http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 한영신 ( Young Sin Han ) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
단일항원 감작군과 다항원 감작군의 임상 양상 및 알레르기 지표의 차이: 단일 기관 연구
이종호 ( Jong Ho Lee ),김지현 ( Ji Hyun Kim ),윤신원 ( Sin Weon Yun ),한영신 ( Young Shin Han ),안강모 ( Kang Mo Ahn ),채수안 ( Soo Ahn Chae ),임인석 ( In Seok Lim ),최응상 ( Eung Sang Choi ),유병훈 ( Byung Hoon Yoo ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2011 소아알레르기 및 호흡기학회지 Vol.21 No.4
Purpose: The objective of this study was to identify differences in the clinical manifestations and allergic indices between monosensitized and polysensitized children. Methods: We reviewed retrospective data from the medical records of patients who had chronic or recurrent respiratory symptoms and visited the pediatric clinic at Chung-Ang University Hospital for an evaluation of allergic diseases from January 2003 to January 2011. The patients were categorized into nonsensitized (n=111), monosensitized (n=149), and polysensitized (n=205) groups according to skin prick tests (as classified by five allergen groups). We compared gender, age, family history, admission history, food sensitization, total immunoglobulin E (IgE), peripheral eosinophil counts, eosinophil cationic protein (ECP) levels, forced expiratory volume in 1 second (FEV1), and methacholine provocation tests among the three groups. Results: The frequency of food sensitivity was highest in the polysensitized group (n=101, 49.3%), followed by the monosensitized (n=8, 5.4%) and nonsensitized groups (n=0) (P<0.001). The FEV1 was significantly lower in the polysensitized group than that in the monosensitized and nonsensitized groups (79.4 ± 20.2% vs. 87.2 ±16.0% vs. 87.6 ± 17.1%, respectively) (P=0.013). The total IgE and ECP levels were significantly higher in the polysensitized patients than those in the other patients (P<0.001 and <0.001, respectively). Differences in gender, age, peripheral eosinophil count, and bronchial hyper-responsiveness were not identified between the monosensitized and polysensitized groups. Conclusion: The polysensitized group showed more frequent food hypersensitivity, lower FEV1 values, and higher allergic indices such as total IgE and ECP, suggesting a different atopic phenotype compared with those in the monosensitized group. (Pediatr Allergy Respir Dis(Korea) 2011;21: 277-284)
-
안연화 ( Yeon Hwa Ahn ),여중석 ( Joong Suk Yeo ),이진영 ( Jin Young Lee ),한영신 ( Young Sin Han ),안강모 ( Kang Mo Ahn ),이상일 ( Sang Il Lee ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2009 소아알레르기 및 호흡기학회지 Vol.19 No.3
목적: 땅콩 알레르기는 치명적인 아나필락시스를 일으킬 수 있는 식품 알레르기로, 조리법에 따라서 땅콩단백의 알레르기 항원성이 달라질 수 있다. 본 연구는 다양한 조리법에 따른 땅콩의 구성단백의 변화를 분석해 보고자 하였다. 방법: 생땅콩과 가공처리한 7가지 종류(삶은 땅콩, 10분, 20분, 30분 구운 땅콩, 튀긴 땅콩, 식초에 절인 땅콩, 땅콩버터)의 땅콩을 분쇄한 후, PBS 처리하여 단백을 추출하였고, SDS-PAGE를 시행하여 단백분획을 확인하였다. 그리고, 아토피피부염 환아 중 혈청내 땅콩에 대한 특이 IgE가 15 kU/L이상을 보인 환아 8명의 pooled serum으로 8종류의 땅콩 단백과 IgE immunoblot을 시행하였다. 결과: SDS-PAGE상 구운 땅콩에서는 열처리 시간에 관계없이 Ara h 2에 해당하는 진한 단백띠를 보였고, 튀긴 땅콩과 식초절임에서는 Ara h 1에 해당하는 단백띠가 사라졌다. 조리법에 관계없이 Ara h 3에 해당하는 단백띠가 일정함을 보였으며, 특히 식초절임의 37-40 kDa에서 강한 단백띠를 보였다. IgE immunoblot상 10분 구운 땅콩에서는 Ara h 2 해당 단백띠와 IgE 반응성을 보였고, 튀긴 땅콩과 식초절임에서 Ara h 1 해당 단백띠와의 반응성은 보이지 않았다. 식초절임에서는 전반적인 IgE 반응성은 보이지 않았다. 결론: 저자들은 구운 땅콩에서는 Ara h 1보다는 Ara h 2에 해당하는 단백띠의 항원성이 증가하였고, 튀긴 땅콩과 식초절임에서는 땅콩단백의 항원성이 감소함을 확인할 수 있었다. Purpose: Peanut allergy is a major cause of fatal food-induced anaphylaxis. Cooking methods can affect the allergic properties of peanut proteins. The aim of this study was to determine the allergenicity of peanut according to cooking methods. Methods: Eight kinds of peanut were included in the study: raw peanut, boiled peanut, roasted peanut (10 min, 20 min and 30 min), peanut butter, fried peanut and vinegarish peanut. The proteins were extracted with PBS and analyzed using the SDS-PAGE IgE immunoblot assay with pooled sera from 8 patients with atopic dermatitis. These patients had peanut-specific IgE levels greater than 15 kU/L, which were measured by the CAP-FEIA. Results: The SDS-PAGE IgE immunoblot assay revealed more intense protein bands of Ara h 2 in roasted peanut and peanut butter than in raw, boiled, fried and vinegarish peanut. The protein band of Ara h 1 was not undetected in fried and vinegarish peanut. Ara h 3 had a stable band pattern in all samples, but there was the most prominent band at 37-40 kDa in vinegarish peanut. The IgE immunoblot assay revealed that 10 min roasted peanut had more IgE binding to Ara h 2, and there was no IgE binding to Ara h 1 in fried and vinegarish peanut. In vinegarish peanut, there was almost no IgE binding to it. Conclusion: The results of this study suggest that the roasted peanut may increase the allergenicity of Ara h 2 as compared to Ara h 1. Fried and vinegarish peanut may reduce the allergenicity of peanut. [Pediatr Allergy Respir Dis(Korea) 2009;19:233-240]
-
Thiopental sodium 과 Propofol 의 마취유도효과 및 기관내삽관에 따른 혈역학 변동 비교
박찬진,윤명하,한영신 대한마취과학회 1995 Korean Journal of Anesthesiology Vol.28 No.5
The purpose of this study is to compare thiopental sodium and propofol as to the effects of anesthesia induction and hemodynamic changes associated with endotracheal intubation. Forty healthy adult patients, scheduled for elective surgery under general anesthesia, were randomly assigned to receive either thiopental sodium 5 mg/kg (Group 1, n =20) or propofol 2 mg/kg (Group 2, n=20) as an induction agent. Endotracheal intubation was performed following injection of succinylcholine 1 mg/kg. Anesthesia was maintained with 1.5~2% ethrane and 50% N₂O in O₂. The results were as follows; 1) Both thiopental sodium and propofol revealed high incidence of pain in the site of injection (13/20, 10/20, respectively). 2) The time from the start of injection to spontaneous closing of eyes and to loss of eyelid reflex were 42 and 43 sec in group 1 and 46 and 51 sec in group 2, respectively. 3) The loss of respiratory efforts. Occured in all cases and took 65 and 59 sec, in group 1 and 2 respectively. 4) The blood pressure was more decreased in group 2 than group 1 during induction period, but there was no significant difference between two groups. Also, there was no significant difference of the heart rate between two groups. 5) The increments of systolic blood pressure and rate-pressure-product to endotrachal intubation in group 2 were less than group 1 at time of immediate and 1 minute after intubation. Also, the increments of mean arterial pressure, disastolic blood presure and heart rate were lessen in group 2 than group 1. The retum of blood pressure, heart rate and RPP to the control was fasten in group 2 than group l. In conclusion, propofol may be an alternative to thiopental sodium in patients who require endotracheal intubation without hemodynamic instability.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
