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강윤식,장정순,황영실,홍대용,김장락,Kang, Yune-Sik,Jang, Joung-Soon,Hwang, Young-Sil,Hong, Dae-Yong,Kim, Jang-Rak 대한예방의학회 2003 Journal of Preventive Medicine and Public Health Vol.36 No.3
Objective : This study was conducted in order to investigate predictors of smoking cessation in outpatients. Method : Subjects were 40f adult smoking patients who saw their doctors in the outpatient setting at a university hospital, regardless of their willingness of otherwise in smoking cessation. Physicians delivered a brief, stop smoking prompt to all patients who smoked one or more cigarettes a day. Then they referred to on-site counselors who provided a brief, nurse assisted intervention with a survey to a randomly assigned intervention group (200 smoking patients), whom the counselors telephoned later to prevent relapse or promote the motivation to quit, or gave only a survey to a control group (201 smoking patients). After at least 5 months, self-reported current smoking cessation was confirmed later using cut-off values of 7 ppm or less in expired alveolar air after breath holding portable CO analyzer. Results : After 5 months, subjects in the intervention group were 1.56 times (95% C.I. 0.89-2.73) more likely to quit smoking than those in the non-intervention group (14.0% vs. 9.0%). Willingness to quit smoking in a month, scheduled admission in a month, self efficacy score and FTND (Fagerstrom Test for Nicotine Dependence) score were all significantly related with smoking cessation. In stepwise multiple logistic regression, previous attempts to quit smoking were significant instead of self efficacy score. In the intervention group who had willingness to quit smoking in a month (132 smoking patients), FTND score, whether quit date was today, and whether quit promise paper was submitting were all significantly related with smoking cessation. In stepwise multiple logistic regression, scheduled admission in a month and whether quit date was today were significant predictor variables, Smoking cessation treatment should be tailored to individual smoking patients considering these predictors.
방영근,김두경,송환규,권영걸,황영실,박노춘,양웅석 ( Young Keun Bang,Doo Kyung Kim,Hwan Kyu Song,Young Girl Kweon,Young Sil Hwang,Noh Choon Park ) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.1
A clinical analysis was done among 211 cases of advanced stomach cancer which had been confirmed with gastrofiberscopy for 3 years from May, 1977 to September, 1980 at the Depart- ment of Internal Medicine, Yvallace Memorial Baptist Hospital, Busan, Korea The following results were obtained; 1. Among the 211 cases of advanced stomach cancer, 145 cases(68. 72%) were male and 66 cases(31.27%) were female. The ratio of male to female was 2. 2: l. 2. The peak age incidence was in the 5 th decade with 73 cases(34. 59%) and next came the 4 th decade with 54 cases(25, 59%), the 6 th decade with 40 cases(18. 95%) and the 3 rd decade with 27 cases(12. 79%). 3. Among the 173 cases of advanced stomach cancer, 62 cases(35. 83%) were confined to the body of stomach which was the most prevalent site and next came 55 cases(31. 79%) in antrum, 30 cases(17. 34po) in both antrum and body, and 7 cases(4. 04%) in angulus. On the other hand, among the 137 cases, 71 cases(51. 82%) were confined to lesser curvature which was the most prevalent site, and next came 28 cases(20.43%) in greater curvature, 25 cases (18. 24%) in posterior wall, and 13 cases(9. 48%) in anterior wall viewing the stomach laterally. 4. As for the Borrmanns classification in 187 cases, the most frequent was type g with 83 cases and next came type IV with 40 cases, type ]I with 29 cases and type [ with 25 cases in the order. 5 As for the UGI roentgenographic study in 139 cases, stomach cancer was found in 115 cases(82. 73%), benign gastric ulcer in 9 cases(6 47%), gastritis in 6 cases(4. 31%) and norm- al findings in 6 cases(4. 31%). 6. As for the gastrofiberscopic biopsy done in 144 cases, 104 cases(72. 2%) were positive for cancer cell and 40 cases were negative for cancer cell(27. 77%).
비순환기계 중환자의 예후인자로서 Cardiac Troponin I의 유용성
김휘종,함현석,조유지,김호철,이종덕,황영실,Kim, Hwi Jong,Ham, Hyoun Seok,Cho, Yu Ji,Kim, Ho Cheol,Lee, Jong Deok,Hwang, Young Sil 대한결핵및호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.59 No.1
배 경 : cTnI는 심근손상의 특이 표시자로서 급성관상동맥 질환에서 높은 증가는 나쁜 예후와 상관이 있다. cTnI의 증가는 여러 가지 비심장성 중증질환에서도 관찰할 수 있다. 연구자 등은 비순환기계 중환자의 예후인자로서 cTnI의 유용성을 조사하였다. 대상 및 방법 : 2003년 1월부터 2004년 7월까지 경상대학교 병원내과계 중환자실에 급성 관상동맥 증후군 이외의 중증 질환으로 입원한 215명의 환자(남:142명, 여:73명, 평균 나이:$63{\pm}2$세)를 대상으로 하였다. 환자들은 중환자실 입원 24시간 이내에 SAPS II와 SOFA점수를 산출하였고 혈청 cTnI를 측정하였다. cTnI 양성군(${\geq}0.1{\mu}g/L$)과 음성군($<0.1{\mu}g/L$) 환자의 중환자실 제 10병일째와 30병일째 사망률을 비교하였다. cTnI 양성군에서 중환자실 제 10병일째와 30병일째에 혈청 cTnI의 평균수치를 비교하였다. cTnI 양성군에서 혈청 cTnI 수치와 SAPS II와 SOFA점수와의 상관관계를 조사하였다. 결 과 : 1) cTnI양성군 환자는 120명(56%)이었고 음성군환자는 95명(44%)였다. 2) 중환자실 제 10병일째와30병일째의 사망률은 cTnI 양성군(29%, 41%)이 음성군(12%, 21%)보다 유의하게 높았다(p<0.01). 3) cTnI 양성군에서 중환자실제10병일째와 30병일째의 cTnI 평균 수치는 비생존군($4.5{\pm}9.2{\mu}g/L$, $3.5{\pm}7.9{\mu}g/L$)이 생존군($1.8{\pm}3.6{\mu}g/L$, $2.0{\pm}3.9{\mu}g/L$)보다 유의하게 높았다(p<0.05). 4) cTnI 양성군에서 cTnI 수치는 SAPS II 점수(r=0.24, p<0.001)와 SOFA 점수(r=0.30, p<0.001)와 유의한 상관관계가 있었다. 결 론 : 혈청 cTnI는 비순환기계 중환자의 유용한 예후인자가 될 수 있을 것으로 사료된다. Background : Cardiac troponin I (cTnI) is a specific marker of myocardial injury. It is known that a higher level of cTnI is associated with a poor clinical outcome in patients with acute coronary syndrome. An elevation in cTnI is also observed in various noncardiac critical illnesses. This study evaluated whether cTnI is useful for predicting the prognosis in noncardiac critically ill patients. Methods : From June 2003 to July 2004 at Gyeongsang National University Hospital, we enrolled 215 patients (male:142, female:73, mean age:$63{\pm}15$ years ) who were admitted for critical illness other than acute coronary syndrome at the medical intensive care unit(ICU). The severity score of critical illness (SAPS II and SOFA) was determined and serum cTnI level was measured within 24 hours after admission to the ICU. The mortality rate was compared between the cTnI-positive (${\geq}0.1{\mu}g/L$) and cTnI-negative ($cTnI<0.1{\mu}g/L$) patients at the $10^{th}$ and $30^{th}$ day after admission to the ICU. The mean cTnI value was compared between the survivors and non-survivors at the $10^{th}$ and $30^{th}$ day after admission to the ICU in the cTnI-positive patients. The correlation between cTnI and the severity of the critical illness score (SAPS II and SOFA) was also analyzed in cTnI-positive patients. Results : 1) The number of cTnI-negative and positive patients were 95(44%) and 120(56%), respectively. 2) The mortality rate at the $10^{th}$ and $30^{th}$ day after admission to the ICU was significantly higher in the cTnI-positive patients (29%, 41%) than in the cTnI-negative patients (12%, 21%)(p<0.01). 3) In the cTnI-positive patients, the mean value of the cTnI at the $10^{th}$ and $30^{th}$ day after admission to the ICU was significantly higher in the non-survivors ($4.5{\pm}9.2{\mu}g/L$, $3.5{\pm}7.9{\mu}g/L$) than in the survivors($1.8{\pm}3.6{\mu}g/L$, $2.0{\pm}3.9{\mu}g/L$) (p < 0.05). 4) In the cTnI-positive patients, the cTnI level was significantly correlated with the SAPS II score (r=0.24, p<0.001) and SOFA score (r=0.30, p<0.001). Conclusion : The cTnI may be a useful prognostic marker in noncardiac critically ill patients.