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임상연구 : 제왕절개술과 전자궁적출술 환자에서 정맥자가통증조절을 이용한 수술 후 통증조절
전연수 ( Yeon Soo Jeon ),김용신 ( Yong Shin Kim ),주진덕 ( Jin Deok Joo ),인장혁 ( Jang Hyeok In ),최진우 ( Jin Woo Choi ),강유진 ( Eu Jin Kang ),김대우 ( Dae Woo Kim ),임용걸 ( Yong Gul Kim ),이정아 ( Jung Ah Lee ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.52 No.2
Background: Postoperative pain degree is variable according to the site, type, and method of operation. This study compared the pain degree and amount of analgesics required among 3 types of operation. Methods: Ninety patients were selected that cesarean section (Group I, n = 30), open total hysterectomy (Group II, n = 30), laparoscopic total hysterectomy (Group III, n = 30) were scheduled. Patients received PCA with basal rate 2 ml/h, bolus 1 ml, lockout interval 5 min using fentanyl and ketorolac. We evaluated VAS at 30 min, 2, 6, 12, 18, 24, 36, 48 h postoperatively, demand of button and attempt of button, 6 hourly used amount of analgesics; side effects and degree of satisfaction after 24, 48 h postoperatively. Results: The rest VAS decreased below 30 at 6 hr in group I & II and at 2 hr in group III. More analgesics were needed for the first 6 hr compared with remained time in 3 groups (group I vs. group II vs. group III, P < 0.05). Total amount of analgesics including loading dose were fentanyl 1,536 ± 342μg, ketorolac 167 ± 34 mg for group I; 1,212 ± 215μg, 132 ± 30 mg for group II; 866 ± 125μg, 97 ± 27 mg for group III (group I vs. group II vs. group III, P < 0.05). Conclusions: The postoperative pain was painful as order of cesarean section, open total hysterectomy, and laparoscopic total hysterectomy. The pain was reduced 6 hr in laparotomy and 2 h in laparoscopy. (Korean J Anesthesiol 2007; 52: 166~71)
고주파 특성과 스마트폰을 활용한 화재 대피 안내시스템 개발
전유진,전연수,염춘호,Jeon, Yu-Jin,Jun, Yeon-Soo,Yeom, Chunho 한국정보통신학회 2020 한국정보통신학회논문지 Vol.24 No.10
화재 대피시스템에 관한 연구가 증가하고 있지만, 실내공간에서 대피자의 위치 인식에 관한 연구는 부족한 실정이다. 최신 연구에 따르면 실내에서 대피자 위치 파악에 고주파 활용이 효과적일 수 있음을 제시한 바가 있다. 이에 따라 본 논문에서는 고주파 특성과 스마트폰을 활용한 대피자 위치 인식 기술 및 화재 대피 안내시스템을 개발하고자 한다. 전체 시스템은 앱 서버, 위치 인식부, 대피경로 탐색 및 출력부, Wi-Fi통신 기반의 스피커 출력부를 포함해 개발했으며, 화재 상황 데이터를 기반으로 실험을 수행하여 시스템의 실효성에 대한 가능성을 입증하였다. 본 연구는 화재 시 고주파를 활용한 대피자 위치 감별을 사용하는 화재 대피 안내시스템의 기초연구로 활용될 수 있을 것이라 기대된다. Although studies on fire evacuation systems are increasing, studies on the evacuation of evacuees in indoor spaces are insufficient. According to the latest research, it has been suggested that the use of high frequency might be effective for identifying the location of evacuees indoors. Accordingly, in this paper, the authors intend to develop evacuation location recognition technology and fire evacuation guidance system using high-frequency and a smartphone. The entire system was developed, including an app server, evacuees location recognition unit, an evacuation route search, an output unit, and a speaker unit based on Wi-Fi communication. The experimental results proved the possibility of the effectiveness of the system in the fire situation data. It is expected that this study could be used as an essential study of a fire evacuation guidance system using high frequency data in case of fire.
진동이 제동력 감소에 미치는 영향에 대한 고찰 (Braking force to reduce the vibration impact study)
권진(Jin Kwon),구본민(Bon Min Kou),전연수(Yeon Soo Jeon) 한국철도학회 2011 한국철도학회 학술발표대회논문집 Vol.2011 No.5
최근 들어 철도차량의 신뢰성에 대한 관심이 높아지고 있으며, 신뢰성에 대한 연구가 활발히 진행되고 있다. 하지만 기존에 운영중인 철도차량의 경우 명확한 진동에 대한 기준이 없이 제작 운영되고 있는 것이 사실이다. 이에 진동과 제동 작용장치의 영향을 살펴보았다. In recent years, the concern about the reliability of railway vehicles is increasing, Many studies on reliability is in progress. But, the existing railway cars have been running without any specific criteria for vibration. So, we looked into the effect of the vibration and braking devices.
신경병증성 통증모델 쥐에서 리도케인의 ERK 1/2와 CREB 단백질 억제효과
주진덕 ( Jin Deok Joo ),인장혁 ( Jang Hyeok In ),정홍수 ( Hong Soo Jung ),김용신 ( Yong Shin Kim ),김대우 ( Dae Woo Kim ),최우영 ( Woo Young Choi ),신은영 ( Eun Young Shin ),전연수 ( Yeon Soo Jeon ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.3
Background: In addition to causing the loss of voluntary sensory and motor function, spinal cord injury (SCI) often creates a state of central neuropathic pain. Rats given SCI display increases in the activated form of transcription factors ERK 1/2, p38 MAPK, and CREB in the spinal cord, which correspond to allodynia in a model of neuropathic pain. The current study was designed to determine if lidocaine had an effect on the development of neuropathic pain in response to SCI. Methods: Male Sprague Dawley rats were anesthetized and then received a L5-L6 spinal nerve ligation (neuropathic rats). The levels of intracellular cell-signaling protein, ERK 1/2 and CREB were then assessed by western blot analysis of samples collected from a sham operated (control) group, a neuropathic pain and normal saline (NP+NS) group, and a neuropathic pain and 5% lidocaine (NP+Lido) group. Results: The increased levels of ERK 1/2 and CREB protein that were observed in the neuropathic pain model were reduced by continuous infusion of 5% lidocaine. Conclusions: The current results suggest that lidocaine therapy may be an effective method of preventing and treating central neuropathic pain following SCI, and that these effects may occur via the reduced expression of ERK 1/2 and CREB in the intracellular cell-signaling pathway. (Korean J Anesthesiol 2009; 56: 319~24)
포텐션메타의 위치선정에 관한 고찰 (Study on positioning Potentionmeter)
권진(Jin Kwon),조태영(Tae-Young Cho),구본민(Bon Min Kou),전연수(Yeon Soo Jeon) 한국철도학회 2011 한국철도학회 학술발표대회논문집 Vol.2011 No.5
현대는 에너지 절약및 고효율의 시대입니다. 철도차량의 경우에도 예외는 아니어서 일찍부터 에너지 절약형 기기를 연구 개발중이며 또한 기존제작 운행중인 차량의 경우에도 에너지 절약을 위한 여러 가지 방법의 모색중에 있습니다 이에 차량의 운행에 있어서의 운행속도 요구치와 차량에 장착된 전동기에 공급되는 전류의 상관 관계에 대해 살펴 보았다. It is the age of high efficiency and energy conservation today. The railway is no exception, the research for the energy-saving devices of the railway systems is underway and various ways to save energy have been tried to the existing vehicles. So, we studied the correlation between the value demanded for train speed and the electric currents supplied to a motor while a train is operating.
실험연구 : 쥐에서 허혈 재관류 신장손상에 대한 반대편 신장의 허혈 선조정의 신장 보호효과
주진덕 ( Jin Deok Joo ),김대우 ( Dae Woo Kim ),강유진 ( Yoo Jin Kang ),김용신 ( Yong Shin Kim ),전연수 ( Yeon Soo Jeon ),인장혁 ( Jang Hyeok In ),최진우 ( Jin Woo Choi ),박연진 ( Yeon Jin Park ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.53 No.2
Background: Acute renal failure (ARF) results from renal ischemic reperfusion (IR) injury and is a major contributor to the morbidity and mortality encountered during the perioperative period. It was previously demonstrated that ischemic preconditioning (IPC) of the heart, brain, and kidney offered protection against IR injury. Therefore, this study examined whether or not distant IPC can also be effective against IR injury in other organs. Methods: C57BL6 mice were classified into three groups, Sham group (n = 7), IR group (n = 7) and Cross IPC IR group (n = 7). The sham group was subjected only to a right renal nephrectomy (ligation of renal pedicle with silk). The IR group was subjected to 30 min of left renal ischemia after a right nephrectomy. The cross IPC IR group was subjected to right renal IPC (two cycles of 5 min of ischemia and reperfusion) followed 15 min later by a right nephrectomy and 30 min left renal ischemia. The left kidney was harvested 24 h after surgery and the histology and blood creatinine level was analyzed. The left kidneys were isolated 15 min after right nephrectomy (sham, n = 7) and right renal IPC (cross IPC, n = 7), respectively, and analyzed by western blotting. Results: The level of the intra-cellular signaling proteins, iNOS, Akt and ERK increased significantly as a result of the right renal IPC, and the renal functions were well preserved in the cross IPC IR group compared with the IR group. Conclusions: Cross renal IPC offers protection by elevating the iNOS, Akt and ERK levels due to the distant oxygen free radicals stream against the opposite renal IR injury in mice. (Korean J Anesthesiol 2007; 53: 229~33)
Propofol-N2O-O2 마취 시 저농도 Ketamine 의 지속주입이 Bispectral Index 및 마취로부터의 회복에 미치는 영향
이성우,이동호,김동희,이승준,이병상,김대우,길호영,유홍성,이성익,전연수,원임수 대한마취과학회 2000 Korean Journal of Anesthesiology Vol.38 No.4
Background : Ketamine as an analgesic adjunct in propofol-based anesthesia has the benefit of patent analgesic action and more stable vital signs due to sympathetic stimulation. However, its impact an tl bispetral index mnd speed of recovery is still controvertial. The aim of this study was to evaluate the effects of continuous infusion of low cpncentrations of ketamine (0.1㎍/ml) on the bispectral index and speed of recovery from propofol-N_2O-O_2 anesthesia. Methods : Forty ASA I or II adult patients scheduled for elective orthopedic surgery were randomly allocated to one. of two groups according to intraoperative ketamine use. In group P, anesthesia was induced and maintained with propafol (Ct: 3-6 ㎍/ml), 67% nitrous oxide and 33% oxygen and the target concentration of propofol was kept at 4 ㎍/ml at least 20 min before the end of propofol infusion. In group P + K, the methnd of anesthesia was same as in group P, but the low concentration (0, 1 ㎍/ml) of ketamine was continuously infused until discontiion of propofo! using computer-assisted cotinuous infusion, Bispectral index, recovery time from anesthesia, current/effect concentration of drugs, vital signs before and at induction, end of drug infusion, eye opening time on verbal command, and orientation time were checked. Results: Changes in vital signs showed no differences between the groups. For bispectral index, there was no difference between groups initially, but it was higher (4―8) after the end of drug infusion in group P + K than in group P. Also, recovery from anesthesia was delayed significantly in group P + K (P $lt; 0.05). Conclusions : From these observations, we concluded that the use of low concentrations of ketamine during propofol-N_2O-O_2 anesthesia increased BIS, delayed eye opening and recovery from anesthesia without any benefit to vital sign stability. ( Korean J Anesthesiol 2000; 38 : 591-597 )