아의 혈장내 G-CSF와 GM-CSF의 농도 및 과립구에서의 이들 수용체의 발현

        최원석,유경환,김유정,김소영,김현희,이원배,Choi, Won Seok,Ryu, Kyung Hwan,Kim, You Jeong,Kim, So Young,Kim, Hyun Hee,Lee, Wonbae 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.3

        목 적 : G-CSF와 GM-CSF는 과립구생성에 중요한 사이토카인으로서, 각각의 수용체 G-CSFr과 GM-CSFr에 결합하여 기능을 하게 되며, 이들 수용체들은 미성숙 골수 세포로부터 성숙 된 말초 과립구까지 발현된다. 일반적으로 혈중 G-CSF와 GM-CSF의 농도 및 이들 수용체의 발현은 과립구가 증가하는 감염질환에서 변화한다고 알려져 있으나, 백혈구 증가증에서 과립구수 증가와 관련된 변화에 대해서는 아직 연구된 바가 없다. 본 연구에서는 백혈구 증가증 환아와 정상아의 혈중 G-CSF와 GM-CSF의 농도를 측정하고 말초혈액의 과립구 표면에 존재하는 이들의 수용체를 정량분석하였으며, 활동성이 있는 수용체 발현 양에는 어떤 변화가 있는 지를 분석하여 백혈구 증가증 환아의 과립구 수 증가와 G-CSF와 GM-CSF 및 이들 수용체 변화의 관련성을 규명하고자 하였다. 방 법 : 정상 대조군으로서 비감염성 질환으로 입원한 같은 연령대의 아동 중 말초혈액 백혈구 수 및 중성구 수가 정상인 아동 13명과 급성기 초기의 백혈구 증가증 환아 14명, 총 27명의 혈중 G-CSF와 GM-CSF의 농도를 측정하였고 세포표면 G-CSFr와 GM-CSFr의 발현양은 각각 항 G-CSF 수용체 단 클론항체, 항 GM-CSF 수용체 단클론항체와 혼합 후 유세포 분석기를 이용하여 정량적으로 분석하였으며, 활동성 G-CSFr, GM-CSFr의 양적변화를 유세포 분석기를 이용하여 측정하였다. 결 과 : 백혈구 증가증 환아의 총 백혈구 수는 $24,100{\pm}6960/{\mu}L$로 정상 대조군 $8,680{\pm}378/{\mu}L$에 비해 유의하게 증가되었으며 중성구 수는 백혈구 증가증 환아에서 유의하게 증가되어 있었으나($20,800{\pm}2120/{\mu}L$ vs $3,360{\pm}2,120/{\mu}L$) 단구수는 차이가 없었다. 혈중 G-CSF의 농도 $164.0{\pm}187.5pg/mL$는 정상 대조군 $71.9{\pm}94.1pg/mL$과 감소된 경향을 보였으나 통계적으로 유의한 차이가 없었고(P=0.217) 혈중 GM-CSF의 농도도 유의한 차이가 없었다(P=0.968). 백혈구 증가증 환아의 중성구의 G-CSFr 발현양 $963.6{\pm}575.7$은 정상대조군 $1711.1{\pm}452.6$에 비해 유의한 감소를 보였으며(P=0.012), 백혈구 증가증 환아의 중성구의 GM-CSFr의 발현양 $471.7{\pm}217.0$은 정상 대조군의 $854.8{\pm}383.0$과 통계적으로 유의한 차이가 없었다(P=0.220). 항 G-CSFr항체는 수용체가 G-CSF와 결합하고 나면 수용체에 결합하지 못하는 epitope에 대한 항체로 보여지며, 수용체를 포화시키기에 충분한 과량의 CSF와 배양시킨 후 포화농도에도 결합하지 않은 수용체의 양을 측정하면 남은 수용체 즉, 활동성 수용체 수는 감소하게 되는데, 백혈구 증가증 환아에서 과량의 G-CSF에 배양한 후 감소된 중성구 G-CSFr의 발현양은 $407.8{\pm}405.1$로 정상 대조군의 $1,012.2{\pm}488.5$에 비해 유의한 감소를 보였고(P=0.050), 혈중 G-CSF 농도 및 혈중 GM-CSF 농도와 무관하였다(P=0.735, P=0.087). 백혈구 증가증 환아와 정상대조군에서 수용체를 포화시키기에 충분한 과량의 GM-CSF에 배양한 후 중성구의 GM-CSFr의 발현양을 분석한 결과는 발현이 증가된 소견을 보였다. 증가된 중성구의 GM-CSFr의 발현 양은 정상아 및 백혈구 증가증 환아에서 유의한 차이가 없었다(P=0.828). 결 론 : 백혈구 증가증에서는 중성구 수 증가에 의하여 총 백혈구 수가 증가되고 혈중 G-CSF의 농도는 중성구 증가의 원인으로 생각되며 G-CSFr과 결합하여 백혈구 증가증을 일으키는 것으로 보인다. GM-CSF 농도 및 GM-CSFr은 백혈구 증 Purpose : Granulocyte-colony stimulating factor(G-CSF) and granulocyte macrophage-colony stimulating factor(GM-CSF) are principal cytokines in granulopoiesis and their physiologic effects are mediated through binding to specific cell surface receptors. Although it is known that the level of serum G-CSF and GM-CSF, and presentation of the receptors are increased in infectious diseases, there have been no studies to find the correlation between the granulopoiesis and leukocytosis. This study was designed to measure G-CSF and GM-CSF in leukocytosis and in control and to demonstrate the possible pathogenesis of granulopoiesis in leukocytosis using quantitative analysis of G-CSF, GM-CSF and their CSFr. Methods : The plasma levels of G-CSF, GM-CSF of 13 children without leukocytosis and 14 children with leukocytosis were measured. Counts of cell surface G-CSFr and GM-CSFr were measured by combining anti G-CSFr and anti GM-CSFr monoclonal antibodies to their respective receptors by using quantitative flow cytometric assay. Results : There was no significant difference betweeen the plasma concentration of G-CSF and GM-CSF in acute leukocytosis and in the control group. However, levels of G-CSFr in acute leukocytosis decreased significantly compared to the control(P=0.012) and the levels of GM-CSFr in both groups revealed no significant difference. Conclusion : Increase in the number of leukocyte in leukocytosis was mediated by increasing the number of neutrophil, and increased plasma concentration of G-CSF may be the cause of neutrophilia. But GM-CSF did not have any influence on leukocytosis.

      • KCI등재

        Sensitiv Imago<sup>TM</sup> 측정에 의한 야뇨증 환아의 검사 결과 보고

        최원석,김덕곤,이진용,Choi, Won Seok,Kim, Deog Gon,Lee, Jin Yong 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.4

        Objectives The purpose of this study is to report the nocturnal enuresis in children using Sensitiv $Imago^{TM}$. Methods Twenty nocturnal enuresis children were tested using Sensitiv $Imago^{TM}$. Results 10 cases showed the lowest score at filter $#5^*$ and 7 cases showed the lowest score at filter $6^*$ in {Express Monitoring} of {Review of System Disorders of Homeostasis}. Conclusions Further study with more samples is necessary to establish the accuracy of Sensitiv $Imago^{TM}$.

      • KCI등재

        훈연공정을 첨가하여 제조한 발아콩 청국장의 품질특성

        최원석,박화영,최웅규,Choi, Won-Seok,Park, Hwa-Young,Choi, Ung-Kyu 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.3

        The aim of this study is to investigate the changes in the quality characteristics of cheonggukjang made with germinated soybeans, which is produced by the addition of a smoking process. The L value of smoked cheonggukjang made with germinated soybeans (SCGS) was higher than that of non-smoked cheonggukjang made with non-germinated soybeans (NCNS) and non-smoked cheonggukjang made with germinated soybeans (NCGS). The a value of NCNS was the highest, followed by NCGS and SCGS. The b and ${\Delta}T$ values had a similar tendency compared with the L value. The amino acids in NCGS were significantly decreased compared with NCNS, whereas no remarkable difference in amino acid content was observed between NCGS and SCGS. The moisture content of NCGS ($61.9{\pm}0.9%$) was increased by more than 8% compared with that of NCNS ($53.3{\pm}0.7%$). The moisture content of SCGS was significantly decreased compared with NCGS, whereas the moisture content of SCGS was higher than that of NCNS. The pH of SCGS was significantly the highest, followed by NCGS and NCNS. The viscous substance content of NCGS was significantly increased compared with that of NCNS. No remarkable difference in viscous substance content was observed between NCGS and SCGS. The number of aerobic bacteria in SCGS was significantly decreased compared with NCGS. The levels of total isoflavone in NCNS, NCGS, and SCGS were $1,573.9{\pm}62.5$, $1,759.1{\pm}65.8$, $1,738.0{\pm}68.1mg%$, respectively.

      • KCI등재

        LC 공진형 압력 센서를 이용한 돼지 경골 동맥의 실시간 혈압 측정

        최원석,김진태,정연호,Choi, Won-Seok,Kim, Jin-Tae,Joung, Yeun-Ho 한국전기전자재료학회 2012 전기전자재료학회논문지 Vol.25 No.6

        We have developed an implantable wireless sensor for real time pressure monitoring of blood circulation system. MEMS (micro-electro-mechanical system) technology was adopted as a sensor development method. The sensor is composed of photolithographically patterned inductors and a distributed capacitor in gap between the inductors. A resulting LC resonant system produces its resonant frequency in range of 269 to 284 MHz at 740 mmHg. To read the resonant frequency changed by blood pressure variation, we developed a custom readout system based on a network analyzer functionality. The bench-top testing of the pressure sensors showed good mechanical and electrical functionality. A sensor was implanted into tibial artery of farm pig, and interrogated wirelessly with accurate readings of blood pressure. After 45 days, the sensor's electrical response and histopathology were studied with good frequency reading and biocompatibility.

      • KCI등재

        열처리온도에 따른 다이아몬드상 카본박막의 구조적 특성변화

        최원석,박문기,홍병유,Choi Won-Seok,Park Mun-Gi,Hong Byung-You 한국전기전자재료학회 2006 전기전자재료학회논문지 Vol.19 No.8

        In addition to its similarity to genuine diamond film, diamond-like carbon (DLC) film has many advantages, including its wide band gap and variable refractive index. In this study, DLC films were prepared by the RF PECVD (Plasma Enhanced Chemical Vapor Deposition) method on silicon substrates using methane $(CH_4)$ and hydrogen $(H_2)$ gas. We examined the effects of the post annealing temperature on the structural variation of the DLC films. The films were annealed at temperatures ranging from 300 to $900^{\circ}C$ in steps of $200^{\circ}C$ using RTA equipment in nitrogen ambient. The thickness of the film and interface between film and substrate were observed by surface profiler, field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM), respectively. Raman and X-ray photoelectron spectroscopy (XPS) analysis showed that DLC films were graphitized ($I_D/I_G$, G-peak position and $sp^2/sp^3$ increased) ratio at higher annealing temperature. The variation of surface as a function of annealing treatment was verified by a AFM and contact angle method.

      • KCI등재

        그리드 네트워크에서 종단간 전송 지연 향상을 위한 bottleneck 링크 대역폭 측정 알고리즘

        최원석,안성진,정진욱,Choi, Won-Seok,Ahn, Seong-Jin,Chung, Jin-Wook 한국정보처리학회 2003 정보처리학회논문지 C : 정보통신,정보보안 Vol.10 No.7

        본 논문은 그리드 네트워크의 패킷 지연시간단축을 위한 병목 링크 대역폭 측정 알고리즘을 제안하고자 한다. 병목 링크 대역폭 측정방법으로 packet pair 알고리즘과 Paced Probes가 있으나 이들은 pacer 패킷으로 cross traffic의 영향을 줄이면서 Paced probe 패킷들이 링크를 지날 때 발생하는 시간 차이를 이용하여 병목 링크 대역폭을 구한다. 그러나 경로상의 병목 링크 대역폭을 측정할 뿐이지 병목현상이 발생한 지점은 알 수 없는 문제점이 있다. 이를 hop-by-hop 측정에 기반한 병목 대역폭 측정을 제시하여 그리드 네트워크에서 전체적인 패킷 지연 개선을 이룰 수 있다. hop-by-hop의 병목 대역폭을 측정하기 위해 paced probe 패킷에 타임스탬프 옵션을 이용하며 병목현상 해소를 통하여 패킷 전송 지연의 단축을 시뮬레이션을 통해 알 수 있다. 본 논문에서 제시한 알고리즘으로 병목 링크의 대역폭과 위치를 파악하여 그리드 ETP나 실시간 QoS를 보장하는 데이터 전송에 기여할 것으로 기대된다. This paper proposes a bottleneck link bandwidth measurement algorithm for reducing packet transmission delay within the grid network. There are two methods for measuring bottleneck link bandwidth:Packet Pair algorithm and Paced Probes algorithm. They measure bottleneck link bandwidth using the difference in arrival times of two paced probe packets of the same size traveling from the same source to destination. In addition, they reduce the influences of cross traffic by pacer packet. But there are some problems on these algorithms:it's not possible to know where bottleneck link occurred because they only focus on measuring the smallest link bandwidth along the path without considering bandwidth of every link on the path. So hop-by-hop based bottleneck link bandwidth measurement algorithm can be used for reducing packet transmission delay on grid network. Timestamp option was used on the paced probe packet for the link level measurement of bottleneck bandwidth. And the reducing of packet transmission delay was simulated by the solving a bottleneck link. The algorithm suggested in this paper can contribute to data transmission ensuring FTP and realtime QoS by detecting bandwidth and the location where bottleneck link occurred.

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