혈소판유래 및 상피성장인자가 치주조직재생에 미치는 영향

최종우,이만섭,권영혁,박준봉,허익,임상철,Choi, Jong-Woo,Lee, Man-Sup,Kwon, Young-Hyuk,Park, Joon-Bong,Herr, Yeek,Lim, Sang-Cheol 대한치주과학회 1997 Journal of Periodontal & Implant Science Vol.27 No.3

6 beagle dogs aged over one and half years and weighed 14 to 16 Kg were utilized in this study, Horizontal furcation defects were induced around 2nd, 3rd, and 4th premolars bilaterally, PDGF-BB in conjunction with EGF and PDGF-BB only were applied in the right and left premolars respectively. 2 animals were sacrificed at 4weeks, 8 weeks, and 12 weeks, after regenerative surgery respectively. Semi-thin sections using glass-knife were stained with toluidine blue for light microscopic study. The results were as follows: 1. At 4 weeks after regenerative surgery, bone formation in the PDGF-BB-applied site was thriving, but bone formation in the PDGF-BB-and-EGF-applied site was depressed. 2. Bony ankylosis was surely shown along the whole exposed root surface applied with PDGF-BB, but it was shown at the root surface near the base of the bone defect where was applied with PDGF-BB in conjunction with EGF. 3. Active bone formation was made from 8 weeks after regenerative surgery in the PDGF-BB- and-EGF-applied site. 4. Bone maturity as well as speed of bone formation in the PDGF-BB-applied site was superior to those in the PDGF-BB-and-EGF-applied site throughout the whole experimental period. Within the above results, PDGF-BB had the strong capability to form the new bone and EGF was not able to prevent the bony ankylosis thoroughly. However, EGF may have the possibility to prevent the bony ankylosis through the suppression of bone formation.

Rennet-induced gels and their mechanical properties

최종우,Choi, Jong-Woo Institute of Agricultural Science 2011 Korean Journal of Agricultural Science Vol.38 No.4

Casein micelles are the basic building block of rennet-induced gels. The stiffness of these gels is increased with reaction time. This is probably due to the continuous participation of activated casein micelles into growing network. Dual binding model of casein micelles, which explains assembly of casein and colloidal calcium phosphate, can provides fairly reasonable explanation for the changes in mechanical properties of rennet-induced gels made from different milk pHs and varying colloidal calcium phosphates. The changes in stiffness of these gels would be used for controlling textural properties of cheeses.

담수양중(湛水壤中) Diazinon 과 Dursban 의 분해(分解)에 관(關)하여

최종우,이규승,Choi, Jong-Woo,Lee, Kyu-Seung 한국환경농학회 1987 한국환경농학회지 Vol.6 No.2

수도용(水稻用) 유기인계(有機燐系) 살충제중에서 조제형태(粗劑形態)로 널리 사용되는 Diazinon제와 Dursban제의 담수토양중(湛水土壤中)에서의 경시적(經時的) 분해(分解)정도를 비교(比較)하고, 아울러 살균(殺菌)과 비살균(非殺菌)토양을 비교하므로서 토양미생물(土壤微生物)에 의한 분해효과(分解效果)를 실험하였다. 아울러 두 약제의 분해대사산물을 GC/MS로 확인하였으며 중요한 결과는 아래와 같다. 1. 항온기(恒溫器$(30{\pm}1^{\circ}C)$)내에서 담수상태(湛水狀態)로 처리한 Diazinon제와 Dursban제의 경시적 변화는 비살균토양(非殺菌土壤)에서 보다 살균토양(殺菌土壤)에서 약 3배(培) 정도 지연되었으며, 따라서 미생물에 의한 분해를 확인할 수 있었다. 2. Diazinon제의 상용농도에서의 반감기는 2.2일이었으며, Dursban 제는 10.8일이었다. 상용농도의 3 배량 고농도 처리에서는 두 약제 모두 평균 1일정도 분해가 지연되었다. 3. Diazinon의 분해대사산물(分解代謝産物)로는 가수분해산물인 0, 0-diethyl phosphorothioate 와 이 화합물의 이량체(二量體)인 sulfotep, 그리고 monooxygenase 에 의한 분해대사물인 Diazoxon, 0,0-diethyl-0-[2-(1-hydroxy-1, 1-dimethyl)-6-methyl]-pyrimidinyl phosphorothioate 그리고 2-isopropyl-6-methyl-pyrimidine-4-one 이 확인되었으며, Dursban 제의 대사산물로는 0, 0-diethyl phosphorothioate 만이 확인되어 주로 esterase 에 의한 분해가 주대 대사경로라고 밝혀졌다. The degradation of two chemicals seem to be clearly affected by soil microbial activity in submerged soil $conditions(30{\pm}1^{\circ}C)$. The Active ingredient of Diazinon disappeared about 5 times faster than that of Dursban. By Applying 300% higher concentrations of both chemicals. under the above soil conditions, however, degradation was retarded by about one day. Some of the metabolites of Diazinon were as follows: 0.0-diethyl phosphorothioate and sulfotep as hydrolytic products, and diazoxon, 0.0-diethyl-0-[2-(1-hydroxy-1, 1-dimethyl)-6-methyl]-pyrimidinyl phosphorothioate and 2-isopropyl-6-methyl-pyrimidine-4-one as degradation products of monooxygenase. But 0. 0-diethyl phosphorothioate was the only methabolite of Dursban.

충남지역(忠南地域) 논토양중 유기염소계(有機鹽素系) 농약(農藥)의 잔류수준(殘留水準)

최종우,이규승,이중길,노길봉,Choi, Jong-Woo,Lee, Kyu-Seung,Lee, Jung-Kil,Noh, Kil-Bong 한국환경농학회 1987 한국환경농학회지 Vol.6 No.2

1986.3.20∼4.6 사이에 충남(忠南)의 대덕(大德), 공주(公州), 금산(錦山), 논산(論山) 및 연기군(燕岐郡) 등 5개 지역(地域)에서 총(總) 108점(點)의 논토양을 채취하여 19종(種), 유기염소계(有機鹽素系) 농약(農藥)을 대상으로 잔류수준(殘留水準)을 조사(調査)하였으며, 중요한 결과를 요약하면 아래와 같다. 1. 모두 12종(種)의 농약성분을 검출(檢出)하였으며, 검출빈도는 P.P'-DDE (67.6%), ${\gamma}-BHC$(54.8%), ${\gamma}-chlordane$(50.9%), 그리고 ${\alpha}-BHC$(47.1%)의 순(順)이었고, 평균잔류량(平均殘留量)은 ${\alpha}-BHC$, ${\gamma}-chlordane$, P.P'-DDD와 P.P'-DDE가 0.001ppm 수준이었다. 2. 검출시료의 평균잔류수준은 ${\beta}$-BHC가 0.001ppm, ${\alpha}-BHC$, ${\gamma}-chlordane$, P.P'-DDT, O.P'-DDT 및 P.P'-DDD가 모두 0.002ppm 수준이었다. 3. 이상(以上)의 결과에서 볼 때, ${\beta}-BHC$, ${\gamma}-chlordane$ 및 DDT의 대사산물(代謝産物)의 잔류성(性)이 비교적 길은 것으로 나타났으나 전반적(全般的)인 잔류수준은 높지 않은 것으로 평가(評價)할 수 있다. Residues of some organo-chlorine pesticides on 108 solis collected from 5 sites of Chungnam avea during March 20-April 6, 1986 were investigated. 12 different kinds of Chemical components were detected showing the highest detection frequency with P.P'-DDE(67.6%) and the lowest with Heptachlor(1.8%). 4 different chemicals, ${\alpha}-BHC$, ${\gamma}-chlordane$, P.P'-DDD and P.P'-DDD and P.P'-DDE showed their average contents in the soils of 0.001 ppm and 0.005ppm for ${\beta}-BHC$, respectively. On the other hand, ${\alpha}-BHC$, ${\gamma}-chlordane$, P.P'-DDT. O.P'-DDT and P.P'-DDD showed 0.002ppm for their average contents of residues, respectively.

기존의 창상봉합과 Histoacryl Blue^®를 이용한 창상봉합의 비교 분석: 전향적 무작위 임상실험

최종우,현경배,김용욱,박병윤,Choi, Jong Woo,Hyun, Kyung Bae,Kim, Yong Oock,Park, Beyoung Yun 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.1

Tissue adhesives have gained popularity for quicker and painless closure of lacerations. The use of tissue glue is currently popular for the closure of superficial lacerations, especially in children. Histoacryl $Blue^{(R)}$(2-N-butylcyanoacrylate) is a topical wound closure that precludes the need for foreign bodies to close wounds. The purpose of this study was to compare the applications of Histoacryl $Blue^{(R)}$(HAB) and conventional suture, regarding cosmetic outcome. To compare the short term and long term results of various repair methods, we designed the prospective, randomized, blind study. Patients with laceration undergoing repair were randomly allocated to conventional suture, subcutaneous suture plus HAB, and HAB only groups. The exclusion criterions were large wound that require large tension for repair or avulsion wound. An independent, blinded observer assessed cosmetic result at 7-10 days after repair and 3-9 months postoperatively. Physician's satisfaction with wound appearance was recorded on 100 mm Visual Analogue Scale(VAS)(0=worst, 100=best). The difference in VAS score between conventional suture method and subcutaneous suture plus HAB methods were not significant. Tissue glue being easy to use with no complications and still resulting in equivalent cosmetic outcomes has several benefits. Especially in the case of children, the wound closure with Histoacryl $Blue^{(R)}$ could be a good alternative for repair of laceration in emergency room.

Theoretical molecular aspects of colloidal calcium phosphate in bovine milk

최종우,Choi, Jong-Woo Institute of Agricultural Science 2011 Korean Journal of Agricultural Science Vol.38 No.3

A simplified model for the colloidal calcium phosphate (CCP) nanocluster was developed from an active role of phosphate in the precipitation of casein (CN)/Ca mixtures and the composition of casein micelles (CM). The possible shape of the CCP nanocluster was selected as a tetrahedron, and we estimated that 4 CN molecules were involved in crosslinking a single CCP nanocluster. Similar values were obtained for the number of CN molecules involved in stabilizing the nanocluster when the number of CNs attached onto each nanocluster surface was deduced from the composition of CM. If one phosphoserine cluster consisted of 3 phosphoserine residues, the theoretical molecular weight and volume for the nanocluster were estimated to be 4,898 g/mol and 2.88 $nm^3$, respectively. It was also shown that the position of Ca present in our model were reasonably located to accommodate the serine phosphate in CN molecule.

대기 환경 중 키랄 유기염소계 농약의 분포 특성

최종우 ( Jong Woo Choi ),김금희 ( Kum Hee Kim ),황승률 ( Seung Ryul Hwang ),이규승 ( Kyu Seung Lee ) 한국환경농학회 2012 한국환경농학회지 Vol.31 No.3

BACKGROUND: The analysis for the concentration and enantiomeric ratio of OCPs have been performed to confirm the distribution and to emonstrate the pollution characteristics of chiral OCPs in ambient air. METHODS AND RESULTS: In ambient air at coastal and inland sites, concentrations and enantiomer fractions (EFs) of heptachlor (HEPT), eptachlor epoxide (HEPX), trans-chlordane (TC), cis-chlordane (CC), xychlordane (OXY), 2,4`-DDT, 2,4`-DDD with HRGC/HRMS were investigated to understand source and distribution of chiral organochlorine pesticides (OCPs) in ambient air. The mean concentrations of OCPs in ambient air were at the range of 0.027(heptachlor)∼1.279 (4,4`-DDT) pg/m3 and 0.0005 (heptachlor)∼0.1043 ng/g d.w. (TC), respectively, The mean EFs of OCPs in ambient air were at the range of 0.73 (HEPX)∼0.45 (CC). Both preferential depletions of (+) and (-) enantiomer were observed for CC, indicated by EFs either <0.5 or >0.5, while preferential depletions of (-) enantiomer which mean EFs <0.5 were observed for chiral OCPs except TC and MC-5. CONCLUSION: OCPs in ambient air have been distributed from soil, but some of them such as chlordane, DDT etc. might have been introduced by long-range atmospheric transport, considering EFs by chiral analysis and trajectory analysis.

산업기술유출범죄 수사 의지에 영향을 미치는 요인 분석

최종우 ( Choi Jong Woo ),이창무 ( Lee Chang Moo ) 한국경찰학회 2019 한국경찰학회보 Vol.21 No.5

4차 산업혁명 시대가 도래하면서 산업기술의 경제적 가치는 높아지고 있다. 그 부작용으로 고부가가치의 산업기술에 대한 범죄도 점차 다양해지고, 그 수도 늘고 있다. 산업기술유출범죄에 대한 경제적 피해가 커지면서, 산업기술유출범죄를 수사하는 경찰의 역할이 점차 중요해지고 있다. 선행 연구에서도 산업기술유출범죄에 있어서 경찰의 역할이 중요하다는 점을 인정하고 있으나, 효과적인 산업기술유출범죄 대응책으로서 경찰 내부 조직 개편 등 ‘조직 재정비’라는 단편적인 해결책 제시에 그치고 있다. 그러나 본 연구에서는 산업기술유출 방지에 있어서 조직 재정비와 같은 해결책 이외에 수사관 개인의 수사의지가 중요하다고 생각하여, 수사관들의 수사의지에 영향을 미치는 요인들을 탐색하였다. 경찰청, 전국의 지방청, 경찰서 직원들을 대상으로 설문조사를 한 뒤 이를 분석, 산업기술유출에 대한 인식과 언론에 대한 접촉도가 수사의지에 유의미한 영향을 미친다는 결과를 도출하였다. 선행연구의 부재로 수사의지에 대한 조작적 정의가 미흡한 점이 한계점으로 지적될 수 있으나, 산업보안 분야에서 상대적으로 주목받지 못했던 경찰 개인의 의지에 집중하여 영향을 끼치는 요인을 실증적으로 밝혀내려고 했다는 점에서 의의가 있다. With the advent of the fourth industrial revolution era, the economic value of industrial technology has been increasing. As the result of the side effects, crimes against high-value-added industrial technologies are increasingly diverse, and the number is increasing. As the economic damage to industrial technology leakage crimes grows, the role of police investigating industrial technology leakage crimes is becoming increasingly important. Although the police's role in crime of industrial technology leakage was recognized in the preceding researches, They only suggested the piecemeal solutions such as the reorganization of the police's internal organization as the effective countermeasure against crimes of industrial technology leakage. However, I think that the will to investigate of each investigator is important in preventing industrial technology leaks, so we explored factors that affect the will of the investigators. Based on the survey conducted on the employees of the National Police Agency, regional offices and police stations across the country, the analysis that the perception of industrial technology leaks and contact with the media have significant impacts on the will of the investigation was concluded. The lack of a manipulative definition of investigation will may be pointed out as a limitation due to the lack of prior research, but it is meaningful that this study focuses on the will of individual police officers who were relatively unnoticed in the industrial security field and tries to empirically identify the factors affecting them.

첨단 도로 교통 체계를 위한 무인 영상 감시 장치의 운영 방안에 관한 연구

최종우(Jong-Woo Choi),이태훈(Tae-Hoon Lee),이종민(Jong-Min Lee),홍근선(Geun-Seon Hong),김용득(Yong-Deak Kim) 대한전자공학회 1995 대한전자공학회 학술대회 Vol.1995 No.6

철손을 고려한 유도전동기의 벡터 제어

崔鍾宇(Jong-Woo Choi),鄭大雄(Dae-Woong Chung),薛承基(Seung-Ki Sul) 대한전기학회 1997 전기학회논문지 Vol.46 No.7