유기농 콩 추출물의 항염증 및 항알레르기 효과

정은경,서은혜,박준호,심혜림,김경희,이병용,Chung, Eun-Kyung,Seo, Eun-Hye,Park, Jun-Ho,Shim, Hye-Rim,Kim, Kyung-Hee,Lee, Byung-Ryong 한국유기농업학회 2011 韓國有機農業學會誌 Vol.19 No.2

유기농재배 콩을 다양한 용매에서 추출하여 그 추출물에 대한 항산화 효과, 항염증 효과, 대식세포의 세포사멸 보호 효과, 그리고 알레르기 저해효과를 비교하였다. DPPH 법과 SOD 효소의 활성 측정으로 항산화 능력을 평가하였으며, 항염증 효과는 LPS로 유도시킨 Raw 264.7 세포주에서 염증 매개 단백질인 Cox-2와 iNOS의 발현량을 Western blotting으로 조사하여 분석하였다. 또한 대식세포 보호 효과를 세포사멸 조절 단백질인 Bcl-xl의 발현량조사로 평가하였고, 1mM $H_2O_2$ 처리로 유도되는 세포사멸의 보호효과를 세포 수 측정법으로 조사하였다. 항알레르기 효과는 흰쥐의 비만세포인 RBL-2H3 세포주를 사용하여 IgE로 매개되는 비만세포의 탈과립화를 OPT assay로 측정하여 분석하였다. 그 결과, 유기 재배 콩의 다양한 추출물에서 항산화, 세포사멸 보호, 항염증 효과를 나타내었다. 특히 유기농 콩의 열수 추출물은 LPS로 유도시킨 염증반응을 효과적으로 억제하는 것으로 나타났다. 그러나 항알레르기 효과는 모든 추출물에서 히스타민 유리량이 약간 감소하는 것으로 나타나 유기농 콩의 특별한 효과를 확인할 수 없었다. 콩에는 많은 유용한 생리활성물질 뿐 만 아니라 알레르기 유발 물질도 존재하는 것으로 알려져 있지만 조추출물 상태에서는 특이적인 알레르기 유발보다 오히려 항알레르기 효과가 나타났다. 결론적으로, 만성 염증 및 천식, 그리고 아토피피부염과 같은 염증관련 질환에는 유기 재배된 콩이 좋은 억제 효과를 가지고 있다고 판단된다. This study was carried out to investigate the biological effects of organic soybean extracts. Cellular and molecular analysis was performed to determine anti-oxidative, anti-inflammatory, anti-apoptotic, and anti-inflammatory effects of soybean extracts. First, we obtained various solvent extracts of soybean such as water, ethanol, and methanol. Molecular and cellular analysis were performed with 0.1 mg/ml concentration of each solvent extracts. The results of anti-oxidative, antiinflammatory and anti-apoptotic effects of organic soybean extracts were prominent. However, organic soybean extracts were not observed in anti-allergic effects determined by releasing histamine from rat mast cell line, RBL-2H3. Conclusively, organic soybean suppress inflammatory responses. In addition, organic soybean could be applied as a functional food ingredient for treatment of chronic inflammation, asthma, and atopic dermatitis with enhanced anti-inflammatory activities.

의과대학 학생의 소진에 대한 지도사례 분석

정은경,최기오,한의령,Chung, Eun-Kyung,Chay, Kee-Oh,Han, Eui-Ryoung 연세대학교 의과대학 2014 의학교육논단 Vol.16 No.2

Medical students often need high levels of specialized institutional and personal support to recover from a burnout experience and to prevent student failure. This study aimed to present approaches to supporting medical students who had experienced burnout using case studies. The study subjects were 45 burnout cases who had been supported by the student support system and committee in one medical school. The factors associated with burnout include poor social network: the lack of belongingness, immature sense of identity, poor mental health, a lack of intrinsic motivation and aptitude, or a major personal crisis. We summarized some tips according to the factors associated with burnout. These tips should provide guidance to organizations and individual support providers to encourage the best quality support for medical students with burnout experiences.

노인에서 치매 조기선별을 위한 시각.금전계산 검사의 유용성

정은경,신민호,이정애,Chung, Eun-Kyung,Shin, Min-Ho,Rhee, Jung-Ae 대한예방의학회 2003 Journal of Preventive Medicine and Public Health Vol.36 No.2

Objectives : Dementia has emerged as a leading public health problem in elderly persons, and its early detection is important for the treatment of curable cases, and in the educational support for other family members. Although dementia screening tests are available, they have not gained widespread use in community or primary care settings. Our goal was to validate the Tine and Change (T&C) Test, -including its validity and reliability in patients, and to assess it as a simple, standardized method for the screening of dementia in the rural elderly. Methods : The participants in this study comprised of 59 patients from an urban hospital and 405 persons from a rural community aged 65 years or older. The time test evaluated the understanding of clock hands indicating 11:10, and the change test the ability to make 1,000 Won from a group of coins, consisting of one 500, seven 100, and seven 50 Won coins. The T&C ratings were validated against a reference standard based on the physician's diagnosis of the patients. The convergent validity in relation to other cognitive measure, test-retest agreement, and inter-observer reliability were assessed. To assess the relationship between the Korean Mini-Mental State Exam (K-MMSE) and the T&C Test, the mean K-MMSE scores were compared with the results of the T&C Test in the elderly from a rural community. Results The T&C Test had a sensitivity and specificity of 73.0, and 90.9%, and positive and negative predictive values of 93.1, and 66.7%, respectively. The test-retest and inter-observer agreement rates were both 95%. The K-MMSE scores and T&C Test were significantly related in the elderly from a rural community (p<0.01), The T&C Test was not influenced by the educational status. The Time and Change Tests took a mean of 6.3 and 12.7 seconds, respectively, to complete Conclusion : The T&C Test is a simple, accurate and reliable, performance-based tool in the screening for dementia. Because it is quick, and easy-to-use, it is hoped the T&C Test will be used for the widespread cognitive screening of aging populations.

외국 의과대학에서의 진로탐색 및 진로지도 프로그램

정은경,Chung, Eun-Kyung 연세대학교 의과대학 2013 의학교육논단 Vol.15 No.2

Medical students can choose to pursue any of a large number of specialties. This diversity reflects exciting opportunities, yet it also present significant challenges, such as providing medical students with adequate resources and guidance to help them to make informed career decisions. Additionally, because the medical internship will be abolished in the near future, many Korean medical schools have recently focused on implementing a career planning and advising program. This paper describes the Careers in Medicine (CiM) program offered by the Association of American Medical Colleges as a framework for other schools to adopt or adapt as they consider the best ways to address the career counseling needs of their own students. CiM is a comprehensive career planning program that provides students with the skills, information, and resources to choose a specialty and residency program that meets their career goals. CiM follows a four-year, four-step career planning process including self-understanding, exploring a variety of medical careers, and finally choosing a specialty. The CiM program has been evaluated as successful because of widespread participation and positive feedback from medical students. The information in this study can be used to develop a formal career advising program throughout the four years of medical school.

이용자 반응 기반 이미지 감정 접근점 확장에 관한 연구

정은경,Chung, Eun Kyung 한국비블리아학회 2014 한국비블리아학회지 Vol.25 No.3

컴퓨터 정보기술의 발전과 함께 감정 기반 컴퓨팅이 다양한 분야에 빠르게 발전하여 확산되고 있다. 감정 기반 컴퓨팅의 지속적인 발전을 위해서는 이미지와 같은 멀티미디어의 콘텐츠의 감정 기반 색인과 검색이 필수적이다. 그러나 감정과 같은 추상적 개념은 주관적이며 이미지의 하위 수준 속성에서 유추하는데 한계가 있기 때문에 감정 색인은 통상적으로 난제로 여겨진다. 본 연구는 감정 색인 개선을 위해서 이미지에 대하여 이용자가 느끼는 감정 반응을 활용하여 이미지를 감정으로 접근하는데 있어서 확장된 접근점을 제공하는 방안을 고찰하였다. 이를 위하여 유로피아나 DB에서 사랑, 행복, 분노, 공포, 슬픔의 5가지 기본 감정을 표현한 이미지 15건을 선정하여 20명의 연구 참여자에게 보여주고 용어를 수집하였다. 이용자의 이미지 반응에서 수집한 용어는 정련 후 총 399건의 고유한 용어로 나타났다. 고유한 399건의 용어는 전체 1,093회 출현하였으며, 동시출현단어분석을 수행하여 상위 출현한 용어 네트워크를 구현하였다. 동시출현단어분석 기반의 네트워크를 통해서 기본 감정 용어와 함께 빈번하게 출현하는 용어를 규명하였다. 이를 통해 기본 감정용어와 함께 확장되어 제시될 수 있는 용어는 형용사, 동작/행위 표현 등 다양하게 나타났다. Given the context of rapid developing ubiquitous computing environment, it is imperative for users to search and use images based on affective meanings. However, it has been difficult to index affective meanings of image since emotions of image are substantially subjective and highly abstract. In addition, utilizing low level features of image for indexing affective meanings of image has been limited for high level concepts of image. To facilitate the access points of affective meanings of image, this study aims to utilize user-provided responses of images. For a data set, emotional words are collected and cleaned from twenty participants with a set of fifteen images, three images for each of basic emotions, love, sad, fear, anger, and happy. A total of 399 unique emotion words are revealed and 1,093 times appeared in this data set. Through co-word analysis and network analysis of emotional words from users' responses, this study demonstrates expanded word sets for five basic emotions. The expanded word sets are characterized with adjective expression and action/behavior expression.

전남대학교 의과대학 의예과 교육과정 개발과 편성사례

정은경,Chung, Eun-Kyung 연세대학교 의과대학 2017 의학교육논단 Vol.19 No.3

The educational goal of premedical education is to provide the desired college-level training in liberal arts as well as sciences, and to equip students with a basis for future medical studies. The purpose of this study was to introduce a premedical curriculum at Chonnam National University Medical School and to provide baseline data for developing an improved premedical curriculum. The reformed premedical curriculum has been followed since 2017. Formal premedical curriculum consists of basic education and character education through liberal arts study and major courses related to medical education. In addition to the formal premedical curriculum, students are supported through various programs that help develop interpersonal and intrapersonal competences.

하이브리드 방식에 의한 경제.인문.사회 분야 표준분류체계 개선에 관한 연구

정은경,박지연,Chung, Eun-Kyung,Park, Ji-Yeon 한국비블리아학회 2009 한국비블리아학회지 Vol.20 No.3

The ultimate goal of classification systems is to provide tools for information management and services through collocation of information objects in similar topics. The National Research Council for Economics, Humanities, and Social Sciences(NRCS) aims to organize the research products from 23 research institutes. To manage and organize the research products effectively, the standard classification system has been developed in conjunction of users' survey and the Business Reference Model(BRM). Although the standard classification system consists of users' perspectives and the aspects of organizational functions, there are limits to apply the system into classification practices. In this study, the proposed hybrid approach is to combine a clustering approach with 1,884 keywords from the titles of research products between 2007 and 2008. The clustering approach is performed in a heuristic way according to the KDC due to the lack of digital full texts of research products. The results of this study proposed a revised standard classification system for NRCS with 16 headings and 90 sub-headings. The revised standard classification system will play an important role in managing research products effectively.

의과대학의 학생 지원

정은경,Chung, Eun-Kyung 연세대학교 의과대학 2022 의학교육논단 Vol.24 No.3

배추 무름병에 대한 저항성 평가를 위한 접종 방법 확립 및 배추 품종 간 무름병 감수성 비교

정은경(Eun Kyung Chung),용영록(Young Rog Yeoung),장현철(Xuan Zhe Zhang),최보라(Bo Ra Choi),김병섭(Byung Sup Kim) 한국원예학회 2002 한국원예학회 학술발표요지 Vol.2002 No.3

생후 36개월 미만아 자녀를 둔 부모의 부모되기 경험의 의미

정은경 ( Eun Kyung Chung ) 미래유아교육학회 2009 미래유아교육학회지 Vol.16 No.3

본 연구는 생후 36개월 미만아를 둔 부모가 자녀 양육과정에서 어떠한 경험을 하고 있으며 이 시기의 부모되기 경험의 의미는 무엇인가를 알아보고자 하여, 생후 33개월아와 생후 6개월아 두 자녀를 둔 부모를 총 9회 심층 면담하여 자료 분석하였다. 그 결과 이 시기의 부모되기 경험은 태아에 대한 적극적인 관심과 반응을 보였으며, 부모의 생활 패턴이 달라졌고, 자녀양육에 타인의 도움이 절실한 시기였다. 또한 부모들끼리 서로 자극을 주고 받으면서 정보를 공유하고 있었고, 이 시기는 부모로써 경제적 자립을 시작한 시기로 자녀 양육을 위한 물질문화에 대한 선망이 있었다. 나아가 영·유아기의 가장 중요한 활동인 놀이를 놀이 공원 등을 방문하는 것으로 일시적으로 질적으로 제공했다고 여겼다. 자녀 양육을 위한 부부역할은 모성 위주의 양육 문화로 인해 불균등이 있기는 하지만 과거보다 많이 발전하였다. 부모됨의 지도자인 할머니 할아버지의 손자녀에 대한 양육태도도 많이 변화되었다. This study was designed to see what kind of experience of parents with less than 36-month-old children go through in raising children and what is the meaning of becoming parenthood. For this purpose, data were collected by conducting total 9 in-depth interviews with parents who had a 33-month-old kid and a 6-month-old one. The data indicated that parent with 36-month-old infants showed great interest and keen responsiveness toward fetus, that their lifestyle became different, and that they were in desperate need of assistance from others. In addition, they were willing to share information with other parents and exchange stimuli, and were anxious to obtain financial resources required to nurture their kids when they were at the initial stage of economic independence. Parents who had a 36-month-old children thought they provided quality fun to their kids by taking them to amusement parks at the time when playing is the most important pleasure kids can have. Still, owing to the cultural background which dictates that mothers had main responsibility of bringing up kids, mothers suffered parental inequality, but things were improving compared with the past practices. Grandparents, who act as guide for parenthood, were going through great changes in their attitudes about nurturing their grandchildren.