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양선모,오인경,오재령,허걸,Sun Mo Yang,In Kyung Oh,Jae Ryung Oh,Kuhl Huh 대한안과학회 2006 대한안과학회지 Vol.47 No.7
Purpose: To report a case of cancer-associated retinopathy developed in a patient with small cell lung cancer, which is a kind of paraneoplastic syndrome. Methods: A 78-year-old woman presented complaining of decreased visual acuity and visual field that had developed about 15 days previously. She was diagnosed with small cell lung cancer 1.5 years ago and underwent 3 cycles of chemotherapy. At presentation, the best-corrected visual acuity was hand motion in both eyes and there was no afferent pupillary defect. Slit-lamp biomicroscopic examination revealed no specific abnormality in the anterior segment of either eye, and intraocular pressure was normal. Posterior segment examination demonstrated remarkable arteriolar narrowing in both eyes, but there was little doubt about the presence of an optic nerve lesion such as optic disc edema or pallor. Results: Fluorescein angiography and brain magnetic resonance imaging (MRI) revealed no significant abnormalities. However, electroretinograms (ERG) demonstrated marked reduction in the a and b waves. Visual evoked response was delayed for the latency period. She was treated with systemic steroid, after which her visual acuity gradually improved.
망막분지정맥폐쇄에서 황반중심부의 후유리체박리가 황반부종에 미치는 영향
김성우,오인경,오재령,허걸,Seong Woo Kim,In Kyung Oh,Jae Ryung Oh,Kuhl Huh 대한안과학회 2006 대한안과학회지 Vol.47 No.3
Purpose: To quantitatively compare the role of posterior vitreous detachment in macular edema associated with branch retinal vein occlusion (BRVO) using OCT. Methods: A retrospective study of 36 eyes with BRVO-associated macular edema was carried out from November 2003 to February 2005. There was posterior vitreous detachment (PVD) in 23 eyes [PVD (+) group], and vitreoretinal attachment on the fovea in 31 eyes [PVD (-) group]. PVD was detected with an indirect ophthalmoscope or 90D lens. The foveal thicknesses of the two groups were measured and compared. Results: The mean foveal thicknesses of the PVD (-) and PVD (+) groups were 398.0±217.2 ?m and 233.6±80.6 ?m, respectively (p=0.000, Mann-Whitney test). The mean BCVA (log MAR) was 0.77±0.52 in the PVD (-) group and 0.40±0.37 in the PVD (+) group (p=0.002, Mann-Whitney test). Conclusions: The extent of macular edema associated with BRVO was significantly less in the PVD(+) group and BCVA was significantly better in the PVD (+) group as well.
유리체절제술과 백내장 동시수술 후 홍채후유착과 연관된 요인들
김성우,김현승,오재령,허걸,Seong-Woo Kim,Hyeon-Seung Kim,Jae-Ryung Oh,Kuhl Huh 대한안과학회 2005 대한안과학회지 Vol.46 No.7
Purpose: Performing simultaneous vitrectomy and cataract procedure has become a widely accepted treatment for cataract patients with vitreoretinal diseases. We evaluated the risk factors of posterior synechia of the iris after such a combined surgery. Methods: We selected the 149 eyes of 149 patients and reviewed the relationship between posterior synechia of the iris and preoperative condition of patients, intraoperative procedures, and postoperative findings. Results: Twenty-six eyes (17.4%) developed posterior synechia; the risk ratio for female patients was 3.382 (95% CI: 1.014-11.277); in patients with uveitis history it was 9.987 (95% CI: 2.329-42.821); in patients with postoperative anterior chamber hyphema it was 17.477 (95% CI: 1.828-167.144); in patients with postoperative anterior chamber fibrin deposition it was 23.52 (95% CI: 2.938-188.299). In cases with silicone-oil tamponade the risk ratio was 8.531 (95% CI: 2.287-31.831) times higher; and in cases with C3F6 gas tamponade it was 15.786 (95% CI: 3.456-72.101) times higher than those with balanced salt solution tamponade. Conclusions: Risk factors of posterior synechia of the iris after a combined vitrectomy and cataract procedure were being female, uveitis history, silicone-oil tamponade, C3F6 gas tamponade, postoperative anterior chamber hyphema, and postoperative anterior chamber fibrin deposition.
증식당뇨망막병증 환자에서 유리체절제술시 일상적인 내경계막제거술의 효과
최영재,김성우,오인경,오재령,허걸.Young Jae Choi. M.D.. Sung Woo Kim. M.D.. In Kyoung Oh. M.D.. Jaeryung Oh. M.D.. Kuhl Huh. M.D.. Ph.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.4
Purpose: To evaluate the efficacy of internal limiting membrane (ILM) removal during vitrectomy in proliferative diabetic retinopathy (PDR) patients. Methods: Seventy-four eyes of 74 PDR patients who underwent vitrectomy were enrolled. All patients had been followed for at least one year. Thirty-three patients who underwent vitrectomy without ILM peeling from January 2004 to February 2005 were assigned to Group A and 41 patients who underwent vitrectomy with ILM peeling from March 2005 to October 2005 were assigned to Group B. Visual acuity (LogMAR), central macular thickness measured by optical coherent tomography (OCT), and presence or absence of macular edema were compared between the two groups at six months and one year after surgery. Results: Postoperative mean best corrective visual acuity (BCVA; LogMAR) were improved significantly in both groups at six months and one year after surgery. However, the overall amount of improvement in vision was not different between the two groups. The mean central forveal thickness in Group B was significantly thinner than in Group A at six months and one year after surgery. There was no difference between the two groups in macular edema incidence at that time. There were no serious complications in Group B by one year after surgery. Conclusions: There was no difference in visual acuity between the Group A and Group B However, the central forveal thickness measured by OCT was thinner in the ILM peeling group, and there were no serious complications in ILM peeling group. Routine ILM peeling during vitrectomy in PDR will help to maintain the structural stability of the macula postoperatively.
잠복 맥락막신생혈관을 동반한 나이관련황반변성에서 베바시주맙 단독치료와 광역학요법 병합치료
오종현,김성우,오재령,권순선,허걸,Jong-Hyun Oh,Seong-Woo Kim,Jaeryung Oh,Soon-Sun Kwon,Kuhl Huh 대한안과학회 2013 대한안과학회지 Vol.54 No.10
Purpose: To compare clinical outcomes between intravitreal bevacizumab (IVB) monotherapy and combined therapy with half-fluence rate verteporfin photodynamic therapy (PDT) for occult choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Methods: Medical records were reviewed in consecutive patients who underwent IVB monotherapy or combined therapy with PDT for occult CNV secondary to AMD and had a 12-month follow-up period. After 3 consecutive monthly IVB injections, both groups were eligible for additional IVB injections when necessary. Best-corrected visual acuity (BCVA), central macular thickness (CMT), and number of additional IVB injections were compared between the groups. Results: Thirty-nine eyes underwent IVB monotherapy (IVB group) and 25 eyes underwent combined therapy (PDT+IVB group). Mean BCVA improved significantly in the PDT+IVB group (p = 0.046) and not in IVB group (p = 0.213). A significant reduction in mean CMT occurred in both groups (p < 0.001). The mean number of additional IVB injections was 1.6 ± 1.33 in the IVB group and 0.5 ± 1.01 in the PDT+IVB group (p = 0.001). There were no serious complications. Conclusions: Combined therapy with half-fluence rate PDT improved BCVA and reduced the number of additional IVB injections in the eyes with occult CNV secondary to AMD.