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김진철,최석철,Kim, Jin-Chul,Choi, Seok-Cheol 한국군사과학기술학회 2008 한국군사과학기술학회지 Vol.11 No.1
Many advanced countries including the U.S. consider defense standardization as a critical task for the efficient acquisition and effective operation of weapon systems and have implemented the appropriate standardization policy by synchronizing the defense acquisition strategies and nation standardization policy with defense standardization. It is required to develop the long-term defense standardization policy that can cope with the future domestic and international defense environmental changes. Therefore, it is an inevitable task to investigate the standardization trends and strategy in the domestic and international perspectives. The study aims to provide the vision of defense standardization policy, act/regulation, organization/personnel, education/training and information system.
김진철,함돈일,Jin Chul Kim,Don Il Ham 대한안과학회 2009 대한안과학회지 Vol.50 No.1
Purpose: To investigate the clinical characteristics and treatment of intermediate uveitis under new diagnostic standards. Methods: Medical records of patients diagnosed with pars planitis or intermediate uveitis were followed for more than 6 months, and retrospectively reviewed. Results: A total of 90 patients and 117 eyes were enrolled in the study. The mean age was 40.1 years, and the mean follow-up period was 43.0 months. Thirty percent of cases were bilateral. The most common initial symptom was decreased visual acuity. Snowbank was detected in 39.3%, snowballs in 15.4%, vitritis in 96.6%, and vasculitis in 56.4%. Common complications includedcystoid macular edema (57.3%), cataracts (43.6%), and epiretinal membrane (36.8%). Therapies included topical steroids (82.9% of cases), posterior sub-Tenon steroid injection (45.3% of cases), systemic steroid administration (67.8% of cases), and immunosuppressants (28.7% of cases). Vitrectomy was performed in 11.1% of patients due to complications such as epiretinal membrane and traction retinal detachment. The mean initial and final visual acuities were 0.67 and 0.74, respectively. Conclusions: The patients in this study experienced various courses of symptoms that required different treatment plans. Future investigations may corroborate these results.
김진철,양성철,조윤호,김남호,Kim, Jin-Cheol,Yang, Sung-Chul,Cho, Yoon-Ho,Kim, Nam-Ho 한국도로학회 2004 한국도로포장공학회 논문집 Vol.6 No.1
The characteristics of concrete strength and fracture parameters of recycled aggregate concrete were investigated to apply to the concrete pavements. As the results, the early strength of recycled aggregate concrete showed to be lower than that of natural coarse aggregate concrete, whereas strength at 28 days showed to be similar. Young's modulus of recycled aggregate concrete was lower than that of natural coarse aggregate concrete due to the difference of aggregate strength. And recycled aggregate concrete contained with ground granulated blast furnace slag seemed to have an effect of strength increasing. The critical stress intensity factor of recycled aggregate concrete at the early age was increased, and converged to be similar, compared to natural aggregate concrete at later age. The reliability of two-parameter fracture model was identified by the good correlation between the theoretical value computed by P-CMOD relationship and experimental results for Young's modulus and tensile strength. 본 연구는 재생골재를 사용한 콘크리트의 강도 및 파괴특성을 고찰하므로써 콘크리트 포장체에 적용성 여부를 검토하기 위해 수행하였다. 재생콘크리트의 초기강도는 낮았으나 재령 증가에 따라 기준콘크리트와 거의 유사한 값을 나타내었으며. 탄성계수는 골재 강성 차이로 인하여 낮게 나타났다. 또한 고로슬래그 미분말을 혼합한 재생콘크리트의 강도개선효과를 확인할 수 있었다. TPFM에 의한 파괴에너지는 초기재령에서 재생콘크리트의 파괴특성이 우수한 것으로 나타났으나, 재령증가에 따라 기준콘크리트와 유사한 값으로 나타났다. 또한 P-CMOD 측정결과로부터 이론적으로 구한 탄성계수 및 인장강도와 실험으로 구한 탄성계수 및 쪼갬인장 강도사이의 상관성은 매우 높은 결과를 나타내어 시험방법의 신뢰성을 확인할 수 있었다.
라식 수술 후 압평안압계와 비접촉성 안압계 측정치간 큰 차이를 보인 1예
김진철,정태영,기창원.Jin Chul Kim. M.D.. Tae Young Chung. M.D.. Chang Won Kee. M.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.6
Purpose: To report the case of a glaucoma patient with a history of LASIK surgery who presented with a wide discrepancy in intraocular pressure between the Goldmann applanation tonometry and non-contact tonometry. Methods: A 20-year-old male glaucoma patient was referred to our clinic with a chief complaint of blurred vision in his right eye. The patient had a history of uneventful bilateral LASIK surgery. Upon our initial examination, his best-corrected visual acuity in the right eye was 0.04 and his right eye IOP was 14 mmHg by Goldmann applanation tonometry and 40 mmHg by non-contact tonometry. A slit lamp examination showed corneal epithelial edema with diffuse interface opacities. The central corneal thickness in the right eye was 587 ?m. An ultrabiomicroscopy demonstrated an interface fluid accumulation between the LASIK flap and the stromal bed. The patient was diagnosed with juvenile open-angle glaucoma and was scheduled for a trabeculectomy. Results: Seven days after trabeculectomy, the patient`s vision in the right eye improved to 0.7 and his IOP was 12 mmHg by Goldmann applanation tonometry and 14 mmHg by non-contact tonometry. In addition, the corneal epithelial edema, interface opacities, and fluids had all resolved and the central corneal thickness was reduced to 489 ?m. Conclusions: In eyes that have undergone LASIK surgery, the IOP measured by Goldmann applanation tonometry may underestimate the true pressure due to fluid accumulation under the LASIK flap. In such cases, non-contact tonometry can be a convenient and a reliable method for determining treatment plan.
고삼이 항암제 cisplatin의 췌$\cdot$심장 부작용 감소에 미치는 영향
김진철,임성철,정태영,서정철,한상원,Kim, Jin-Cheo,Lim, Seong-Chul,Jung, Tae-Young,Seo, Jung-Chul,Han, Sang-Won 대한동의생리학회 2005 동의생리병리학회지 Vol.19 No.3
The objective of this study is to investigate the inhibitor effects of an traditional oriental herb, Sophora flavescens on the pancreatic & cardiac side effects of chemotherapy were studied by using Bl6-BL6 melanoma-injected C57BL6 mouse tumor model. In this study, the effects of an traditional oriental herb, Sophora flavescens, on the side effects of chemotherapy were studied using B16 melanoma-injected C57BL6 mouse tumor model. Anticancer drugs widely used in clinical situation. Sophora flavescen has significant effect on the reduction of the side effects of chemotherapy. Water extract of Sophora flavescens significantly inhibited cisplatin-induced increase of amylase (AMY) which is a good indicator of pancreatic toxicity. Sophora flavescens extract does not decrease the anti-tumor activity of cisplatin showing that it can selectively inhibit side effects of anticancer drugs preserving beneficial effect. Theses results suggest a possibility that Sophora flavescens extract can be used for cancer patients for the reduction of the side effects and improving the quality of life during chemotherapy of cancer patients.
김진철 ( Kim Jin Chul ) 한국장애인개발원 2011 장애인복지연구 Vol.2 No.3
일반학생들이 초 · 중 · 고등학교를 거치면서 자신의 미래를 위한 진로악 직업에 관심을 두고, 대학에서 자신이 원하는 전공을 선택하거나 자신의 강점과 흥미를 살린 직업을 얻고자 준비하고 있는 것과 마찬가지로 장애학생도 자신의 능력에 따라 미래를 준비해야만 한다. 그러나 장애를 가진 경우는 대부분 장애로 인해 수반되는 어려움 때문에 선택의 폭이 좁을 뿐 아니라 미래를 준비 하는데 더 많은 시간이 요구된다. 그러므로 장기계획에 의거하여 좀 더 빠른 시기에 미래를 계획 할 수 있도록 지원하고, 자신의 강점을 살려서 직업을 선택할 수 있도록 지도되어야 하는 전환교육이 강조되는 것에 반해 65.0%의 교사가 특수학급 교실에서 전환교육을 실시하고 있지만 교내 여건이 충분하다고 인식하는 교사가 8.3%에 지나지 않을 정도로 적절치 않은 학습환경으로 인한 전환교육의 어려움이 있다. 또한 대부분의 특수교사(75.4%)가 초등학교 이전에 전환교육을 실시하여야 한다고 답해 직업인식 단계에서의 초등학교 특수학급의 전환교육이 중요하다. 이에 전환교육을 고려한 특수학급 공간구성의 분석 모델을 개발하고 분석 자료(초등학교 특수학급 전환교육 요소 그 요소에 대한 공간 및 설비 · 교구의 현황, 특수교사의 요구도)를 적용하여 전환교육 4개 영역(개인생활, 사회생활, 여가생활, 직업생활)에 적합한 특수학급 공간구성 방안의 연구 결과는 다음과 같다. 개인생활 중점의 공간구성은 기본공간과 세탁을 할 수 있는 작업공간, 바닥에 난방설비를 하여 바닥활동도 가능한 동적활동공간이 확보되고 정적 활동공간에 화장실까지 설치된 다양한 활동이 가능한 공간으로 구성해야 한다. 사회생활 중점의 공간구성은 동영상이나 사진을 보고 배울 수 있는 학습공간과 인사하기와 공공질서 지키기 등의 모의 훈련에 필요한 같은 동적활동공간이 확보되어야 한다. 여가생활 중점의 공간구성은 동영상이나 사진을 이용한 학습공간과 인라인스케이트를 탈 때의 자세 등을 연습할 수 있는 동적활동공간, 요리를 할 수 있는 작업공간과 컴퓨터와 주변기기를 이용할 수 있는 공간, 식물을 재배할 수 있는 공간 구성이 필요하다. 직업생활 중점의 공간구성은 직업알기 활동을 할 수 있는 학습공간과 조작기능을 익힐 수 있는 작업대가 갖추어진 작업공간으로 구성해야 한다. 이상의 4가지 방안을 바탕으로 학교의 특성에 맞게 재구성하면 합리적인 특수학급 공간을 구성할 수 있을 것이다. Equipment, teaching tools and spatial layout for elementary special class should be supplied systematically considering the order that is focused on exercise of transitional education - personal life > social life > occupational life, learning space for transitional education > dynamic activity space > worktable, computer > cooking, sporting goods, static activity space, storage space, washstand > laundry, plant-growing, floor warming, washroom. Based on the analysis of 4 areas - characteristics of each field of transitional education, demands from special class teachers, requirements and the present state of equipment, teaching tools, and spatial layout - suitable spatial layout should be suggested. Personal life focused space should consists of basic space, workplace for laundry, dynamic activity space with floor-heated, and static activity space with multi-purpose space including the washroom. Social life focused space should be equipped with space for learning with videos and pictures, and dynamic activity space for training public etiquette such as greeting. leisure focused space needs learning space using videos and pictures, dynamic activity space for exercising the postures of inline skating, cooking space, space for computer related works, and plant-growing. Occupational life focused space should have learning space for job-exploration and working space with worktables for operation skills. If reorganized according to the characteristics of special classes on the basis of these 4 space demands, the reasonable special classes could be organized.
병풍쌈의 에탄올 추출물의 항산화 기능 및 DNA의 산화적 손상 억제작용
김진철 ( Jin Chul Kim ),김종대 ( Jong Dai Kim ),박희준 ( Hee Juhn Park ),신인철 ( In Chul Shin ),이진하 ( Jin Ha Lee ),이현용 ( Hyeon Yong Lee ),한상화 ( Sang Hwa Han ),안주희 ( Ju Hee Ahn ),최근표 ( Geun Pyo Choi ),박애리 ( Ae Ri 한국응용생명화학회(구 한국농화학회) 2011 Journal of Applied Biological Chemistry (J. Appl. Vol.54 No.4
산나물의 일종인 병풍쌈[Cacalia firma Komar. (CFK)]은 산지에서는 인기 있는 자생식품 자원이다. 본 연구의 목적은 CFK의 ethanol (EtOH) 추출물의 1,1-diphenyl-2-picryl-hydrazyl, 2,2-azinobis(3-ethylbenozothiazoline-6-sulfonic acid) diammonium salt, ferric reducing/antioxidant power 분석법 및 electron spin resonance spectroscopy에 의한 유리기의 억제작용과 agarose electrophoresis법에 의한 산화적 DNA damage에 대한 보호효과를 조사하는 것이다. HO·유리기에 의한 CFK EtOH 추출물의 DNA damage 보호효과는 항산화 참고 물질로 epicatechin, ascorbic acid 및 trolox등과 비교하였다. CFK EtOH 추출물 중의 총 페놀물질 분석은 Folin-Ciocalteu의 방법으로 행하고 표준물질로 gallic acid equivalents를 사용하여 함량을 표시하였다. CFK EtOH 추출물 중의 총 페놀 함량은 잎 과 줄기 부분에서 각각 161.53±1.07 μg/g, 142.45±0.56 μg/g이 확인 되었다. CFK EtOH 추출물 중의 유리기들에 대한 항산화 기능과 HO·기에 의한 DNA 손상에 대한 보호효과는 각각 약 60% 이상의 기능을 보였다. The Korean edible mountainous vegetable, byeongpungssam, [Cacalia firma Komar. (CFK)] is a wild plant found in the intermountain areas in Korea. The aim of this study was to investigate its free radical scavenging activity using 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2-azinobis(3- ethylbenozothiazoline-6-sulfonic acid) diammonium salt (ABTS), ferric reducing/antioxidant power (FRAP) assays, an electron spin resonance spectroscopy (ESR). We also examined its protective effect against oxidative DNA damage using agarose electrophoresis of ethanol (EtOH) extract of CFK. The protective activity of the extract against the DNA damage induced by HO·radicals was compared to epicatechin, ascorbic acid (AsA) and trolox as reference antioxidant compounds. Total phenolic content in the extract was determined spectrometrically according to the Folin- Ciocalteu procedure and calculated as gallic acid equivalents (GAE). Total polyphenolic content of the extract was measured in the leaves (161.53±1.07 μg/g) and shoot (142.45±0.56 μg/g). The antioxidant potential of the extracts against some radicals and DNA damage by HO·radicals showed over 60%, respectively.