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Al-xSi-2Cu-1Mg/ySiC(x:6 , 12 , 18. y:0∼10wt.%) 계 복합재료의 열적성질에 관한 연구
박상준,조원용,강세선,임윤수,권혁무,윤의박 ( Sang Joon Park,Won Yong Jo,Se Seon Kang,Yoon Su Lim,Hyuk Mu Kwon,Eui Park Yoon ) 한국주조공학회 1993 한국주조공학회지 Vol.13 No.4
N/A The purpose of this study is to obtain basic information on the particle dispersion, the coefficient of thermal expansion and the thermal conductivity of compocasted Al-xSi-2Cu-1Mg/ySiC(x:6, 12, 18. y: 0∼10wt.%) composite. With increasing the content of SiC particles, the thermal expension coefficient and the thermal conductivity decrease. The coefficient of thermal expension between 20 and 300℃ is 21.3×10^(-6)/℃∼ 18.0×10^(-6)/℃ for the Al-Si alloys and 18.4×10^(-6)/℃∼16.0×10^(-6)/℃ for the composite with 10wt. % SiC. The thermal conductivity at 300℃ is 121∼169W·m^(-1)·k^(-1) for the Al-Si alloys and 114∼159W·m^(-1)·k^(-1) for the composite with 10wt. % SiC.
말기신부전 환자에서 투석치료의 시작이 염증상태 및 면역반응에 미치는 영향에 관한 연구
이재원 ( Jae Won Lee ),김혜원 ( Hye Won Kim ),박은범 ( Eun Bum Park ),부창수 ( Chang Su Boo ),고강지 ( Gang Jee Ko ),조상경 ( Sang Kyung Jo ),조원용 ( Won Yong Cho ),김형규 ( Hyoung Kyu Kim ) 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.5
Purpose : inflammation is a common feature in chronic kidney disease patients, and it could contribute to long-term morbidity and mortality related with malnutrition and atherosclerosis. In this study, we aimed to investigate the effect of initiating dialysis on inflammatory state, nutritional parameter, and immune response in end-stage renal disease (ESRD) patients. Methods : 57 ESRD patients who initiated hemodialysis (HD, n=31) or continuous ambulatory peritoneal dialysis (CAPD, n=26) were enrolled. Pro-inflammatory cytokine, tumor necrosis factor (TNF)-α, and anti-inflammatory cytokines, interleukin (IL)-10 and adiponectin were measured before and 3 months after initiation of dialysis. Inflammatory marker, highly sensitive C-reactive protein (hs-CRP), and nutritional parameter, albumin, were also checked. Lipopolysaccharide (LPS)-stimulated production of TNF-α and IL-10 were measured for the evaluation of immune response by external stimuli. Results : As uremia was reduced by initiating dialysis, serum level of TNF-α was decreased and adiponectin was increased. These changes were accompanied by the decrease of hs-CRP and the increase of serum albumin. LPS-stimulated cytokines production was increased after initiating dialysis. There differences in these parameters comparing HD and CAPD patients except more increase of serum adiponectin level in CAPD patients. Conclusion : Our study demonstrated that initiation of dialysis results in decrease of inflammation, improvement of nutritional status, and restoration of proper immune responsiveness in ESRD patients. These results suggest that correction of uremic milieu through dialysis has beneficial effects. Therefore, initiation of dialysis might have the advantage of improving inflammatory and nutritional status, and correcting immune dysfunction in ESRD patients.
신장 이식 환자에서 CMV duodenitis 치료 후 병발한 Pneumocystis jirovecii 폐렴 1예
김혜원 ( Hye Won Kim ),김명규 ( Myung Gyu Kim ),우영석 ( Young Seok Woo ),부창수 ( Cang Soo Boo ),조상경 ( Sang Kyung Jo ),김형규 ( Hyoung Kyu Kim ),조원용 ( Won Yong Jo ),이광균 ( Kwang Gyun Lee ),김혜옥 ( Hye Ok Kim ),오초롱 ( C 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.5
Solid organ transplant recipients are at increased risk for various opportunistic infections because of their immunocompromised state. Pneumocystis jirovecii (carinii) infection has posed serious problems in these patients which can be life threatening. It has been reported that incidences of Pneumocystis infection have dramatically decreased with the use of prophylactic antibiotics. However, there have been reports that say the risks of Pneumocystis infection are increasing with the use of new immunosuppressive drugs and in presence of preceding immunomodulating infections such as CMV infection which is another common opportunistic infection in transplant patients. There were only a few case reports abroad on Pneumocystis infection following CMV infection in patients who underwent kidney transplantation. In Korea, however, there hasnt been any report of such cases. Herein we report a case of a kidney transplant patient who experienced a serious episode of Pneumocystis jirovecii pneumonia following CMV duodenitis. After adequate mechanical ventilation and use of antibiotics the patient completely recovered without any complications.