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이은정 ( Eun Jung Lee ),김현진 ( Hyun Jin Kim ),정경아 ( Kyoung Ah Jung ),임병렬 ( Ryong Ryol Lim ),김태효 ( Tae Hyo Kim ),이옥재 ( Ok Jae Lee ),주영태 ( Young Tae Joo ) 대한내과학회 2007 대한내과학회지 Vol.72 No.2
위장관내 이물은 대부분 자연적으로 배출되지만 길고 날카로우며 단단한 금속성 물질은 다양한 합병증을 유발한다. 따라서 신속하게 내시경으로 제거를 하는 것이 최선이다. 그러나 초기에 이물 제거에 실패하면 복부 방사선 검사로 주의깊게 경과관찰을 해야 한다. 이물이 우하복부에 고정되어 변화가 없으면 대장내시경을 이용하여 제거를 시도해야 하며 이러한 방법에도 실패하면 복강경을 이용한 수술 제거가 시행되어야 한다. 저자들은 치과 치료 중 우연히 치근관 파일을 삼켜 내원한 환자에서 이물이 충수 돌기에 저류된 것을 확인하고 합병증이 발생하기 전에 복강경을 통한 충수 돌기 제거술로 이물을 제거한 예를 경험하였기에 문헌고찰과 함께 보고한다. Once ingested foreign bodies pass through the stomach, 80 to 90 percent of them will exit via the gastrointestinal tract and they are excreted naturally in 7-10 days; surgical treatment is not required in most case. But once foreign bodies permeate the appendix, it is difficult for them to be excreted again to the cecum; therefore, this can possibly cause appendicitis or perforation. Especially in case of long, pointed, thin, stiff, sharp and/or metalic objects, the risk of perforation will increase. We attempted to remove an endodontic file in the appendix by colonoscopy. This was done in a patient who came to hospital because he swallowed an endodontic file during endodontic therapy. But we failed to retrieve it, and so we got rid of the foreign body by performing elective surgery before the occurrence of complications. We report here on surgical removal of an apppendiceal foreign body along with a review of the literature. (Korean J Med 72:209-212, 2007)
과민성(過敏性) 대장증후군(大腸症候群)에 대한 문헌적(文獻的) 고찰(考察)
조윤성,정종안,홍광해,정경아,Cho, Yoon-Sung,Jung, Jong-An,Hong, Gwang-Hae,Jeong, Kyoung-Ah 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.2
Objective & Methods : Irritable Bowel Syndrome is occurred frequently in daily life. Nevertheless. medical treatment of the Irritable Bowel Syndrome is almost dependent on western cure, but that cure is not effective enough. So we chose the oriental medicine textbook that were dealing with the oriental concept and the treatment of Irritable Bowel Syndrome. we got these results. Results were as follows : 1. Irritable Bowel Syndrome is characterised by recurrent or chronic abdominal pain, with distension, disturbed defecation and psychic problems without organic lesions. 2. The etiology of Irritable Bowel Syndrome include stress. disharmony of liver and spleen, the coldness of spleen and kidney and the lack of qi or yin, etc. 3. The oriental treatments of Irritable Bowel Syndrome are warming spleen and kidney, easing liver and stopping diarrhea. 4. The internal medication of Irritable Bowel Syndrome was the most used 11 times Tongsayobang(痛瀉要方) and 10 times Yijungtang(理中湯). 5. The most many used herb were Atractylodjs macrocephalae rhjzoma(白朮), Gjnseng Radix (人蔘), Cjnnamomj Cortex(肉桂), Polyporus(猪笭), etc.
김윤수 ( Yoon Soo Kim ),이선옥 ( Sun Ok Lee ),이영경 ( Young Kyoung Lee ),박한뫼 ( Han Moie Park ),정경아 ( Kyung Ah Jung ),전선희 ( Sun Hee Chun ),안정자 ( Jung Ja Ahn ),김종일 ( Chong Il Kim ),한운섭 ( Woon Sub Han ),김승철 ( Se 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.10
Multiple primary malignant neoplasm means that more than 2 cancers are independently developed in one individual. In general, the neoplasms are diagnosed simultaneously or within 6 month interval. Simultaneous presentation of carcinomas involving ovary an
증례 : 소화기 ; 낭액 CA 19-9 및 CEA 증가를 동반한 진성 비장낭종 1예
심기식 ( Ki Shik Shim ),김현진 ( Hyun Jin Kim ),문인규 ( In Kyu Moon ),정경아 ( Kyoung Ah Jung ),김태효 ( Tae Hyo Kim ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ) 대한내과학회 2009 대한내과학회지 Vol.76 No.3
True non-parasitic splenic cysts are rare. Series have reported over 30 cases of true splenic cysts producing elevated serum CA 19-9 levels. A 27-year-old woman presented with a painless mass in her left upper abdomen. Computed tomography (CT) of the abdomen showed a 16-cm cyst in the spleen. The serum CA 19-9 and CEA levels were 432 U/mL and 1.67 ng/mL, respectively. The cystic fluid CA 19-9 and CEA levels were markedly elevated. A splenectomy was performed. The pathology showed a benign true epidermoid cyst, which was negative for CEA. The serum CA 19-9 level returned to normal after removing the splenic cyst. This is the first reported case of a true benign splenic cyst producing high levels of CA 19-9 and CEA in Korea. (Korean J Med 76:348-351, 2009)
정영태,정경아 광주보건대학 2000 論文集 Vol.25 No.-
To investigate the defensive effect of Angelica keiskei koidz against the mercury toxicity, ICR mouse(30g) were divided into 3groups: the control group, the mercury treated group, and the Angelica keiskei koidz-mercury treated group. 1. The result of mercury treated group was as follows. The nucleus was observed irregularly. Rough endoplasmic reticulum(rER) and mitochondria were modificated. Many lysosome observed. 2. The result of Angelica keiskei koidz-mercury treated group was as follows. The mucleus was observed normally. rER showed slightly dilated. Many lysosome and modificated mitochondria were observed. 3. As result, the Angelica keiskei koidz has positive effect on reducing toxicity of mercury on the mouse liver.
상피성 난소암에서 수술 전 혈청 CA-125 농도에 의한 일차 종양축소수술의 결과 예측에 관한 연구
박한뫼,김윤수,신은경,김미경,정경아,박미혜,전선희,안정자,김종일,김승철 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.2
목적 : 상피성 난소암에서 수술 전 혈청 CA-125가 일차 종양축소수술의 결과를 예측할 수 있는지에 대해서 알아보고 최적의 민감도와 특이도를 보이는 혈청 CA-125 농도의 cutoff point를 알아보고자 하였다. 연구 방법 : 1997년 1월부터 2002년 8월까지 이대목동병원에 내원하여 상피성 난소암으로 진단받고 일차 종양축소수술을 시행받은 85명의 환자를 대상으로 후향적인 연구를 시행하였다. 모든 환자는 수술 전에 혈청 CA-125 농도를 측정하였으며 ROC법을 이용하여 종양축소수술의 결과를 예측할 수 있는 최적의 CA-125의 농도를 결정 하였다. 결과 : 모든 환자의 혈청 CA-125농도의 중앙값은 890.9 U/mL이었으며, 수술 전 혈청 CA-125는 조직형, 세포분화도, 병기, 복수 등과 통계적으로 유의한 관련이 있었다(p<0.05). 또한 수술 전 혈청 CA-125농도의 중앙값은 종양축소수술이 적절하게 시행된 환자와 그렇지 않은 환자간에 유의한 차이를 보였다(2584.8 U/mL vs. 524.8 U/mL, p<0.05). ROC법을 이용하여 수술 전 혈청 CA-125 농도가 1050 U/mL에서 종양축소수술의 결과를 가장 잘 예측할 수 있는 cutoff point임을 알 수 있었다(민감도 66.7%, 특이도 64.0%, 양성예측도 81.6%, 음성예측도 44.4%). 결론 : 본 연구에서 수술 전 혈청 CA-125농도는 종양축소수술의 결과 예측에 도움이 될 것으로 생각되나, 음성예측도가 낮아 수술 전 혈청 CA-125농도만을 이용하여 난소암 환자에서 복합 선행화학요법 대상자를 선정하는데는 한계가 있는 것으로 판단된다. 따라서 난소암 환자에서는 수술 전 여러 임상정보를 종합적으로 고려하여 복합선행화학요법이 결정되어야 할 것이다. Objective : To evaluate the ability of preoperative serum CA-125 level to predict the outcome of primary cytoreductive surgery in patients with epithelial ovarian carcinoma. Methods : We performed a retrospective chart review of 85 consecutive patients with epithelial ovarian carcinoma. All patients had preoperative serum CA-125 levels measured. We used a receiver operating characteristics curve (ROC) to determine the CA-125 level with the maximal power in predicting the outcome of primary cytoreductive surgery. Results : The median CA-125 level was 890.9 U/mL for all patients. Preoperative CA-125 level had significant correlations with histology, tumor grade, stage, and the presence of ascites (p<0.05). Also, preoperative CA-125 level showed significant difference between patients with suboptimal cytoreduction and those with optimal cytoreduction (2584.9 U/mL vs. 524.8 U/mL, p<0.05). Using the ROC, we found that preoperative CA-125 level of 1050 U/mL had the most powerful ability in predicting the outcome of primary cytoreductive surgery, but a poor negative predictive value (sensitivity 66.7%, specificity 64.0%, PPV 81.6%, NPV 44.4%). Optimal cytoreductive surgery was achieved in 81.6% (40/49) among patients with CA-125 <1050 U/mL, but 55.6% (20/36) among those with CA-125=1050 U/mL (p<0.05). Conclusion : We think that preoperative CA-125 level may be used for selection of candidates for neoadjuvant chemotherapy before primary cytoreductive surgery. But preoperative CA-125 level was a weak negative predictor of primary optimal cytoreductive surgery. Thus, preoperative CA-125 level could not be a primary predictor of the outcome of primary cytoreductive surgery and should be considered in the context of other preoperative features.