쑥 추출액을 이용한 Microcystis aeruginosa 제거 및 성장억제 연구

최희정,Choi, Hee-Jeong 한국물환경학회 2017 한국물환경학회지 Vol.33 No.4

Microcystis aeruginosa (M. aeruginosa) is a cyanobacterium species that can form harmful algal blooms in freshwater bodies worldwide. The use of Artemisia asiatica extracts to control M. aeruginosa inhibition will be environmentally friendly and promising. Artemisia asiatica extracts removed successfully upto 88% of M. aeruginosa pH 8 at $25^{\circ}C$ of temperature. These results was indicated that the amount of 2.24 g/L Artemisia asiatica extracts was removed 1g dryweight/L of M. aeruginosa. The kinetic data showed substrate inhibition kinetics and maximum growth rate was obtained when the M. aeruginosa was grown in medium containing 2.5 g/L of initial concentration of Artemisia asiatica extracts. In the various growth control models, Luong model showed the highest correlation coefficient of 0.9916. Therefore, the Luong model was the most suitable control model for the growth control of M. aruginosa using Artemisia asiatica extracts. In conclusion, the growth control of M. aruginosa using Artemisia asiatica extracts can be applied in the field without controlling the temperature and pH of rivers and streams, and it is possible to control the growth of M. aruginosa efficiently in a short time. The natural extract, Artemisia asiatica extracts, can be a promising inhibition due to its high efficiency and low dose requirements.

경남 남해지역 장수노인의 영양섭취량에 영향을 미치는 요인

최희정 ( Hee Jeong Choi ),김경업 ( Gyeong Eup Kim ),정효숙 ( Hyo Sook Cheong ),정숙자 ( Suk Ja Jung ),김성희 ( Sung Hee Kim ) 대한영양사협회 2005 대한영양사협회 학술지 Vol.11 No.1

경남 남해지역 장수노인의 식습관 및 건강관련 요인에 관한 연구

최희정(Hee-Jeong Choi),김성희(Sung-Hee Kim) 한국식품영양과학회 2003 한국식품영양과학회지 Vol.32 No.7

본 연구는 경남 남해군 서면과 설천면에 거주하는 85세 이상의 고령 노인 중에서 거동에 불편함이 없고 특별한 질환이 없는 대체로 건강한 노인 100명을 대상으로 하였다. 대상자들의 일반적인 특성, 식습관 및 건강관련요인들을 조사한 결과는 다음과 같다. 교육수준은 무학이 95.0%로서 남자는 83.3%, 여자는 98.7%를 나타내었고 가족형태는 아들과 함께사는 경우가 63.0%로 가장 많았으며 딸과 함께 사는 경우가 1.3%로 가장 적었다. 월 평균 용돈은 5만원 이하가 51.7%로 가장 많았고 81.0%의 노인들이 자녀에게 용돈을 받는 것으로 나타났다. 부모님의 사망연령은 아버지가 평균 67.3±15.9세, 어머니가 평균 68.1±16.6세로 거의 유사하였으나 남자 노인인 경우는 아버지가 여자노인인 경우는 어머니가 더 오래 생존했던 것으로 나타났다. 하루에 세 끼니를 섭취하는 노인이 평균 84.0%로 가장 많았는데 여자(89.5%)가 남자(66.7%)에 비해 유의적으로 많았으며(p<0.05) 남녀 각각 91.7%, 93.4%의 노인이 규칙적인 식습관을 갖고 있었다. 조사 노인의 약 77.1%가 금기식품이 없다고 하였고 약 90.5%가 건강 식품이나 보충제를 섭취하지 않고 있었다. 음주는 남자 58.3%, 여자 35.5%가 하는 것으로 나타났고 음주시작 연령은 남자는 30세 이전이 71.4%로 가장 많았으며 여자는 31~40세가 33.3%로 가장 많았고 일일 평균 알코올 섭취량은 남자는 11~30 g, 여자는 10 g이하가 대부분이었다. 남자 33.3%, 여자 28.9%가 흡연을 하였으며 흡연시작 연령은 남자는 20세 이전, 여자는 31~40세가 가장 많았고 흡연량에 있어서는 하루 5개비 이하가 남녀 각각 37.5%, 50.0%로 가장 높은 비율을 차지하였다. 조사 노인들의 평균 수면시간은 6~8시간, 활동시간은 4~5시간이 가장 많았고 남자 91.7% 여자 85.5%가‘건강하다’, 남자 58.3% 여자 67.1%가 ‘행복하다’라고 스스로 인식하고 있었다. The purpose of this study was to investigate dietary habits and health-related behaviors in elderly people aged over 85 years residing in Namhae-gun Kyungnam. The subject group of this study was composed of 24 males and 76 females, the average age being 88.9±4.0 years old. The mean age of their parents' death were 67.3±15.9 years for the father and 68.1±16.6 years for the mother. Most of the subjects had a regular meal pattern consuming three meals a day, and the female (89.5%) had more regular meals than the male (66.7%). Most of the subjects showed to have no taboo foods (77.1%) and health foods or supplements (90.5%). The rates of alcohol drinking and smoking showed to be 46.8% and 31.1%, respectively, and the quantities of them were a little. Of the subjects, 65.6% spend 6~8 hours for sleeping and 57.6% spend 4~5 hours for activity. Most of the subjects recognized to be healthy (88.7%) and happy (62.7%).

점토광물을 이용한 염료제거

최희정 ( Hee-jeong Choi ) 한국물환경학회(구 한국수질보전학회) 2016 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2016 No.-

해양 미세조류를 이용한 김치공장폐수의 영양염류 제거

최희정 ( Hee Jeong Choi ) 한국수처리학회 2014 한국수처리학회지 Vol.22 No.3

The aim of this study was to investigate the nutrient removal and biomass productivity in the Kimchi wastewater using microalgae. The experiment operated for 6 days in the OPPBR (Optical Panel Photobioreactor), and using marin microalgae as Nannochloris sp. The obtained result indicated that the biomass productivity of 1.207 g/L from 0.367 g/L initial concentration in 6 days was reached with light transmittance of 92% at a 305 mm depth in the OPPBR. The total consumption rates of BOD (Biochemical Oxygen Demand) and COD (Chemical Oxygen Demand) in the OPPBR were found to be 98.06% and 87.34%, respectively. Additionally, the removal rates of TN, NO3-N, TP and PO4-P were 86.21%, 77.81%, 94.87% and 93.00% in Kimchi wastewater using Nannochloris sp., respectively. These results indicated that the OPPBR process with Nannochloris sp. was highly effective for COD, BOD and nutrient removal compared to the conventional biological process in the kimchi wastewater. Therefore, the OPPBR process with Nannochloris sp. was effective for nutrient removal and biomass productivity and can be applied to treat kimchi wastewater in treatment plant.

폐경 후 골다공증의 새로운 치료제 스트론튬 라넬레이트

최희정 ( Hee Jeong Choi ) 대한폐경학회 2009 대한폐경학회지 Vol.15 No.1

Strontium ranelate is a novel drug for osteoporosis that has a duel effect on bone remodeling. Some mechanisms that underlie the beneficial effects of strontium ranelate on bone metabolism and strength have now been identified. Strontium ranelate induces pre-osteoblast replication, osteoblast differentiation, collagen type I synthesis, and bone matrix mineralization, probably through a calcium-sensing receptor- dependent mechanism. It also inhibits the differentiation and activity of osteoclasts by increasing the OPG/RANKL ratio. Preclinical studies have shown that this dual effect increases bone mass and improves bone microarchitecture and strength in intact rodents, as well as prevents bone loss in animals with osteopenia. Thus, strontium ranelate rebalances bone turnover in favor of enhanced bone strength. Treatment efficacy with strontium ranelate has been assessed in postmenopausal women in two large, double-blind, placebo- controlled clinical trials. During these clinical trials, strontium ranelate increased bone mineral density by 14.4% in the lumbar spine and by 8.2∼8.3% in the femoral neck at 36 months, compared with placebo. During the same period, strontium ranelate decreased the risk of vertebral fractures and non-vertebral fractures by 41% and 16%, respectively. Moreover, it showed efficacy in the different subgroups of patients with postmenopausal osteoporosis. In the context of clinical trials, nausea and diarrhea were the most common adverse events occurring within the first three months. Nevertheless, there were no significant differences between the groups with respect to the incidence of serious adverse events.

폐경 여성에서 인슐린저항성의 예측인자

최희정 ( Hee Jeong Choi ),윤경은 ( Kyung Eun Yun ) 대한폐경학회 2010 대한폐경학회지 Vol.16 No.2

연구목적: 이 연구는 폐경 후 여성에서 비만, 높은 alanine aminotransferase (ALT)와 인슐린저항성 간에 연관성을 알아보고, 대사증후군과 비교하여 이들 두 요인이 인슐린저항성을 예측하는 정도를 비교하기 위해 시행하였다. 연구재료 및 방법: 이 연구는 건강증진센터를 방문한 606명의 폐경 후 여성을 대상으로 하였다. 설문지와 문진을 통해 병력과 생활습관에 대해 조사하였고 신체계측과 혈압을 측정하였다. 검사실 검사로는 공복 혈당과 인슐린, 간 기능검사, 지질 검사 등을 하였고, 혈당과 인슐린 농도를 이용하여 호마지수를 계산하였다. 대사증후군은 NCEP-ATP III의 정의에 따라 분류하였다. 호마지수를 사분위수로 나누어 최고 사분위수에 해당하는 군을 인슐린저항성이 있는 군으로 정의하여 각 요인의 인슐린저항성에 대한 교차비를 구하였다. 결과: 비만과 높은 ALT의 빈도는 호마지수가 높을수록 의미 있게 증가하였다. 연령, 흡연, 운동을 보정하고 비만과 높은 ALT는 각각 인슐린저항성의 위험을 의미 있게 증가시켰으며, 비만과 높은 ALT을 모두 가지는 여성 (OR=5.87; 95% CI 2.93∼11.74)은 대사증후군이 있는 여성 (OR=3.43; 95% CI 2.18∼5.41)에 비해 인슐린저항성의 위험이 더 높은 것으로 나타났다. 결론: 폐경 후 여성에서 비만과 높은 ALT는 인슐린저항성과 연관이 있으며, 이 두 요인이 모두 있는 경우 대사증후 군보다 인슐린저항성을 더 잘 예측할 수 있는 것으로 나타났다. Objectives: Insulin resistance plays an important role in cardiovascular diseases, type 2 diabetes, and non-alcoholic fatty liver disease. The objective of this study was to determine the association between obesity and elevated alanine aminotransferase (ALT) with insulin resistance and compare these factors with metabolic syndrome in postmenopausal women. Methods: We analyzed 606 postmenopausal women who had visited the Health Promotion Center. The medical history and lifestyle data were collected by questionnaire and history taking. Anthropometric parameters and blood pressure were measured. Laboratory tests included fasting glucose and insulin levels, and liver and lipid profiles. Metabolic syndrome was defined based on NCEP-ATP III criteria. As a maker of insulin resistance, the homeostatic model assessment-insulin resistance (HOMA-IR) was calculated. We grouped all subjects into four groups, based on the quartiles of HOMA-IR. The top fourth quartile group was defined as the group with insulin resistance. We performed multivariate logistic regression analysis for the odds ratio of the risk for insulin resistance. Results: The prevalence rates of obesity (body mass index ≥ 25 kg/㎡) and elevated ALT (≥ 34 U/L) increased with increased HOMA-IR. Obesity and elevated ALT were associated with insulin resistance, after adjusting for age, smoking status, and exercise. Women with co-existing obesity and elevated ALT were at increased risk for insulin resistance (OR=5.87; 95% CI, 2.93∼11.74) compared to women with metabolic syndrome (OR=3.43; 95% CI, 2.18∼5.41). Conclusion: Obesity and elevated ALT are associated with insulin resistance in postmenopausal women. A combination of these factors is superior to metabolic syndrome in predicting insulin resistance.

카페인을 이용한 유해 녹조류 생장제어

최희정 ( Hee-jeong Choi ) 한국수처리학회 2016 한국수처리학회지 Vol.24 No.5

Microcystis aeruginosa is a cyanobacterium species that can form harmful algal blooms in freshwater bodies worldwide. The use of caffeine to control nuisance algae by allelopathic inhibition will be environmentally friendly and promising. Caffeine removed successfully upto 82% of Microcystis aeruginosa at the following optimal conditions: pH 8, upto 25 °C of temperature, 100 rpm of mixing rate, 30 min of mixing time. These results was indicated that the amount of 2 g/L caffeine was removed 1g dryweight/L of Microcystis aeruginosa. The kinetic data showed substrate inhibition kinetics and maximum growth rate was obtained when the Microcystis aeruginosa was grown in medium containing 0.7 g/L of initial concentration of caffeine. Different substrate inhibition models were fitted to the kinetic data and found the Luong model was best. The model predicted kinetic parameters were in agreement with the experimental findings. The caffeine can be a promising inhibition due to its high efficiency and low dose requirements.

온도, 광세기 및 pH에 따른 Chlorella Vulgaris 증식률

최희정(Hee Jeong Choi),이승목(Seung Mok Lee) 大韓環境工學會 2011 대한환경공학회지 Vol.33 No.7

본 연구는 온도, 광세기 및 pH가 Chlorella vulgaris (C. vulgaris)의 증식률에 미치는 영향을 알아보고자 하였다. 각 조건에서의 효율을 평가하기 위하여 C. vulgaris (FC-16) (3~8 μm)를 Jaworski`s Medium에 증식시킨 뒤, 다양한 온도(10℃, 15℃, 20℃, 25℃, 30℃, 35℃)와 다양한 광세기(100~800 μEm-2s-1) 및 다양한 pH (3, 4, 5, 6, 7, 7.5, 9) 조건에서 실험하였다. 실험결과, 25~30℃ 조건에서는 10℃ 조건과 비교 시 같은 양의 C. vulgaris를 증식하는데 걸리는 시간은 약 5.2~5.5배 빨랐고, Chlorophyll a는 5~5.5배 높았으며, 단위 면적당 cell volume은 14% 이상 높아 C. vulgaris 최적 배양온도는 25~30℃로 조사되었다. C. vulgaris 배양기간의 경우, 증식속도가 5일까지는 느리게 증가했지만, 6일 이후부터 15일까지는 폭발적으로 증가했고, 15일 이후에는 거의 증식이 멈춰 15일 이내가 적당한 것을 알 수 있었다. C. vulgaris 증식을 위한 최적 pH는 pH 7~7.5로 조사되었다. The aim of this study was to investigate the efficiency of temperature, light intensity and pH on the growth rate of Chlorella vulgaris (C. vulgaris). The size of C. vulgaris (FC-16) was 3-8 μm, having round in shape. The cells of C. vulgaris (FC-16) was cultured in the Jaworski`s Medium with deionized water. To evaluate the efficiency of temperature, light intensity and pH on the growth rate of C. vulgaris, six different fractions of temperature (10℃, 15℃, 20℃, 25℃, 30℃, 35℃), various light intensities (100-800 μEm-2s-1) and seven different fractions of pH (3, 4, 5, 6, 7, 7.5, 9) were prepared. The growth rate of C. vulgaris cultivation was approximately 5.2 to 5.5 times faster, the concentration of Chlorophyll a was also 5 to 5.5 times higher, and cell volume per unit area was 14% higher at 25℃ to 30℃ than those at 10℃. Therefore, the optimal temperature for cultivation of C. vulgaris was estimated 25℃ to 30℃. The growth rate of C. vulgaris increased slowly up to 5 days, exploded after 5 days until 15 days, and then stoped after that. The optimum cultivation period of C. vulgaris was estimated as 15 days. The optimum pH for the growth rate of C. vulgaris was determined pH 7 to 7.5.

옥수수속대를 이용한 세차장 폐수 흡착 처리

최희정 ( Hee-jeong Choi ) 한국수처리학회 2017 한국수처리학회지 Vol.25 No.3

The aim of this study was to investigate the car wash wastewater using corncob. Corncob was removed successfully the organic and anorgnic matters in the car wash wastewater at the following optimal parameters: 10 g/L of corncob, 150 rpm of mixing rate and from 6 to 7 of pH. The removal efficiency of turbidity, TDS (Total Dissolved Solid), and ABS (AlkylBenzene Sulfonates) were very high, more than 96%. However COD (Chemical Oxygen Demand), TN (Total Nitrogen) and TP (Total Phosphorus) was found to be 63-65%, 83-87% and 83-84%, respectively, and was relatively low removal efficiency compared turbidity, TDS and ABS. In particular, COD and TP exceeded the wastewater discharge standard and it is considered that post-treatment is necessary for stable treatment of car wash wastewater. Despite the low COD removal, treating car wash wastewater using corncob is very attractive. Because corncob can be treated with abandoned agricultural by-products to treat wastewater, and environmentally friendly because they are not using chemicals. Especially, turbidity, TDS and ABS have high removal efficiency, so that it is possible to reduce the processing cost of wastewater treatment if they are used as pre-treatment.