化膿性 口腔感染에서 嫌氣性細菌의 同定

장현중(Jang Hyun Jung),이상한(Lee Sang Han),변종수(Byun Jong-Soo) 대한구강악안면외과학회 1985 대한구강악안면외과학회지 Vol.11 No.2

In order to determine the prevalence of anaerobic bacteria associated with pyogenic oral infection, the author studied the specimens from twenty patients who visited the Department of Oral Surgery, K.N.U. Hospital during the period from Feb. 1985 to Nov. 1985. In this study, author used GLC (gas liquid chromatography) combined with conventional biochemical method and API-20A system. The result were summarized as follows; The average number of anaerobic bacteria in each specimen was 2.8. Total 56 strains of obligate anaerobes were identified These strains were as follows: Anaerobic gram positive cocci 17 strains (30.4%) Anaerobic gram negative cocci 1 strains (1.8%) Anaerobic gram positive bacilli 11 strains (19.6%) Anaerobic gram negative bacilli 27 strains (48.2%) The most frequent strain was Bacteroides spp. (35.7%) Gas liquid chromatographic (GLC) profiles of cellular fatty acids and metabolic products were useful in identifying Peptococcus spp., Peptostreptococcus spp., Eubacterium spp.

전치부 개방교합을 동반한 골격성 제3급 부정교합 환자에 대한 양측 하악지 시상분할 골절단술후 안정성에 관한 임상적 분석

김현수(Hyun-Soo Kim),권대근(Tae-Geon Kwon),이상한(Sang-Han Lee),김진수(Chin-Su Kim),강동화(Dong-Hwa Kang),장현중(Hyun-Jung Jang) 대한구강악안면외과학회 2007 대한구강악안면외과학회지 Vol.33 No.2

This study was conducted to patients visited oral maxillo-facial surgery, KNUH and the purpose of the study was to assess skeletal and dento-alveolar stability after surgical-orthodontic correction treated by skeletal Class III malocclusion patients with open bite versus non-open bite. This retrospective study was based on the examination of 40 patient, 19 males and 21 females, with a mean age 22.3 years. The patients were divided into two groups based on open bite and non-open bite skeletal Class III malocclusion patients. The cephalometric records of 40 skeletal Class III malocclusion patients (open bite: n = 18, non-open bite: n = 22) were examined at different time point, i.e. before surgery(T1), immediately after surgery(T2), one year after surgery(T3). Bilateral sagittal split ramus osteotomy was performed in 40 patients. Rigid internal fixation was standard method used in all patient. Through analysis and evaluation of the cephalometric records, we were able to achieve following results of post-surgical stability and relapse. 1. There was no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in maxillary occlusal plane angle of pre-operative stage(p>0.05). 2. Mean vertical relapses of skeletal Class III malocclusion patients with open bite were 0.02±1.43mm at B point and 0.42±1.56mm at Pogonion point. In skeletal Class III malocclusion patients with non-open bite, 0.12±1.55mm at B point and 0.08±1.57mm at Pogonion point. There was no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in vertical relapse(p>0.05). 3. Mean horizontal relapses of skeletal Class III malocclusion patients with open bite were 1.22±2.21mm at B point and 0.74±2.25mm at Pogonion point. In skeletal Class III malocclusion patients with non-open bite, 0.92±1.81mm at B point and 0.83±2.11mm at Pogonion point. There was no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in horizontal relapse(p>0.05). 4. There were no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in post-surgical mandibular stability(p>0.05). and we believe this is due to minimized mandibular condylar positional change using mandibular condylar positioning system and also rigid fixation using miniplate 5. Although there was no significant relapse tendency observed at chin points, according to the Pearson correlation analysis, the mandibular relapse was influenced by the amount of vertical and horizontal movement of mandibular set-back(p=0.05, r>0.304).

전산화단층촬영법을 이용한 하악전돌증 환자의 외과적 악교정술후 하악과두 위치 변화 검토

이호경,장현중,이상한,Lee, Ho-Kyung,Jang, Hyun-Jung,Lee, Sang-Han 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.3

본 교실에서 악교정수술을 시행한 하악전돌증 환자 37명(남자13명, 여자 24명)을 대상으로 술전, 술직후, 장기관찰기간동안의 전산화단층촬영법을 이용하여 술전 각 항목치의 평균값 그리고 하악골의 후퇴량 및 술후의 악관절 장애 여부와 하악과두의 위치변화에 따른 상관관계를 검토한 결과 다음과 같은 결과를 얻었다. 1. 두부축방향 전산화단층사진에서의 과두간 거리(MM')는 $84.42{\pm}5.30mm$ 였으며, 장축각은 우측 $12.79{\pm}4.92^{\circ}$, 좌측 $13.53{\pm}5.56^{\circ}$로 좌우 비슷하였으며, 기준선(AA')에서 과두의 외측점은 11.34mm, 내측점은 6.87m 정도 전방에 위치하였다. 관상면 전산화단층사진에서의 과두간 거리(mm')는 $83.15{\pm}4.62mm$였으며, 사축각은 우측 $76.28{\pm}4.28^{\circ}$, 좌측 $78.30{\pm}3.79^{\circ}$로 좌우 비슷하였다. 2. 하악골 후퇴량에 따른 술전, 술후 장기관찰에서의 과두 위치변화를 연구한 결과, Group I에서 하악과두의 전방내측 회전의 양상을 보였고, Group II는 RMD, RCA', LCA'가 감소하여 전내측의 회전양상만이 관찰되었으며, Group III에서는 RCA, RLD, RMD, LMD가 감소하여 우측 과두의 후방내측 회전양상을 보였다. MM' 도 감소하여 하악과두간의 거리도 좁아지는 경향을 관찰할 수 있었으며, 이 결과로 하악골의 후퇴량이 증가할수록 하악과두의 위치 변화가 많이 나타나는 것을 관찰할 수 있었다. 3. 술후에 악관절장애를 호소하는 환자 군과 증상을 호소하지 않는 환자 군과 비교시 하악과두의 위치 변화는 통계적인 유의성은 없었으나 Group A군에서는 하악과두가 전내측의 회전양상을 보였으나, Group B 군의 경우는 좌측 과두의 전방외측 회전을 보였으며, 관상면상 단층면에서 LCA'가 많은 감소 양상을 보였다. 이와는 달리 Group C군에서 우측 과두의 후방내측 회전양상을 보였고 RCA'각의 감소 양상을 보였다. 따라서, 하악골의 후퇴량이 많은 군은 과두위치보존술을 이용함에도 불구하고 술후의 과두의 위치가 후방내측 회전을 보였다. 또한 장기관찰의 경우 원래의 관절 위치로 회귀하는 경향은 있었으나 술전의 과두의 위치보다는 증가와 감소의 경향을 보였다. 수술후의 악관절장애 증상을 호소한 군에서 과두축의 변화를 관찰하였기에, 하악의 후퇴량이 많은 경우에는 더욱더 과두보존술식에 많은 주의를 하면 술후의 악관절 장애의 발생율은 감소하리라 사료된다. This study was intended to perform the influence of condyle positional change after surgical correction of skeletal Class III malocclusion after orthognathic surgery in 37 patients(male 13, female 24) using computed tomogram that were taken in centric occlusion before, immediate after, and long term after surgery and lateral cephalogram that were taken in centric occlusion before, 7 days within the period of intermaxillary fixation, at the 24 hours later removing intermaxillary fixation and long term after surgery. 1. Mean intercondylar distance was $84.42{\pm}5.30mm$ and horizontal long axis of condylar angle was $12.79{\pm}4.92^{\circ}$ on the right, $13.53{\pm}5.56^{\circ}$ on the left side. Condylar lateral poles were located about 12mm and medial poles about 7mm away from the reference line(AA') on the axial tomogram. Mean intercondylar distance was $83.15{\pm}4.62mm$ and vertical axis angle of condylar angle was $76.28{\pm}428^{\circ}$ on the right, $78.30{\pm}3.79^{\circ}$ on the left. 2. In amount of set back, We found the condylar change(T2C-T1C) which had increasing tendency in group III (amount of setback : 10-15mm). but there was no statistical significance(p>0.05). 3. There was some correlation between condylar change(T2C-T1C) and TMJ dysfunction. It seemed that postoperative condylar change had influenced postoperative TMJ dysfunction, through there was no statistical significance (p>0.05). As we have observed the change of condylar axis in the group that complained of TMJ dysfunction in cases of large amount of mandibular setback. So we consider that the more trying to conserve condylar position will decrease occurrence rate of post operational TMJ dysfunction.

악교정 수술환자의 술전후 하악운동 양상변화에 관한 임상적 연구

백상흠,장현중,이상한,김현수,차두원,Baek, Sang-Heum,Jang, Hyun-Jung,Lee, Sang-Han,Kim, Hyun-Soo,Cha, Doo-Won 대한구강악안면외과학회 2001 대한구강악안면외과학회지 Vol.27 No.3

저자는 1999년 6월부터 2000년 4월까지 경북대학교병원 구강악안면외과에서 하악골 후퇴를 위해 SSRO 혹은 LeFort I 골 절단술을 동반한 SSRO를 시행받은 환자 42명을 대상으로 술전, 술후 1개월, 술후 6개월에 각각 MKG를 이용하여 하악운동량 및 양상을 조사하고 이를 몇 가지 요소에 따라 군으로 나누어 계측치를 측정, 연구한 바 아래와 같은 결과를 얻었다. 1. 남녀 성별에 따른 두 군 사이에서, 좌측운동량의 변화 및 최대 개구속도의 변화량은 유의한 차이가 있었으며(p<0.05), 그 외의 항목은 차이가 없었다. 2. SSRO만을 시행 받거나 혹은 LeFort I을 동반하여 SSRO를 시행받을 경우, 수술방법에 따른 하악운동량의 변화는 유의성이 없었다.(p>0.05) 3. 하악골이동량에 따른 세 군에서 각 군사이의 하악운동량의 변화는 좌측 측방운동량에서는 $6{\sim}10mm$의 이동군이 가장 우수하였으며(p<0.05), 그 외의 항목은 통계적 유의성이 없었다. 4. 하악골의 개폐구 양상은 전두면 상에서 술전이 복잡편향형, 단순편향형, 복잡편위형, 단순편위형, 직선형 순이었고 술후 1개월에서는 단순편향형, 단순편위형, 복잡편위형, 직선형, 복잡편향형 순이며, 술후 6개월에서는 술전과 같은 순서였다. 또한 시상면상에서는 술전에 비일치형이, 술후 1개월에서는 일치형이 술후 6개월에서는 다시 비일치형이 우세하였다. 5. 술전 관절증의 증상유무에 따른 두 군사이의 하악운동량의 변화에는 통계적 유의성이 없었다(p>0.05). 6. 과두재위치장치를 적용한 군과 적용하지 않은 군에서, 두 군사이의 하악운동량의 변화에는 유의성이 없었다(p>0.05). 7. 술전 관절증이 있었던 환자중 술후 관절증의 완화가 나타난 경우가 63% 였으며, 과두재위치장치를 적용하지 않은 군에서 술후 관절증의 완화가 더 유의성있게 나타났다(p<0.05).를 보였으며 복합 레진은 유의차가 없었다. 상악 견치 (8%), 하악 제 1소구치 (5%) 순이었다. 10. I군에서 추정되는 낭의 발생 원인으로는 치수절단술을 받은 유치가 59.2%로 가장 많았고 이외에 심한 우식 및 치료 받지 않은 외상 병력등 기타 가능한 원인들이 있었다. 11.함치성 낭의 치료법으로는 I군의 경우 61.2%에서 조대술이 시행되었고, II군과 III군의 경우 61.1%, 80.0%에서 적출술이 시행되었다.mH I처치시 SM1과 SM2는 4조각의 절편으로 절단되어 같은 양상을 보였고, GS톤의 경우는 3조각의 절편으로 절단되었다. Kpn I, Sma I, Xho I 그리고 Pst I에는 절단되지 않았다.s subsp. salicinius와 유전자 유사치가 99.60%, 99.73%를 보여 Lactobacillus salivarius subsp. salicinius로 동정되었다. 이상의 결과를 종합하면 치아우식증이 없는 소아의 타액에서 분리된 유산균 중 과산화수소를 분비하여 인공치태 형성과 휘발성 유황화합물 생성을 억제하는 분리균주는 Lactobacillus salivarius subsp. salicinius로 동정되었다.적으로 낮은 수축률과 우수한 물성을 보였으며, 나노필러를 사용한 복합레진의 경우, 기존의 hybrid 필러를 이용한 레진에 비하여 수축응력을 감소시키지는 못하였다. 나노필러를 이용한 복합레진은 개발의 초기단계이며, 물성의 증가를 위한 연구가 필요할 것으로 사료된다.또 다른 약물인 glycyrrhetinic acid($100{\mu}M$)도 CCh 자극으로 인한 타액분비를 억제하였다. 이상의 결과로 미루어 gap junction은 흰쥐 악하선 세포로부터의 타액분비 조절에 중요한 역할을 하는데, 이는 gap junction이 세포막 $Ca^{2+}$ 통로를 조절함으로써 수용체 자극으로 유발된 The purpose of this study is to evaluate the relationship of the factors which could be influenced by orthognathic surgery especillay SSRO. We measured the amounts of the maximum opening, lateral movements, maximum velocity and pattern of mandibular path during the opening and closing of mandible at the following times ; preoperative, 1 month after operation, 6 months after operation respectively using MKG. And the results were compared according to the categorized subgroups. Following results were obtained : 1. The change of the amounts of mandibular lateral movement and maximum opening velocity were statistically different between male and female (p<0.05), but the others were not. 2. According to the method of operation, there was no difference in the change of the mandibular movements between the group of SSRO and SSRO plus LeFort I osteotomy (p>0.05). 3. According to the amounts of mandibular movement, the recovery of left lateral movement of the group of $6{\sim}10mm$ was better than the other groups (p<0.05). 4. In the frontal pattern of the opening and closing of the mandible, the complex deflected type (F5), simple deflected type (F4), complex deviated type (F3), simple deviated type (F2), straight type (F1) were obtained in order at the time of preoperative, simple deflected type, simple deviated type, complex deviated type, straight type, complex deflected type in order at the time of 1 month after surgery, and the result at the time of 6 months after surgery was the same with that of the time of preoperative. In the sagittal pattern, non-coincident type (S2) was predominant at the time of preoperative, and coincident type (S1) was predominant at the time of 1 month after surgery. After 6 months, the result was also the same with that of the preoperative in sagittal pattern. 5. There was not a statistical difference in the change of the mandibular movement between group of presence of the preoperative TMJ symptoms and non-presence group (p>0.05). 6. There was not a statistical difference in the change of the mandibular movement between repositioning device applied group and non-applied group (p>0.05). 7. Sixty three percents of the patients who had preoperative TMJ symptoms were improved after surgery and preoperative TMJ symptoms were more improved after operation in the repositioning device non-applied group statistically (p<0.05).

안모비대칭을 동반한 하악전돌증 환자에서 악교정 수술 전후 교근과 전측두근의 근전도 변화

손성일,손정희,장현중,이상한,차두원,백상흠,Son, Seong-Il,Son, Jung-Hee,Jang, Hyun-Jung,Lee, Sang-Han,Cha, Du-Won,Baek, Sang-Heum 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.3

The function of the masseter and anterior temporal muscles was assessed by electromyography in 30 patients with mandibular prognathism (20 patients with facial asymmetry and 10 patients without facial asymmetry) before orthognathic surgery and 4weeks afterwards. Electromyogram(EMG) recordings were made during resting, clenching and swallowing. We compared with right-left difference of this recording and asymmetry index before and after orthognathic surgery. The result of this study was as follows. 1. There was no significant right-left difference in muscle activities of masticatory muscles both asymmetric groups and controls and many variable change after orthognathic surgery.(P>0.05) 2. The mean electric activity of the masticatory muscles was found to have decreased during more clenching than resting, but there was no statistically significant difference because of individual difference of measuring values.(P>0.05) 3. The asymmetry index of masticatory muscles in asymmetric groups was significantly greater during clenching compared with controls.(P<0.05) In conclusion, no right-left difference of muscle activities was found in patients with facial asymmetry before orthognathic surgery and 4weeks afterwards. Not only muscular functioning but also many other factors, such as occlusion, temporomandibular joint disorder and trauma, probably affect facial asymmetry and will be analyzed in future studies. And we will need long term follow-up after orthognathic surgery.

안모 비대칭환자의 두부정중선에 대한 비부의 편위

박지화,손성일,장현중,권대근,이상한,Park, Ji-Hwa,Son, Seong-Il,Jang, Hyun-Jung,Kwon, Tae-Geon,Lee, Sang-Han 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.2

The purpose of this study was to evaluate the nasal deviation in mandibular prognathism with mandibulo-facial asymmetry. There were 40 patients whose mandibular prognathism with/without facial asymmetry were treated with orthognathic surgery from March 2002 to October 2003. The Group A(n=20) had a mandibulo-facial asymmetry over 6mm menton deviation in cephalogram PA and the Group B(n=20) had a mandibular prognathism. The preoperative frontal photograph, cephalogram PA and three dimensionalcomputed tomography(divided in hard tissuse image and soft tissue image) of two group was evaluated NDA(nasal deviation angle) and MDA(mandibular deviation angle). The NDA was statistical difference between asymmetry Group A and symmetry Group B(p<0.01), and was deviated in affected side of asymmetry. The MDA were also statistical difference between Group A and Group B(p<0.01), however the measurements of MDA between the frontal photograph, 3D-CT and cephalogram PA were similar to each others. The low correlation of NDA between frontal photograph and cephalogram PA in Group A and B demonstrate that we couldn't assess nasal deviation in cephalogram PA. It could be concluded that patients with mandibulo-facial asymmetry have a nasal deviation and clinician must remember this fact when they assess and treat patients.

악하선 부위에 발생한 신경초종의 치험례

조준현(Jun Hyun Cho),이용규Yong Gyoo Lee,장현중(Hyun Jung Jang),김진수(Chin Soo Kim),이상한(Sang Han Lee) 대한구강악안면외과학회 1997 대한구강악안면외과학회지 Vol.23 No.2

Neurilemmoma is a bemgn tumor of nerve sheath origin, apparently derived from the Schwann cells, which may arise from any myelinated nerve fiber Although it is a relatively common tumor, it is rarely seen in the oral cavity. Actually the greatest majority of oral neurilemmomas have been reported in tongue and cheek, and most of them have been in small size. The following case is reported because of the large tumor size and its unusual location in the area of submandibular gland. It seems to arise from the mylohyoid nerve of the fifth cranial nerve. A 35-year-old man came to the department of oral and maxillofacial surgery of Kyung-pook University Hospital in October, 1994, for treatment of an egg-sized mass in the left submandibular area which had been noticed 7 months before The mass was excised under general anesthesia, and the postoperative course was uneventful. The gross specimen was ovoid, measuring 38×18×15mm, and well encapsulated with thin fibrous capsule. Histopathological finding indicated neurilemmoma composed of Antoni type A and type B tissue.

구강점막 결손 재건시 유경협지방대이식술의 임상적 적용

이동수,김진수,이상한,장현중,최재갑,기우천,Lee, Dong-Soo,Kim, Chin-Soo,Lee, Sang-Han,Jang, Hyun-Jung,Choi, Jae-Kab,Ki, Woo-Cheon 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.3

Various local flaps and distant flaps including tongue flap, palatal island flap, and buccal flap as well as skin grafts have been used for the reconstruction of oral mucosal defect. In the posterior region of oral cavity and the buccal cheek area, buccal fat pad can be used as a pedicled graft. The buccal fat pad is different from other subcutaneous fat tissue and it is easily accessible. There are many advantages in pedicled buccal fat pad graft for the closure of oral mucosal defect. The procedure is easy, there is no visible scar in the donor site, it is capable of reconstruction of various contour, and it has good viability. We had used buccal fat pad as a pedicled graft for the closure of oral mucosal defect after the excision of tumor and the oroantral fistula. From the results of these cases, we concluded that the use of the buccal fat pad flaps was worth of the consideration for the reconstruction of oral mucosal defect in the regions of the buccal cheek, and posterior oral cavity.

가토의 두개골 결손부에 이식한 human DBM ($Grafton^{(R)}$)의 효과

김진욱,박인숙,이상한,김진수,장현중,권대근,김현수,Kim, Jin-Wook,Park, In-Suk,Lee, Sang-Han,Kim, Chin-Soo,Jang, Hyun-Jung,Kwon, Tae-Geon,Kim, Hyun-Soo 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.2

In oral and maxillofacial surgery, bone graft is very important procedure for functional and esthetic reconstruction. So, many researcher studied about bone graft material like autogenous bone, allograft bone and artificial bone materials. The purpose of this study is to evaluate the quantity of bone generation induced by $Grafton^{(R)}$ graft, human allogenic demineralized bone matrix. Total 24 sites of artificial bony defects prepared using trephin bur(diameter 8 mm) on parietal bone of six adult New Zealand White rabbits. Experimental group had six defect sites which grafted $Grafton^{(R)}$(0.1 cc). Active control group had nine defect sites, into which fresh autogenous bone harvested from own parietal bone was grafted and passive control group had nine defect sites without bone graft. After six weeks postoperatively, the rabbits were sacrificed. The defects and surrounding tissue were harvested and decalcified in 10% EDTA, 10% foamic-acid. Specimens were stained with H&E. New bone area percentage in whole defect area was measured by IMT(VT) image analysis program. Quantity of bone by $Grafton^{(R)}$ graft was smaller than that of autograft and larger than that of empty defects. In histologic view $Grafton^{(R)}$ graft site and autograft site showed similar healing progress but it was observed that newly formed bone in active control group was more mature. In empty defect, quantity and thickness of new bone formation was smaller than in $Grafton^{(R)}$-grafted defect. $Grafton^{(R)}$ is supposed to be a useful bone graft material instead of autogenous bone if proper maintenance for graft material stability and enough healing time were obtained.

재발성 치성각화낭의 임상 및 방사선학적 평가

조형우,최소영,김현수,권대근,장현중,이상한,김진수,Jo, Hyung-Woo,Choi, So-Young,Kim, Hyun-Soo,Kwon, Tae-Geon,Jang, Hyun-Jung,Lee, Sang-Han,Kim, Chin-Soo 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.5

Purpose: It is estimated that the odontogenic keratocyst (OKC) makes up 10% to 12% of all developmen-tal odontogenic cysts. The lesion has been of particular interest because of its specific histopathologic fea-ture, high recurrence rate, and aggressive behavior. Materials and Methods: We investigated 266 OKCs of Korean patients for the sex of patient, the age of the patient, the location of OKC, the recurrence rate related to radiographic impression. Results: The male-to-female ratio was 1.47:1, showing a slight male predilection. Odontogenic keratocysts had a peak of occurrence in the third decade of life. The mandibular angle and ascending ramus area (49.6%) is the most frequent site of OKCs in the jaws. Fourteen cases of unilocular (12%) and 5 cases of multilocular (20%) OKCs recurred. Thirteen cases of smooth (12.9%) and 6 cases of lobulated (14.6%) OKCs recurred. Seventeen cases of OKCs without perforation of cortical bone (12.5%) and 2 cases of OKCs with perforation of cortical bone (33.3%) recurred. Fifteen people of patients with single lesion (12.2%) and 4 people of patients with multiple lesions (66.7%) recurred. Conclusion: In this resul, we consider multiple odontogenic keratocysts can recur more easily. So we have to treat them more carefully and need long-time follow-ups.