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김상현 ( Sang Hyun Kim ),김현정 ( Hyun Jung Kim ),김민희 ( Min Hee Kim ),박원도 ( Won Do Park ),한성훈 ( Seong Hoon Han ),유성인 ( Sung In Yu ),장효정 ( Hyojeong Chang ) 대한내과학회 2012 대한내과학회지 Vol.83 No.6
A 59-year-old man visited our hospital for facial edema and muscle weakness in both lower extremities. He was diagnosed with dermatomyositis (DM) about 1 year previously, and sudden development of proteinuria was noted. Renal biopsy revealed focal global and segmental glomerulosclerosis with slight mesangial expansion. Glomerulonephritis is rare in DM. According to our review of related literature, membranous nephropathy is the main type of DM, while mesangial proliferative glomerulonephritis is the most common type in polymyositis. The mechanism underlying the association between DM and glomerulonephritis remains to be elucidated. We herein report a case of DM associated with focal segmental glomerulosclerosis, which has not been reported previously. (Korean J Med 2012;83:828-831)