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한명자,경난호 梨花女子大學校 醫科大學 醫科學硏究所 1978 EMJ (Ewha medical journal) Vol.1 No.4
The authors were conducted the studies based on the analysis of the clinical and laboratory features of 145 cases of acute pancreatitis, admitted to the department of internal medicine, Ewha Womans University Hoispital, during the period from January, 1970 to December, 1976. The results obtained are as follows: 1) The incidence of acute pancreatitis was higher in woman than man and its peak level was 20 years and in next, 30 years both male and female. 2) The main symptoms were severe epigastric pain(97.9%) and in next, nausea and vomiting, radiating abdominal pain, fever, indigestion, diarrhea & constipation. The physical examination most frequently showed abdominal tenderness(92.4%) and in next, abdominal distension, muscle rigidity, jaundice & hepatomegaly. 3) The elevation of serum amylase above 300 somogyi unit was 71.7%, that of serum lipase was 45.6%, that of serum bilirubin was 42.4%. CAm/Ccr ratio was increased by more than 1.5~2 times of normal group in acute pancreatitis. 4) In radiologic studies, localized gas distension on small bowel in 93 cases of plain abdomen was 56.0%. Widened C-loop was 24.1% and spasticity of duodenal bulb was 13.8% in 29cases of upper G-1 series and non-visualization of gall bladder was 25.0% in 20 cases of oral GB series. 5) The possible etioloigic factors were overeating, undetermined, alcohol drinking & biliary tract disease in frequent orders. And associated diseases were biliary tract disorder, peptic ulcer & gastritis, pulmonary tuberculosis and paralytic ileus. 6) In 8 cases among 145 cases, surgical operation was performed, as a result of biopsy, hemorrhagic pancreatitis was 4 cases, pancreatic pseudocyst was 2 cases, fat necrosis was 1 case and pancreatic abscess was 1 case. 7) On the therapeutic results, recovery & improvement was 95.1%. No improvement & death were 4.9% each other and relapse was 2.8%.
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한명자,이우형,박이갑 梨花女子大學校 醫科大學 醫科學硏究所 1980 EMJ (Ewha medical journal) Vol.3 No.2
Tuberculous lesions in the liver are a common finding at autopsy in patients with pulmonary tuberculosis. However upto 1956, only 33 cases of tuberculosis the liver have been reported by exploratory lapartory or autopsy in all the world, but recently diagnosis is more easy with development of liver yet. Recently we had the opportunity to observe 31-year-old male patient who had pulmonary tuberculosis and developed clinical course of F.U.O. In this paper we report a case of tuberculous hepatitis which confirmed by liver biopsy and briefly review the literatures.
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數種 마우스와 試藥이 間接 Jerne plaque assay에 미치는 影響
崔東翊,韓明子,李健秀 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.28 No.1
우리나라에서 細胞性免疫實驗을 施行하는데 있어 信憑性 있는 近交系마우스와 細胞에 毒이 없는 試藥을 求하기는 대단히 힘들다. 더욱 各種 試藥의 適否는 間接 Jerne plaque assay의 成功에 決定的 影響을 미쳐왔다. assay에는 肺吸蟲의 代謝産物로 感作한 脾臟細胞를 使用하였다. 우리나라에서 구할 수 있는 各種試藥과 마우스가 plaque assay의 結果에 미치는 影響을 究明하기 위해 3種類의 agar 즉, bacto-agar, refine-agar 및 agarose type Ⅱ, 3種類의 粉末培地, M-199, RPMI-1640 및 Eagle's MEM과 4種類의 近交系 마우스, 즉 ICR, BALB/c, GPC 및 DDY를 求하여 使用하였다. agar와 各種 培地의 溶媒로서는 敎室에서 만든 第1次, 第2次, 第3次蒸溜水와 Gibco硏究所의 3次蒸溜水를 使用하였다. 3種의 agar 中 bacto-agar를 除外한 refine-agar와 agarose type Ⅱ는 slide위의 半凝固 agar가 萎縮되어 實驗에 使用할 수 없었다. Gibco硏究所의 3次蒸溜水와 敎室에서 만든 3次蒸溜水를 使用하였을 때는 마우스脾臟에서 plaque形成細胞를 檢出할 수 있었으나 Gibco硏究所의 蒸溜水가 가장 좋은 結果를 나타내었다. 3種의 培地, M-199, RPMI-1640 및 Eagle's MEM을 使用하였을 때 脾臟當 plaque 形成細胞數는 거의 비슷하여 有意的 差가 없으나 BALB/c마우스에서 가장 좋은 結果를 나타냄을 알았다. It is very difficult to obtain the highly inbred mice and non-toxic reagents to cells in performing immunologic tests in Korea. In addition, the fitness of various reagents has been effected definitely on the success of indirect Jerne plaque assay. The spleen cells sensitized with the metabolite of Paragonimus westermani were used for the assay. In order to determine the effect of reagents and mice on the results of assay, three kinds of agar, bacto-agar, refine-agar and agarose type Ⅱ, three kinds of media, Medium-199, FPMI-1640 and Eagle's MEM and four kinds of mice, ICR, BALB/c, GPC and DDY were employed. The single, double, and triple distilled water of our laboratory and the triple distilled water of Gibco laboratory were used to dissolve the agars and media. Among the 3 kinds of agars examined, the semi-solid layers of refine-agar and agarose type Ⅱ on the slides were markedly shrunken, so that these agars could not used for the assay, but no shrinkage was observed by bacto-agar. When the triple distilled water of our and Gibco laboratories were used, the plaque forming cells were found from the spleen of sensitized mice, and the best results were encountered by use of Gibco laboratory. When the 3 kinds of media, M-199, RPMI-1640 and Eagle's MEM were used in performing the assay, there were minimal or no changes in the detection of plaque forming cells, and among the 4 kinds of inbred mice, the best results were obseved from the BALB/c mice.
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一部 農村地域社會에 對한 社會醫學的 調査硏究 : 京畿道 楊州郡 和道 瓦阜地域 Hwa-do and Wa-Boo Area, Yangju Gun
金奏孜,安淑,尹錫琬,趙義淑,韓明子 이화여자대학교 의과대학 1974 梨花醫學誌 Vol.- No.6
A study on population and socio-medical status was carried out in the Korean rural communities, Hwa-do and Wa-boo area from July 20 to July 27, 1973. This study was directed by the department of preventive medicine, Ewha medical college as a part of the student training program for community health. The survey team composed of two staff and nine medical students visited to the 205 households in the area. The results were obtained as follows; 1. Total population in the study area was 1248 composed of 667males (53.5%) and 581 female (46.5%). 2. Education level of househead was prominent in primary school with 47.8% and in secondary school with 20.5%. 3. Among the occupation of house head, farmer was prominent in Hwa-do area with 75.7% and labourer in Wa-boo with 34.1%. 4. Average monthly living allowance of the 205 families in the study area was 15,000±10,000(￦). 5. Average size of family in number was 6.1 person. 6. Utility rate of radio in families was 89 percent and that of news-paper was 25 percent. 7. Current users of contraception among the fecund women was 29.2 percent. 8. Morbidity rate for all causes was 198 per 1,000 inhabitants and that of male and female was 164 and 208 respectively. 9. The order of the five maajor diseases according to the morbidity rate (per 1,000) was as follows; 1) Symptoms and Illdefined Condition (65) 2) Diseases of the Digestive System (48) 3) Disease of the Respiratory System (18) 4) Infectious and parasite disease (18) 5) Disease of Hervous System and Sense Organs (16) 10) Current utility rate of doctor's clinic and drug store was 38.2 percent and 37.2 percent respectively.
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