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기후변수와 쌀 생산성: 패널 지역자료를 이용한 준모수적 분석
조현경 ( Hyun Kyoung Cho ),조은빛 ( Eun Bit Cho ),권오상 ( Oh Sang Kwon ),노재선 ( Jae Sun Roh ) 한국농업경제학회 2013 農業經濟硏究 Vol.54 No.3
The purpose of this study is to estimate the impacts of climate variables on rice producticity in Korea. In order to allow for a flexible functional relationship, teh penalized spline regression whith is a semi-parametric model is used. A panel data set of 49 cities and towns for the period from 1996 to 2011 is used for estimation. The spline regression model allows random intercepts in-corporating the panel nature of the data set. Moreover, we identify the observations with extreme weather conditions such as flood in order to incorporate the increasing variability of climate factors. The study finds that rice productivity is significantly affected by technical change, sunshine du-ration and temperature in the grain-filling months. It is found that the variables of sunshine dura-tion must be incorporated as non-parametric elements of the semi-parametric model. There is a positive relationship between sunshine duration and productivity. An inverted U-shape relationship between temperature and productivity is found. The study shows that the peak temperature comes earilier if the panel-nature of the data is taken into account.
조현경(Hyun-Kyoung Cho),황은영(Eun-Young Hwang),문정혜(Jeong-Hae Moon),류홍수(Hong-Soo Ryu) 한국식품영양과학회 1999 한국식품영양과학회지 Vol.28 No.2
우리나라의 대표적인 양식 어류인 넙치와 붕어를 전통적인 조리방법(100℃, 5hr)에서 조리한 후 고음과 잔사의 영양성 평가를 통하여 전통적인 수산 가공식품의 대량 생산 및 이용책을 제시함으로 양식 어류의 효율적인 이용방안을 마련하고자 하였다. 넙치와 붕어 생육을 구성하는 주된 아미노산은 glutamic acid, aspartic acid, lysine, leucine 등으로 전체 아미노산의 약 44%를 차지하였다. 고음은 생육에 비해 수용성 아미노산인 proline과 glycine이 2배 이상 높게 정량되었으나, aspartie acid, glutamic acid 및 lysine이 약 20~25% 정도로 감소되었으며, 필수아미노산인 leucine, isoleucine, 및 methionine 등의 함량도 생육에 비해 비교적 낮게 나타났다. 이와는 반대로 잔사의 구성아미노산은 histidine을 제외하고는 생육과 비슷하거나 약간 높은 경향을 보였다. 고음의 유리아미노산 총량은 생육에 비해 2배 정도 높게 나타났으며, 특히 taurine, glutamic acid, proline, lysine, 및 ammonia 등의 함량이 매우 높게 나타났다. 고음의 in vitro digestibility는 생육보다 4~6% 정도 낮게 나타났으나, 잔사는 오히려 생육보다 더 높은 소화율을 나타내었고, trypsin 비소화성 물질(TI)의 양도 생육이나 고음에 비해 60% 정도로 낮게 나타났다. 유효성 lysine 함량은 고음의 경우 열처리에 의해 18(넙치)~24%(붕어) 정도 낮아졌으며, 잔사의 경우도 이와 유사하게 나타났다. Rat를 이용한 in vivo 실험 결과 PER과 NPR은 casein군에 비해 고음 섭취군은 유의적으로 낮게 나타났으며, 잔사 섭취군은 casein 군보다 비슷하거나 더 높게 나타났다. in vivo apparent digestibility는 casein군(92.5%), 잔사군(88~91%), 고음군(87%)의 순서로 in vitro digestibility의 결과와 비슷한 경향으로 나타났다. 28일간 조제한 사료를 섭취시킨 후 혈액을 취하여 생화학적 성분들을 분석해 본 결과 혈청 중의 glucose, total protein, GOT, GPT, alkaline phosphatase, creatinine의 값이 차이를 보이지 않아 고음을 섭취한 군의 체중 감소가 각종 생체조직의 생리적 기능에 아무런 영향을 미치지 않는다는 것을 확인하였다. To confirm the food quality of conventionally processed fish extracts, protein quality of boiled crucian carp(Carassius carassius) and bastard halibut(Paralichthys olivaceus) extracts and their residues were evaluated. For the both fish extracts, some of the essential amino acids were lowered significantly but two times more proline and glycine were detected in extracts than those in raw fish meats. Boiling(100℃, 5 hours) caused 1.8(crucian carp)~2.4(bastard halibut) times more total free amino acid contents in fish extracts as compared to those in original fish meats. Taurine, glutamic acid, proline, lysine, and ammonia were the predominant free amino acids released in fish extracts. In vitro digestibility of boiled fish extracts were lower at a level of 4~6% than those of raw fish meats. Fish extraction residue had a higher in vitro digestibility and had a 60% lower level of TI than that of original fish meats. 18(bastard halibut)~24%(crucian carp) of available lysine was reduced in boiled fish extracts but a remarkable variation was not noted between extracts and residues. PERs and NPRs of fish extracts were significantly lower than those of casein, while those values of extraction residue were slightly higher as compared to those of control(ANRC casein). In vivo apparent digestibility exhibited a similar trend to in vitro digestibility. Hematological properties in serum of rat fed with fish extracts and residue were not changed significantly but the serum cholesterol concentration were reduced in rats fed fish extraction residue comparing with those of control. These results suggest that body weight loss due to fish extracts may not affect physiological changes.
인진(茵蔯), 울김(鬱金), 지실(枳實) 추출물(ACA)이 HepG2 세포에서 나타나는 이상지질혈증 관련 인자 발현 및 항산화에 미치는 영향
유주영,조현경,유호룡,설인찬,김윤식,Ryu, Ju-young,Cho, Hyun-kyoung,Yoo, Ho-ryong,Seol, In-chan,Kim, Yoon-sik 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.3
Objective: To investigate the effect of Artemisiae Iwayomogii Herba, Curcumae Radix, and Aurantii Fructus Immaturus complex extract (ACA) on dyslipidemia-related factor expression and anti-oxidation in HepG2 cells. Method: After treatment with ACA in the HepG2 cells, DPPH, ABTS radical scavenging activity, ROS production, and glutathione (GSH) production were measured. The free fatty acid, lipid peroxidation (MDA), ACAT1, and HMG-CoA reductase mRNA expression were measured in the HepG2 cells after treatment with ACA. Results: 1. DPPH, ABTS radical scavenging activity increased in an ACA concentration-dependent manner. 2. ACA significantly decreased ROS production in comparison to the control group. 3. ACA significantly increased glutathione production. 4. ACA significantly decreased free fatty acid and lipid peroxidation (MDA) in the HepG2 cells. 5. ACA decreased the mRNA expression of ACAT1 and HMG-CoA reductase. Conclusion: These results suggest that Artemisiae Iwayomogii Herba, Curcumae Radix, and Aurantii Fructus Immaturus complex extract (ACA) inhibits dyslipidemia-related factor expression and that it is effective in anti-oxidation. A future in vivo experiment with ACA is needed to investigate the effect on anti-dyslipidemia. It is expected that ACA is effective in anti-dyslipidemia and applied to cardiovascular disease, ischemic heart disease, stroke, etc.
한인진(韓茵蔯), 울금(鬱金), 산사(山査), 단삼(丹蔘) 발효복합추출물이 RAW264.7 및 HUVEC 세포에서 나타나는 이상지질혈증 관련 염증인자 발현 및 항산화에 미치는 영향
이강욱,조현경,유호룡,설인찬,김윤식,Lee, Kang-wook,Cho, Hyun-kyoung,Yoo, Ho-ryong,Seol, In-chan,Kim, Yoon-sik 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4
Objectives: To investigate the effect of fermented extract of Artemisiae Iwayomogii Herba, Curcumae Longae, Crataegi Fructus and Salviae Miltiorrhizae Radix (FMH) on anti-inflammation associated with dyslipidemia and anti-oxidation in RAW264.7 and HUVEC cells. Methods: The total polyphenols, total flavonoids, DPPH radical scavenging activity, ABTS radical scavenging activity, and cytotoxicity of FMH were measured. RAW264.7 cells treated with FMH were tested for production of NO, and for cytokine and LTB4 levels and HUVEC cells treated with FMH were examined for production of cDNA of genes related to inflammation. Results: 1. FMH contained polyphenols and flavonoids. The DPPH and ABTS radical scavenging activity of FMH increased in a concentration-dependent manner. 2. FMH treatment inhibited the production of nitric oxide (NO), cytokines, and LTB4 in RAW264.7 cell when compared to the untreated control group. 3. FMH decreased the transcription of pro-inflammatory genes, whereas it increased transcription of anti-inflammatory genes, in HUVEC cells. Conclusion: FMH is effective as an antioxidant and for treatment and prevention of dyslipidemia, atherosclerosis, ischemic heart disease, stroke, and other cardiocerebrovascular diseases.