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보문 : 버섯 세균성갈색무늬병원균(Pseudomonas tolaasii)의 분비 독소(tolaasin)를 저해하는 미생물 Pseudomonas sp. HC1
이찬중 ( Chan Jung Lee ),유영미 ( Young Mi Yoo ),한주연 ( Ju Yeon Han ),전창성 ( Chang Sung Jhune ),정종천 ( Jong Chun Cheong ),문지원 ( Ji Won Moon ),서장선 ( Jang Sun Suh ),한혜수 ( Hye Su Han1 ),차재순 ( Jae Soon Cha ) 한국균학회 2013 韓國菌學會誌 Vol.41 No.4
A Gram-negative bacterium was isolated from mushroom media that markedly reduces the level of extracellular toxins (i.e., tolaasins) produced by Pseudomonas tolaasii, the most destructive pathogen of cultivated mushrooms. The HC1 strain was selected as detoxifying tolaasin by bioassay on potato and it was identified Pseudomonas sp. by the cultural, morphological and physiological characteristics, and analysis of the 16S rRNA.. The isolated bacterium is saprophytic but not parasitic nor pathogenic to cultivation mushroom. The isolated bacterium for P. tolaasii cell, was sufficient for detoxification in vitro. Inoculation of the isolated bacterium prevents the development of bacterial disease in Pleurotus ostreatus, Flammunia velutipes and Agaricus bisporus. Control efficacy of brown blotch of strain HC1 treatment was 69, 68 and 55% on Agaricus bisporus, Flammulina velutipes and Pleurotus ostreatus, respectively. The suppressive bacterium may be useful in future for the development of biocontrol system and the construction of genetically modified edible fungi resistant to the disease caused by P. tolaasii.
보문 : 버섯 세균갈색무늬병균(Pseudomonas tolaasii)에 항균활 성을 가지는 미생물 Pseudomonas azotoformans HC5
이찬중 ( Chan Jung Lee ),유영미 ( Young Mi Yoo ),한주연 ( Ju Yeon Han ),전창성 ( Chang Sung Jhune ),정종천 ( Jong Chun Cheong ),문지원 ( Ji Won Moon ),공원식,서장선 ( Jang Sun Suh ),한혜수 ( Hye Su Han ),차재순 ( Jae Soon Cha ) 한국균학회 2014 韓國菌學會誌 Vol.42 No.3
A gram-negative bacterium was isolated from spent substrate of Agaricus bisporus and showed marked antagonistic activity against Pseudomonas tolaasii. The bacterium was identified as Pseudomonas azotoformans by based on the cultural, biochemical and physiological characteristics, and 16S rRNA gene sequence. The isolated bacterium was saprophytic but not parasitic nor pathogenic to cultivation mushroom. The isolated bacterium for P. tolaasii cell was not sufficient for inhibition in vitro. Control efficacy of Pseudomonas azotoformans HC5 to brown blotch of P. tolaasii was 73, 78, and 71% on A. bisporus, Flammulina velutipes, and Pleurotus ostreatus, respectively. In the future, the suppressive bacterium may be useful for development of a biocontrol system.
Yoo, Su-Min Cho, Ja-Won Hwang, Kyung-Sook Kim, Chan-Ho Chae, Sang-Kun, Sung, Young-Eun Lee, John-Hwa International Journal of Clinical Preventive Denti 2011 International Journal of Clinical Preventive Denti Vol.7 No.1
Objective: The aim of this study was to ascertain the effects on oral environment improvement including the control of dental plaque, the prevention of gingivitis and the repression of oral malodor using dentifrice mixed with hydrated silica, sodium monofluorophosphate, green tea extract and cetylpyridinium chloride. Methods: The experiment was conducted of 95 of Korean male and female adult volunteers using by double blind method. Before the experiment started, the subjects removed their tartar mechanically to make the oral conditions of all subjects same. After 2 weeks for no residual effect, the oral environmental index was measured as baseline value. For 3 months, the subjects were instructed to use dentifrice experimented and the effect of hydrated silica, sodium monofluorophosphate, green tea extract and cetylpyridinium chloride was analyzed comparing experiment group 1 and 2 with control group. Results: The changes of gingivitis and plaque index of 2 experiment groups, which is to figure out the improvement of gingivitis, were significantly different compared to that of control group (p<0.05). Changes of oral malodor of 2 experiment groups were significantly different compared to that of control group (p<0.05). After 3 months freshness of 2experiment groups were significantly different compared to that of control group (p<0.05). The experiment group had freshness at about 7.83, experiment group 1 at about 7.97 while the control group at about 3.15. Conclusion: The most effective improvement especially shown on the oral conditions were dentifrice that contains.
최수정,김영석,김나리,정승원,이선해,정준성,류권호,차상우,홍수진,유창범,문종호,김연수,이문성,심찬섭,김부성,권계원,김병용 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.4
Hepatocellular carcinoma is one of the most common causes of death in Koreans. Most cases of hepatocellular carcinoma are beyond the stage of curative resection at the time of diagnosis due to extrahepatic metastasis as well as wide distribution of tumor in the liver. The lung is the most common site of extrahepatic metastasis but metastasis to gingiva is very rare in hepatocellular carcinoma. We report a case hepatecellular carcinoma with gingival methststasis in a 59 year old male patient.(Korean J Hepatol 2002;8:495-499)