상부(上部) 옥천층(沃川層)의 암석학적(岩石學的) 및 지구조적(地構造的) 해석(解釋)에 관(關)한연구(硏究)

김옥준,윤정수,Kim, Ok Joon,Yoon, Jeong Su 대한자원환경지질학회 1980 자원환경지질 Vol.13 No.2

In spite of the fact that the Okcheon system has been rather intensively studied by many geologists since 1945, it still remains as a controversal problem as to its stratigraphy and geologic age. Present study has mainly focused on the upper members of the Okcheon system, namely the Hwanggangri and the Kunjasan formations so as to clarify the lithology, the depositional environment and the tectonic evolution of the formations. The Kunjasan formation lying unconformably over the Hwanggangri formation which is supposed to be a meta-tillite is interpreted as a metamorphosed calcareous argillaceous and/or arenaceous sediments on contract to the idea postulated by some geologists that it was a derivative of silicified Hwanggangri formation. Lithology of the Kunjasan and the Hwanggangri formation is quite different in that the former is white in color, contains few pebbles, and mostly composed of diopside and detrital quartz, whereas the latter is black to dark in color, contains abundant and variable kinds of pebbles, and composed of more argillacous matrix that has been metamorphosed to hornfels. The Hwanggangri and the Kunjasan formations were deposited in the rather deep sea which has transgressed toward northeast from southwest in the late Precambrian time, and the writer (1970) had formerly designated it as Okcheon Paleogeosyncline. With the beginning of Paleozoic era, Okcheon neogeogyncline was formed to the northeast of the old paleogeogyncline area. The transgression of the sea had proceeded toward southwest in which Cambrian strata were accumulated. During this period the area occupied formerly by the paleogeosyncline was uplifted, so that most of the Hwanggangri and the Kunjasan formations were eroded away except in the area close to the neogeosyncline sea coast. This is the reason why the Hwanggangri and the Kunjasan formations are cropped out presently in the area of the vicinity of contact zone of the paleo- and neogeosyncline zones. The age of the Okcheon system has been reconfirmed to be Precambrian from the view of the facts that 1) the Hanggangri formation, the upper member of the Okcheon system is meta-tillite and correlated to the Precambrian tillite in the Yantze basin in China, 2) the Okcheon system has been moderately metamorphosed while other formations of the same age, if it is Paleozoic or later, have not been metamorphosed, and 3) tectonic history and limited areal distribution of the Hwanggangri and the Kunjasan formations is suggestive of Precambian age.

원문 : Dexamethasone 및 전기 자극 처치 시 근세포로부터 유발된 exosome의 항 근위축 및 근비대 관련 microRNA 및 단백질의 변화에 미치는 효과

김정석 ( Jeong Suk Kim ),박소영 ( So Young Park ),윤정수 ( Chung Su Yoon ),박대령 ( Dae Ryoung Park ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.4

본 연구의 목적은 골격근 세포에 dexamethasone (Dex) 및 전기 자극(ES) 처치 시 발생하는 microRNA(miR)가 각각의 자극에 따라 어떠한 profile을 가지게 되며, 이러한 exosome을 골격근 primary cell에 처치 시 근위축 및 근비대 관련 인자의 인산화가 어떻게 변하는지를 규명하기 위한 것이었다. C2C12 세포주에 Dex 및 ES를 처치하여 골격근 세포로부터 유리된 exosome의 miR의 profile을 분석하였으며, 이러한 과정에서 얻어진 exosome을 골격근 primary cell에 재처리하여 골격근 세포에서의 근위축 및 근비대 관련 인자의 인산화 변화를 관찰하였다. C2C12 세포주에 Dex 혹은 ES를 처치한 결과, 근위축 관련 miR인 miR-1, miR-206, miR-322와 근비대 관련 miR-23a의 발현 양상이 유의하게 차이나는 것을 확인하였다. 또한 이러한 세포에서 얻어진 exosome을 골격근 primary cell에 처치한 결과, Dex를 처치한 세포에서 얻어진exosome은 근위축 관련 인자인 FOXO와 MuRF의 인산화를 증가시키는 것에 비해 ES를 처치한 세포에서 얻어진 exosome은 근비대관련인자인 mTOR와 p70S6K의 인산화를 증가시키는 것으로 나타났다. 이러한 결과는 각각의 신호체계에 의해 발생되는 골격근내 exosome이 세포의 신호전달 체계에 중요한 역할을 하고 있음을 제시하고 있으며, exosome에 의한 miR의 전달이 근위축 및 근비대와 관련된 신호단백질의 인산화를 조절할 수 있음을 제시하고 있다. The purpose of this study was to examine the effect of dexamethasone (Dex) treatment and electrical stimulation (ES) on skeletal muscle cell derived exosome`s microRNA (miR) profile and its effect on skeletal muscle signal protein expression. Exosome obtained from two different C2C12 cell were treated with Dex or ES. Then we profiled exosome`s miR expression and atrophy related miR-1, miR-206, miR-322 were significantly increased with DEX however, hypertrophy related miR-23a was significantly increased only in the ES. Further we treated two different types of exosome to Dex treated skeletal muscle primary cell and two types of exosome differently regulated atrophy related protein (FOXO/MurF) and hypertrophy related protein (mTOR/p70S6K) phosphorylaton. In conclusion, the results indicate that atrophy or hypertrophy signal induces different exosome including different profile of miR and it plays important role in skeletal muscle atrophy and hypertrophy.

Aucubin, Catalpol, and GABA Content in Different Organ of Rehmannia glutinosa Cultivars

Sang Hoon Lee(이상훈),Jeong Su Yoon(윤정수),Jae Kwang Kim(김재광),Chun Geon Park(박춘근),Mok Hur(허목),Seong Cheol Koo(구성철),Mei Lan Jin,Woo Moon Lee(이우문),Jae Ki Chang(장재기),Yeon Bok Kim(김연복) 한국약용작물학회 2017 한국약용작물학회 학술대회논문집 Vol.2017 No.1

上部 沃川層 의 巖石學的 및 地構造的 解釋 에 關한 硏究

Ok Joon Kim(金玉準),Jeong Su Yoon(尹正守) 대한자원환경지질학회 1980 자원환경지질 Vol.13 No.2

In spite of the fact that the Okcheon system has been rather intensively studied by many geologists since 1945, it still remains as a controversal problem as to its stratigraphy and geologic age. Present study has mainly focused on the upper members of the Okcheon system, namely the Hwanggangri and the Kunjasan formations so as to clarify the lithology, the depositional environment and the tectonic evolution of the formations. The Kunjasan formation lying unconformably over the Hwanggangri formation which is supposed to be a meta-tillite is interpreted as a metamorphosed calcareous argillaceous and/or arenaceous sediments on contract to the idea postulated by some geologists that it was a derivative of silicified Hwanggangri formation. Lithology of the Kunjasan and the Hwanggangri formation is quite different in that the former is white in color, contains few pebbles, and mostly composed of diopside and detrital quartz, whereas the latter is black to dark in color, contains abundant and variable kinds of pebbles, and composed of more argillacous matrix that has been metamorphosed to hornfels. The Hwanggangri and the Kunjasan formations were deposited in the rather deep sea which has transgressed toward northeast from southwest in the late Precambrian time, and the writer (1970) had formerly designated it as Okcheon Paleogeosyncline. With the beginning of Paleozoic era, Okcheon neogeogyncline was formed to the northeast of the old paleogeogyncline area. The transgression of the sea had proceeded toward southwest in which Cambrian strata were accumulated. During this period the area occupied formerly by the paleogeosyncline was uplifted, so that most of the Hwanggangri and the Kunjasan formations were eroded away except in the area close to the neogeosyncline sea coast. This is the reason why the Hwanggangri and the Kunjasan formations are cropped out presently in the area of the vicinity of contact zone of the paleo- and neogeosyncline zones. The age of the Okcheon system has been reconfirmed to be Precambrian from the view of the facts that 1) the Hanggangri formation, the upper member of the Okcheon system is meta-tillite and correlated to the Precambrian tillite in the Yantze basin in China, 2) the Okcheon system has been moderately metamorphosed while other formations of the same age, if it is Paleozoic or later, have not been metamorphosed, and 3) tectonic history and limited areal distribution of the Hwanggangri and the Kunjasan formations is suggestive of Precambian age.

환경변화에 따른 일회성 운동이 흰쥐 골격근 내 Heat Shock Proteins 및 골격근 손상인자에

고영호(Ko Young-Ho),윤정수(Yoon Chung-su),하태균(Ha Tae-Geun),김정석(Kim Jeong-Seok) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.3

The purpose of this study is to determine the expression of a acute endurance exercise both in cold(2℃) and hot(34℃) temperatures on the skeletal muscle. The main purpose of this study is to the effects of cold and hot temperatures to the heat shock protein 70, heat shock protein 27 and blood lactate, plasma CK using rats as the exercise. Adult male Sprague-Dawley rats were randomly placed in one of three temperature groups (normal, hot, cold). The treadmill run with an intensity of 26m/min, 10°intensity and soleus(SOL) and extensor digitorum longus(EDL) muscle extracted at 30, 60, 90 min during the exercise. The western blotting analyzed the expression of HSP70 and HSP27 during the exercise, the increased HSP27 protein in the SOL and EDL tissues of the cold, hot and normal temperatures were observed. However, it was observed that only SOL tissues increased HSP70 protein in both cold and hot temperatures. These results implied that increased apoptotic factor by cold and hot temperatures could cause the expression of HSP70 and HSP27 which involve cell damage in early stage of exercise and due to temperatures.

Studies on the Iridoid Glycoside and GABA in the Rehmannia glutinosa Cultivars Root

Sang Hoon Lee(이상훈),Jeong Su Yoon(윤정수),Jae Kwang Kim(김재광),Chun Geon Park(박춘근),Mei Lan Jin(김미란),Mok Hur(허목),Seong Cheol Koo(구성철),Woo Moon Lee(이우문),Jae Ki Chang(장재기),Yeon Bok Kim(김연복) 한국약용작물학회 2017 한국약용작물학회 학술대회논문집 Vol.2017 No.2

발레운동과 올리브 잎 추출물 섭취가 중, 노년여성의 항산화 및 면역기능에 미치는 영향

한유선 ( Yu Sun Han ),최도열 ( Do Yourl Choi ),윤정수 ( Jeong Su Yoon ) 한국무용과학회 2013 한국무용과학회지 Vol.30 No.-

본 연구는 발레운동과 올리브 잎 추출물(Olive leaf Standardized)섭취에 따른 항산화효소(SOD), 지방세포단 백질(Adiponectin)과 염증반응지표(IL-6, TNF-α)에 미치는 영향을 규명하여, 중·노년기의 여성의 건강증진에 활용할 수 있는 자료를 제공하고자 하였다. 중·노년(45~70세)여성 45명을 네 집단(발레운동집단15명, 섭취집단10명, 복합처치집단15명, 통제집단5명)으로 구성하여 운동강도 50~70%인 발레운동프로그램에 8주간 참여시킨 후 혈액채취는 실험 전·후로 실시하였다. 항산화효소(SOD), 지방세포단백질(Adiponectin), 인터루킨 -6(IL-6) 그리고 종양괴사인자(TNF-α)측정은 효소면역법(ELISA)를 이용하여 측정하였다. 본 연구의 결과 항산 화효소(SOD)와 지방세포단백질(Adiponectin)의 변화는 운동군과, 섭취군에서 증가하는 경향을 보였으며, 복합처치군에서는 통계적으로 유의하게 증가하는 경향을 보였다. 또한, 인터루킨-6(IL-6), 종양괴사인자(TNF-α)는 모든 실험군에서 감소하는 경향을 보였으며, 특히 운동군에서 통계적으로 유의하게 감소하는 경향을 보였다. 결과적으로 발레운동과 올리브 잎 추출물(Olive leaf Standardized)섭취에 따른 복합처치가 항산화작용의 효과와 더불어 노화예방 및 면역기능 향상에 도움을 줄 수 있을 것으로 사료된다. The objective of this study was to investigate the effects of Ballet exercise program and Olive leaf Standardized supplement on Super Oxide Dismutase(SOD), Adiponectin and inflammatory factor in middle and old aged women. The subjects middle and old aged(45~70) 45 women and they were four groups(Ballet exercise Gymnastics Group :15 Supplement group :10, Complex group :15, Control group :5) and participated intensity HRmax 50~70% of Ballet exercise Gymnastics program for 8 weeks training. Blood sampling were performed before and after. The SOD, Adiponectin, IL-6, TNF-α in the blood were analyzed by the ELISA. In This study result, The SOD and Adiponectin were increased to Ballet exercise Gymnastics Group, Supplement group and significant increased Complex group. In addition, The IL-6, TNF-α were decreased significantly in the all experiment group. but Ballet exercise Gymnastics Group was significant difference in the all experiment groups. In conclusion, the complex treatment effects of Ballet exercise Gymnastics program and Olive leaf Standardized supplement protect the effects of anti-oxidation, anti-aging, immunity.

지구성운동과 Amino acid 병행처치가 위축된 흰쥐 골격근의 재생 및 단백질 합성에 미치는 영향

임채일(Im Chae-Il),고영호(Ko Young-Ho),윤정수(Yoon Chung-Su),김정석(Kim Jeong-Seok),하태균(Ha Tae-Geun) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.3

Purpose : The purpose of this study is to investigate endurance exercise and amino acid supplement induced changes in the expression of Akt, mTOR, myoD, and myogenin in the atrophied rat skeletal muscle by hindlimb suspension. Method : Male Sprague-Dawley rats(n=42) were randomly placed in one of four groups(control, supplement, exercise, supplement&exercise) after 10days atrophy by hindlimb suspension. The Rat in the exercised groups ran the treadmill running for the intensity 30~60min 8~24M/min with degree slope 0°. The Rat in the supplemented groups had oral supplementation of 1ml of Amino acid twice per day(am/pm). The western blotting analysis performed for the expression of Akt, mTOR, myoD, myogenin protein. Results : The expression of Akt significantly increased in one week and gradually decreased in following second and fourth weeks. The expression of mTOR significantly increased in the second week than the first week but decreased in the fourth week. The expression of myoD significantly increased gradually by time passing. The expression of myogenin increased in one week and gradually decreased in following weeks and increased insignificantly in supplemented group. Conclusion : This study can be concluded that combinational treatment with endurance exercise and amino acid supplement has positive effects on recovery of atrophied skeletal muscle by controlling expression of Akt, mTOR, myoD and myogenin involved in protein synthesis and muscle regeneration.

體操選手들의 體力要因 分析

李商鍾,尹正秀 公州大學校스포츠科學硏究所 1988 스포츠科學硏究所論文集 Vol.- No.2

This study was attempted to investigate the physical fitness structure of gymnastic players. The subject included 29 male and 35 female were selected from gymnastics championship. The 10 physical fitness test as discriminators, such as grip strength (right, left), back musscle, chin, 50M dash, sergent jump, side step test, closed eyes foot-balance, shuttle run, truck flexion, long distance running were used. The factor analysis was employed to determine the physical fitness structure. The SPSS computer progrms were used for data analysis. principal factoring with iteration and oblique rotation test were applied for analyzing factor function of 9 physical fitness. The conclusion was that major factors of male gymnastic players were moment movement, muscle strength and flexibility and those of female were grip strength and agility.