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조미연,이광길,이기범,정현주,정우희,Cho, Mee-Yon,Lee, Kwang-Gil,Lee, Kyi-Beom,Jeong, Hyeun-Joo,Jung, Woo-Hee 대한세포병리학회 1990 대한세포병리학회지 Vol.1 No.1
We present the cytologic features of a case of solid and papillary neoplasm of the pancreas. Cytologically, the tumor was composed of a monotonous population of polygonal cells containing eccentrically located round nuclei with one or two distinct small nucleoli and a finely stippled chromatin pattern. The tumor cells were similar to those of the islet cell tumor and showed isolated loosely aggregated and solid sheets or large cell clumps. The large cell clumps revealed a branching papillary structure containing fibrovascular central core, which is characteristic histologic feature of solid and papillary neoplasm of the pancreas. This case was confirmed by tissue examination including histochemical, immunohistochemical and electron microscopical studies. Ultrastructurally, the tumor cells contained a few membrane- bound electron dense granules.
악성 흉선종의 세침흡인 세포학적 소견 - 침윤성 흉선종 2례와 흉선암종 2례 -
조미연,박영년,이광길,Cho, Mee-Yon,Park, Young-Nyun,Lee, Kwang-Gil 대한세포병리학회 1991 대한세포병리학회지 Vol.2 No.1
We report 4 cases of malignant thymoma which were composed of 2 cases of invasive thymoma and 2 cases of thymic carcinoma. The cytologic findings of invasive thymoma were similar to those of benign thymoma. The distinctive cytologic features of thymic carcinoma were necrotic background, irregular clusters and individually scattered arrangement of anaplastic epithelial cells, and some scattered mature small lymphocytes. These findings may be found in the Hodgkin's lymphoma, seminoma, and metastatic squamous ceil carcinoma, undifferentiated carcinoma, and large ceil carcinoma of the lung. But, the feature of irregular clustering of anaplastic epithelial cell haying scanty cytoplasm was different from Hodgkin's lymphoma and seminoma. Clinical and radiologic findings as well as cytologic finding were helpful in differential diagnosis of thymic carcinoma from metastatic carcinoma.
경추에 발생한 척삭종의 세침흡인 세포학적 소견 - 1예 보고 -
양경무,조미연,정순희,봉정표,Yang, Kyung-Moo,Cho, Mee-Yon,Jung, Soon-Hee,Bong, Jeong-Pyo 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.1
A case of cervical chordoma diagnosed by fine needle aspiration is discussed. A 41year-old male was admitted due to dyspnea on neck flexion. Radiologic image revealed a retrotracheal superior mediastinal solid mass. Aspiration cytology showed many clusters of oval or large polygonal cells having abundant eosinophilic or bubbly cytoplasm in an amorphous blue-gray mucoid background. The nuclei were round and showed size variation, coarse granular chromatin, and indistinct nucleoli. Some cells contained brown granular pigments in the cytoplasm. Mitoses were rarely found. The cytoplasm was strongly positive for PAS stain. Immunohistochemical stains using cell block revealed positive reaction for cytokerain, EMA, vimentin, and S-100 protein. The confirmative diagnosis was made by following excisional biopsy. Electron microscopic study revealed large pools of intracytoplasmic glycogen and microfilaments. This is the first case of cervical chordoma diagnosed by aspiration cytology to our knowledge in Korean literature.
늑골에 발생한 맥관육종의 세침흡인 세포학적 소견 - 1예 보고 -
김희정,조미연,정순희,이광길,Kim, Hee-Jung,Cho, Mee-Yon,Jung, Soon-Hee,Lee, Kwang-Gil 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.2
Angiosarcoma of the bone is rare with an incidence of 0.13%. It may be solitary or multiple. Its cytologic findings by FNA have rarely been reported. We report a case of angiosarcoma of the rib in a 66 year-old man. FNA revealed single or clusters of round to oval shaped cells in a hemorrhagic and myxoid background. The large central nuclei had irregular nuclear membrane, chromatin clumping and prominent nucleoli. The cytoplasm was scanty with an eosinophilic distinct cytoplasmic border. Erythrophagocytosis by malignant cells was also found. Histopathologic examination confirmed the diagnosis of angiosarcoma revealing irregular and complex anastomosing vascular channels lined by malignant round tumor cells, protruding into the lumen. Immunohistochemical staining revealed diffuse strong positive reaction to factor VIII-related antigen and CD31.
김건욱(Kuhn Uk Kim),조미연(Mee Yon Cho),조남천(Nam Cheon Cho),윤광수(Kwang Soo Yoon),김대성(Dae Sung Kim),노병선(Byoung Seon Rhoe) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5
Adenosquamous carcinoma of the pancreas has a mixture of adenocarcinoma and squamous cell carcinoma components and is uncommon. We presents one case of adenosquamous carci- noma of the pancreas in old man aged 76. His chief cornplains were intermittent abdorninal discomfort and pain. Physical examination revealed huge abdominal mass in left upper quad- rant abdomen. All laboratory data were not significant. Abdominal ultrasonography and CT scan revealed a well demarcated cystic and solid mass which was located at the tail of the pancreas. Successful resection of the tumor by splenectomy, total gastrectomy and segmental resection of transverse colon were carried out. Cut section of the resected specimen reveals a huge cyst locating between the serosal surface of the stomach and pancreas and an oval round solid mass with infiltrating margin of the distal pancreas. Histopathologically, the tumor was composed of adenocarcinorna, well differentiated squamous cell carcinoma and anaplastic car- cinoma with transition areas. The cyst was partly lined by mesothelial cells and poorly differentiated squamous cell carcinoma. The patient was discharged without specific prob- lem. But he died 6 months after operation.(Korean J Gastroenterol 1994; 26: 885 891)
유수영(Soo Young Yoo),김건욱(Kuhn Uk Kim),조미연(Mee Yon Cho) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.6
Infantile hemangioendothelioma of the liver is an uncomrnon tumor, either solitary or multicentric. Congestive heart failure is commonly associated with the tumor because the vascular lesions can act as arteriovenous fistula. The patient with multicentric lesions usually presents in infancy with hepatomegaly and high output congestive heart failure. Scilitary hepatic hemangioendothelioma has better prognosis because of lower incidence of congestive heart failure. Computerized tomography and arteriography are diagnostic. A variety of approaches to treatment including resection, radiation, steroid therapy, hepatic artery ligation and embolization have been tried, but those treatments were not uniformly successful. We report two infants with solitary hepatic hemangioendothelioma completely resected. The only symptom of the tumor was a palpable mass felt shortly after birth. Fortunately, both patients had tumors well localized in the left lobe of the liver. I.eft hepatic lobectomy was performed in both cases without serious morbidity
황성관,박희전,윤여승,나중호,오진록,김기호,김동진,양경무,조미연,Hwang, Sung-Kwan,Park, Heui-Jeon,Yoon, Yeo-Seung,Rha, Jung-Ho,Oh, Jin-Rok,Kim, Ki-Ho,Kim, Dong-Jin,Yang, Kyung-Moo,Cho, Mee-Yon 대한근골격종양학회 1998 대한골관절종양학회지 Vol.4 No.1
Osteosarcoma is the most common primary bone tumor except for multiple myeloma. Hematogenous spread of osteosarcoma presents the t1susal route of dissemination. Lung metastasis is the most common, however the lymph node involvement is quite rare. In addition, according to Mirra, radiologically detectable involvement of lymph node is an extremely rare manifestation of osteosarcoma. The authors had experienced a patient with an osteosarcoma of the right distal femur which spread to the right inguinal lymph node and lung. After preoperative chemotheraphy, a limb salvage operation was performed around the lesion of right distal femur and the right inguinal lymph nodes were dissected. A adjuvant postoperative chemotheraphy was performed. After the treatment, there was no recurrence of osteosarcoma or any other metastatic evidence for two years and 8 months.
제 I 형 신경섬유종증에 병발하였던 종격동내 횡문근육종에 의한 척수압박 1례 - 증례보고 -
김세윤,황금,홍순기,변진수,허철,김헌주,한용표,이명섭,이종국,조미연,Kim, Sei-Yoon,Whang, Kum,Hong, Soon-Ki,Pyen, Jhin-Soo,Hu, Chul,Kim, Hun-Joo,Han, Young-Pyo,Lee, Myoung-Sup,Lee, Chong-Kook,Cho, Mee-Yon 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.5
A 12-years-old female admitted to the hospital with the complaint of pain on the right upper chest area which persisted about 1 month prior to admission. $Caf{\acute{e}}$-au-lait spots of various size laying on a whole body and freckling on the axilla were found on physical examination. A huge mass was found on the plain chest X-ray and on chest MRI. The mass encroached thoracic spine, posterior rib, back muscles, and then into the neural canal and compressed thoracic spinal cord. On the 5th day of hospitalization, the patient complained tingling on the both legs and 2 days later, monoparesis on the right leg. Open thoracotomy and decompressive laminectomy was done to remove mass. Pathologic reports confirmed rhabdomyosarcoma, embryonal type.