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Jung, W. H.,Kang, D.‐,H.,Han, J. Y.,Jang, J. H.,Gu, B.‐,M.,Choi, J.‐,S.,Jung, M. H.,Choi, C.‐,H.,Kwon, J. S. Blackwell Publishing Ltd 2011 Acta psychiatrica Scandinavica Vol.123 No.5
<P>Jung WH, Kang D‐H, Han JY, Jang JH, Gu B‐M, Choi J‐S, Jung MH, Choi C‐H, Kwon JS. Aberrant ventral striatal responses during incentive processing in unmedicated patients with obsessive–compulsive disorder.</P><P><B>Objective: </B> Obsessive–compulsive disorder (OCD) is characterized by the dysfunction of control and reward mechanisms. However, only few neuroimaging studies of OCD have examined the reward processing. We examined the neural responses during incentive processing in OCD.</P><P><B>Method: </B> Twenty unmedicated patients with OCD and 20 age‐, sex‐, and IQ‐matched healthy controls underwent functional magnetic resonance imaging while performing a modified monetary incentive delay task.</P><P><B>Results: </B> Compared with controls, patients with OCD showed increased ventral striatal activation in the no‐loss minus loss outcome contrast and a significant positive correlation between the ventral striatal activation and compulsion symptom severity. In addition, patients with OCD showed increased activations in the frontostriatal regions in the gain minus no‐gain outcomes contrast. During loss anticipation, patients with OCD showed less activations in the lateral prefrontal and inferior parietal cortices. However, during gain anticipation, patients with OCD and healthy controls did not differ in the ventral striatal activation.</P><P><B>Conclusion: </B> These findings provide neural evidence for altered incentive processing in unmedicated patients with OCD, suggesting an elevated sensitivity to negatively affect stimuli as well as dysfunction of the ventral striatum.</P>
Enhancement of Rice Resistance to Bacterial Blight by Overexpressing BrCP3 Gene of Brassica rapa
( Marjohn C. Nino ),( Hye Jung Lee ),( Joonki Kim ),( Sailila E. Abdula ),( Yu Jin Jung ),( Kwon Kyoo Kang ),( Illsup Nou ),( Yong Gu Cho ) 한국육종학회 2015 Plant Breeding and Biotechnology Vol.3 No.4
Brassica rapa cysteine protease 3 (BrCP3) is an endopeptidase member of C1A family (papain-like) and CA clan of cysteine protease. Members of papain-like cysteine protease (CP) have emerged to be key enzymes involved in cell death in response to biotic and environmental stresses. Recent progress of CP research features its diverse and overlapping role in basal and effector-triggered immunity. This study was carried out to characterize BrCP3 gene in Chinese cabbage and explore its function in rice - Xanthomonas oryzae pv. oryzae pathosystem. Phylogenetic analysis and BLASTP search of its amino acid sequence to the Arabidopsis Protein TAIR 10 database identified BrCP3 as the closest ortholog of Arabidopsis RD21a. The full-length cDNA of BrCP3 was cloned and transformed into the genome of japonica rice cv. ‘Gopum’. Constitutive overexpression of the transgene is driven by Ubi-1 promoter in pFLCIII vector. Regenerated single copy overexpression rice lines were inoculated with three Xoo Korean isolates. Regulation of rice resistance through cysteine protease activity is evident in the overexpression lines which showed enhanced immunity to three isolates as depicted by reduced lesion length compared with the wild type. Our initial results implicate an interesting biological function of BrCP3 in rice system that has never been reported before.
Gu-Ho Jung(정구호),Kyung-Hun Lee(이경훈),Hyung-Guk Kim(김형국),Yang-Jin Cho(조양진),Bo-Yun Song(송보윤),Young-Dong Son(손영동),Eun-Ha Park(박은하),Ju-Young Choi(최주영),Byung O Kong(공병오),Jin Huh(허진),Ho-Sub Son(손호섭),Jung-Gu C 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.7
온라인 전기자동차는 도로에 매설된 급전선로로부터 유도자계를 통하여 비접촉 방식으로 전기를 집전 받아 정차 및 주행 중에 충전하는 자동차이다. 이러한 비접촉 충전을 위해서는 도로에 매설된 급전 시스템과 차량 하부에 장착된 집전 시스템이 필요하며, 급전 시스템은 다시 급전 인버터와 급전선로로, 집전 시스템은 집전 모듈(pick-up)과 집전 레귤레이터로 구성된다. 본 논문에서는 급집전 시스템 각각의 장치를 소개하며, 더불어 구축된 시스템의 성능에 대해서도 소개한다.
( C. Young Lee ),( Jung Won Lim ),( Young Hyun Ko ),( Sun Young Kang ),( Man Jong Park ),( Tae Gu Ko ),( Ji Hoon Lee ),( Young Hyum ),( Kyu Sik Jeong ),( In Surk Jang ) 한국동물자원과학회(구 한국축산학회) 2011 한국축산학회지 Vol.53 No.3
A total of 96 crossbred weanling barrows aged 21 days were randomly allocated to 32 pens of a new nursery to investigate the effects of antibiotics, phytogenics, and probiotics on intestinal growth and development. The animals were fed a set of three-phase basal diets containing 0.3% zinc oxide(CON) or the basal diets supplemented with 353 ppm of a combination of tiamulin, neomycin, chlortetracycline, and oxytetracycline(ANTI), 75 ppm triterpenoid saponin plus 150 ppm mixed saccharides (HERB; Sacchapin(R)), or 1×107 brewer`s yeasts plus 8×107 spores of each of Bacillus licheniformis and Bacillus subtilis per kilogram feed (PROBIO; Yeasture Plus 2B(R)) for five weeks. Thirty-two pigs representing as many pens were slaughtered at the end of the feeding trial, after which morphological measures and digestive enzyme activities of intestinal mucosa were determined. Weight gain and gain:feed of the pigs were not affected by the dietary treatments(TRT) during the overall feeding trial. Total intestinal length was greater in PROBIO than in ANTI(P<0.05). Wet mucosa weight of the duodenum was not affected by TRT. However, jejunal mucosa weight was greater in PROBIO than in any other group sum of mucosa weights of the duodenum and jejunum was greater(P<0.05) in PROBIO than in ANTI and HERB. The height and width of duodenal villus were not affected by TRT, but crypt depth decreased(P<0.05) in response to HERB and PROBIO vs CON. Specific activities of alkaline phosphatase, sucrase, maltase, lactase, and leucine aminopeptidase in the duodenum and jejunum were not changed by TRT. In conclusion, results suggest that the present dietary treatments have no effects on growth performance of weanling pigs and that of PROBIO enhances intestinal growth and development under a clean experimental setting.
Overexpression of UGE1 from Brassica rapa enhances yield and tolerance to drought in transgenic rice
Hye Jung Lee,Sailila E. Abdula,Marjohn C. Niño,Kwon-Kyoo Kang,Illsup Nou,Yong-Gu Cho 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07
UDP-glucose 4-epimerase (UGE) catalyzes the reversible conversion of UDP-glucose to UDP-galactose. To understand the biological function of UGE from Brassica rapa, the gene hereinafter referred to as was cloned and overexpressed into Japonica rice cv. Gopum. Transcriptional profiling showed that the is specific to stem of rice plant. Morphological evaluation of the overexpression lines revealed altered phenotype characters particularly in panicle length, number of productive tillers and filled spikelets which account for an increase in yield. This remarkable agronomic performance was ascribed to higher photosynthetic rate complemented with higher CO2 assimilation. Interestingly, BrUGE1 did not only improve plant fitness under optimal condition but also under water deficit stress. The enhanced drought tolerance may be due to the induction of soluble sugar which may act as osmolyte to compensate dehydration during drought stress.
Lee, C.-Young,Lim, Jung-Won,Ko, Young-Hyun,Kang, Sun-Young,Park, Man-Jong,Ko, Tae-Gu,Lee, Ji-Hoon,Hyun, Young,Jeong, Kyu-Sik,Jang, In-Surk Korean Society of Animal Sciences and Technology 2011 한국축산학회지 Vol.53 No.3
A total of 96 crossbred weanling barrows aged 21 days were randomly allocated to 32 pens of a new nursery to investigate the effects of antibiotics, phytogenics, and probiotics on intestinal growth and development. The animals were fed a set of three-phase basal diets containing 0.3% zinc oxide (CON) or the basal diets supplemented with 353 ppm of a combination of tiamulin, neomycin, chlortetracycline, and oxytetracycline (ANTI), 75 ppm triterpenoid saponin plus 150 ppm mixed saccharides (HERB; Sacchapin$^{(R)}$), or $1{\times}10^7$ brewer's yeasts plus $8{\times}10^7$ spores of each of Bacillus licheniformis and Bacillus subtilis per kilogram feed (PROBIO; Yeasture Plus 2B$^{(R)}$) for five weeks. Thirty-two pigs representing as many pens were slaughtered at the end of the feeding trial, after which morphological measures and digestive enzyme activities of intestinal mucosa were determined. Weight gain and gain:feed of the pigs were not affected by the dietary treatments (TRT) during the overall feeding trial. Total intestinal length was greater in PROBIO than in ANTI (P<0.05). Wet mucosa weight of the duodenum was not affected by TRT. However, jejunal mucosa weight was greater in PROBIO than in any other group sum of mucosa weights of the duodenum and jejunum was greater (P<0.05) in PROBIO than in ANTI and HERB. The height and width of duodenal villus were not affected by TRT, but crypt depth decreased (P<0.05) in response to HERB and PROBIO vs CON. Specific activities of alkaline phosphatase, sucrase, maltase, lactase, and leucine aminopeptidase in the duodenum and jejunum were not changed by TRT. In conclusion, results suggest that the present dietary treatments have no effects on growth performance of weanling pigs and that of PROBIO enhances intestinal growth and development under a clean experimental setting.
KMT-2017-BLG-0165Lb: A Super-Neptune-mass Planet Orbiting a Sun-like Host Star
Kil Jung, Youn,Gould, Andrew,Zang, Weicheng,Hwang, Kyu-Ha,Ryu, Yoon-Hyun,Han, Cheongho,Yee, Jennifer C.,Albrow, Michael D.,Chung, Sun-Ju,Shin, In-Gu,Shvartzvald, Yossi,Zhu, Wei,Cha, Sang-Mok,Kim, Dong American Astronomical Society 2019 The Astronomical journal Vol.157 No.2
Modification of Starch Composition Using RNAi Targeting Soluble Starch Synthase I in Japonica Rice
( Hye Jung Lee ),( Moo Geun Jee ),( Joon Ki Kim ),( Franz Mc Nogoy ),( Marjohn C Nino ),( Dal A Yu ),( Me Sun Kim ),( Ming Mao Sun ),( Kwon Kyoo Kang ),( Ill Sup Nou ),( Yong Gu Cho ) 한국육종학회 2014 Plant Breeding and Biotechnology Vol.2 No.3
An increasing preference for good eating quality of rice among consumers has become one of the important considerations in rice breeding. Amylose content is a leading factor affecting eating quality of rice. Amylose composition is determined by the relative activity of soluble starch synthase (SSS) and granule-bound starch synthase (GBSS). This study focused on modifying the expression of SSSI gene which is responsible for amylopectin and amylose synthesis in rice by using RNA interference (RNAi) technology. The transgenic rice plants showed various amylose contents (11-17%) in rice grains. Favorable rice lines were selected according to genomic PCR, transgene expression and amylose contents analysis. A semi-quantitative RT-PCR was carried out to determine the expression level of SSSI gene after flowering of transgenic rice and wild type. Down-regulation of SSSI gene in transgenic plants was evident in the decreasing expression in rice grains. Accordingly, scanning electron microscopy (SEM) analysis revealed uniform size with smooth curves starch granules in down-regulation rice lines, in contrast with the non-uniform granules in wild type. Results indicated that RNAi-SSSI transgenic lines produced low amylose contents that fell between glutinous and non-glutinous rice. This study showed that down-regulation of endogenous SSSI may improve the eating quality in rice.