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Real-World National Colonoscopy Volume in Korea: A Nationwide Population-Based Study over 12 Years
Jae Myung Cha,Min Seob Kwak,Hyun-Soo Kim,Su Young Kim,Sohee Park,Geun U Park,Jung Kuk Lee,Soo Jin Kim,Hun Hee Lee,Joo Sung Kim,Won Ho Kim,Big Data Research Group of the Korean Society of Gastroenterol 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.3
Background/Aims: Little is known about the national colonoscopy volume in Asian countries. This study aimed to assess the national colonoscopy volume in Korea over a 12-year period on the basis of a nationwide population-based database. Methods: We conducted a population-based study for colonoscopy claims (14,511,158 colonoscopies performed on 13,219,781 patients) on the basis of the Korean National Health Insurance Service database from 2002 to 2013. The 12-year national colonoscopy burden was analyzed according to patient age, patient sex, and healthcare facility type. Results: The overall volume of colonoscopy increased 8-fold over the 12-year period. The annual colonoscopic polypectomy rate significantly increased in all patient sex and age groups over the 12-years period (all p<0.001). The yearly colonoscopic polypectomy rate for men was significantly increased compared with that for women (2.3% vs 1.7%, p<0.001) and for the screening-age group compared with that for the young-age group (2.0% vs 1.6%, p<0.001). The yearly colonoscopic polypectomy rate relative to the total colonoscopy volume significantly increased in primary, secondary, and tertiary facilities by 2.4%, 1.9%, and 1.4% during the 12-year period (all p<0.001). In addition, the annual colonoscopy volume covered by high-volume facilities significantly increased by 1.8% in primary healthcare facilities over the 12-year period (p<0.001). Conclusions: Healthcare resources should be prioritized to allow adequate colonoscopic capacity, especially for men, individuals in the screening-age group, and at primary healthcare facilities. Cost-effective strategies to improve the quality of colonoscopy may focus on primary healthcare facilities and high-volume facilities in Korea.
Liquid Crystalline Properties of Dimers Having o-, m- and p- Positional Molecular Structures
Park, Joo-Hoon,Choi, Ok-Byung,Lee, Hwan-Myung,Lee, Jin-Young,Kim, Sung-Jo,Cha, Eun-Hee,Kim, Dong-Hyun,Ramaraj, B.,So, Bong-Keun,Kim, Kyung-Hwan,Lee, Soo-Min,Yoon, Kuk-Ro Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.5
With the objective to design and synthesis of Schiff's base symmetrical liquid crystal dimmers and to study the effect of molecular structure variation ($o-ortho$, $m-meta$, $p-para$) and change in alkoxy terminal chain length on mesomorphic properties of liquid crystals, We have synthesized Schiff base dimers from dialdehyde derivative containing 2-hydroxy-1,3-dioxypropylene as short spacer with aniline derivatives having different lengths of terminal alkoxy chains ($n$ = 5, 7, 9). The chemical structure of the final products was characterized by proton nuclear magnetic resonance ($^1H$ NMR) spectroscopy and fourier transform infrared (FT-IR) spectroscopy. The mesomorphic properties and optical textures of the resultant dimers were characterized by differential scanning calorimetry (DSC) and polarized optical microscopy (POM). The existence of smectic A phase transition was confirmed by the observation of batonnets and fan shaped textures in optical microscopy when compound were heated from crystalline phase. All of the dimers of this series, with the exception of $\mathbf{2S_5}$ -ortho, -meta, -para, were thermotropic liquid crystal. The compound $\mathbf{2S_9}$ -meta was monotropic, while the rest were enantiotropic. It was found that the change in terminal alkoxy chain length has pronounced effect on the mesomorphic properties. The temperature range of smectic A phase window widens with increasing alkoxy chain length.
Thermotropic Liquid Crystalline Dimers with Varying Alkoxy Terminal Chain Length
Park, Joo-Hoon,Choi, Ok-Byung,Lee, Hwan Myung,Lee, Jin-Young,Kim, Sung-Jo,Cha, Eun-Hee,Park, Seon-Nam,So, Bong-Keun,Kim, Ran-Hee,Sohn, Tae-Wha,Lee, Chang Sin,Lee, Soo-Min,Yoon, Kuk-Ro Informa UK (TaylorFrancis) 2014 Molecular Crystals and Liquid Crystals Vol.599 No.1
Jin Young Park,Kyung Ho Hong,Jae Hyung Lee,Kyung Soo Oh,Seok Won Chung,Seung Hyub Jeon,Myung Joo Cha 대한견주관절의학회 2017 대한견주관절학회지 Vol.20 No.2
Background: Although there have been multiple reports on surgical outcomes of superior labral anterior to posterior (SLAP) lesions in overhead athletes, only a few reports exist in the literature about the results of nonoperative treatment in elite (collegiate or professional) overhead athletes. To determine the clinical outcomes of nonoperative treatment of SLAP lesions in elite overhead athletes. Methods: Between January 2006 and December 2011, 69 patients were selected. Initial arthroscopic SLAP repair was performed in 19 patients and of the 50 patients who underwent nonsurgical treatment, such as range of motion gain and periscapular muscle strengthening, 14 patients were converted to surgical treatment; 5 patients were lost to follow-up. Medical records of 31 elite overhead athletes who underwent nonsurgical treatment were retrospectively reviewed. Four clinical outcome measures were used: visual analogue scale (VAS) for pain, VAS for satisfaction, American Shoulder and Elbow Surgeons (ASES) score, and subjective feeling of recovery. Results: The average follow-up period was 35.9 months (range, 24–62 months). The VAS for pain decreased from 6.5 to 2.2 (p<0.01) and VAS for satisfaction was 7.6. The ASES score increased from 54.1 to 85.9 (p<0.01). The overall average value of subjective feeling of recovery was 72%. Twenty-three out of 31 elite athletes (74.2%) returned to play after rehabilitation; these 23 athletes performed at the same or higher levels after rehabilitation. Conclusions: Nonsurgical treatment in elite overhead athletes with SLAP lesion should be considered as a treatment option.
Liquid crystal dimers having vary oxyethylene flexible spacers
Park, Joo Hoon,Singu, Bal Sydulu,Choi, Ok Byung,Lee, Hwan Myung,Lee, Jin Young,Kim, Sung Jo,Cha, Eun Hee,Park, Seon Nam,Kwak, Myeong Heon,So, Bong Keun,Kim, Ran Hee,Lee, Soo Min,Yoon, Kuk Ro Informa UK (TaylorFrancis) 2017 Molecular Crystals and Liquid Crystals Vol.650 No.1
<P>In this article, we are prepared that the liquid crystal dimers have aromatic-ester type mesogenic units or aromatic-Schiff base typemesogonic units and confirmed by H-1-NMR spectrometry. The mesomorphic and optical properties of the resultant dimers were studied by differential scanning calorimetry and polarizing optical microscopy.</P>
김영하,최규용,박주현,정인식,정규원,박승만,김부성,최명규,선희식,차상복,이안희,최영진,한치화 대한소화기내시경학회 1991 Clinical Endoscopy Vol.11 No.2
Carcinosarcoma of the esophagus is regarded as a rare malignant neoplasm composed of both carcinomatous and sarcomatous elements. Esophageal carcinosarcoma classified into 3 subgroups, pseudosarcoma, so called carcinosarcoma, and true carcinosarcoma. we report a case of large polypoid tumor consist of squamous cell carcinoma, undifferentiatred small cell and spindle cell proliferation. The patient was 47 year-old man who had suffered from dysphasia and substernal chest pain for 2 months. A protruded tumor in size of 8x4x3.5 cm with stalk was found in midesophagus at the level of 28 cm from the incisor. The tumor was round with smooth surface stained with Lugol solution. There were multiple erosions at the stalk of the tumor, Partial esophagectomy and esophagogastrostomy was done, Undifferentiated small cell was confirmed by immunoreactivity to neuron specific enolase and electron microscopic findings.
( Jung Lok Lee ),( Jae Myung Cha ),( Hye Min Lee ),( Jung Won Jeon ),( Min Seob Kwak ),( Jin Young Yoon ),( Hyun Phil Shin ),( Kwang Ro Joo ),( Joung Il Lee ),( Dong Il Park ) 대한장연구학회 2017 Intestinal Research Vol.15 No.1
Background/Aims: Western surveillance strategies cannot be directly adapted to the Korean population. The aim of this study was to estimate the risk of metachronous neoplasia and the optimal surveillance interval in the Korean population. Methods: Clinical and pathological data from index colonoscopy performed between June 2006 and July 2008 and who had surveillance colonoscopies up to May 2015 were compared between low- and high-risk adenoma (LRA and HRA) groups. The 3- and 5-year cumulative risk of metachronous colorectal neoplasia in both groups were compared. Results: Among 895 eligible patients, surveillance colonoscopy was performed in 399 (44.6%). Most (83.3%) patients with LRA had a surveillance colonoscopy within 5 years and 70.2% of patients with HRA had a surveillance colonoscopy within 3 years. The cumulative risk of metachronous advanced adenoma was 3.2% within 5 years in the LRA group and only 1.7% within 3 years in the HRA group. The risk of metachronous neoplasia was similar between the surveillance interval of <5 and ≥5 years in the LRA group; however, it was slightly higher at surveillance interval of ≥3 than <3 years in the HRA group (9.4% vs. 2.4%). In multivariate analysis, age and the ≥3-year surveillance interval were significant independent risk factors for metachronous advanced adenoma (P =0.024 and P =0.030, respectively). Conclusions: Patients had a surveillance colonoscopy before the recommended guidelines despite a low risk of metachronous neoplasia. However, the risk of metachronous advanced adenoma was increased in elderly patients and those with a ≥3-year surveillance interval. (Intest Res 2017;15:109-117)