악안면 영역의 Castleman's disease의 치험례

정인교,김욱규,신상훈,박혜련,이의훈,장원석,Chung, In-Kyo,Kim, Uk-Kyu,Shin, Sang-Hoon,Park, Hye-Ryun,Lee, Eui-Hoon,Jang, Won-Seok 대한구강악안면외과학회 2001 대한구강악안면외과학회지 Vol.27 No.5

본 교실에서는 우측 악하부와 우측 안와 하부의 종창으로 내원한 53세 여자 환자에서 Fine Needle Aspiration Biopsy로 림프절의 반응성 과증식으로 진단되어 다시 절제 생검을 시행하여 multi-centric Castleman's disease로 진단하였다. 조직 검사상 유리질 혈관형과 형질세포형이 공존하는 복합형으로 나타났으며 병소의 적출술만을 시행한 후 1년이 지난 지금까지는 별다른 소견없이 좋은 경과를 나타내고 있으며 앞으로도 계속 주의깊은 관찰이 필요로 한다. Castleman's disease or angiofollicular lymph node hyperplasia, is a rare lymphoproliferative disorder. It may be appear as a local or generalized tumor-like condition, usually in chest or abdomen and may involve both lymph nodes and non-nodal tissues. Castleman's disease is an unusal entity which may at times mimic malignancy but is entirely benign in nature. It is topical as it has been noted to occur with AIDS and Kaposi's sarcoma. Careful interpretation of radiogram may help to distinguish Castleman's disease from other tumor condition, such as lymphoma, neurogenic tumor, or even angiofibroma, etc. But exact diagnosis must be made on the basis of histologic confirmation. In addition to histologic features, clinical distinction between the localized and multicentric form is important in selecting appropriate management. Surgical excision of an localized mass is the first choice of treatment. Partial resection, radiotherapy or observation alone may avoid the need for exessively aggressive therapy. Patients with multicentric disease don't benefit by surgical management because of systemic manifestation and rapid deterioration. Thus, antineoplastic agents and steroids may offer an alternative form of therapy. We report a case of female patient with Castleman's disease in oral and maxillofacial region, treated by surgical excision with good results.

부산시 일원의 토양 오염도 조사

정인교,홍성수,윤일,Chung, In-Kyo,Hong, Seong-Soo,Yun, Il 대한약학회 1994 약학회지 Vol.38 No.6

To provide a basis for setting up an environmental pollution policy of Pusan, an investigation of metal contents in the soil of Pusan was carried out from May, 1993 to April, 1994. Soil was sampled from 10 sites of industrial area,8 sites of commercial area, 8 sites of residential area, 8 sites of green area and 8 sites of agricultural area. The industrial area was the most heavily polluted and the average contents of Cd, Cu, Zn, Mn, Pb and As were 0.580, 19.377, 67.348, 59.638, 58.555 and 1.006 ppm, respectively. In the soil of commercial area, the average contents of Cd, Cu, Zn, Mn, Pb and As were 0.453, 19.110, 63.384, 56.006, 37.466 and 0.578 ppm, respectively, and the average contents of Cd, Cu, Zn, Mn, Pb and As were 0.289, 10.312, 55.246, 55.536, 17.695 and 0.610 ppm, respectively, in the soil of residential area. The green area was the least polluted and the average contents of Cd, Cu, Zn, Mn, Pb and As were 0.215, 5.949, 19.366, 37.244, 6.856 and 0.295 ppm, respectively. In the soil of agricultural area, the average contents of Cd, Cu, Zn, Mn, Pb and As were 0.160, 7.077, 25.365, 51.485, 10.607 and 0.499 ppm, respectively The fact that the Cd content of agricultural area was lower than that of green area is remarkable.

The Effect of n-Alkanols on the Lateral Diffusion of Synaptosomal Plasma Membrane Vesicles Isolated from Bovine Cerebral Cortex

정인교,강정숙,윤일,Chung, In-Kyo,Kang, Jung-Sook,Yun, Il The Korean Society of Pharmacology 1993 대한약리학잡지 Vol.29 No.1

Intramolecular excimer formation with the fluorescent probe 1,3-di(1-pyrenyl)propane (Py-3-Py) was used to investigate the effects of methanol, ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, 1-heptanol, 1-octanol, 1-nonanol and 1-decanol on the lateral diffusion of synaptosomal plasma membrane vesicles isolated from bovine cerebral cortex (SPMV). The n-alkanols increased the excimer to monomer fluorescence intensity ratio (I'/I) of Py-3-Py in the SPMV. In a dose-dependent manner, n-alkanols increased lateral diffusion of hydrocarbon region of bulk (inner+outer monolayers) SPMV lipid bilayers, and the potencies of n-alkanols up to l-nonanol increased with carbon chain length. It appears that the potencies in bilayer fluidization due to the lateral diffusion increase by 1 order of magnitude as the carbon chain length increases by two carbon atoms. The cut-off phenomenon was reached at 1-decanol, where further increase in hydrocarbon length resulted in a decrease in pharmacological activity. n-Alkanols의 분자적 약리작용기전 탐구에 기초자료를 제공하기 위하여 소의 신선한 대뇌피질로부터 분리한 synaptosomal plasma membrane vesicles (SPMV) 지질 이중층의 측방확산운동에 미치는 n-alkanols의 영향을 형광 probe법으로 검색하였다. n-Alkanols는 SPMV 지질 이중층의 측방확산운동 범위와 속도를 농도 의존적으로 증가시켰고 1-nonanol까지는 탄소수가 두개 증가될 때마다 그 효력은 약 10배 가량 증가되었으나 탄소수 10개인 1-decanol의 효력은 오히려 감소되는 경향을 나타내었다.

구강 편평상피세포암의 처치와 예후에 관한 임상적 연구

정인교(ln Kyo Chung),김태규(Tae Gyu Kim),김종렬(Jong Ryeol Kim),양동규(Dong Gyu Yang),신상훈(Sang Hun Shin),정기돈(Gi Don Chung) 대한구강악안면외과학회 1996 대한구강악안면외과학회지 Vol.22 No.2

This study is aimed to improve the treatment, early diagnosis, prevention and prediction in propgnosis of oral and maxillofacial malignant tumors. The authors investigated about clinincal and histopathologic findings, treatments in 52 cases and survival rate of 23 cases to have been diagnosed and treated in the Department of Oral and Maxillofacial Surgery, College or Dentistry, Pusan National University from the 1st of January, 1986 to the 31th of September, 1993. The results were as follows: 1. Oral and maxillofacial malignant tumors occurred the most between 60~69 years of age and more often in males than females with a ratio 2.5 : 1.71% of patients were visited 3 months after onset of initial symptom and the tumors occurred the most in Stage Ⅳ with 51.9% as 27cases. 2. Surgical therapy was used the most as single therapy. Combined therapy for malignant tumor was executed more than single therapy in Stage Ⅲ, Ⅳ advanced tumor. Surgical and radiation was combined most frequently. 3. Regional neck dissection was operated most frequently for cervical neck nodes. 4. Overall 5 year survival rate of the patients possible to be investigated was 26% and overall 3 year survival rate was 43.5%. 5. The authors considered that higher stage of tumor, existence of combined disease, male than female coued be predicted poor prognosis but not in cell differentiation and age.

무한정 확장가능성과 양화

정인교 ( In Kyo Chung ) 고려대학교 철학연구소 2009 철학연구 Vol.0 No.38

이 글에서는 수학의 기초적인 영역들은 무한정 확장가능하며, 무한정 확장가능한 영역에 대한 양화문장들은 고전적이 아니라 직관주의적으로 이해되어야 한다는 논거에 의거한 덤밋의 고전 수학에 대한 비판과 직관주의 수학에 관한 옹호논변을 재구성하여 설명하고 평가하고자 한다. 우선 덤밋의 논지를 필자가 판단하기에 가장 효과적인 형태로 제시한 후, 덤밋의 논변에 대한 몇 가지 해석들이 부적절한 이유를 드러낼 것이다. 덤밋의 논변이 그의 양화사에 관한 해석 및 논리주의적 논제에 의존한다는 점을 드러낸 후, 덤밋의 논점을 개념 파악에 대한 설명의 요구로 간주함으로써, 그의 논증이 논점을 선취하는 순환적 논증이라는 비판을 벗어날 수 있음을 보일 것이다. 이렇게 재구성된 덤밋의 논증은 반박하기 힘든 강력한 논증이라는 평가를 내릴 수 있다. Michael Dummett argued that fundamental domains of mathematics are indefinitely extensible and that quantification over indefinitely extensible domains should be intuitionistic, not classical. Based on these arguments, he criticized classical mathematics and defended intuitionistic mathematics. I give a reconstruction and an evaluation of Dummett`s argument. First, I give what I think is a most effective form of Dummett`s argument and criticize some interpretations of `indefinite extensibility` as inadequate. Then it is pointed out that Dummett`s argument depends on an interpretation of quantifiers and a logicist thesis. An objection that Dummett`s requirement concerning classical quantification begs the question against the realist is examined. It is argued that the real point of Dummett`s requirement is the requirement for a non-circular explanation of the realist conception of quantification. It is argued that, under this interpretation, Dummett`s argument is not circular but very effective.

Reviews : Yiannis N. Moschovakis , Notes on Set Theory , Undergraduate Texts in Mathematics , Springer - Verlag , New York , Berlin , etc. , 1994 , xiv + 272 쪽

정인교(In Kyo Chung) 한국논리학회 1997 論理硏究 Vol.1 No.1

논문 : 직관주의적 유형론에서의 명제와 판단

정인교 ( In Kyo Chung ) 한국논리학회 2011 論理硏究 Vol.14 No.2

마틴뢰프의 직관주의적 유형론의 중요 사항들을 설명하고, 그 체계의 가장 중요한 특성 중의 하나인 명제와 판단의 구분에 관해 검토한다. 1절에서 문제를 도입한 후, 2절에서 직관주의적 유형론의 명제개념은 직관주의적 명제개념의 발전된 형태임을 보이고, 3절에서는 직관주의적 유형론에서 가장 기본적인 판단개념을 설명한 후, 4절에서 직관주의적 유형론의 기본적인 추론규칙들을 설명하고 그 적용의 한 사례를 검토할 것이다. 마지막으로 5절에서, 직관주의적 유형론에서 명제와 판단의 구분이 차지하는 중요성을 부연한 후, 기초론적 체계에서 명제와 판단의 구분이 필수적인지의 문제와 관련하여, 통상적인 프레게적 구분으로부터 시작하여 직관주의적 유형론에서와 같은 구분에 이르기 위해서는 어떤 것들이 전제되거나 정당화되어야 하는지 검토할 것이다. We explain some basic elements of Martin-Lof`s type theory and examine the distinction between propositions and judgments. In section 1, we introduce the problem. In section 2, we explain the concept of proposition in the intuitionistic type theory as a development of the intuitionistic conception of proposition. In section 3, we explain the concept of judgment in the intuitionistic type theory. In section 4, we explain some basic inference rules and examine a particular derivation in the theory. In section 5, we examine one route from the Fregean distinction between propositions and judgments to the distinction between them in the intuitionistic type theory, paying attention to the alleged necessity for introducing different forms of judgments.

직관주의적 유형론에서의 분석성과 완전성

정인교 ( In Kyo Chung ) 한국논리학회 2011 論理硏究 Vol.14 No.3

마틴뢰프는 그의 직관주의적 유형론에서의 판단형식들에 관한 분석 에 의거하여, 통상적인 논리법칙들과 수학의 흥미로운 판단들은 분석판단이 아닌 종합판단에 해당하며, 분석판단의 논리는 결정가능하고 완전하지만 종합판 단의 논리는 결정가능하지 않으며 불완전하다고 주장한다. 이 글의 목적은 마 틴뢰프의 논지를 보다 분명히 하여 검토하려는 것이다. 1절에서 필자가 이해한 단형 유형론의 기본 사항들을 검토한 후, 2절에서는 마틴뢰프의 분석/종합 구 분을 보다 분명히 드러내고, 마틴뢰프의 구분에 대한 가능한 비판 및 ``통상적 인 논리법칙들과 수학의 흥미로운 판단들은 종합판단에 해당한다``는 논제를 검 토한다. 3절에서는 ``분석판단의 논리는 결정가능하고 완전하지만 종합판단의 논리는 결정가능하지 않으며 불완전하다``는 논제를 보다 분명히 드러내어 검토 한다. Based on his analysis of judgement forms in intuitionistic type theory, Martin-Lof claims that the usual logical laws and interesting mathematical judgements are synthetic, not analytic. He further claims that the logic of analytic judgements is decidable and complete, while the logic of synthetic judgements is undecidable and incomplete. The aim of this article is to clarify and examine his claims. In section 1, I explain and give some comments on the monomorphic version of intuitionistic type theory. In section 2, after clarifying Martin-Lof`s distinction between analytic and synthetic judgements, I examine some possible objections to it and evaluate the thesis that the usual logical laws and interesting mathematical judgements are synthetic. In section 3, I clarify and examine the thesis that the logic of analytic judgements is decidable and complete, while the logic of synthetic judgements is undecidable and incomplete.

직관주의적 유형론에서의 진리개념

정인교 ( In Kyo Chung ) 한국논리학회 2013 論理硏究 Vol.16 No.3

이 글의 목표는 직관주의적 유형론에서의 진리개념이 어떻게 이해될 수 있는지를 검토하고, 이에 의거하여 직관주의적이면서 객관적인 진리개념을 확보하는 문제에 있어서 프라위츠의 논증보다 진전된 논증을 제시하는 것이다. 이를 위해, 직관주의적 유형론에서의 명제, 유형 및 판단의 구분을 프레게의 판단이론과 비교하며 간략히 설명한 후, 직관주의적 유형론에서의 진리판단을 분석하고, 이에 의거해 증명의 존재의 확정성이 어떻게 이해될 수 있는지 밝힐 것이다. 또한 직관주의적 유형론에서 진리판단으로서의 존재판단이 어떻게 이해되어야 하는지, 특히 왜 그것이 존재양화명제가 될 수 없는지 그 이유를 밝히고, 존재판단을 생략적 판단으로 해석하는 한 견해를 비판할 것이다. 직관주의적 유형론에서의 진리개념에 관한 이 글에서의 분석은 증명의 존재의 확정성 문제와 증명의 존재의 비명제적 성격을 분명히 한 점에서 직관주의적이고 객관적인 진리개념에 대한 프라위츠의 규정보다 진전된 형태의 설명임을 밝히고, 이런 진리개념에 대한 주관적 진리개념의 옹호자들의 한 비판에 답할 것이다. I examine the notion of truth in the intuitionistic type theory and provide a better explanation of the objective intuitionistic conception of mathematical truth than that of Dag Prawitz. After a brief explanation of the distinction among proposition, type and judgement in comparison with Frege`s theory of judgement, I examine the judgements of the form ``A true`` in the intuitionistic type theory and explain how the determinacy of the existence of proofs can be understood intuitionistically. I also examine how the existential judgements of the form ``Pf(A) exists`` should be understood. In particular, I diagnose the reason why such existential judgements do not have propositional contents. I criticize an understanding of the existential judgements as elliptical judgements. I argue that, at least in two respects, the notion of truth explained in this paper is a more advanced version of the objective intuitionistic conception of mathematical truth than that provided by Prawitz. I briefly consider a subjectivist`s objection to the conception of truth explained in this paper and provide an answer to it.

서평 : 『집합론 입문』(최창선 지음, 경문사, 2005, 7+286쪽)

정인교 ( In Kyo Chung ) 한국논리학회 2006 論理硏究 Vol.9 No.1