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성인에서 발견된 비정형 샘 증식증과 동반된 폐의 선천성 낭성 선종양 기형
이호성 ( Ho Sung Lee ),최재성 ( Jae Sung Choi ),서기현 ( Ki Hyun Seo ),나주옥 ( Ju Ock Na ),김용훈 ( Yong Hoon Kim ),오미혜 ( Mi Hye Oh ),조성식 ( Sung Shick Jou ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.66 No.5
Congenital cystic adenomatoid malformation (CCAM), which is classified into five types according to size and bronchial invasion, is a rare type of developmental anomaly of the lung. CCAM is occasionally accompanied by malignancy, such as bronchioloalveolar carcinoma (BAC) or rhabdomyosarcoma. As defined by the WHO, atypical adenomatous hyperplasia (AAH) is a non-invasive spread of atypical epithelial cells in single rows along the alveolar wall, within a lesion that is usually less than 5 mm in diameter. AAH was also regarded as a pre-invasive neoplasia, especially associated with BAC and adenocarcinoma. We report a case of type II CCAM with AAH in adults, with a review of the references.
증례 : 호흡기 ; 양성 전이성 폐 평활근종의 자연 경과
박재만 ( Jae Man Park ),최재성 ( Jae Sung Choi ),나주옥 ( Ju Ock Na ),김용훈 ( Yong Hoon Kim ),서기현 ( Ki Hyun Seo ),오미혜 ( Mi Hye Oh ),조성식 ( Sung Shick Jou ) 대한내과학회 2011 대한내과학회지 Vol.81 No.3
폐에 발생하는 양성 전이성 근종은 과거 자궁 절제술이나 근종 절제술을 시행 받은 가임기 여성에게 호발하는 드문 질환으로 악성의 임상 특징을 가진다. 대부분 무증상이나 일부에서는 마른 기침이나 흉통, 호흡곤란 및 심한 경우 호흡 부전까지 발생하는 등 여러 가지 임상양상을 가진다. 치료는 본 질환이 여성 호르몬과 관련 있어 여성 호르몬을 소실시키는 방법을 주로 사용하고 있다. 저자들은 자궁 절제술과 근종절제술을 시행받은 기왕력이 있는 여성에서 발생한 양성 전이성 폐평활근종 각각 1예를 경험하여 문헌고찰과 함께 보고하는 바이다. Benign metastasizing pulmonary leiomyoma is a rare disease that is usually detected several years after hysterectomy or myomectomy. Recently, we experienced two cases, one with monthly chest pain and the other without symptoms, which were diagnosed with benign metastasizing leiomyoma in the lung. A 48-year-old woman who underwent hysterectomy 12 years earlier was referred to us because of multiple pulmonary nodules on chest radiography, and chest pain for 6 months. Thoracoscopic tumor excision was performed. Pathologically, she was diagnosed with benign metastasizing leiomyoma in the lung. After that, chest computed tomography showed tumors with a progressive reduction in size. The other 48-year-old woman, who had undergone myomectomy for uterine leiomyoma 8 years before, visited our hospital for evaluation of incidentally revealed bilateral multiple nodules on chest radiography. The microscopic finding of percutaneous transthoracic needle biopsy revealed a benign pulmonary metastasizing leiomyoma originating from uterine leiomyoma. Multiple nodules on chest radiography were more increased than those performed 1 year and 3 months prior to admission. However, chest X-ray showed tumors that had progressively decreased in size at 6 months after diagnosis of menopause. (Korean J Med 2011;81:387-392)
근치적 수술 후 소장으로 단독 전이된 폐의 다형성 암종
김기원 ( Ki Won Kim ),이호성 ( Ho Sung Lee ),최재성 ( Jae Sung Choi ),서기현 ( Ki Hyun Seo ),오미혜 ( Mee Hye Oh ),조성식 ( Sung Shick Jou ),김용훈 ( Yong Hoon Kim ),나주옥 ( Ju Ock Na ) 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.2
Small bowel metastasis of pleomorphic carcinoma of the lung is very rare. A 58-year-old man was admitted to our hospital with abdominal palpable mass in the right upper quadrant area. He underwent right middle and lower lobectomy for early stage pleomorphic carcinoma of the lung approximately 3 months ago. USG-guided biopsy was performed for abdominal mass. Pathologic examination revealed a metastatic pleomorphic carcinoma from the lung. He received chemotherapy followed by radiation therapy but died due to septic shock caused by intestinal stenosis and adhesion. We report the first case of small bowel metastasis by pleomorphic carcinoma of the lung after curative surgery.