장애아전문어린이집 보육교직원들의 아동권리존중에 대한 인식과 실행

홍경자(Hong, Kyoung-Ja),안영혜(An, Young-Hye),홍순옥(Hong, Soon-Ohk) 한국영유아보육학회 2015 한국영유아보육학 Vol.0 No.94

본 연구는 장애아전문어린이집 보육교직원의 아동권리존중 교육에 대한 인식과 실행을 살펴봄으로써 장애아동 권리존중보육을 위한 기초자료를 제공하는데 목적을 두고, P시의 장애아전문어린이집에 현재 근무하고 있는 보육교사, 유아특수교사, 치료사를 대상으로 설문조사와 심층면담을 실시하였다. 수집된 자료는 PASW 18.0 프로그램을 이용하여 대응표본 t검증, 일원변량분석, Scheffe 사후검증을 통해 분석하였고, 심층면담자료는 전사한 후 코딩(coding), 분류, 범주화 과정을 통해 분석하였다. 이에 따른 연구결과를 살펴보면, 첫째, 장애아전문어린이집 보육교직원들의 아동권리존중에 대한 인식과 실행 간에는 유의한 차이가 있었다. 둘째, 장애아전문어린이집 보육교직원들의 직무유형에 따른 아동권리존중 영역별 하위내용에 대한 인식의 차이는 전체에서 통계적으로 유의한 차이가 있었고, 이에 대한 사후검증 결과 보육교사와 치료사 간에 유의한 차이가 있었다. 셋째, 장애아전문어린이집 보육교직원들은 사회적 편견을 가지지 않는 것이 장애아동의 권리존중이라는 인식을 가지고 있었고 실생활 중심, 흥미중심, 개별적 발달수준, 지역사회 문화행사 참여, 다양한 경험을 통한 교육을 중심으로 보육을 실행하고 있었으며, 장애아동의 다양한 발달적 특성의 차이, 자율성 허용범위와 지도를 위한 훈육 사이에서의 혼란, 사회적 편견으로 인한 지역사회참여 기회 및 아동권리존중 보육에 대한 지식부족 등으로 어려움을 가지고 있었으며, 장애아동에 대한 인식개선 및 이를 위한 홍보, 다양한 아동권리 존중교육을 받을 기회제공, 사회적 참여 기회의 확대 등이 필요하다고 인식하고 있었다. The purpose of this study was to offer basic data for the education of respecting disabled children"s rights by examining the recognition and the implementation of the education of respecting disabled children"s rights in disability-specialized early childhood teachers. A questionnaire survey and an in-depth interview were carried out targeting day care teachers, early childhood special education teachers, and therapists who are now working at a specialized child care center for children with disabilities in P city. The collected data were analyzed through paired sample t-test, one-way ANOVA, and Scheffe"s post hoc test by using the PASW 18.0 program. The in-depth interview materials were analyzed through the process of coding, classifying and categorizing after transcription. The findings are as follows. First, it was shown that there is significant difference (t=7.87, p<.001) between the recognition (M=4.00, SD=1.07) and implementation (M=3.49, SD=1.05) of respecting children"s rights in disability-specialized early childhood teachers. Second, the difference in the recognition of the sub-contents by sphere of respecting children"s rights according to the role of disability-specialized early childhood teachers had statistically significant difference on the whole (t=4.69, p<.05). As a result of the post-test on this, there was significant difference between day care teachers and therapists. However, the difference in implementation had no statistically significant difference in all the spheres of the whole and the sub-factors by sphere of children"s rights. Third, the disability-specialized early childhood teachers showed their recognition by saying that respect for the rights of disabled children is not to have social prejudice rather than specially a right for disabled children as for “disabled children"s rights.”(I am not sure what this means.) Even the child-care practice contents of respecting children"s rights were being executed by focusing on the real lives of the disabled children, their interests, their individual development levels, their participation in community cultural events, and their education through diverse experiences. Disabled children’s difficulties generally stemmed from the difference in their diverse developmental characteristics, confusion between the range of allowing autonomy and the discipline for guidance, opportunities to participate in the community due to social prejudice, and the lack of knowledge of childcare related to respecting children"s rights. It was found that it was necessary to to increase the awareness of disabled children, to create positive publicity for this, to offer opportunities of receiving education on respecting children"s diverse rights, and to expand disabled children"s opportunities to engage in social participation.

에탄올 유래 세포사망 : bcl-2 proto-oncogene에 의한 세포사망 저해

임은정,홍경자,양병환,채영규,Lim, Eun-Jeong,Hong, Kyoung-Ja,Yang, Byung-Hwan,Chai, Young-Gyu 대한생물정신의학회 1997 생물정신의학 Vol.4 No.2

The Bcl-2 protein has been shown to block apoptosis induced by a variety of stimuli. We have performed the experiments which cell death can be blocked by the bcl-2 proto-oncogene under moderate(50-100mM) or high ethanol treatment(400-600mM). As a result of morphological changes, and MTT assay, cell death was blocked by Bcl-2 under 100mM ethanol. However, the results of DNA fragmentation and RT-PCR(ICE, and CPP32), immunoblotting(CPP32, and PARP) for SK-pcDNA3 cells(vector only) and SK-Bcl-2 cells(stably expressed bcl-2 gene) were showen to be no significant differences between two cell lines. These results suggested that cell death induced by ethanol was not followed by apoptosis mechanism, and was blocked by the bcl-2 proto-oncogene with moderate ethanol.

Role of Calcium in Function of Isolated Perfused Rabbit Kidney

이권행,전은의,홍경자,조규철,Lee, Kweon-Haeng,Chun, Eun-Eui,Hong, Kyoung-Ja,Cho, Kyu-Chul The Korean Society of Pharmacology 1986 대한약리학잡지 Vol.22 No.2

저자는 적출관류 토끼 신장기능에서 칼슘의 역할과 furosemide의 이뇨작용에 미치는 영향을 관찰하여 다음과 같은 결과를 얻었다. hydralazine놔 verapamil을 주로 신혈관 저항의 감소로 이뇨작용을 나타냈다. furosemide를 hydralazine 또는 verapamil 병합투여시 뚜렷한 이뇨작용이 나타났으며 두군 사이에 차이는 없었다. quinidine은 신혈관 수축을 일으켰으나 이뇨작용이 나타났으며 furosemide의 이뇨작용을 항진시켰다. 칼슘제외된 관류액으로 관류시 칼슘은 신혈관 수축에도 불구하고 이뇨작용이 나타났으며 furosemide의 이뇨작용을 항진시켰다. quinidine은 칼슘이 제외된 상태에서 신장기능 및 furosemide의 이뇨작용에 영향을 미 치지 못하였으나 calcium 병합투여시 과도한 신혈관 수축으로 항 이뇨작용을 보였다. verapamil은 칼슘이 제외된 상태에서 약간의 이뇨작용을 보였지만 칼슘 및 furosemide의 이뇨작용을 변화시키지 못하였다. 이상의 성적은 적출관류 토끼 신장에서 칼슘, verapamil 및quinidine이 이뇨작용이 있으며 칼슘은 furosemide의 이뇨작용을 항진시킨다. This study was designed to investigate the role of calcium in the function of an isolated perfused rabbit kidney and its effect on the diuretic action of furosemide. The administrations of hydralazine and verapamil produced remarkable diuretic actions mainly by decreasing renal resistance. The administration of furosemide in combination with hydralazine or verapamil produced remarkable diuretic action and there was no difference between the two groups. The administration of quinidine produced a diuretic action in spite of vasoconstriction and potentiated the diuretic action of furosemide. In the calcium-free perfusion medium, the administration of calcium produced a marked diuretic action in spite of vasoconstriction and potentiated significantly the diuretic action of furosemide. The administration of quinidine did not alter renal function and the diuretic action of furosemide, but the combined administration of quinidine and calcium showed antidiuretic effect due to excessive vasoconstriction in the calcium-free perfusion medium. Although the administration of verapamil produced a slight diuretic action in the calcium-free perfusion medium, verapamil did not alter the diuretic action of calcium as well as the diuretic actions of furosemide alone and in combination with calcium. The results of this experiment show that calcium, verapamil and quinidine produced diuretic actions and calcium potentiates the diuretic action of furosemide.

장애유아 아버지의 양육참여도와 어머니의 양육스트레스, 행복감과의 관계 및 영향

안영혜(An, Young-Hye),홍순옥(Hong, Soon-Ohk),홍경자(Hong, Kyoung-Ja) 한국영유아보육학회 2016 한국영유아보육학 Vol.0 No.96

본 연구의 목적은 장애유아 자녀를 둔 아버지의 양육참여도와 어머니의 양육스트레스, 행복감과의 관계를 살펴봄으로써 장애유아 아버지의 양육참여도가 어머니의 양육스트레스와 행복감에 어떠한 영향을 미치는지 알아보기 위함이다. 본 연구는 부산광역시에 소재한 장애전문 어린이집에 현재 다니고 있는 장애유아 부와 모 482명을 연구대상으로 하였다. 본 연구를 위해 수집된 자료는 SPSS 22.0을 이용하여 Pearson의 적률상관계수, 중다회귀분석을 실시하였다. 이에 따른 연구결과는 다음과 같다. 첫째, 장애유아 아버지의 양육참여도와 어머니의 양육스트레스 간에 부적 상관관계가 있는 것으로 나타났으며 양육참여도 하위요인 중 함께하는 활동, 양육자로서의 책임감이 양육스트레스에 영향이 있는 것으로 나타났다. 둘째, 장애유아 아버지의 양육참여도와 어머니의 행복감 간에 정적 상관관계가 있는 것으로 나타났으며 양육참여도 하위요인 중 함께하는 활동, 양육자로서의 책임감이 행복감에 영향이 있는 것으로 나타났다. 셋째, 장애유아 어머니의 양육스트레스와 행복감간에 부적 상관관계가 나타났으며 양육스트레스 하위요인 중 부모의 고통, 까다로운 아동이 행복감에 영향을 미치는 것으로 나타났으나 부모-아동 역기능적 상호작용은 영향을 미치지 않는 것으로 나타났다. The purpose of this study was to examine the relationship of paternal participation to maternal stress and happiness in parents of disabled preschoolers in an effort to determine the impact of the former on the latter two. The subjects in this study were 241 fathers and 241 mothers whose disabled children attended daycare centers for the disabled located in the city of Busan. The instruments used in this study were a productive paternal role scale (Lee et al., 1998), an abridged form of a Korean version of parental stress inventory (Lee et al., 2008) and a happiness scale (Roh, 2013). The collected data were analyzed by the statistical package SPSS 22.0, and Pearson product-moment correlation coefficients and multiple regression analysis were utilized. The findings of the study were as follows: First, there was a negative correlation between the paternal participation of the fathers who had young disabled children and the maternal stress of the mothers. Among the subfactors of paternal participation, joint activities and a sense of responsibility as a rearer exerted an influence on maternal stress. Second, there was a positive correlation between the paternal participation of the fathers and the maternal happiness of the mothers. Among the subfactors of paternal participation, joint activities and a sense of responsibility as a rearer had an impact on maternal happiness. Third, there was a negative correlation between the maternal stress and happiness of the mothers. Among the subfactors of maternal stress, happiness was under the influence of parental pain and fastidious young children, and dysfunctional parent-child communication exercised no influence on that.

적출관류 토끼 신장기능에서 칼슘의 역할

이권행(Kweon-Haeng Lee),전은의(Eun-Eui Chun),홍경자(Kyoung-Ja Hong),조규철(Kyu-Chul Cho) 대한약리학회 1986 대한약리학잡지 Vol.22 No.2

저자는 적출관류 토끼 신장기능에서 칼슘의 역할과 furosemide의 이뇨작용에 미치는 영향을 관찰하여 다음과 같은 결과를 얻었다. hydralazine놔 verapamil을 주로 신혈관 저항의 감소로 이뇨작용을 나타냈다. furosemide를 hydralazine 또는 verapamil 병합투여시 뚜렷한 이뇨작용이 나타났으며 두군 사이에 차이는 없었다. quinidine은 신혈관 수축을 일으켰으나 이뇨작용이 나타났으며 furosemide의 이뇨작용을 항진시켰다. 칼슘제외된 관류액으로 관류시 칼슘은 신혈관 수축에도 불구하고 이뇨작용이 나타났으며 furosemide의 이뇨작용을 항진시켰다. quinidine은 칼슘이 제외된 상태에서 신장기능 및 furosemide의 이뇨작용에 영향을 미 치지 못하였으나 calcium 병합투여시 과도한 신혈관 수축으로 항 이뇨작용을 보였다. verapamil은 칼슘이 제외된 상태에서 약간의 이뇨작용을 보였지만 칼슘 및 furosemide의 이뇨작용을 변화시키지 못하였다. 이상의 성적은 적출관류 토끼 신장에서 칼슘, verapamil 및quinidine이 이뇨작용이 있으며 칼슘은 furosemide의 이뇨작용을 항진시킨다. This study was designed to investigate the role of calcium in the function of an isolated perfused rabbit kidney and its effect on the diuretic action of furosemide. The administrations of hydralazine and verapamil produced remarkable diuretic actions mainly by decreasing renal resistance. The administration of furosemide in combination with hydralazine or verapamil produced remarkable diuretic action and there was no difference between the two groups. The administration of quinidine produced a diuretic action in spite of vasoconstriction and potentiated the diuretic action of furosemide. In the calcium-free perfusion medium, the administration of calcium produced a marked diuretic action in spite of vasoconstriction and potentiated significantly the diuretic action of furosemide. The administration of quinidine did not alter renal function and the diuretic action of furosemide, but the combined administration of quinidine and calcium showed antidiuretic effect due to excessive vasoconstriction in the calcium-free perfusion medium. Although the administration of verapamil produced a slight diuretic action in the calcium-free perfusion medium, verapamil did not alter the diuretic action of calcium as well as the diuretic actions of furosemide alone and in combination with calcium. The results of this experiment show that calcium, verapamil and quinidine produced diuretic actions and calcium potentiates the diuretic action of furosemide.

가정·방문간호 수요추계

박정호(Jeong Ho Park),윤순녕(Soon Young Yun),김매자(Mae Ja Kim),한경자(Kyoung Ja Han),홍경자(Kyoung Ja Hong),박성애(Seong Ae Park),허정순(Jeong Soon Heo) 한국간호행정학회 2002 간호행정학회지 Vol.8 No.4

한국인의 2중합효소연쇄반응-증폭 좌위에 대한 동위 유전자 빈도 분포

홍경자,백승연,채영규 한양대학교 이학기술연구소 2000 이학기술연구지 Vol.2 No.

Tetranucleotide STR인 HUMTH01과 HUMF13A1에 대한 대립형질과 유전형질 빈도를 한국인을 대상으로 전기영동 및 중합효소연쇄반응을 이용하여 분석하였다. HUMTH01과 HUMF13A1 유전형질 분포 양상은 Hardy-Weinberg 공식을 따랐다. 부가적으로 한국인 집단의 대립형질 빈도를 중국인과 유럽코커시안 집단의 데이터와 비교하였다. 코커시안집단에서 HUMTH01의 분포양상은 유사하였다. 하지만 한국인과 중국인 집단의 결과와 유사하였다. 본 연구에서 HUMTH01과 HUMF13A1 STR 좌위에 대한 한국인 집단 데이터베이스를 확립하였다. 이들 집단에서 STR의 대립형질빈도 분포 데이터는 인간집단유전학을 위한 연구에 유용하게 사용될 수 있을 것이다. Allele and genotype frequencies for the tetranucleotide STRs (short tandem repeats) of HUMTH01 and HUMF13A1 were investigated in Korean population using electrophoresis and PCR amplification. The HUMTH01 and the HUMF13A1 genotype distributions were in Hardy-Weinberg equilibrium. Additionary, the allele frequencies of Korean population were compared with data for the Chinese population and European Caucasian populations. There were similar distribution patterns of HUMTH01 allete frequencies among the Caucasian populations. However, Korean and Chinese populations were significantly different with them. Allele distribution pattern of Korean was more similar with Chinese population than them of European. Conclusively, the Korean population database has been established for HUMTH01 and HUMF13A1 STR loci. These data of allele frequencies distribution of STRs in population will be useful for studies on human population genetics.

질의응답을 중심으로 본 의약정보 제공의 질 평가

박창선,홍경자 한국병원약사회 1999 병원약사회지 Vol.16 No.2

The purpose of Medication Information is to promote proper use of medication through which a improvement of the quality of life is assured. Medication Information should be patient specific and offered with responsibility as an integral part of Pharmaceutical Care. The quality of Medication Information on Q&A is evaluated using the explicit written criteria, giving 1 to 4 points in 10 categories and converted to 100% at Drug Information Center of Kangnam St. Mary's Hospital, between Oct. 1995 to Sept. 1998. As a result, the total average score showed a little differences every year and the highest score (92.7) was time frame while the follow-up score was the lowest (49.5) and others were above 93.8. These results indicate that the technique how to draw the background information from the requester should be emphasized and taught at training and time should be give for follow-up.

간호정보 검색방법 탐구 : Internet 및 CD-ROM 등을 기본으로

서문자,한경자,최명애,김정은,홍경자,박성애,이명선 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.11 No.2

The purpose of this study was to explore how to access nuring information using computer and other softwares. It described the ways to reach and get the database on abstracts of masters' and doctoral dissertations in nursing and medicine in Korea. It also provided the ways to get nursing related database around the world, such as Medline, using internet search tools. Internet search tools included databases and their themes and unique characteristics. In addition, the study illustrated the ways to use netscape navigator using LAN or modem and to use CINAHL-CD-Rom title which is commonly utilized in nursing. The results of this study might help nurses and nursing scholars efficiently access the needed information and database which can be utilized in education and research areas.

노랑초파리종군의 발생단계에 따른 단백질의 변화와 유전적 유연관계 : SDA - PAGE 에 의한 수용성 단백질의 분석 Analysis of Soluble Protein by SDS - PAGE

이택준,홍경자,송은숙 한국유전학회 1993 Genes & Genomics Vol.15 No.4

Soluble protein in eight species of the Drosophila melanogaster species group was analyzed by SDS-PAGE in order to investigate protein variations and genetic relationships among the eight species in the three developmental stages of larva, pupa and adult. From the comparison of scanning patterns on the electrophoretic phase by densitometer, three developmental stages showed qualitative and quantitative differences in respective species. In the comparison between species, genetic similarity among the eight species for three stages was calculated by band counting method(Ferguson, 1980). Based on the data of genetic similarity, the biochemical dendrograms in the eight species were constructed. In three developmental stages of 3rd instar larva, pupa, adult, the dendrograms showed same patterns. According to the results, the eight species could be devided into two phyletic groups, one comprises the D. melanogaster, D. simulans, D. lutescens and D. suzukii, while the other includes D. auraria, D. biauraria, D. triauraria and D. rufa. SDS-PAGE proved to be useful in systematics at the stages of larva and pupa as well as adult, although the magnitude of genetic differentiation may be different among the three developmental stages.