갑상선 결절의 감별진단에 있어 탄성 초음파검사

김정훈,최재영,최영식<SUP>1<,SUP>,정미희<SUP>2<,SUP>,정경순<SUP>2<,SUP>,Jung Hoon Kim,M,D,Jae Young Choi,M,D,Young Sik Choi,M,D,<SUP>1<,SUP>,Mi Hee Jung,M,D,<SUP>2<,SUP> and Kyung Soon Jung,M,D,<SUP>2<,SUP> 대한갑상선-내분비외과학회 2011 The Koreran journal of Endocrine Surgery Vol.11 No.1

Purpose: Ultrasound (US) elastography is a newly developed imaging technique for assessing tissue stiffness by measuring the degree of the tissue's deformation in response to the application of an external force. This technique has recently been applied for making the diagnosis of nodular thyroid disease. The purpose of this study was to evaluate the diagnostic utility of US elastography for differentiating benign thyroid nodules from malignant thyroid nodules. Methods: A total of 63 consecutive patients with thyroid nodules and who were referred for surgical treatment were examined in this study. Seventy-five nodules in these patients were examined by US B-mode, color Doppler US and US elastography. The final diagnosis was obtained from the histologic findings. The tissue stiffness on ultrasound elastography was scored from 1 (elasticity in the whole nodule) to 5 (no elasticity in the nodule and in the posterior shadowing). Results: On US elastography, 18 of 32 benign nodules (56.3%) had a score of 1 to 3, whereas 23 of 43 malignant nodules (62.8%) had a score of 4 to 5. With applying a US elastography score of 4-5 as an indicator for malignancy, the sensitivity, specificity, positive predictive value and negative predictive value of US elastography were 65.9%, 52.9%, 62.8% and 56.3%, respectively. Of the 14 follicular tumors, 12 were follicular adenoma and four were follicular carcinoma. The sensitivity and specificity of US elastography for diagnosing follicular carcinoma were 50.0% and 81% (56=69), respectively. The positive and negative predictive values were 55.2% (16=29) and 60.0%, respectively. The accuracy of the technique was 57.1%. The findings of US elastography were not significantly correlated with the histopathologic findings. Conclusion: This study has shown that US elastography may be not useful for differentiating between benign and malignant thyroid nodules. Further studies are needed to confirm the usefulness of US elastography for making the differential diagnosis of thyroid nodules. (Korean J Endocrine Surg 2011;11:12-17)

유료 콘텐츠의 N-스크린 서비스를 위한 일시적 시청권한 위임 기법

김정훈,이훈정,김상진,오희국,Kim, Jung-Hoon,Lee, Hoon-Jung,Kim, Sang-Jin,Oh, Hee-Kuck 한국정보처리학회 2011 정보처리학회논문지 C : 정보통신,정보보안 Vol.18 No.3

최근, 통신기술의 급속한 발전으로 인해 때와 장소에 구애받지 않고 콘텐츠를 소비하고자 하는 사용자의 욕구와 새로운 비즈니스 모델을 찾고자 하는 사업자의 바람이 맞물려 N-스크린 서비스 전략이 주목 받고 있다. N-스크린은 TV, 컴퓨터, 휴대용 단말 등 다양한 기기에서 끊김 없이 콘텐츠를 공유, 소비할 수 있도록 지원하는 스크린 확장 개념의 서비스로서 미국의 통신회사인 AT&T에서 처음 제안했던 3-스크린 서비스 전략이 발전된 형태이다. 유료 콘텐츠에 대한 N-스크린 서비스에서 유료 콘텐츠에 대한 끊김없는 스크린 전환을 지원하기 위해서는 스크린을 전환하고자 하는 기기로 일시적인 시청권한을 부여해야 한다. 하지만 접근제어 시스템을 사용하고 있는 현재의 방송환경에서는 일시적으로 권한을 부여하는 것이 불가능하다. 본 논문에서는 현재 방송환경에서 유료콘텐츠에 사용하고 있는 접근제어 기법에 대해 살펴보고 일시적인 권한 부여를 할 수 없는 이유에 대해서 살펴본 뒤 현재 사용 중인 접근제어 기법을 기반으로 추가적인 키를 사용해 시청권한 문제를 해결하는 방법을 제안한다. Recently, the strategy for N-screen service is in the spotlight along with the consumer's need to use contents regardless of time and place due to the rapid development of communication technology, which is meshing with the desire of service providers seeking a new business model. N-screen, as a screen-extension-concept service which enables consumers to continuously share and use contents in various equipments such as TV, computer and portable terminals, is an advanced type of 3-screen service strategy initially proposed by AT&T, an American telecommunication company. In the N-screen service for pay-contents, in order to support continuous screen changes to and from various equipments, temporary watching right should be given to the equipment intended for screen change. However, it is impossible to give the temporary watching right in the present broadcasting environment, adopting an access-control system. In this paper, the access-control technology being used for pay-contents in the present broadcasting environment and the reason for not being able to give temporary watching right, will be examined. After the examination, the solution for delegation of watching right by using an additional key on the basis of currently used access-control technology, will be proposed.

Recurrence and Extraneural Metastasis in 31 Meningeal Hemangiopericytomas

김정훈,김준수,김창진,황승균,정희원,권병덕,Kim, Jeong Hoon,Kim, Joon Soo,Kim, Chang Jin,Hwang, Sung Kyun,Jung, Hee Won,Kwun, Byung Duk The Korean Neurosurgical Society 2001 Journal of Korean neurosurgical society Vol.30 No.3

목 적 : 높은 재발율과 전이 가능성의 특징을 갖고 있는 수막 혈관외세포종은 perivascular pericytes에서 기원하는 드문 종양으로, 저자들이 경험한 수막 혈관외세포종에 있어서 종양의 재발 및 신경계외 전이에 대하여 알아 보고자 한다. 연구 대상 및 방법 : 1982년부터 1999년까지 수술을 시행하여 수막 혈관외세포종으로 진단받은 31명의 환자를 대상으로 후향적 연구를 시행하였다. 진단 후 재발까지의 기간, 재발에 영향을 미칠 수 있는 여러 가지 인자들, 그리고 신경계외 전이의 기간 및 부위 등을 분석하였다. 결 과 : 총 31명의 환자들 중 12명의 환자들에서 원발성 부위에 종양이 재발하였다(38.7%). 전체의 환자들에서 재발이 발생하지 않았던 평균 기간(recurrence-free period : RFP)은 104개월이었으며 처음 수술 후 5년, 그리고 10년의 재발이 발생하지 않았던 율(recurrence free period : RFP)은 각각 59.2%, 33.6% 이었다. 원발성 부위에 종양의 재발을 보였던 12명의 환자들 중 4명의 환자들에서 첫 수술 후 5년 이후에 재발을 관찰 할 수 있었다. 처음 수술시의 절제 정도가 재발에 가장 큰 영향을 미쳤다. 처음 수술시에 완전 절제한 군의 RFP는 111 개월이었으며, 추적 관찰 5년째 RFR는 완전 절제한 경우 72.7%, 불완전 절제한 경우 20.8%로 그 차이는 통계 적으로 유의하였다(p=0.0060). 통계적으로 유의성은 없었지만 완전 절제 후 부가적인 방사선 치료를 시행하였을 경우가 완전 절제만을 시행한 경우보다 RFR가 높아 추적 관찰 5년째의 RFR는 각각 100%, 그리고 70.3% 이었다(p=0.3359). 4명의 환자들(12.9%)에서 수막 혈관외세포종의 신경계외 전이가 발생하였으며, 이 경우 신경계 외 전이의 평균 기간은 107개월, 그리고 추적 관찰 5년, 10년째의 신경계외 전이율은 각각 4.4%, 24.9% 이었다. 결 론 : 수막 혈관외세포종은 수술적 제거 후 원발성 부위에 또는 원발성 부위에서 멀리 떨어진 부위에 재발의 가능성이 무척 높은 종양이다. 이러한 재발의 가능성을 줄이는 가장 중요한 인자는 수술적 제거 정도로 처음 수술시에 가능한 완전 절제를 시도하여야 한다. 그리고 처음 수술시에 완전 절제가 가능하였다고 하여도 완전 절제 후 부가적인 방사선 치료를 시행하는 것이 재발의 위험성을 낮출 수 있을 것으로 생각한다. 원발성 부위의 재발 또는 신경계외 전이는 오랜 시간이 지난 후에도 가능할 수 있으므로 장기간의 추적 관찰이 필요하다고 생각한다. Purpose : Meningeal hemangiopericytoma(M-HPC), characterized by a high local recurrency and metastatic potential, is a rare neoplasm arising from perivascular pericytes. A retrospective study was performed to identify the recurrence and extraneural metastasis in M-HPC. Materials and Methods : We reviewed the records of 31 M-HPC patients treated from 1982 through 1999 at our institution. The time to recurrence and the various parameters affecting recurrence were determined. Extreneural metastasis was also analyzed. Results : The rate of local recurrency was 38.7%(12/31). The overall average recurrence-free period(RFP) before the first recurrence was 104 months, with overall recurrence-free rates(RFRs) at 5 and 10 years after first surgery of 59.2% and 33.6%, respectively. Of the 12 patients who experienced local recurrence, 4 had recurrences 5 years later after the first surgery. Complete excision at the first operation significantly extended the average time before first recurrence from 43 to 111 months. The 5-year RFRs for the groups of complete excision and incomplete excision were 72.7% and 20.8%, respectively(p=0.0060). Although there was no statistical significance, complete excision followed by adjuvant radiotherapy of more than 50Gy extended the RFP. The 5-year RFRs for the groups of complete excision and complete excision with adjuvant radiotherapy were 70.3% and 100%, respectively(p=0.3359). Four patients(12.9%) presented one or more extraneural metastases that were developed at an average of 107 months after the first operation with the 5- and 10-year metastasis rates of 4.4% and 24.9%, respectively. Conclusions : M-HPC has a propensity to recur either locally or at distant sites after surgical resection. Complete excision is the most important factor to reduce recurrence. However, even with complete excision, adjuvant radiotherapy of more than 50Gy significantly reduces the risk of recurrence. Local and distant recurrences may occur after a prolonged disease-free interval, emphasizing the need for long-term follow-up.

취업 주부의 취업선호 인식이 개인 , 가족 직업생활에 미치는 영향

김정훈,박성옥,어은주 ( Jung Hoon Kim,Sung Ok Park,Eun Joo Eo ) 대한가정학회 1996 Human Ecology Research(HER) Vol.34 No.3

전탕 방법 및 전탕 시간에 따른 육미지황탕 전탕액 비교 연구

김정훈,서창섭,전우영,신현규,Kim, Jung-Hoon,Seo, Chang-Seob,Jeon, Woo-Young,Shin, Hyeun-Kyoo 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.1

Objectives : This study was performed to compare the differences between decoctions extracted by different extraction method and extraction time. Methods : Decoctions were prepared with pressed or non-pressed extraction conditions for 60, 120 and 180min. The yields of extracts, sugar contents, hydrogen ion concentrations(pH), the contents of reference compounds in Yukmijihwang-tang(Liuweidihuang-tang) were investigated. Results : The yields and the dissolved solid content containing sugar content of decoctions were more in pressed extraction method than unpressed extraction method, and they tended to be increased as extraction time increased. The pH values of decoctions methods did not show significant differences between pressed and unpressed extraction methods or extraction times. Most of reference compounds showed higher contents in pressed extraction method than unpressed extraction method and their contents were augmented according to increase of extraction time. The content of paeonol was decreased when extracted in more than 120min with pressed extraction method and tended to be decreased as extraction time increased in unpressed extraction method. Conclusions : The pressed extraction with long extraction time could be useful for decoction of Yukmijihwang-tang(Liuweidihuang-tang). However, another ingredients possible to decrease in such condition need to be considered to determine suitable extraction condition.

열보호재료의 열 및 물질전달 현상에 관한 수치해석적 연구

김정훈,권창오,서정일,배철호,송동주,Kim, Jung-Hoon,Kwon, Chang-Oh,Seo, Jeong-Il,Bai, Cheol-Ho,Song, Dong-Joo 대한기계학회 1999 大韓機械學會論文集B Vol.23 No.9

A numerical analysis is performed to predict the thermal response and ablation rate for charring or non-charring material which is designed to be used as thermal protection system (TPS). The numerical program composed of in-depth energy balance equation and the aerotherm chemical equilibrium (ACE) program. The ACE program calculates various thermochemical state from ablation products. The developed numerical program is verified by comparing the reported results from literature. The sensitivity tests for input parameters are performed. The thermal behavior of ablating material is mainly affected by density of ablating material, convective heat transfer coefficient and recovery enthalpy of flow field.

보중익기탕(補中益氣湯)이 생쥐의 기아(飢餓)stress에 미치는 영향

김정훈,이태희,Kim, Jung-Hoon,Lee, Tae-Hee 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.1

Objectives: We investigated the effect of Bojungikgitang on the change of the corticosterone and the rectal temperature of the mice induced by starvation stress. Methods: After administration of Bojungikgitang three times, mice were starved. The corticosterone and rectal temperature were measured after 36.5 hours starvation stress. Results : The plasma corticosterone level in Bojungikgitang(0.25g/Kg) was decreased comparing with the Control group and the rectal temperature in the Bojungikgitang(1.0g/Kg) was increased comparing with the Control group. Conclusion : it might be recognized that Bojungikgitang has anti starvation stress effect, and also it might be needed further study in various viewpoints.

유비쿼터스 시대를 대비한 u-City 계획체계 정립방안

김정훈,조춘만,Kim, Jung-Hoon,Cho, Chun-Man 한국공간정보학회 2008 한국공간정보학회지 Vol.16 No.1

2008년 2월 $\ulcorner$유비쿼터스도시의건설등에관한법률$\lrcorner$이 국회를 통과하였다. 이 법에는 유비쿼터스도시 계획, 건설, 관리에 관한 사항들이 정해져 있다. 범국가 차원의 법 추진체계가 마련됨에 따라 향후 도시들이 u-City로 계획되고 건설될 수 있는 법적 근거를 가지게 된다. 앞으로 이 법률에 근거하여 국가차원의 u-City 종합계획 등 계획적 수요가 크게 증대할 것으로 기대된다. 본 연구는 이러한 새로운 수요에 대응하기 위해 u-City를 실제 구현하고 현실화하기 위한 수단으로 계획적 접근방법을 찾아보고자 수행되었다. 저마다 다른 내용과 범위를 가지고 난립하고 있는 u-City 사업을 보다 구조화되고 체계화된 관점에서 수립되도록 규정하기 위한 틀을 제공하고자 하였다. 이에 본 연구는 u-City 구현을 위한 종합적인 계획체계의 틀을 정립하는데 목적을 두고 u-City 계획과 관련된 이론적 근거를 살펴보고 기존 u-City관련 사례 및 관련 계획을 분석하고 이를 바탕으로 u-City 계획체계의 개념, 특성, 구성요소를 정립하였다. Last February, $\ulcorner$The Act on Ubiquitous City Construction and etc.$\lrcorner$ was approved by the National Assembly. The law stipulates the regulations on the planning, construction and management of the Ubiquitous City. As its national-level law system is about to take its effects, future new city developments are expected to have its legal basis to be built to meet ubiquitous city requirements. Also, it is anticipated that such needs would require much more planning techniques and strategies. In reaction to those upcoming needs, this study is to search for new planning approaches to realize the u-City in reality. It is also to supply with the framework to execute the u-City projects in more structuralize and systemize manner. Therefore, with the purpose of the establishment of comprehensive planning system, the theoretical bases were sought in relation to planning u-City, pre-existing u-City development cases and regarding regulations were analyzed, and then basic concepts, features, and constituent factors were set up.

u-City 구현을 위한 현안과제 조사분석

김정훈,이미숙,Kim, Jung-Hoon,Yi, Mi-Sook 한국공간정보학회 2007 한국공간정보학회지 Vol.15 No.1

최근 'u-City'라는 명제 하에 도시민의 일상적인 삶의 토대로서의 물리적 도시환경과 첨단정보기술의 통합이 본격적으로 시도되고 있다. 이에 따라 u-City의 효용성과 파급효과에 대한 기대심리와 u-City 구현의 걸림돌이 되는 다양한 법제도 및 기술적 제약요인들로 인한 우려의 목소리가 공존하고 있다. 이에 본 연구는 u-City의 성공적인 구현을 위해 시급히 해결해야 할 현안과제를 도출하고 시사점을 제시함으로써, u-City 구현에 대한 회의적이고 부정적인 시각을 해소해나가고자 한다. 이러한 취지에서 이 연구에서는 u-City구현과 관련된 각계 각층의 전문가들의 의견을 수렴하여 u-City구현을 위한 u-인프라, u-서비스, 정책(법제도)측면의 현안과제와 u-City의 추진단계별 현안 과제를 도출하고 시사점을 제시하였다. u-City is a new concept and phenomena of applying Information & Communications Technology(ICT) into real cities in Korea. In order to effectively integrate a city with high-tech ICT infrastructure, cutting-edge ICT is being integrated into physical urban environments from the planning and construction stage of a city. There are positive expectations regarding its effect on urban planning and citizens' lives. However, construction of u-city has technical limitations as well as institutional obstacles. This paper aims at identifying problems of current u-city practices and suggesting appropriate solutions for those problems. To do so, it first collects opinions from diverse experts. Then, it draws problems and suggests solutions in terms of u-infrastructure, u-service, policy and implementation process.

『성제총록(聖濟總錄)』과 『동의보감(東醫寶鑑)』의 침향 배오 처방 비교 연구

김정훈,김현정,박민주,이장천,이부균,Kim, Jeong-Hoon,Kim, Hyun-Jung,Park, Min-Joo,Lee, Jang-Cheon,Lee, Boo-Kyun 대한한의학방제학회 2019 大韓韓醫學方劑學會誌 Vol.27 No.1

Objectives : In spite of the difficulty of getting Agarwood, the number of species of wild Agarwood is rapidly decreasing by insistent demands. Here, we investigate how various formula of Agarwood is used so that we can make use of them more helpful in clinics today. Methods : Determining the range of 'the Sovereign and Minister' component more than 12.96%" or 'equally used', this study distinguished whether Agarwood is used as 'the Sovereign and Minister' component among 409 Agarwood formulas in "Sheng ji zong lu(聖濟總錄)" and 103 Agarwood formulas in "Donguibogam (東醫寶鑑)". Additionally, we analyzed the component ratio of Agarwood, and also the usage in Deficiency-Excess pattern. Results : Among Agarwood formulas in "Sheng ji zong lu" and "Donguibogam", each percentage of Agarwood formulas which Agarwood comprises 'the Sovereign and Minister' component was 26%(106/406) and 13%(13/99). Analyzing these formulas of "Sheng ji zong lu", 53 formulas were used in Deficiency pattern and other 53 formulas were used in Excess pattern. Also in "Donguibogam", 6 formulas were used in each Deficiency pattern and Excess pattern, and only 1 formula in both of Deficiency and Excess pattern. Conclusions : Showing almost equal ratio of usage in Deficiency-Excess pattern, this study showed that those Agarwood formulas of "Sheng ji zong lu" and "Donguibogam" which Agarwood comprises 'the Sovereign and Minister' component can be used in both Deficiency-Excess pattern evenly.