http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
$Fe^{2+}$와 $H_2O_2$에 의한 Hyaluronic Acid, Lipid와 Collagen의 산화성 손상에 나타내는 Harmaline과 Harmalol의 영향
조인성,신용규,이정수,Cho, In-Sung,Shin, Yong-Kyoo,Lee, Chung-Soo The Korean Society of Pharmacology 1995 대한약리학잡지 Vol.31 No.3
Harmaline을 포함한 ${\beta}-Carboline$ 알카로이드들은 마이크로조움의 효소성 또는 비효소성 지질 과산화를 억제한다고 제시되고 있으나, 이들의 항산화 작용기전은 분명하지 않다. 본 연구에서는 $Fe^{2+}$와 $H_2O_2$에 의한 hyaluronic acid, 지질과 콜라젠의 산화성 손상에 있어 harmaline과 harmalol의 항산화 능력을 관찰하였다. 또한 반응성 산소대사물에 대한 이들의 제거작용을 조사하였다. Harmaline, harmalol, superoxide dismutase, catalase와 DMSO는 $Fe^{2+}$와 $H_2O_2$에 의한 hyaluronic acid의 변성과 $Fe^{2+}$에 의한 지질 과산화를 억제하였다. 이들 반응에서 DABCO는 hyaluronic acid의 변성을 억제하였으나 지질 과산화에 영향을 나타내지 않았다. ${\beta}-Carboline$은 $Fe^{2+}$, $H_2O_2$와 ascorbic acid에 의한 cartilage collagen의 변성을 억제하였다. Superoxide dismutase에 의하여 억제되는 $Fe^{2+}$의 자가산화에 따른 ferricytochrome c의 환원은 harmaline과 harmalol의 영향을 받지 않았다. 또한 이들은 $H_2O_2$에 대하여 분해작용을 나타내지 않았다. $Fe^{2+}$와 $H_2O_2$의 존재하에서 OH 생성은 harmaline, harmalol과 DMSO에 의하여 억제되었다. Harmaline과 harmalol은 반응성 산소대사물인 OH 과 아마도 철이온-산소 복합체에 대한 제거작용으로써 $Fe^{2+}$와 $H_2O_2$에 의한 hyaluronic acid, 지질과 콜라젠의 산화성 손상을 억제하고, 항산화 능력을 나타낼 것으로 추정된다. ${\beta}-Carboline$ alkaloids including harmaline have been shown to inhibit enzymatically or nonenzymatically induced-lipid peroxidation of microsomes. This study was done to explore the antioxidant ability of harmaline and harmalol on the oxidative injuries of hyaluronic acid, lipid and collagen by $Fe^{2+}$ and $H_2O_2$. Their scavenging actions on reactive oxygen species were also examined. Harmaline, harmalol, superoxide dismutase, catalase and DMSO inhibited both degradation of hyaluronic acid by $Fe^{2+}$ and $H_2O_2$ and lipid peroxidation of microsomes by $Fe^{2+}$. In these reactions, DABCO inhibited degradation of hyaluronic acid but did not affect lipid peroxidation. ${\beta}-Carbolines$ inhibited degradation of cartilage collagen by $Fe^{2+}$, $H_2O_2$ and ascorbic acid. The reduction of ferricytochrome c due to autoxidation of $Fe^{2+}$, which is inhibited by superoxide dismutase, was not affected by harmaline and harmalol. They also did not have a decomposing action on $H_2O_2$. Hydroxyl radical production in the presence of $Fe^{2+}$ and $H_2O_2$ was inhibited by harmaline, harmalol and DMSO. Harmaline and harmalol may inhibit the oxidative injuries of hyaluronic acid, lipid and cartilage collagen by $Fe^{2+}$ and $H_2O_2$ through their scavenging actions on reactive oxygen species, OH and probably iron-oxygen complexes and exert antioxidant abilities.
천공홀 가압 팽창 개념을 도입한 터널 보조 신공법 연구
조인성,박정준,김종선,이인모,Cho, In-Sung,Park, Jeong-Jun,Kim, Jong-Sun,Lee, In-Mo 한국터널지하공간학회 2010 한국터널지하공간학회논문집 Vol.12 No.6
A new tunnel auxiliary method is proposed in this paper which utilizes the concept of cavity expansion for tuunel reinforcement by forming an umbrella arch on the roof of tunnel. When an inflatable pipe is inserted and expanded by pressure in the bore hole of umbrella arch, the ground around the bore hole can be compacted so that the stress condition above the tunnel perimeter is favorably changed. In order to verify the reinforcement effect of new concept, pilot-scale chamber test, trapdoor test and numerical analysis were performed and compared. In pilot-scale chamber test, three types of inflatable pipes are tested to verify the capability of expansion, and the results arc compared with analytical results obtained by applying cavity expansion theory and with results obtained from finite clement analysis, and the experimental results showed agreeable matches with analytical and numerical ones. Numerical analysis of a tunnel and trapdoor test applied with the inflatable pipes are also performed to figure out the reinforcement effect of the proposed techniques, and the results implied that the new method with 3 directional inflatable pipe (no pressure to downward direction) can contribute to reduce tunnel convergence and face settlement. 현재 널리 적용되고 있는 대표적인 터널보조공법인 강관다단그라우팅공법은 그라우팅 기술을 도입하여 지반의 물성치를 개선하는 개념이나, 풍화토 지반조건에서는 그라우트재 주입 시 입자의 막힘현상으로 주입범위가 극히 제한되어 계획했던 보강 범위 형성이 어려운 문제가 있다. 본 연구에서는 천공홀 가압 팽창 개념을 도입하여 터널 막장면에 Umbrella Type으로 천공홀을 설치하고 팽창형 강관을 삽입하여 터널을 보강하는 신공법에 대한 연구를 수행하였다. 신공법은 삽입된 강관을 팽창시킴으로서 주변 지반 다짐으로 인한 지반응력상태 변화를 유도하고 이로 인하여 터널 굴착에 의한 지반 거동을 안정하게 하는 공법이다. 본 연구에서는 천공홀 팽창으로 인한 주변 지반의 거동을 연구하기 위해서 챔버모형을 실시하였다. 세 가지 형태의 시험적인 팽창관에 대해 팽창 실험을 실시하여 천공홀 벽면에서의 응력과 변위를 이론과 챔버모형실험을 모델링한 수치해석 결과와 실험결과를 비교하였으며, 그 결과가 유사한 것을 확인하였다. 신공법의 터널 보강 효과를 평가하기 위하여 신공법과 강관다단그라우팅공법을 적용한 2차원 터널 수치해석과 Trapdoor 모형토조실험을 수행하였으며, 수치해석 결과와 실험 결과에서 모두 삼방향 팽창형 강관(하부 방향 무가압) 신공법을 적용하였을 경우에 터널 굴착 시 내공변위가 감소하는 결과를 보여주어 신공법의 적용가능성을 확인하였다.
조인성,Cho, In-Sung 한국주조공학회 2022 한국주조공학회지 Vol.42 No.1
In the present paper, the data management of casting processes has been discussed. In order to construct a smart factory in the foundry industry, understanding of the whole casting processes has to be in the first place. Casting process data can be obtained at the kiosk operated by casting engineers and data acquired by sensors in the foundry facility. However, preprocessing of the casting process data must be carried out in order to analyze the casting process by the data. Techniques and some examples for data preprocessing in the foundry was introduced.
조인성,홍준표 ( In Sung Cho,Chun Pyo Hong ) 한국주조공학회 1995 한국주조공학회지 Vol.15 No.2
N/A Solidification of aluminum alloys under moderate pressures has been investigated. Interfacial heat transfer coefficient at the casting/mold interface varies with time after pouring the molten metal into the die cavity, and therefore plays an important role in determining solidification sequence. The heat transfer coefficients were evaluated by using an inverse problem method, based on the measured temperature distribution. The calculated heat transfer coefficients were used for solidification simulation in the squeeze casting process. The effects of applied pressure and positions of insulation in the mold have also been investigated on solidification microstructures and on the formation of macrosegregation of Al-4.5wt.%Cu alloys.
SOLA-VOF 법에 의한 정밀 주형내 용탕흐름의 수치 모델링
조인성,홍준표 ( In Sung Cho,Chun Pyo Hong ) 한국주조공학회 1992 한국주조공학회지 Vol.12 No.5
N/A A numerical model based on the SOLA-VOF method, which can calculate the transient free-surface configuration of the melt, has been developed in order to analyze melt flow in the investment mold. The computational results were compared with experimental results obtained from pure aluminum investment casting. Heat transfer analysis, with and without consideration of melt flow effect has been performed. It can be concluded that analysis of melt flow in the investment mold, provides the optimum conditions for gating design. It also enables more precise solidification simulation, since heat loss, while filling the thin and complex investment mold, plays an important role in determining the solidification sequence.
조인성,홍준표,이호인 ( In Sung Cho,Chun Pyo Hong,Ho In Lee ) 한국주조공학회 1996 한국주조공학회지 Vol.16 No.6
N/A A stochastic model, based on the coupling of the finite volume(FV) method for macroscopic heat flow calculation and a two-dimensional cellular automaton(CA) model for treating microstructural evolution was applied-for the prediction of microstructural evolution in squeeze casting. The interfacial heat transfer coefficient at the casting/die interface was evaluated as a function of time using an inverse problem method in order to provide a quantitative simulation of solidification sequences under high pressure. The effects of casting process variables on the formation of solidification grain structures and on the columnar to equiaxed transition of an Al-4.5wt%Cu alloy in squeeze casting were investigated. The calculated solidification grain structures were in good agreement with those obtained experimentally.
유전자변형생물체의 국가간 이동 등에 관한 법률상의 승인 및 허가의 법리
조인성 ( In Sung Cho ) 한남대학교 과학기술법연구원 2014 과학기술법연구 Vol.20 No.1
Auf die Erteilung der Befreiung besteht grundsaetzlich kein Rechtsanspruch. Bei dieser Fallgruppe spricht man von repressiven Verboten mit Befreiungsvorbehalt oder von Ausnahmebewilligungen. Erfuellt der Antragsteller die gesetzlichen Vorgaben, besteht grundsaetzlich ein Anspuch auf die Erlaubniserteilung. Von dieser Moeglichkeit macht der Gesetzgeber relativ haeufig Gebrauch. Man spricht von praeventiven Verboten mit Erlaubnisvorbehalten oder von Kontrollerlaubnis. Die Polizeigewalt trat in zwei Erscheinungsformen auf, namlich einmal repressiv durch Maßnahmen gegen den Storer(ius politiae) und zum anderen bei von vornherein gefahrlichen Einrichtungen praventiv(ius supremae inspectionis, Oberaufsicht). Aus der polizeilichen Oberaufsicht entstand die Kontrollerlaubnis bzw. das praventive Verbot mit Erlaubnisvorbehalt. In Deutschland war klassisches Beispiel die Genehmigung nach dem fruheren § 16 GewO, auf der nicht nur die luftverkehrsrechtlichen sowie atom- und immissionsschutzrechtlichen Genehmigungen aufbauen, sondern auch die Genehmigungen nach dem GenTG. Die Normstruktur bei praventiven Verbot der Zulassung und Genehmigung im
「朝鮮人民歷史講座」(1950)와 歷史敎育 -樂浪郡의 위치비정을 중심으로-
조인성(Cho, In-Sung) 고려사학회 2021 한국사학보 Vol.- No.83
「조선인민력사강좌」는 사회교육, 성인교육으로서의 의의를 지니는 것이었다. 새로운 국가 건설에 이바지할 수 있도록 인민의 역사의식을 함양하기 위해 기획되었다. 식민주의 역사교육의 폐해를 불식하는 것도 중요한 목표 중 하나였다. 일제시기에는 평양을 중심으로 하는 낙랑군이 420여 년 동안 한반도의 북부를 지배하였다고 가르쳤다. 이는 조선이 일찍이 또 오랫동안 중국의 식민지 내지는 그와 비슷한 처지였다는 歷史像을 교육하여 일본의 식민 지배를 숙명적으로 받아들이게 만들려는 것이었다.「조선인민력사강좌」에서 낙랑군을 비롯한 한사군이 요동에 있었다고 하여 이를 부정하였다. 1950년 전후 북한 역사학계에서는 종래의 ‘낙랑평양설’을 부정하고, 낙랑을 비롯한 한 사군의 위치를 요동에 비정하는 설이 대두하였다. ‘낙랑요동설’은 논쟁의 여지가 있었음에도 불구하고「조선인민력사강좌」에 채택되는 등 정설처럼 되었다. 이는 새로운 국가의 새 서울인 평양이 과거 ‘식민지’의 중심이었다는 것을 꺼렸기 때문이었던 것으로 파악된다. 근대 민족주의의 ‘영토순결주의’에서 벗어나지 못했던 것이다. The “Korean People"s History Lecture” was meaningful as social education and adult education. It was designed to foster the people"s sense of history so that they could contribute to the construction of a new nation. To dispel the evils of colonialist history education was also one of the important goals. During the Japanese colonial period, it was taught that the Lelang Commandery centered on Pyongyang ruled the northern part of the Korean Peninsula over 420 years. This was to educate the history of Joseon"s colonial or similar situation earlier and for a long time, which led to the fatal acceptance of Japanese colonial rule. To overcome this, in the “Korean People"s History Lecture”, it was said that Four Commanderies of Han Dynasty including Lelang Commandery were in Liaodong. Around the 1950s, North Korean historians denied the traditional “LeLang-Pyongyang theory,” and there was a theory that determined the location of the Four Commanderies of Han Dynasty including LeLang in Liaodong. Despite the controversy, it has become the established theory, with it being adopted in the ”Korean People"s History Lecture.” This is understood to have been due to the reluctance that Pyongyang, the new capital of the new country, used to be the center of the “colonial land” in the past. It was captured in the spell of nationalism called "Territorial Purism".
2010년 7월 14일자 독일 CO2의 포집, 저장 및 영구 저장을 위한 기술의 실증 및 응용에 관한법률 초안의 주요 내용과 시사점
조인성 ( In Sung Cho ) 홍익대학교 법학연구소 2014 홍익법학 Vol.15 No.4
Der aktuelle CCS-Gesetzentwurf bleibt mit seiner Beschrankung auf Erprobungs- und Demonstrationsvorhaben hinter dem CO2ATSG-E zuruck. Auf Grund des damit verbundenen Ausschlusses einer großindustriellen Nutzung stellt sich zunachst die Frage der ausreichenden Umsetzung der CCS-Richtlinie, die indes wegen der in den nachsten Jahren im Vordergrund stehenden Erforschung der Wirtschaftlichkeit und Machbarkeit von CCS in der Praxis keine große Rolle spielen durfte. Ungeachtet dessen stellt der Entwurf fur die Erprobung von CCS einen (vorlaufigen) Rechtsrahmen zur Verfugung, der zur Erreichung der mit dem Gesetz verfolgten Zwecke grundsatzlich geeignet ist: Durch die Planfeststellung erhalten die Betreiber von CO2-Leitungen und -Speichern eine starke Rechtsposition, die ihnen Planungssicherheit fur ihre Investitionen bietet; Gleiches gilt mit Blick auf die Rechtswirkungen der Untersuchungsgenehmigung. Außerdem enthalt der Entwurf Vorschriften, die einen hohen Schutzstandard fur Klima, Mensch und Umwelt gewahrleisten. Dies gilt insbesondere mit Blick auf die dynamischen Zulassungs-, Betriebs-, Stilllegungs- und Nachsorgepflichten nach § 13 I 1 Nrn. 2.4 KSpG fur CO2-Speicher: Durch die Forderung nach der Langzeitsicherheit des Speichers werden klimaschadliche CO2-Emissionen aus dem Speicher dauerhaft unterbunden, womit der sich von CCS versprochene Nettoentlastungseffekt erreicht wurde. Mensch und Umwelt werden vor negativen Speicherauswirkungen durch die Gefahrenabwehr- und Vorsorgepflichten des Betreibers wirksam geschutzt. Wesentlich fur die Entscheidung der Unternehmen fur die Erprobung von CCS wird indes sein, ob die derzeit zu beobachtenden Widerstande seitens der Kommunen und in der Bevolkerung ausgeraumt werden konnen. Ansatzpunkte hierfur enthalt der aktuelle Gesetzentwurf mit seiner obligatorischen Behorden- und Offentlichkeitsbeteiligung in den Verfahren zur Planfeststellung von CO2-Leitungen und -Speichern sowie zur Erteilung einer Untersuchungsgenehmigung. Es bleibt abzuwarten, ob dadurch die erforderliche Transparenz vermittelt werden kann, die Voraussetzung fur die Akzeptanz von CCS ist. Auf Seiten der Kommunen konnte die Aussicht auf Ausgleichszahlungen von Speicherbetreibern vor dem Hintergrund leerer Gemeindekassen einen zusatzlichen Anreiz bieten, einer Erprobung der CO2-Speicherung zuzustimmen. Im Ubrigen wird erst die Erprobungsphase zeigen, ob der Einsatz von CCS einen wirksamen und wirtschaftlichen Beitrag zur Reduktion von CO2-Emissionen leisten kann. Dabei wird neben der Realisierbarkeit einer dauerhaften und vollstandigen Speicherdichtigkeit auch zu beobachten sein, inwieweit Burokratiekosten fur die umfassenden Uberwachungspflichten der Speicherbetreiber und der zustandigen Behorden sowie die Aufwendungen fur Deckungsvorsorge und Nachsorgebeitrag zu unzumutbaren Belastungen der Unternehmen fuhren.