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반하사심탕(半夏瀉心湯)이 Doxorubicin에 의해 유발(誘發)된 간장(肝臟) 및 비장(脾臟) 독성(毒性)에 미치는 영향(影響)
황희정,신민규,곽민아,이윤희,김상찬,변준석,Hwang, Hui-Jeung,Shin, Min-Kyu,Kwak, Min-Ah,Lee, Yun-Hee,Kim, Sang-Chan,Byun, Joon-Seok 대한암한의학회 2002 大韓癌韓醫學會誌 Vol.8 No.1
Object The effect of Banhasasim-tang extracts on the hepatic, splenic toxicity and induced by Doxorubicin administration(Three injection protocol) were monitored using male ICR mice. Method The changes of body weigh, organ weights of liver and spleen were observed with blood GOT and GPT level. Results 1. Increase of absolute and relative liver weight observed in Doxorubicin treatment group were dose-dependently inhibited by Banhasasim-tang extracts. In addition, the degrees of liver congestion and necrotic spot were significantly and dose-dependently decreased after Banhasasim-tang extracts dosing groups compared to that of Doxorubicin treatment group. It is also demonstrated that elevated serum GOT and GPT levels in Doxorubicin treatment group were significantly decreased in Banhasasim-tang extracts dosing groups. 2. Decrease of absolute and relative spleen weight observed in Doxorubicin treatment group were dose dependently inhibited by Banhasasim-tang extracts. In addition, the degrees of splenic atrophy were significantly and dose-dependently decreased after Banhasasim-tang extracts dosing groups compared to that of Doxorubicin treatment group.
동원(東垣) ${\ll}$비위론(脾胃論)${\gg}$ 수록(收錄) 처방(處方)의 치법(治法)에 대(對)한 문헌적(文獻的) 고찰(考察)
이윤희,황희정,김상찬,박순달,변준석,Lee, Yun-Hee,Hwang, Hui-Jeung,Kim, Sang-Chan,Park, Soon-Dal,Byun, Joon-Seok 대한한의학방제학회 2001 大韓韓醫學方劑學會誌 Vol.9 No.1
Objectives : 'Pi Wei Lun' is the principal medical work of Li Dongyuan's writings, which contains most of his medical theories. There are sixty-three prescriptions in 'Pi Wei Lun', and fifty-two of them were originated from him. This study was planned to present assistance to those who apply Dongyuan's theory clinically. Methods : We investigated those fifty-two prescriptions literary, and studied them from a viewpoint of the principle and method of treatment. Results : Dongyuan's fifty-two prescriptions can be classified into eight groups from the viewpoint of the principles and methods of treatment which are composed of 'tonify the spleen and stomach & elevate the spleen Yang', 'elevate the spleen Yang & expel fire', 'elevate the spleen Yang & relieve dampness', 'promote blood flow to eliminate blood stasis', 'invigorate the spleen', 'replenish Ki & and dispel phlegm', 'purgation with drugs warm in nature', and 'the other' eight methods. Conclusions : From above, we concluded that Dongyuan considered 'the primordial energy of the spleen and stomach' as the most important when making up prescriptions, but, at the same time, he used diverse methods of treatment on the ground of differentiation of syndromes.
이윤희,김종대,황희정,Lee, Yoon-Hee,Kim, Jong-Dea,Hwang, Hui-Jeung 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.4
We extended to find out the effect of serveral kinds of herbal medicion that administated to the patient suffer from iron deficiency anemia, that was prescribed according to differentiation of syndromes. Iron deficiency anemia is generlly differentiated as defiency of Ki and blood, hypofunction of the spleen and stomach, and insufficiency of the spleen and kidney in orinetal medicine. This patient was differentiated as defiency of Ki and blood. hypofunction of the spleen and stomach. So we prescribed Hyangsayangwi-tang, Ickibohyoul-tang and Ickibohyoul-tang ga Antler for the patient in turn. When administated Hyangsayangwi-tang and Ickibohyoul-tang, there was a little improvement in symptom but no improvement in hemonalysis. When administrated Ickibohyoul-tang ga Antler there was dominent improvement in both of symptom and hemonalysis. From this case. it is thought that added Antler-tonifying recipe is very effective to iron deficiency anemia and that more studies and examinations are needed in futher.
증례 : 순환기 ; 발열을 동반한 폐렴환자에서 발견된 특발성 Brugada 심전도 패턴 1예
이재범 ( Jae Beom Lee ),이만영 ( Man Young Lee ),이성진 ( Sung Jin Lee ),황희정 ( Hui Jeong Hwang ),박현근 ( Hyun Keun Park ),최윤석 ( Yun Seok Choi ),박철수 ( Chul Soo Park ) 대한내과학회 2011 대한내과학회지 Vol.80 No.2S
저자 등은 44세의 남자 환자에서 늑막염을 동반한 폐렴으로 인한 급성 흉통과 발열과 동반된 ST분절 상승으로 급성심근 경색으로 오인하였고, flecainide 유발검사로 특발성 Brugada 심전도 pattern이 진단되었던 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. We present the case of a 44-year-old man who presented with continuous chest pain and fever with pneumonia. Additionally, idiopathic Brugada ECG patterns were observed. The patient`s initial electrocardiogram showed ST-segment elevation at the right precordial and lateral leads. An emergency coronary angiography showed that there was no significant stenosis or thrombus in the coronary arteries. ECG findings showed Brugada ECG patterns, which were exaggerated by high fever. The diagnosis was confirmed with a flecainide provocation test that allowed us to document ECG changes consistent with type 1 Brugada ECG patterns. This case report reveals how dynamic ST-segment elevations may look similar in cases of acute coronary syndrome and Brugada syndrome. Additionally, we showed that Brugada ECG patterns can be exaggerated by fever. (Korean J Med 2011;80:S166-S171)