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1% 프레드니솔론과 0.1% 브롬페낙 점안액의 백내장 수술 후 낭포황반부종 예방 효과 비교
정현교(Hyun Kyo Jeong),신우범(Woo Beom Shin),서경률(Kyoung Yul Seo),이제훈(Jei hoon Lee) 대한안과학회 2016 대한안과학회지 Vol.57 No.12
목적: 백내장 수술 후 염증 조절을 위해 사용한 1% Prednisolone 점안약과 0.1% Bromfenac 점안약의 낭포황반부종 예방 효과를 비교하였다. 대상과 방법: 2013년 7월부터 2016년 1월까지 연세대학교 세브란스병원에서 단일 술자에게 백내장 수술을 받은 349안을 대상으로 후향적 의무기록 분석을 시행하였다. 술 후 1일, 1주, 1달째 시력, 안압 측정 및 굴절검사, 세극등 현미경검사를 시행하였다. 술 후 1달의 최대교정시력이 0.5 이하(logMAR ≥ 0.3)로 측정되는 환자에서 빛간섭단층촬영을 시행하여 낭포황반부종의 발생 여부를 확인하였다. 결과: 총 349안 중 192안에서 1% Prednisolone 점안약을, 157안에서 0.1% Bromfenac 점안약을 사용하였다. 두 군 사이에 환자들의 평균 연령(p=0.708), 성비(p=0.977), 수술 받은 눈의 방향(p=0.443)은 유의미한 차이를 보이지 않았다. 수술 1달 후 최대교정시력은 각각 0.04 ± 0.09, 0.03 ± 0.07로 두 그룹 간의 차이는 없었으며(p=0.947) 두 그룹 모두 수술 후 시력 호전을 보였다(p<0.001, p<0.001). 스테로이드 군 1안에서 수술 후 낭포황반부종이 발생하였고, 3안에서 30 mmHg 이상의 안압 상승이 관찰되었다. Nonsteroidal anti-inflammatory drug (NSAID) 군에서는 안압 상승이나 낭포황반부종의 발생은 관찰되지 않았다. 결론: 백내장 수술 후 낭포황반부종의 발생률은 1% Prednisolone 점안약을 사용한 군과 0.1% Bromfenac 점안약을 사용한 군에서 의미 있는 차이가 없었다. 따라서 스테로이드의 부작용을 고려해 볼 때, 백내장 수술 후 염증 조절 및 낭포황반부종을 예방하기 위한 약제로 NSAID의 단독 사용도 고려할 수 있을 것으로 보인다. Purpose: To compare the clinical effectiveness of 1% Prednisolone acetate ophthalmic solution and 0.1% Bromfenac sodium hydrate ophthalmic solution on prevention of cystoid macular edema after cataract surgery. Methods: A retrospective chart review of 349 patients who received phacoemulsification with intraocular lens implantation in Severance Hospital from July 2013 to January 2016 was performed. In these patients, 192 eyes received 1% Prednisolone acetate ophthalmic solution, and 157 eyes were treated with topical 0.1% Bromfenac sodium hydrate ophthalmic solution. The incidence and severity of cystoid macular edema (CME) were evaluated by retinal foveal thickness on optical coherence tomography for patients who showed best corrected visual acuity (BCVA) less than 0.5 (log MAR ≥ 0.3). Results: There was no significant difference between the two groups in age (p = 0.708), sex (p = 0.977), or the side of operated eye (p = 0.443). The two groups showed BCVA 0.04 ± 0.09 (Steroid group) and 0.03 ± 0.07 (nonsteroidal anti-inflammatory drug [NSAID] group) at 1 month after the surgery and the difference was not significant (p = 0.947). One eye in the topical steroid group had cystoid macular edema, and 3 eyes in the steroid group showed elevated intraocular pressure (IOP) over 30 mm Hg. There were no IOP elevations or macular edema in the NSAID group. Conclusions: The results showed that 0.1% Bromfenac sodium hydrate ophthalmic solution had a similar effect to 1% Prednisolone acetate ophthalmic solution on preventing CME after cataract surgery. This indicates that topical NSAID can be considered along with topical steroids in order to prevent CME after cataract surgery.
단안 삼출성 나이관련황반변성 환자의 무증상 반대안의 외망막층 두께 변화
정현교(Hyun Kyo Jeong),김성수(Sung Soo Kim),박현주(Hyun Ju Park) 대한안과학회 2017 대한안과학회지 Vol.58 No.9
Purpose: To compare the outer retinal thickness in normal fellow eyes of patients with unilateral age-related macular degeneration (AMD) and normal control eyes. Methods: We retrospectively reviewed the medical records of 60 patients with unilateral exudative AMD including polypoidal choroidal vasculopathy and 60 normal controls. Spectralis optical coherence tomography was performed in the normal fellow eyes of patients with unilateral AMD and in the normal group. The thicknesses between the retinal pigment epithelium (RPE) line and the cone outer segment tips (COST) line, between the COST line and the photoreceptor inner segment/outer segment (IS/OS) line, and between the IS/OS line and the external limiting membrane (ELM) line were measured at the fovea in both groups. Results: The thickness between the RPE and COST lines was 32.4 ± 3.0 μm in normal fellow eyes of patients with unilateral AMD and 35.3 ± 3.5 μm in the normal group (p < 0.001). Total retinal thickness, thicknesses between the COST and the IS/OS lines and the IS/OS and the ELM lines in fellow eyes were not significantly different from those of normal eyes (p = 0.126, 0.615, 0.874). There was no significant difference in total retinal thickness or each outer retinal thickness measured in normal fellow eyes between patients with neovascular AMD and polypoidal choroidal vasculopathy. Conclusions: The thickness between the RPE and the COST lines was thinner in the fellow eyes of patients with unilateral AMD than in the normal eyes. We suggest that less thickness between the RPE and COST lines might indicate a greater risk of AMD. J Korean Ophthalmol Soc 2017;58(9):1036-1041
박정태(Jeong-Tae Park),정현교(Hyun-Kyo Jung) 한국자기학회 1997 韓國磁氣學會誌 Vol.7 No.2
In this paper, the application of fuzzy decision to optimization of induction motor design is proposed. This method can reflect the designer’s experience, view, and judgment, but also can be applied to multi-objective optimization design easily. The electromagnetic performance of the induction motor are calculated by means of the equivalent magnetic circuit method. The design method is the D²L method which is combined with fuzzy decision and optimization algorithm. As the optimization algorithm, the evolution strategy (ES) is applied. The proposed algorithm is applied to a multiobjective optimization of an induction motor design where the motor should have less weight and, at the same time, have higher efficiency and power factor at rated operating points.
225AF 배선용 차단기를 위한 전자식 액추에이터 설계 및 해석
박현정(Hyeon-Jeong Park),김소현(So-Hyun Kim),노종석(Jong-Suk Ro),정현교(Hyun-Kyo Jung) 대한전기학회 2014 대한전기학회 학술대회 논문집 Vol.2014 No.4
기존 배선용 차단기는 바이메탈이나 스프링을 이용한 기계식 매커니즘으로 구동을 하였다. 이러한 기계식 매커니즘은 가격이 저렴한 반면, 원격 개폐가 어려운 단점을 가진다. 이러한 문제를 해결하기 위해, 본 논문에선 배선용 차단기에 기존 전자식 액추에이터의 한 종류인 SPMA(Separated Permanent Magnet Actuator)를 적용하였고, 225AF 용량에 대하여 설계 및 해석을 진행하였다. 설계된 모델의 해석 기법은 실험을 통해 검증하였다.