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최흥재 ( Heung Jai Choi ),이해선 ( Hae Sun Lee ),김정숙 ( Chung Soo Kim ) 대한내과학회 1973 대한내과학회지 Vol.16 No.8
The electron microscope has added a new set of dimension to study of the pathology of various kinds of liver diseases. From these observations a new pathology has been emerging, organelle pathology, in which the altered structure as well as the altered fun
최흥재 ( Heung Jai Choi ),임륭의 ( Young Eui Lim ),김창권 ( Chang Kwon Kim ),홍승록 ( Seung Nock Hong ) 대한내과학회 1972 대한내과학회지 Vol.15 No.4
A extremely rare case of gastrobronchial fistula is reported with brief review of literatures. A 68-year-old Korean woman entered the Severance Hospital, Yonsei University College of Medicine, because of sudden onset of chills, high fever and cough with pr
최흥재 ( Heung Jai Choi ),박호길 ( Ho Kil Park ),김춘규 ( Choon Kyu Kim ),최홍열 ( Hong Yul Choi ) 대한내과학회 1971 대한내과학회지 Vol.14 No.6
The tuberculous involvement of the duodenum is rare, although the intestinal tuberculosis elsewhere is not an unual disease. Proof, following operaton or autopsy on a patient who was considered to have benign ulcer, malignancy of pancreas or annular pancre
각종 간질환 환자에서 섬유소용해 활성도 ( Fibrinolytic Activity ) 에 관한 연구
최흥재(Heung Jai Choi),문영명(Young Myoung Moon),정재복(Jae Bock Chung),한광협(Kwang Hyub Han),전재윤(Chae Yoon Chon),박준용(Joon Yong Park),윤홍섭(Hong Sup Yoon) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A To assess the fibrinolytic activity and coagulation defects in various liver diseases, antithrombin III, fibrin degradation products and prothrombin time were measured in the plasma of 49 patients with various liver diseases including liver cirrhosis, hepatoma, acute viral hepatitis and obstructive jaundice. Also antithrombin III was measured in the plasma of 29 normal controls. The results were as follows: 1) The antithrombin III level was significantly lower in liver cirrhosis and hepatoma than in controls. 2) The fibrinogen was significantly higher in obstructive jaundice than in the others. 3) Small amounts of FDP were found in some patients with liver cirrhosis and hepatoma. 4) In the cirrhotic patients, a significant difference in antithrombin III level was found between patients with FDP (+) and those with FDP (-). 5) The prothrombin time was significnatly more prologned in liver cirrhosis than in the others. 6) A significant correlation was found between antithrombin III and prothrombin time (r=0.48). 7) Comparing cirrhotic patients classified as Child A, B and C, the antithrombin III level was lower in Child C and the prothrombin time was more prolonged than in Child A and B. FDP was found in all but one of the patients classified as Child C.
간 , 담도 및 췌장 : 원발성 간암환자 및 만성 HBsAg carrier 의 세포면역기능에 관한 연구
최흥재(Heung Jai Choi),이상인(Sang In Lee),정재복(Jae Bok Chung),신용운(Yong Woon shin),전재윤(Jae Yoon Chon) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
N/A The extremely variable course of disease after infection with hepatitis B virus is usually explained by differences in the host response to the hepatocytes carring viral antigens. Since the hepatitis B virus is not directly cytopathic for infected hepatocytes, host determined immunologic response is considered a likely pathogenetic determinant in this disease. These immunological reactions may be regulated by T lymphocyte subpopulations, especially helper and suppressor cells. The importance of a balance between helper and suppressor cells in maintaining immune homeostasis has recently been illustrated. In order to determine cellular immune function, the peripheral blood lymphocyte count, total T and B lyrnphocyte subsets, and T cell function by phytohemagglutinin (PHA) and concanavalin A (Con A) stimulation were estimated in 30 patients with primary hepatorna, 8 chronic HBsAg carriers and 20 healthy controls in Yonsei University Severence Hospital during the period from March to October 1986. The results were as fol)ows: 1) The peripheral blood lymphocyte count decreased significantly m patients with hepatoma than chronic HBsAg carriers and normal control(p<0.05), but there was no significant difference in patients with hepatoma between HBsAg positive and negative group. Active and total T lymphocytes decreased significantly in patients with hepatoma than normal control (p<0.05), but there was no significant difference in patients with hepatoma between HBsAg positive and negative group. 2) OKT4 and OKT4/OKT8 ratio decreased, and OKT8 increased significantly in patients with hepatoma than normal control(p<0.05), but there was no significant difference in patients with hepatoma between HBsAg positive and negative group. 3) The ratio of stimulation index by Con A decreased in patients with hepatoma but increased in chronic HBsAg carriers. The ratio of suppressor cell removal index to con A increased significanty in patients with hepatoma but not increased significantly in chronic HBsAg carriers. In summary, the status of HBsAg was not important but an immunoregulatory abnormality might contribute to the pathogenesis and natural course of primary hepatoma.
기관지담도누 , 선천성 무담낭증 및 어린선을 동반한 1 예
최흥재 ( Heung Jai Choi ),허갑범 ( Kap Bum Huh ),정진각 ( Chin Kak Chung ),김연중 ( Yun Jung Kim ) 대한내과학회 1969 대한내과학회지 Vol.12 No.5
A case of bronchobiliary fistula associated with congenital absence of gall bladder and ichthiosis is presented. The patient is a 28 years old Korean farmer complaining of severe cough with massive bile stained sputum for 10 months. Jaundice was present fo