Synthesis of Chloral-2-acetothienone and Trichloroethylidene-2-acetothienone, and Reaction of Trichloroethylidene-2-acetothienone with Hydrazines

이효원,이윤영,Lee, Hyo Won,Lee, Youn Young Korean Chemical Society 1975 대한화학회지 Vol.19 No.1

2-Acetothienone과 chloral을 축합시켜 chloral-2-acetothienone을 생성하였으며 이것을 탈수하여 trichloroethylidene-2-acetohienone을 합성하였다. Trichloroethylidene-2-acetothienone과 phenylhydrazine 또는 치환된 phenylhydrazine들과의 반응으로 2-aryl-6-(2-thienyl)-3(2H)-pyridazinone들을 얻었으며 hydrazine과의 반응에서는 3-(2-thienyl)-5-trichloromethyl-2-pyrazoline이 합성되었다. Chloral-2-acetothienone was synthesized from the condensation of 2-acetothienone with chloral, and trichloroethylidene-2-acetothienone was obtained from the dehydration of chloral-2-acetothienone. From the reaction of trichloroethylidene-2-acetothienone with phenylhydrazine or substituted phenylhydrazines 2-aryl-6-(2-thienyl)-3(2H)-pyridazinones were obtained. 3-(2-Thienyl)-5-trichloromethyl-2-pyrazoline was synthesized from the reaction of trichloroethylidene-2-acetothienone with hydrazine hydrate.

Synthesis of the C11-C21 and C13-C21 Fragments of Epothilones from D-Glucose

이효원,최일영,홍용덕,Lee, Hyo Won,Choe, Il Yeong,Hong, Yong Deok Korean Chemical Society 2000 Bulletin of the Korean Chemical Society Vol.21 No.12

Synthesis of 3,6-Dihydro-2H-pyran Subunits of Laulimalide Using Olefinic Ring Closing Metathesis.PartⅡ

이효원,윤서혜,최이일영,장봉용,Lee, Hyo Won,Yun, Seo Hye,Choe, Lee Il Yeong,Jang, Bong Yong Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.11

솔보써말 방법을 이용한 구리분말 제조 및 전자파 차폐제로의 응용

이효원,김수룡,권우택,최덕균,김영희,Lee, Hyo-Won,Kim, Soo-Ryong,Kwon, Woo-Teck,Choi, Duck-Kyun,Kim, Young-Hee 한국재료학회 2006 한국재료학회지 Vol.16 No.5

Copper powders have been widely used in electrically conductive coatings, electrode materials et al. and are very prospective since they are cheaper than noble metal powders such as silver or palladium. In this study, copper powders for metal filler of EMI shielding have been prepared using a solvothermal process from $CuSO_4$, NaOH, Glucose, mixed solvent ($H_2O$: Ethanol) and hydrazine which was used as a reducing agent at various reaction conditions. The prepared copper powders showed finely dispersed spherical shape without agglomerate, uniform morphology, narrow size distribution, high purity and were about 400-700 nm in size. The prepared powders were characterized using XRD, SEM, TGA, XPS, particle size measurement and EMI shielding efficiency.

답리작 춘계포장에서 보리 및 이탈리안 라이그라스와 두과의 혼파비율이 동위원소 희석법 및 차이법을 이용한 질소고정 및 이동에 미치는 영향

이효원,이효진,김원호,윤봉기,고한종,Lee, Hyo-Won,Lee, Hyo-Jin,Kim, Won Ho,Yoon, Bong Ki,Ko, Han Jong 한국초지조사료학회 2016 한국초지조사료학회지 Vol.36 No.4

본 연구는 전남농업기술원 답리작 시험포장에서 2006년과 2007년 사이에 보리와 이탈리안 라이그래스와 각종 두과를 혼파비율을 달리한 처리하여 파종하였다. 주구는 보리 및 이탈리안 라이그래스와 자운영, 크림손클로버, 헤어리벳치, 사료용 완두였고 세구는 화본과와 두과를 각각 50:50, 60:40, 70:30 그리고 80:20이었다. 공중질소 고정량 및 이의 이동을 측정하기 위하여 질소동위원소($^{15}N(NH_4)_2SO_4$)를 2007년 4월 15일 처리 후 쿼드랏 안의 식물체를 6월 8일에 수확하여 화본과 및 두과로 분리한 후 안정성동위원소 질량분석기를 이용하여 분석하였다. 공중질소 고정률은 두과에서 화본과로, 질소이동은 차이법과 동위원소 희석법을 이용하여 구하였다. 본 실험결과의 주요내용은 동위원소 초과는 화본과에서는 차가 없었던 반면 보리와 두과와 혼파비율이 60:40인 처리에서 유의적인 차이가 있었다. 그 값은 보리와 혼파한 두과는 0에서 0.54 범위였다. 이탈리안 라이그래스와 두과 혼파에서는 초과 값이 더 높아 보리에서는 0.71에서 0.82, 두과는 0.37에서 1.01 사이였다. 공중 질소 이용비율은 보리와의 조합은 0%~49.5%, 이탈리안 라이그라스 조합은 0~60.5%의 범위로 다양한 결과를 나타내었다. 차이법에 의한 이동량 시험에서는 보리와의 조합에서 12.3~90.9 kg/ha, 이탈리안 라이그래스 조합에서는 보리보다 더 많아 31.7~107.8 kg 사이였다. 한편 동위원소 희석법에서는 보리와 두과 혼파조합은 0~36.1 kg/ha 그리고 이탈리안 라이그래스와 두과 혼파에서는 0~50.6 kg/ha로 이탈리안 라이그래스 조합이 더 많은 것으로 나타났다. 차이법에 의한 질소 이동량이 동위원소 희석법보다 더 많은 것으로 나타났다. In order to study the effect of barley, Italian ryegrass (IRG), and legume mixture on nitrogen fixation and transfer to grasses on spring paddy field, an experiment was carried out from Oct. 2006 to June 2007 in Naju, Korea. A split plot design with three replications was used for the experiment. One reference plot was assigned for each treatment to determine nitrogen fixation. Main plots consisted of Chinese milk vetch, crimson clover, forage pea, and hairy vetch with barley, respectively. Subplot treatment were barley or IRG with four seeding ratio of legumes (50:50, 60:40, 70:30, and 80:20). To estimate N fixation by legumes, $^{15}N$ isotope dilution technique was used. $^{15}N$ fertilizer [$(^{15}NH_4)_2SO_4$ solution at 99.8 atom N] was uniformly applied to $600cm^2$ in the middle of each plot on April 15, 2007. Plots were harvest by hand on June 8, 2007. Dried sample were ground to a fine power and analyzed for total N isotope N. $^{15}N$ was determined using elemental analyzer-isotope ratio mass spectrometry. The calculation of N transfer was determined with the isotope dilution method. The content of N was higher in legumes than that in barley or Italian ryegrass. Nitrogen level in forage pea was significantly higher than that of other legumes. There were significantly differences in N content between legumes in IRG mixture. Atom % $^{15}N$ excess was significantly different in legumes with barley. The 60:40 sub plot had higher (p<0.05) atom % $^{15}N$ than other seeding ratio treatments. The enrichment ranged from 0 to 0.58. Compared to barley, the enrichment of IRG with its accompanied legumes was higher, ranging from 0.38 to 1.0. The N derived from the atmosphere (Ndfa) ranged from 0% to 49.5% with barley-legume mixture. It ranged from 0 to 60.5% in IRG-legume plots. N transfer from legumes to neighboring grasses was 12.3 to 90.9 kg/ha for barley-legume mixture and 31.7 to 107.8 kg/ha for IRG plots. IRG plots showed higher N transfer for IRG-legume mixture in general based on difference method. Based on $^{15}N$ dilution method, the N transfer was 0 to 36.1 kg/ha for barley-legume mixture and 0 to 50.6 kg/ha for IRG plots. There was a tendency toward higher N transfer on the difference method than that of the $^{15}N$ dilution method.

트리암시놀론이 배양된 사람 섬유아세포의 생존과 산화질소 생성에 미치는 영향

이효원,김재우,Hyo-Won Lee,Jae-Woo Kim 대한안과학회 2005 대한안과학회지 Vol.46 No.11

Purpose: To investigate the effect of triamcinolone acetonide (TA) on cell survival and nitric oxide (NO) production in cultured human Tenon`s capsule fibroblast (FB) cells. Methods: After exposed to TA, indomethacin, and dexamethasone for 2 days, cell survival and nitrite production of primarily cultured human FB cells were assessed with MTT and Griess assays, respectively. Results: Cell survival increased after exposure to TA at low concentrations but decreased at high concentrations. TA decreased the production of NO significantly (p<0.05). Exposure to indomethacin and dexamethasone revealed similar results. Conclusions: Both the biphasic effect on cell survival and the decreased production of NO induced by TA in FB cells could affect conjunctival wound healing

Synthesis of 3,6-Dihydro-2H-pyran Subunits of Laulimalide Using Olefinic Ring Closing Merathesis. PartⅠ

이효원,정충식,윤수혜,이일영최,Lee, Hyo Won,Jeong, Chung Sik,Yun, Su Hye,Lee, Il Yeong Choe Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.8

나주, 천년의 역사, 그리고 가능성

이효원,Lee, Hyo-Won 대한건축사협회 1999 建築士 Vol.1999 No.5

사초용 피 ( 삼 )의 생산에 관한 연구 1 . 3종 피 ( 삼 )의 생육특성 및 사초 ( 飼草 )생산성 비교

이효원 ( Hyo Won Lee ) 한국축산학회 1981 한국축산학회지 Vol.23 No.3

Agronomic characteristics and yield performance trial of 3 Japanese millet cultivars has been made at Suweon for 3 years, 1978-1980. The annual forages involved were Korean native millets, Jeju and Jinju, and Chiwapa millet introduced from U. S. A. The results of the study are summarized as follows: 1. There were little differences among three cultivars in plant height. Jinju millet gave the widest leaf width (2.5㎝) and produced soft fresh forage, followed by Jeju millet (2.1㎝), and Chiwapa millet was very narrow (1.4㎝) in leaf width and coarse compared with Korean native millets. 2. Dry matter yield of Jeju millet (924㎏/l0a) and Jinju millet (913㎏/l0a) were significantly higher than that of Chiwapa, produced only 745㎏/l0a (P$lt;0.05), however, there was no significant difference between Jeju millet and Jinju millet. 3. Therefore, it is suggested that Jeju and Jinju millets are desirable to grow under our condition; for summer forage.

적생조래(荻生徂徠)와 통신사 -조래(徂徠) 조선관의 형성과 계승에 주목하여-

이효원 ( Hyo Won Lee ) 한국고전문학회 2013 古典文學硏究 Vol.43 No.-

본고는 18세기 일본의 사상가 적생조래(荻生徂徠)가 통신사, 나아가 조선에 대해 어떤 생각을 가지고 있었는지 탐색하는 것을 목적으로 한다. 지금까지의 소라이 연구가 주로 일국사적(一國史的)인 관점에서 사상(思想)을 탐구하는 데 초점이 맞추어진 것에 비해, 본 연구에서는 동아시아라는 맥락에서 상대화함으로써 그동안 간과되어 왔던 소라이의 독특한 면모를 몇 가지 밝혀낼 수 있었다. 첫 번째는 소라이가 통신사에 대해 적대감 내지는 편견을 가지고 있었다는점이다. 소라이는 자기 학파의 위상을 확립하기 위해 통신사의 시를 극렬하게 비판하였으며, 조선이 문학적 역량으로 일본을 굴복시키려 한다는 왜곡된 인식을 드러냈다. 두 번째는 소라이가 통신사를 폄하하면서도, 한편으로는 통신사에 대한 선망을 지니고 있었다는 점이다. 이것은 중화문명에 대한 동경에서 비롯된 것이다. 그러나 한편으로 조선이 풍신수길(豊臣秀吉)의 무력에 굴복하였으며 통신사가 일본에 조공을 바치러 온 것이라는 왜곡된 역사인식을 보이기도 하는데, 이는 당대 일본 지식인이 공통적으로 가지고 있던 자국중심주의와 상통한다. 세 번째는 소라이의 조선에 대한 왜곡된 인식이 소라이 학파 내부에서 계승되어 간 점이다. 1763년 통신사와 논쟁을 벌인 구정남명(龜井南冥)에게서 이 점을 확인할 수 있었다. 이러한 인식은 복택유길(福澤諭吉)에게까지 이어져 근대 일본이 조선을 침략하는 근거로 작용하였다. In this paper I try to research what idea Ogyu Sorai(荻生徂徠) had about Tongsinsa(通信使) and Chosun(朝鮮). Until now, most studies of the Sorai are research of thought on a national history. But I try to search some peculial side of Sorai on a East Asia History. This point of view, first, Sorai had hostility or prejudice on the Tongsinsa. Sorai severely criticized chinese poetry of Tongsinsa, and he had distorted recognition that Chosun try to bring Japan to knees. Second, Sorai disparaged Tongsinsa, on the other hand, longed for Tongsinsa. It is originated from Chinese ancient civilization. Also he think that Chosun gave in force of Toyotomi Hideyoshi(豊臣秀吉) and have distorted perception of history that Tongsinsa come to pay tribute to Japan. It is similar to the nationality which most of Japan intellect have in The Edo(江戶) period. Third, Sorai`s distorted perception of Chosun succeed to a school of Sorai. We confirm it at the dispute between Kamei Nanmei(龜井南冥) and Tongsinsa. Sorai`s perception is also succeed to Hukuzawa Yukichi(福澤諭吉) and be based of invasion of Chosun.