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- 저자 : 정현도(Hyundo Jeong) (검색결과 3 건)
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Gadoteridol을 이용한 Head & Neck MR Angiography에서의 적정 Flip Angle
정현근(Hyunkeun Jeong),김민기(Mingi Kim),송재준(Jaejun Song),남기창(Kichang Nam),최현성(Hyunsung Choi),정현도(Hyundo Jeong),김호철(Hochul Kim) 대한전자공학회 2016 전자공학회논문지 Vol.53 No.3
본 연구의 목적은 가돌리늄 조영제를 사용한 Head & Neck MR Angio검사에 있어서 매개변수인 FA(Flip Angle)이 MR신호에 미치는 영향에 대해서 알아보고자 하였으며, 이에 따른 FA의 적정 값을 제시하는 것이다. 실험은 FA증가에 따른 MR팬텀실험과 임상실험으로 진행하였고, 이에 대한 정량적 분석이 이루어졌다. 실험결과 팬텀실험에서의 조영증강 반응시작 지점인 RSP(Reaction Starting Point)는 FA증가에 따라 300∼400 m㏖ 사이에서 반응하였고, 최대 신호강도인 MPSI(Max Peak Signal Intensity)는 2,086, 3,705, 5,109, 6,194, 7.096, 7,192 [a.u]를 기록하였다. MPSI가 형성되는 몰농도 지점인 MPP(Max Peak Point)는 FA에 증가에 따라 40, 50, 50, 40, 50, 40 mmol에서 보였으며, MPSI의 증가율인 IRMPSI(Increase Rate of MPSI)는 77.6%, 37.9%, 21.2%, 14.6%, 1.4%임을 확인하였다. 임상실험에서의 평가기준인 SICB(Signal Intensity of Carotid artery Bifurcation)는 FA증가에 따라 각 평균값 2392.5, 4165.2, 4270, 3502.2, 3263.7, 3119.6 [a.u]를 기록하였고, 아티팩트 발생율인 ORA(Occurence Rate of Artifact)는 0, 0, 20, 40, 50, 70%로 점차 증가하였다. 본 연구를 통하여 FA의 증가는 혈관 내가돌리늄과 결합한 H1스핀의 신호강도와 아티팩트에 영향을 미친다는 사실을 확인하였고, 이는 실제 임상에서의 CE(Contrast Enhanced)-Head&Neck MR Angio검사에 있어서 본 연구의 데이터를 활용한다면 진단학적으로 효율적인 MR Angiography 영상을 구현할 수 있을 것으로 사료된다. In this research, we tried to suggest moderate FA(Flip Angle) for CE(Contrast Enhnaced)-Head&Neck MR Angiography with Gadoteridol. For this study, we did test MR phantom and clinical study according to FA change. After that, quantitative analysis was progressed. The results of MR phantom study were as follow: RSP(Reaction Starting Point)was recorded within 300∼400 m㏖. MPSI(Max Peak Signal Intensity) was 2,086, 3,705, 5,109, 6,194, 7.096, 7,192 [a.u]. MPP(Max Peak Point) was shown at 30, 50, 50, 40, 50, 40 mmol. IRMPSI(Increase Rate of MPSI) was 77.6%, 37.9%, 21.2%, 14.6%, 1.4% as increasing of FA. The results of clinical study were as follow SICB(Signal Intensity of Carotid artery Bifurcation) was recorded respectively 392.5, 4165.2, 4270, 3502.2, 3263.7, 3119.6 [a.u]. ORA(Occurence Rate of Artifact) was increased as 0, 0, 20, 40, 50, 70%. According to this research, we are not only able to assure that increase of FA can be effect on H1 spin"s SI(Signal Intensity) which was combined with gadolinium agent, but also be effect on artifact rate in blood vessel. In clinical field, we expect that CE-Head&Neck MR Angiography can be performed in a practical way with this research.
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9.4T MRI FLASH Sequence에서 마우스의 뇌 조영증강 검사를 위한 적정 Echo phase
정현근(Hyunkeun Jeong),김민기(Mingi Kim),남기창(Kichang Nam),정현도(Hyundo Jung),안치권(Chigwon Ahn),김호철(Hochul Kim) 대한전자공학회 2017 전자공학회논문지 Vol.54 No.7
본 연구에서는 9.4T MRI의 FLASH 시퀀스를 이용하여 마우스의 뇌 조영증강 검사 시 적정한 echo phase를 알아보고자 하였다. 이에 따른 정량화를 위하여 가도테리돌로 제작된 MR팬텀 실험을 진행하였다, 서로 다른 몰 농도의 가돌리늄으로 구성된 각 세 개의 팬텀을 제작하여 마우스 뇌 검사에 사용하고 있는 FLASH 시퀀스의 echo phase에 변화를 주어 시행한 후, 이에 대한 분석을 진행하였다. 팬텀실험결과 SSI(Saline"s Signal Intensity)는 6π부터 28π까지 33개 각각의 phase에서 25~27[a.u]를 보였고, RSP(Response Start Point)는 각각 30~100 mmol을 기록하였다. MPSI(Max Peak Signal Intensity)는 47~52 [a.u]를 보였고, MPP(Max Peak Point)는 0.8~9 mmol로 기록되었다. EPMS(Enhancement Percentage of MSI to SSI)는 80.8~108.0%로 기록되었고, ASIMP(Average of SI according to Mol concentration on each Phase)은 21.1~31.8 [a.u] 사이에서 형성되었다. 마지막으로 ORA(Occurence Rate of Artifact)는 아티팩트 발생유무에 따라 +1과 -1로 표기하였다. 본 연구를 통하여 9.4T MRI에서의 FLASH 시퀀스의 조영증강 정도를 정량화 할 수 있었고, 마우스의 뇌 조영증강 검사 시 적정 echo phase를 산출 할 수 있었다. The objective of study was to investigate the optimal echo phase for mouse brain enhancement scan using fast low angle shot (FLASH) sequence of 9.4T magnetic resonance imaging (MRI). For quantification based on this method, an MR phantom experiment and clinical research were done. The phantom experiment was conducted by fabricating three phantoms with different molar concentration of gadolinium to create changes in echo phase of 9.4T FLASH sequence used in mouse brain scans. In the phantom experiment, SSI was 25~27 [arbitrary units, a.u.] in each of 33 phases from 6π to 28π, while RSP was 30~100 mmol. MPSI was 47~52 [a.u], while MPP, where MPSI is seen, was 0.8~9 mmol. EPMS was 80.8~108.0%, while ASIMP was formed between 21.1 and 31.8 [a.u]. In the clinical research, Finally, the occurrence rate of artifact that expressed -1 nd +1. The present study was able to quantify the degree of enhancement at FLASH sequence of 9.4T MRI, as well as identify the optimal echo phase during mouse brain enhancement scan.
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제주의 양식 넙치(Paralichthys olivaceus)를 대상으로 한여윔증 모니터링(2010-2013)
김승민 ( Sungmin Kim ),전려진 ( Lyujin Jun ),박명애 ( Myoungae Park ),정승희 ( Sunghee Jung ),정현도 ( Hyundo Jeong ),정준범 ( Joonbum Jeong ) 한국수산과학회(구 한국수산학회) 2015 한국수산과학회지 Vol.48 No.5
In this study aiming at the cultured olive flounders in Jeju island of Korea, has performed a total of 216 cases of pathogen tests for the olive flounders which seemingly had the symptom of emaciation in 24 farms on the suspicion of its occurrence from June 2010 to December 2013 and intended to get the basic information about the pathogen. According to the survey results of the emaciation infection status of 24 farms in Jeju over the period of this survey, it was confirmed that 18 (75%) of 24 farms in Jeju are positive in the emaciation infection. Among them, as for the rate of infection per year, it was observed that they are 38% in 2010, 48% in 2011, 50% in 2012 and 60% in 2013, and over the period of this survey the infection rate in accordance with the temperature of water has observed a variety of incidence rates from the summer to the winter season. In addition, according to the results of emaciation infection status for each size, the equivalent showed a detection rate, 54% in 11-20 cm, 43.9% in 21-30 cm and 25.4% in over 31 cm. This result accounts for an important portion among the diseases of farmed olive flounders in Jeju, is considered to be one of the diseases which cause troubles in the farms for olive flounders on land and it is thought that it can be utilized as basic data in order to estimate emaciation which may occur in the similar size of the cultured olive flounders in Jeju island.
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