맞춤식품의 현재와 미래; 식품개발에서의 영양유전체학 및 개인별 맞춤영양학의 적용

홍경희(Kyung-Hee Hong) 한국식품영양과학회 2007 식품산업과 영양 Vol.12 No.2

수용액 중에서 Ni(II) 이온과 2-(2-Hydroxyethylamino)-2-(hydroxymethyl)-1,3 -propanediol(Monotris)과의 착물형성에 대한 연구

홍경희(Hong, Kyung-Hee),심승보(Shim, Seung-Bo),오성근(Oh, Seong-Geun),전용진(Chun, Yong-Jin) 한국산학기술학회 2010 한국산학기술학회논문지 Vol.11 No.12

Ni(II)이온과 2-(2-Hydroxyethylamino)-2-(hydroxymethyl)-1,3-propanediol(Monotris)과의 착물형성을 25℃ 이온강 도 0.10M 에서 전위차법으로 연구하였다. NiL<SUP>2+</SUP> 착물은 히드록실기의 산소 원자 뿐만아니라 아민의 질소기도 금속에 배위하였다. pH가 증가하면서 NiL<SUP>2+</SUP>=는 3개의 수소이온이 해리된 Ni2L2H-3<SUP>+</SUP>의 이핵착물이 형성되었다. The complex formation from Ni(II) ion and 2-(2-Hydroxyethylamino)-2-(hydroxymethyl)-1,3-propanediol (Monotris) in aqueous solution at 25℃ and at ionic strength of 0.10M has been studied potentiometrically. In the Monotris(L) comlex NiL<SUP>2+</SUP> , hydroxyl oxygen atom as well as the amine nitrogen of the ligand are coordinated to the Ni(II) ion.. The complex NiL<SUP>2+</SUP> undergoes further dissociation as the pH is increased forming triply deprotonated dinuclear complex Ni2L2H-3<SUP>+</SUP> + .

단위가축영양 : Miniature Poodle에 있어서 현미 함유사료의 영양소 소화율 및 배설 분 특성

홍경희 ( Kyung Hee Hong ),오영균 ( Young Kyoon Oh ),이상락 ( Sang Rak Lee ),소경민 ( Kyoung Min So ),문상호 ( Sang Ho Moon ),박창석 ( Chang Seok Park ),이경원 ( Kyung Won Lee ),김경훈 ( Kyoung Hoon Kim ) 한국동물자원과학회(구 한국축산학회) 2012 한국축산학회지 Vol.54 No.5

본 연구는 반려견 사료 내 주요 탄수화물원인 밀가루 (원물기준 약 51%)를 현미로 15%, 30% 대체 급여하였을 때, 사료의 소화율 및 배설 분의 특성 변화를 조사하기 위하여 Miniature Poodle (8~9개월령, 평균 3.5kg) 6마리를 이용 반복 3 × 3 라틴방각법에 따라 실험을 수행하였다. 건물 섭취량과 유기물섭취량이 현미수준 증가에 따라 linear하게 감소 (P<0.05)되었는데, 총에너지 섭취량은 15%구에서 가장 낮은 quadratic 효과 (P=0.07)가 나타났다. 현미 대체에 의해 건물, 유기물, 조단백질, 산분해 지방, 에너지 소화율 이 linear (P<0.05)하게 증가하였다. 사료의 가소화에너지 및 대사 에너지 농도 (kcal/kg DM)도 현미 대체 비율이 증가하면서 linear 하게 증가 (P<0.001, P=0.007)하였다. 생분 배설량과 건조 분량도 모두 linear(P=0.001)하게 감소하였다. 분 score도 linear하게 감소 (P<0.05)하게 감소하였지만, 분 암모니아 농도는 현미대체 비율이 증가 할수록 linear하게 증가 (P<0.05)하였다. 분 암모니아 증가는 linear하게 감소 (P<0.01)한 short?chain fatty acid 농도와도 관계 가 있을 것으로 판단된다. 본 실험의 결과, 현미급여가 반려견의 소화율과 배설 분의 특성을 개선해 주는 것으로 나타났다. In this experiment, two inclusion levels (15 and 30% of diets, as-fed basis) of brown rice (BR) were tested against a control diet with 0% BR (51% wheat flour of diet). Six female Miniature Poodles (8~9 months age, initial mean body weight of 3.5 kg) were assigned to treatments in replicated 3×3 Latin square design. Total tract digestibilities of DM, OM, CP, acid hydrolyzed fat and gross energy increased linearly (P<0.05), and observed digestible energy and metabolizable energy values also increased linearly (P<0.001 and P=0.007, respectively) with increasing BR inclusion levels. Wet and dry fecal output decreased linearly (P=0.001) with increasing BR inclusion levels in the diets. Linear (P<0.05) effects was observed in fecal score for dogs fed BR and fecal ammonia concentration increased linearly (P<0.05) in response to increasing BR inclusion level. It seems that the increase in fecal ammonia concentration may be partially related to the decrease in short-chain fatty acid concentration (P<0.01). This study clearly demonstrates that BR improves nutrients digestibility and fecal characteristics of dog.

보문 : 여성 노년층 소비자의 라이프스타일 유형에 따른 판매원 속성 중요도와 의류 점포평가기준 -서울지역 거주 60-70대 여성을 중심으로

홍경희 ( Kyung Hee Hong ),이윤정 ( Yoon Jung Lee ) 韓國衣類學會 2009 한국의류학회지 Vol.33 No.11

금속장신구에 나타난 섬유 기법 연구

홍경희(Hong, kyung-hee),김정지(Kim, jung-ji) 한국조형디자인학회 2006 조형디자인연구 Vol.9 No.2

This research is written on the topics related to various kinds of weaving methods used in personal ornaments, unlike the traditional metal techniques. Along with the study about the data able to use as a historical basis, I tried to set the basic research background on the development of the fabrication in metal products in its actual use and value. Also, I have considered different kinds of expressing methods to analyze and organize the fabrication used for contemporary jewelry, and studied applicable examples related to its specialty in industry. The result of the research showed that the fabrication method based upon the historical metal ornaments relics affected the fabrics and the metal methods which existed at the same time based upon the personality of the area and its decade, rather than being classified by its historical cultural background, development of the techniques or its relations clearly. However, contemporary artists are applying textile techniques in metals with active attitude, challenging for the new methods and shapes, to be able to express their own creativity. The industries have diversity of products using the strength in metal material's permanence and fabric organizing method. Especially nowadays, the way of mixing the metal and fabric has been diversified with the development of technology, and throughout this, development in continuous new materials will give endless possibility to creative sculptures. As you can see, understanding the mixture of materials and technology as well as the cultural human value and its historical background will help to build new researches on developing new metal cultural contents.

장신구트렌드 분석을 통한 디자인 개발시스템방안 연구

홍경희(Hong, kyung hee) 한국조형디자인학회 2006 조형디자인연구 Vol.9 No.1

Korea has solidified its position in various areas including high ‐tech industries such as semiconductor and IT but the domestic jewelry industry is losing competitiveness against imported brands before it grows because the design of its jewelry products is inferior in international sense. As for the current situation of the domestic jewelry industry, although it is high value‐added business, governmental support and investment by large enterprises are insignificant, and most jewelry businesses are small in size except a few companies. In this situation, it is hard to make planned investment in developing designs although the important of design is well recognized. As a consequence, identity for design has not been established and most designs are short‐sighted and temporary without creating high value added. A breakthrough of the jewelry industry for this problem is developing designs reflecting consumers’ sensibility and product trends like many outstanding companies in Korea and other countries develop products in response to future consumers’ rapidly changing desires through analyzing product trends. Trends in an industry cannot be read by a single factor. Likewise, trends in the jewelry industry are formed through organic interaction among issues such as politics, economy and society as well as cultural factors such as people’s mind, the pattern of life, the pattern of leisure activities, job preference, color preference and lifestyle. As for research on jewelry trends in Korea, available information in Korea are at best newspaper articles that quote materials from exhibitions in overseas. On the contrary in other countries, research institutes specialized in markets forecast future trends and suggest new trends, and then media related to jewelry analyze and introduce the trends, and companies develop products of new designs and display new trend jewelries that will lead the fashion in various fairs. Thus, the present study purposed to propose an operating system for developing design through analyzing trends in various areas. The system is designed to read jewelry trends from a generally acceptable view by combining materials from research institutes in different areas, collecting information on factors related to trend formation, visualizing factors with which trends can be forecasted, deriving keywords for jewelry trends, creating trend maps, and holding forums for the exchange of opinions with specialists in relevant areas. Next, the system will publish trend reports and trend books for jewelry businesses and designers to present future jewelry trends and provide a long view to jewelry trends. For the effective propagation of analyzed jewelry trends, it is considered desirable to have explanatory meetings for jewelry companies, designers and jewelry design students, give them the understanding of factors and mechanism of trend formation, and suggest the applicability, possibility, application cases and product images of various materials and forms. In addition, in order for jewelry trends to be practically utilized in design, we need to conceptualize presented images, adopt them as themes for design development, and open design contests. Designs selected in such contests can produced by cooperative companies and exhibited in fairs or fashion shows, and these activities will enhance the recognition of next generation ‐ jewelry trends and the objectivity of jewelry design. The jewelry design development system based on trend analysis can change the ideas of designers and related companies through the presentation and education of trends, raise the companies’ sales revenues by supplying high‐quality jewelry designs, create Korean‐unique brands reflecting local characteristics by reading cultural trends, and globalize the domestic jewelry industry by understanding the culture of countries that import our jewelry products.

금속의 탄성을 이용한 유기적 연결구조의 장신구 조형 연구

홍경희(Hong, Kyung-hee),이주현(Lee, Ju-hyun) 한국조형디자인학회 2015 조형디자인연구 Vol.18 No.3

현대 장신구는 다양한 재료와 기법의 사용으로 크기와 형태의 제약에서 벗어나 그 자체의 조형성을 표현함으로써 조형예술의 한 분야로 인정받고 있다. 그러나 과거부터 장신구의 주된 재료로 사용되었던 금속은 타 재료보다 비교적 무거운 무게와 접합방식의 어려움으로 인하여 현대 장신구의 분야에서 그 사용 범위가 줄어들고 있다. 그럼에도 불구하고 금속은 광택이 미려하며 타 재료와 비교하여 강도와 탄성도가 우수한 재료학적 특성이 있어 장신구 재료로써 사용하기에 큰 장점이 있다고 할 수 있다. 이에 본 연구는 이러한 금속의 이점을 살리어 타 재료로 표현하기 어려운 선의 탄성을 이용한 형태의 장신구를 제작하고자 한다. 또한, 장신구의 조형성을 확보하기 위해 선의 유기적 연결구조를 이용한 제작방식을 연구하며 탄성에 의한 리듬감과 반복적 구성의 공간감 및 유닛에 의한 확장성을 조형적으로 표현하고자 한다. 금속 중에서도 스테인리스 스틸은 다른 금속에 비하여 비중이 작은 편에 속하며 탄성과 강도, 내식성이 뛰어난 특성이 있어 본 연구 결과물의 재료로 선택하였다. 선재로 가공한 스테인리스 스틸을 금속관절 유닛과 유기적으로 연결하는 콜드조인트(cold-joint)방식을 사용하여 장신구의 무게를 줄임과 동시에 탄성의 효과를 극대화하며 접합방식의 비효율성을 해결하고자 하였다. 또한, 조형적 완성도를 높이기 위해 황동관절 유닛의 여닫는 부분을 뒷장식으로 활용하여 시각적으로 드러나는 기능적 요소를 제거해 조형미를 살리고자 하였다. 형태적 특성은 스테인리스 스틸 선의 결합의 방식에 따라 크게 두 가지로 나누어 볼 수 있다. 첫 번째 디자인은 단순한 선의 흐름에 따른 조화를 통해 선과 인체의 관계를 중점으로 표현하고자 하였으며 두 번째 디자인은 선의 반복적인 유닛의 연결을 통해 그 자체의 유기적 구성을 중점으로 표현하고자 하였다. 두 가지 디자인 모두 장신구 내부에서 혹은 외부와의 관계에서 상호 간의 유기적인 조화를 이루는 공통점을 공유하였다. 본 연구의 결과물은 선의 탄성을 통한 유기적 연결로 인해 착용자의 움직임에 따라 그 형태가 변화하여 착용감의 우수함이 나타났다. 그리고 유닛과 선의 반복적인 연결로 장신구의 형태 확장이 용이하기 때문에 크기와 형태 면에서 제약이 없는 특성이 나타났다. 또한, 기능적 요소인 뒷장식의 형태를 관절 유닛의 형태와 일치시킴으로써 높은 수준의 조형적 완성도를 구축할 수 있었다. 본 연구를 통하여 기존 금속의 한계를 벗어나 장신구의 조형성을 더하는 성과를 얻을 수 있었다. 이를 기반으로 하여 장신구의 분야를 넘어선 조형분야와의 소통이 활성화되기를 바란다`. Modern jewelry is recognized as a part of the formative arts, with various materials and skills used that deviate from the limits of size and type and express formativeness itself. In contrast, metal, which has been used as a main material for jewelry for a long time, is losing its position in the field of modern jewelry due to the inefficiency of its relatively heavy weight and connection methods compared with other materials. Metal has benefits for use as a material for jewelry because of its elegant gloss and excellent strength compared with other materials. Therefore, this study examined a production method of an organic linking structure in order to secure the formativeness of jewelry by using the elasticity of the metal. In addition, the formativeness of jewelry was studied in terms of a sense of rhythm through elasticity and a sense of space of repetitive composition and expansion of a unit. Stainless-steel has a small specific gravity compared with other metals and has the excellent characteristics of corrosion resistance for selection as the material of this study. In addition, in order to solve the weight problem and the inefficiency of the connection method and maximize the effects of tension, an organic linking method by cold-jointing that connects the metal wire by the metal joint-unit was used. To improve formative completeness, the brass joint unit was utilized as a pin to emphasize the aesthetic value of the jewelry by removing visible functional factors. The external characteristics of the form can be largely divided into two according to the combination of lines. The first design was focused on the relationship between the line and the human body in terms of harmony according to the flow of a simple line, and the second design focused on organic composition through a connecting repetitive unit of a line. Both the designs had something in common regarding organic harmony in the relationship inside or outside the jewelry. The results of this study demonstrated excellence in terms of changing shapes according to the movements of a wearer due to the organic connection through the elasticity of the line. Because of the easy expansion of the structure from the repetitive connection of a unit and line, its characteristics are not limited in the aspects of size and shape. Moreover, formative completeness was implemented at a high level by coinciding the shape of the pin as a functional factor with the joint unit. This study could contribute to the formativeness of jewelry by deviating from the existing limits of metal. Based on this, it is hoped that communication between the jewelry field and the formative field will be revitalized.

피부섬유아세포에서 저산소증에 의한 Connective Tissue Growth Factor의 발현

홍경희 ( Kyung Hee Hong ),유승아 ( Seung Ah Yoo ),강순숙 ( Soon Sook Kang ),신용주 ( Yong Ju Shin ),김완욱 ( Wan Uk Kim ),조철수 ( Chul Soo Cho ) 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.4

Objective: Connective tissue growth factor (CTGF) has been proposed to play a role in fibrotic process of systemic sclerosis. Since hypoxia was known to be associated with fibrosis in several profibrogenic conditions, we investigated whether CTGF expression in dermal fibroblast is regulated by hypoxia caused by microvascular loss. Methods: Dermal fribroblasts from patient with systemic sclerosis and normal controls were cultured in the presence of cobalt chloride (CoCl2), a chemical inducer of HIF-1α or hypoxic culture conditions. Expression of HIF-1α, VEGF and CTGF was evaluated by semiquantitative reverse transcription-polymerase chain reaction and Western blotting. Results: Scleroderma fibroblasts expressed increased levels of HIF-1α, VEGF and CTGF compared to normal dermal fibroblasts. Dermal fibroblasts exposed to various concentration of CoCl2 (1∼100μM) enhanced the expression of CTGF mRNA in dose-dependent fashion. Actinomycin D significantly blocked the hypoxia-mediated up-regulation of CTGF mRNA expression, whereas cycloheximide did not block the up-regulation. Up-regulation of CTGF by hypoxia was not mediated by endogenous production of transforming growth factor (TGF)-β. In time-kinetics study, dermal fibroblasts from scleroderma patients exhibited earlier peak expression of CTGF mRNA than those from normal dermal fibroblasts. In addition, simultaneous treatment of suboptimal concentration of CoCl2 and TGF-β exhibited the up-regulation of CTGF mRNA in additive fashion. Interferon-γ did not modulate the expression of CTGF mRNA induced by CoCl2, while the up-regulation of CTGF by TGF-β was downregulated by Interferon-γ in a dose-dependent fashion. Conclusion: These data indicate that hypoxia up-regulates the expression of CTGF in dermal fibroblasts and provide the evidence that hypoxia caused by microvascular alterations contributes the progression of fibrosis in systemic sclerosis by up-regulation of CTGF.

알루미늄을 활용한 장신구 연구

홍경희(Hong, Kyung-hee),홍지선(Hong, Ji-sun) 한국조형디자인학회 2010 조형디자인연구 Vol.13 No.3

인류 문명의 발전과 더불어 발달해온 것 중 하나는 장신구로서 각 시대별 문화와 환경에 의하여 독창적인 양식으로 표현되어 왔다. 귀금속 장신구에 비하여 짧은 역사를 지난 알루미늄 장신구는 각 연대별로 발전과 침체의 과정을 거쳐 현재에 이르고 있다. 알루미늄 대량생산이 시작되면서 장신구 재료로의 사용이 감소하고 일상생활 분야로 확대되는 계기를 맞이한다. 알루미늄 재료의 가치가 하락함에 따라 대중적인 장신구 재료로 다양하고 개성 있는 표현 양식으로 발달되어 현재에 이르고 있다. 본 연구는 알루미늄 발달과 역사, 장신구 재료로서 알루미늄에 관한 특징과 종류 및 장단점을 살펴보고, 알루미늄 장신구 제작에 필요한 성형 및 가공방법을 토대로 그 가공법의 응용 순으로 연구되었다. 현대 금속 장신구 분야에서 알루미늄 장신구의 미래와 실험적인 조형표현의 가능성과 다양성을 제시하고자 한다. Accessories are one of items that have been developed with human civilization process and they have been expressed as a unique form of style by the culture and the environment of each era. Aluminum accessories with relatively shorter history compared to the jewelry accessories survived through the process of development and stagnation by era to the present. As the aluminum mass production started, its use as accessory materials reduced and it became a chance to expand the use of aluminum to the field of everyday life. As the value of aluminum as a materials dropped, it also has been developed as a various and unique expression of style as popular accessory materials to the present. This study looked at the development and the history of aluminum, the characteristics, types and the pros and cons of aluminum, and based on the forming and processing methods required for the aluminum accessory production, researched the practical application of the processing method in turn. It is intended to suggest the furniture of the aluminum accessories. the functionality of experimental shaping methods and the diversity of shaping and modeling in the modern metal accessory fïeld.

유,아동 의류 제품의 세탁과 관련된 소비자 피해 사례 및 불평 행동 연구

홍경희 ( Kyung Hee Hong ),이윤정 ( Yoon Jung Lee ) 복식문화학회 2007 服飾文化硏究 Vol.15 No.1