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FDM 방식 3D 프린터에 대한 딥러닝 기반 물성 추정
임주현(Joo Hyeon Im),김원곤(Wongon Kim),안성훈(Sung-Hoon Ahn),윤병동(Byeng Dong Youn) 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.11
Additive manufacturing (AM) is playing a major role in Industry 4.0. AM can simplify the fabrication of complex shapes while minimizing manufacturing time and cost. However, the poor surface quality and weak mechanical properties of the output hinder the broad application of AM. In this study, we propose a deep learning-based method for estimating the mechanical property in a fused deposition modeling-type 3D printer. Acceleration signals were acquired in the process of outputting a tensile specimen through construction of a test-bed. In addition, a tensile test was performed using the specimen to collect information on mechanical properties. After that, features were extracted from the divided signals to analyze the correlation with the mechanical properties. Finally, the quality of highly correlated property was estimated through deep neural network. We confirmed that deep learning-based method is good at estimating property through mean square error loss and root mean square error.
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헬리코박터 파일로리 제균 치료가 위 이형성의 내시경 절제술 후 이시성 재발에 미치는 영향
송지현 ( Ji Hyun Song ),양선영 ( Sun Young Yang ),임주현 ( Joo Hyun Lim ),최지민 ( Ji Min Choi ),김상균 ( Sang Gyun Kim ) 대한소화기학회 2017 대한소화기학회지 Vol.70 No.1
목적: 헬리코박터 파일로리 감염은 위암 발생의 중요한 위험인자로 알려져 있다. 그러나 위암의 전구 병변인 이형성 환자에서 제균 치료가 이시성 종양의 발생을 줄일 수 있는지에 대해서는 아직 연구가 부족한 실정이다. 이에 본 연구에서는 위 이형성의 내시경 절제술 후 이시성 재발에 영향을 주는 위험인자들을 알아보고, 헬리코박터 파일로리 제균 치료의 효과를 장기간의 추적 검사 자료를 통해 분석해 보고자 하였다. 대상 및 방법: 2005년부터 2011년까지 위 이형성으로 내시경절제술을 받았던 887명 중 헬리코박터 파일로리 감염 여부가 확인되지 않았거나 추적 기간이 1년 미만인 경우를 제외한 521명의 의무기록을 후향적으로 분석하였다. 이 중 292명에서 감염 양성이었고, 116명에서 제균이 이루어졌으며, 176명에서는 제균 치료를 받지 않았거나 제균에 실패하였다. 결과: 평균 추적 기간은 59.1개월(범위 12-125개월)이었고, 63명(12.18%)에서 이시성 종양이 진단되었다. 다변량 분석에서는 65세 이상의 고령(HR=2.247, 95% CI 1.297-3.895), 종양의 크기(HR=1.283, 95% CI 1.038-1.585), 동시성 병변(HR=2.341, 95% CI 1.244-4.405), 위암의 가족력(HR=3.240, 95% CI 1.776-5.912), 흡연량(HR=1.016, 95% CI 1.003-1.029)이 이시성 종양의 위험인자로 분석되었다. 그러나 헬리코박터파일로리 감염 및 제균 여부는 이시성 위암의 발생과 유의한 관련성을 보이지 않았다(HR=0.641, 95% CI 0.297-1.384). 결론: 헬리코박터 파일로리 제균 치료는 위 이형성의 내시경 절제술 후 이시성 종양 발생을 줄이는 효과는 뚜렷하지 않았다. 이외에 65세 이상의 고령, 종양의 크기, 동시성 병변, 위암의 가족력 및 흡연력은 이시성 위암 발생의 위험요인으로, 내시경 절제술 후 지속적인 내시경 추적 검사가 필요하다. Background/Aims: Helicobacter pylori (Hp) infection is an important risk factor for gastric carcinogenesis. Although several studies have investigated the effect of Hp eradication on the development of metachronous neoplasm after endoscopic resection of the gas-tric dysplasia, the evidence is still insufficient to make a clear conclusion. The aims of this study was to evaluate the risk factors for the development of metachronous neoplasm after endoscopic resection of gastric dysplasia and to investigate the effect of Hp eradication. Methods: Between 2005 and 2011, a total of 887 patients underwent endoscopic resection for gastric dysplasia. Among them, 521 patients who had undergone tests for Hp infection and been followed-up for at least one year were included in the final analyses. Of the 292 Hp-positive patients, 116 patients were successfully eradicated, while 176 failed or did not undergo eradication. Results: During a mean follow-up of 59.1 months (range 12-125 months), metachronous neoplasm had developed in 63 patients (12.1%, dysplasia in 38, carcinoma in 25). In multivariate analyses, age ≥65 (hazard ratio [HR]=2.247, 95% confidence interval [CI] 1.297-3.895), tumor size (HR=1.283, 95% CI 1.038-1.585), synchronous lesion (HR=2.341, 95% CI 1.244-4.405), family history of gastric cancer (HR=3.240, 95% CI 1.776-5.912), and smoking (HR=1.016, 95% CI 1.003-1.029) were risk factors for metachronous neoplasm after endoscopic resection of gastric dysplasia. However, Hp eradication was not associated with metachronous neoplasm (HR=0.641, 95% CI 0.297-1.384). Conclusions: Hp eradication was not shown to be associated with the development of metachronous cancer after endoscopic re-section of gastric dysplasia. (Korean J Gastroenterol 2017;70:27-32)
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천식 환자에서 동반된 위식도역류질환의 양성자펌프억제제 용량에 따른 치료효과
이윤빈 ( Yun Bin Lee ),임주현 ( Joo Hyun Lim ),최윤진 ( Yoon Jin Choi ),김지연 ( Ji Yeon Kim ),손준혁 ( Jun Hyuk Son ),최선미 ( Sun Mi Choi ),조현진 ( Hyun Jin Jo ),신철민 ( Cheol Min Shin ),이상협 ( Sang Hyup Lee ),박영수 ( Young 대한소화기학회 2011 대한소화기학회지 Vol.58 No.4
Background/Aims: Gastroesophageal reflux disease (GERD) is common in asthma patients. Proton pump inhibitor (PPI) therapy improves symptoms of asthma in some patients. The objective of this study was to investigate endoscopic findings of GERD in asthma patients and to assess the effect of gastric acid suppression with the PPIs on symptom improvement and pulmonary function. Methods: From 105 consecutive patients with GERD symptoms during follow up for asthma, 45 patients were enrolled. Patients enrolled to this study were asked about GERD symptoms before and after treating with PPI. Endoscopic findings were described according to Los Angeles classification. The improvement of asthma symptoms and follow-up pulmonary function test were investigated after administration of PPIs. Results: Esophageal symptoms such as heartburn and acid reflux were present in 25 patients (55.6%), and patients without esophageal symptoms were 20 (44.4%). The degree of endoscopic abnormality was not significantly different between groups with or without esophageal symptoms. The improvement of symptoms was seen in 44 patients (97.8%) except 1 patient after administration of PPIs. The number of patients classified to the low-dose group was 7 patients (15.6%) and that of patients classified to the standard-dose group was 38 patients (84.4%). The follow-up pulmonary function test, peak expiratory flow rate (L/sec) was improved in 3 patients (3 of 7, 42.9%) of the low-dose group, and in 24 patients (24 of 38, 63.2%) of the standard-dose group. The improvement of ventilatory function was not significantly different according to dose of PPIs. Conclusions: Treatment with PPIs is expected to improve subjective symptoms and ventilatory function in asthma patients. (Korean J Gastroenterol 2011;58:178-183)
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비결핵성 항산균증과 유사한 방사선학적 소견을 보이는 환자에서 Segniliparus rugosus가 동정된 첫 증례
최선미 ( Sun Mi Choi ),강효재 ( Hyo Jae Kang ),정윤정 ( Yun Jeong Jeong ),임주현 ( Joo Hyun Kim ),최원석 ( Won Seok Choe ),황상현 ( Sang Hyun Hwang ),박진경 ( Jin Kyeong Park ),황보빈 ( Bin Hwang Bo ),이희석 ( Hee Seok Lee ) 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.1
In 2005, a group of mycolic acid-containing bacteria was characterized as belonging to a novel genus, Segniliparus with species Segniliparus rugosus and S. rotundus. We report a case of the S. rugosus isolated from a 54-year-old woman with radiologic features mimicking that of non-tuberculous mycobacteriosis (NTM). When the patient first visited our hospital, an acid-fast bacteria (AFB) smear tested positive and Mycobacterium tuberculosis polymerase chain reaction (TB PCR) was negative in the bronchoalveolar lavage sample. After 2 months, the growing colonies were reported as NTM, but could not be identified because they had died. One year after the initial visit, induced sputum samples showed the same results, positive AFB smear and negative TB PCR. At this point, the growing colonies were identified as S. rugosus. Therefore, we should consider Segniliparus genus as a differential diagnosis for AFB in respiratory specimens in addition to the genus Mycobacterium.
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