남성 불임 환자의 하복부 온도에 관한 임상적 고찰

이창훈,조정훈,장준복,이경섭,위효선,Lee, Chang-Hoon,Cho, Jung-Hoon,Jang, Jun-Bock,Lee, Kyung-Sub,Wee, Hyo-Sun 대한한방체열의학회 2005 대한한방체열의학회지 Vol.4 No.1

Purpose : To examine the relation between male infertility and cold hypersensitivity on lower abdomen. Methods : From 2004, 4 to 2005, 10, a total 60(infertile male 30, normal male on semen analysis 30) patients who visited the Oriental gynecological department of Conmaul Oriental Medicine hospital was selected, and their medical records were reviewed retrospectively. We compared the temperature of 3 points(CV17, CV12, CV4) of both group by DITI(Dorex, DITI-16UTI and DITI-Spectrum 9000 MB). Results and Conclusion : The general characteristics such as age, weight, height, BMI, amount and frequency of drinking and smoking of both group were not different statistically. The mean ${\Delta}T1$ between upper and lower abdomen in infertile group was higer than in normal group but they were not different statistically. The mean ${\Delta}T2$ between chest and lower abdomen was $0.46{\pm}0.41$ in infertile group, and $0.18{\pm}0.56$ in normal group, and it shows significant difference statistically. There was no significant relationship between sperm motility and ${\Delta}T1$, ${\Delta}T2$ in infertile group. In this study, we suggest that an inclination of cold hypersensitivity of lower abdomen of infertile male, but it is expressed when it is contrasted to chest of the body rather than upper abdomen.

단치소요산(丹梔逍遙散) 약침(藥鍼)의 소염(消炎), 진통(鎭痛) 및 해열(解熱) 효과(效果)에 대한 실험적(實驗的) 연구(硏究)

이창훈 ( Chang-hoon Lee ),장준복 ( Jun-bock Jang ),이경섭 ( Kyung-sub Lee ),송병기 ( Byoung-key Song ) 대한한방부인과학회 2001 大韓韓方婦人科學會誌 Vol.14 No.3

Objective - Experimental trials on Danchisoyo-San solution were made before. This trial is to examine the effects of Danchisoyo-San Aqua-acupuncture as an analgesic, antiphlogistic and antifebrile. Methods - Danchisoyo-San was, through evaporation, made into extract. The extract concentration was 210mg/kg, calculated in terms of raw material, and diluted with saline solution when necessary. Extract was injected into Gi-Mun, LR14. This trial involved for groups: a control group injected with saline solution, Sample-A group and Sample-B group with extract of 105mg/kg and 210mg/kg concentration, respectively, and the fourth group with comparative treatment. The effects as an analgesic, antiphlogistic and antifebrile were examined. Conclusion 1) In acute edema, the Danchisoyo-San Aqua-acupuncture groups showed reliable results in inhibiting Carrageenin-caused edema. 2) In histamine-caused vascular permeability increase, only the group of Danchisoyo-San extract of 210mg/kg showed reliable results in inhibiting the increase. 3) Analgesic effects of Danchisoyo-San Aqua-acupuncture, through writhing syndrome induced acetic acid and Hat Plate Analgesia Meter, proved to be reliable both in Sample-A and Sanple-B group and the effects especially through writhing syndrome induced acetic acid , proved to be more reliable in the latter group than in the former 4) Regarding the effects of Pentobarbital-Na on lengthening of sleeping hours and voluntary mobility, only the Danchisoyo-San Aqua-acupuncture groups showed reliable changes. 5) In body temperature, both Sample-A and Sample-B group showed no reliable change.

Ga-stabilized GaAs(100) 표면에서의 Na 화학흡착에 대한 분자궤도함수론적 연구

이창훈,장재용,박영환,강진희,이홍,황용규,이기학,Lee, Chang-Hoon,Jang, Jae-Yong,Park, Young-Hwan,Kang, Jin-Hui,Lee, Hong,Hwang, Yong-Gyoo,Lee, Kee-Hag 대한화학회 2005 대한화학회지 Vol.49 No.1

칠제향부환(七製香附丸)이 원발성(原發性) 월경통(月經痛) 환자(患者)의 복부(腹部) 온도(溫度)에 미치는 영향(影響)

이창훈,조정훈,장준복,이경섭,윤영진,Lee, Chang-Hoon,Cho, Jung-Hoon,Jang, Jun-Bock,Lee, Kyung-Sub,Yoon, Young-Jin 대한한방체열의학회 2005 대한한방체열의학회지 Vol.4 No.1

Purpose: We intended to observe the relations between Chiljehyangbuhwan and abdominal temperature according to primary dysmenorrhea severity. Methods: We selected the 100 primary dysmenorrhea patients by the screening tests (first screening test-inquiry, second screening test-clinical test, additionally WHR (Waist-to-Hip ratio) by Inbody 2.0). By the fixed blocked randomization and double blind method, Chiljehyangbuhwan or placebo was administered for 1 menstration period. Finally, 69 patients remainded. Before and after administration, we measured 4 points abdominal temperature (Chon-jung(CV17), Chung-wan(CV12), Kwan-won(CV4), Chung-guk(CV3)) by DITI (DOREX Inc., USA). And then we checked the difference of temperature $({\Delta}T)$ between CV17 and CV12 / CV17 and CV4 / CV17 and CV3 / CV12 and CV4 / CV12 and CV3. After that, we compared ${\Delta}T$ with primary dysmenorrhea severity evaluated by VRS (verbal rating scale) and MVRS (multidimensional verbal rating scale). In dysmenorrhea severity, we standardized scale score and 3-group-severity by score (mild, moderate, severe). For statistics, we used Pearson correlations and Spearman's rho correlations, SPSS 11.0 for windows. Results: In case of MVRS, Chiljehyangbuhwan was correlated to ${\Delta}T$ (CV12 and CV3 / CV12 and CV4). In case of VRS, Chiljehyangbuhwan was not correlated to ${\Delta}T$. Statistically they showed significant result (p<0.05). Conclusion: The primary dysmenorrhea patients showed that severity by MVRS was connected with ${\Delta}T$ (CV12 and CV3 / CV12 and CV4) after Chiljehyangbuhwan administration. So we can consider Chiljehyangbuhwan effects the abdominal temperature according primary dysmenorrhea severity.

국내 원자력 발전소 주변 토양 휴믹산의 추출 및 특성 규명

이창훈,신현상,정근호,조영현,이창우,Lee, Chang-Hoon,Shin, Hyun-Sang,Chung, Kun-Ho,Cho, Young-Hyun,Lee, Chang-Woo 대한방사선방어학회 2003 방사선방어학회지 Vol.28 No.3

본 연구에서는 국내 원자력발전소가 위치한 지역의 토양(영광, 울진, 고리, 고성, 월성)에 존재하는 휴믹산(HA)을 추출하여 각 시료의 원소성분 및 분광학적 방법(UV/Vis, IR, CPMAS $^{13}C$ NMR)을 이용한 물질 특성을 조사하였고, Aldrich HA과 함께 비교 분석하였다. 분자량 크기 분포의 차이는 한외여과법을 이용하여 조사하였다. 원소분석 결과, 울진 지역의 HA에서 가장 높은 산소 함량비를 보였으며, 고리와 고성지역의 HA에서 상대적으로 낮은 산소 함량비를 보였다(O/C: 0.51(UJHA) vs. 0.43(KRHA), 0.46(KSHA)). 분자량 크기 분포는 울진과 영광 지역의 HA가 고리와 고성 지역의 HA에 비하여 30,000 daltons이상의 고분자가 더 높게 존재함을 알 수 있었다. CPMAS $^{13}C$ NMR, UV/Vis., IR 등의 분광학적 특성분석 결과, 울진과 영광 지역의 HA가 고리, 고성 및 월성 지역의 HA에 비하여 상대적으로 높은 방향족성(aromaticity)과 산소 포함 작용기의 함량이 높은 특성을 보였다. 이상의 결과로 볼 때, 울진과 영광지역의 HA가 상대적으로 더 높은 휴믹화(humification) 단계의 물질 특성을 가짐을 알 수 있었으며, 금속이온과의 반응성이 더 높을 것으로 예측된다. Humic acids present in the soils at the vicinity of domestic atomic power plants(NPPs), located in Yeongkwang(YK), Uljin(UJ), Kori(KR), Koseong(KS), Wolseong(WS) area were isolated, and characterized using elemental analysis and UV/Vis, IR, CPMAS $^{13}C$ NMR spectroscopic methods. The characteristics were compared with one another and with commercial humic acid (Aldrich Co.). Molecular size distributions of the humic acids were determined using a stirred cell ultrafiltration technique. The results of elemental analysis showed that soil humic acid from UJ contains higher oxygen content than humic acids from KR and KS (O/C ratios: 0.51 (UJHA) us. 0.45(KRHA), 0.43(KSHA)). The molecular size distribution revealed that the soil humic acids of UJ and YK contained a higher percentage of larger molecules of > 30,000 daltons, compared to those of KR and KS. The spectral features obtained from UV/vis., IR and CPMAS $^{13}C$ NMR showed that the aromatic character and oxygen containing functional groups in the humic acids from UJ and YK were relatively higher than those of KR and KS. These results indicate that the soil humic acids from UJ and YK were in a higher degree of humification, which may suggest higher affinity of the humic acids with radionuclides released in the soil environments.

DITI를 이용한 교통사고 환자의 한의학적인 치료평가

이창훈,조정훈,장준복,이경섭,황재호,Lee, Chang-Hoon,Cho, Jung-Hoon,Jang, Jun-Bock,Lee, Kyung-Sub,Hwang, Jae-Ho 대한한방체열의학회 2005 대한한방체열의학회지 Vol.4 No.1

Purpose: This study is to assess oriental medicine treatment for cervical sprain from traffic accident using DITI. Methods: 21 patients who hospitalized in the Kangnam Korean Hospital, KyungHee Univ. from March 1, 2004 to September 30, 2005 diagnosed as cervical sprain from traffic accident were participated in this study. They received acupuncture treatment, Herb medicine, ICT-Tx, and Nega-Tx during the admission period. We checked temperature of neck(A area) and whole back(B area) and ${\Delta}T$ were calculated at admission date(pre-Tx group, ${\Delta}T1$) and discharged date(post-Tx group, ${\Delta}T2$). Results: ${\Delta}T2$ decreased significantly in post-Tx group compared with ${\Delta}T1$ in pre-Tx group Conclusion: Oriental medicine treatment can be the effective way to treat cervical sprain from traffic accident. and DITI can be useful instrument to assess oriental medicine treatments.

칠제향부환(七製香附丸)이 원발성(原發性) 월경통(月經痛) 환자(患者)의 복부(腹部) 및 수장부(手掌部) 온도(手掌部 溫度)에 미치는 영향(影響)

이창훈,조정훈,장준복,이경섭,윤영진,Lee, Chang-Hoon,Cho, Jung-Hoon,Jang, Jun-Bock,Lee, Kyung-Sub,Yoon, Young-Jin 대한한방체열의학회 2006 대한한방체열의학회지 Vol.5 No.1

Purpose: We intended to observe the relations between Chiljehyangbuhwan and abdominal & palmar temperature according to primary dysmenorrhea severity. Methods: We selected the 100 primary dysmenorrhea patients by the screening tests (first screening test-inquiry, second screening test-clinical test. additionally WHR (Waist-to-Hip ratio) by Inbody 2.0). By the fixed blocked randomization and double blind method, Chiljehyangbuhwan or placebo was administered for 1 menstration period. Finally, 69 patients remainded. Before and after administration, we measured 4 points abdominal temperature (Chon-jung (CV17), Chung-wan(CV12), Kwan-won(CV4). Chung-guk(CV3)) by DITI(DOREX Inc., USA). And then we checked the difference of temperature $({\Delta}T)$ between CV17 and CV12/CV17 and CV4/CV17 and CV3/CV12 and CV4/CV12 and CV3. Also, we measured 2 points (palmar region, upper front of forearm) for the difference of palmar temperature $({\Delta}T)$. Then, we checked palmar temperature minus upper front of forearm temperature and took an average of right and left ${\Delta}T.$ After that. we compared ${\Delta}T$ with primary dysmenorrhea severity evaluated by VRS (verbal rating scale) and MVRS (multidimensional verbal rating scale). In dysmenorrhea severity. we standardized scale score and 3-group-severity by score (mild, moderate. severe). Besides, we compared palmar ${\Delta}T$ with abdominal ${\Delta}T$. For statistics, we used ANOVA and Spearman's rho correlations. SPSS 13.0 for windows. Results: In case of MVRS, though Chiljehyangbuhwan was correlated to abdominal ${\Delta}T$(CV12 and CV3/CV12 and CV4). it was not correlated to palmar ${\Delta}T$. In case of VRS, though Chiljehyangbuhwan was not correlated to abdominal ${\Delta}T$. it was correlated to palmar ${\Delta}T$. However. palmar ${\Delta}T$ was not correlated to abdominal ${\Delta}T$. Statistically they showed significant result (p<0.05). Conclusion: The primary dysmenorrhea patients showed that severity by MVRS was connected with abdominal ${\Delta}T$ (CV12 and CV3/CV12 and CV4) and severity by VRS was connected with palmar ${\Delta}T$ after Chiljehyangbuhwan administration. So we can consider Chiljehyangbuhwan partially effects the abdominal & palmar temperature according primary dysmenorrhea severity. However, palmar temperature was not correlated to abdominal temperature. Therefore, we need further study.

온라인 게임 상의 사용자 인증에 적용 가능한 셀룰러 오토마타 기반 해쉬함수에 대한 충돌쌍 공격

이창훈,이제상,조성언,김태훈,김수균,Lee, Chang-Hoon,Lee, Je-Sang,Cho, Sung-Eon,Kim, Tai-Hoon,Kim, Soo-Kyun 한국정보통신학회 2009 한국정보통신학회논문지 Vol.13 No.2

본 논문에서는 온라인 게임 상의 사용자 인증에 적용 가능한 이차원 셀룰라 오토마타 기반 해쉬함수에 대한 충돌쌍 공격을 제안한다. 이것은 라운드 함수에서 사용되는 비선형 함수의 비선형 성질을 이용하여 입력된 베시지 차분을 확률 $2^{-28}$으로 상쇄시키는 공격이다. 또한, 최근 발표된 Wang의 분석 기법을 이용하여 확률 1로 만족하는 충돌쌍 공격을 제시한다. In this paper, we. present a collision attack on hash function with 2-dimensional cellular automata[1], which is useful for providing authentication on online game. This attack can find a collision message pair with $2^{28}$ computation using property of nonlinear function. We also extend basic attack with probability $2^{-28}$ to improve attack with probability 1 using Wang's analysis technique.

맥파전달속도(PWV)와 말초체열분포(DITI)와의 관계 연구

이윤재,조정훈,이창훈,이진무,장준복,이경섭,Lee, Yoon-Jae,Cho, Jung-Hoon,Lee, Chang-Hoon,Lee, Jin-Moo,Jang, Jun-Bock,Lee, Kyung-Sub 대한한방체열의학회 2008 대한한방체열의학회지 Vol.6 No.1

Objective: The purpose of this study is to identify relationship between the PWV and the temperature difference. Methods: When it comes to senile patients who suffer from cold limbs, there is need to see whether or not the patient's low temperature of the limbs is do to arteriosclerosis. The Pulse Wave Velocity(PWV) is a non-invasive method measuring the artery's rigidness. And the Digital Infrared Thermal Imaging(D.I.T.I) is a non-invasive method to see the body's thermal change. Research on the interrelationship of the artery's rigidness and body's thermal distribution was done by using these two tests. The subjects of this research were patients between the age 40~65 who have done both the D.I.T.I and PWV in March 2005~ September 2005. They had to have no history of diabetes, coronary illnesses or cerebrovascular diseases which are diseases that can effect the outcome of the PVW, nor history of spondylopathy or dermatosis which can effect the outcome of the D.I.T.I. Results: The results were as follows. 1. There was a significant interrelationship between the right wrist-ankle PWV and the temperature difference of the right wrist-palm. 2. There was a significant interrelationship between the left wrist-ankle PWV and the temperature difference of the left wrist-palm. 3. There was no significant interrelationship between the right wrist-ankle PWV and the temperature difference of the right thigh-dorsum of foot. 4. There was no significant interrelationship between the left wrist-ankle PWV and the temperature difference of the left thigh-dorsum of foot. 5. The right ABI showed no significant interrelationship between the temperature difference of the right wrist-palm and the right thigh-dorsum of foot. 6. The left ABI showed no significant interrelationship between the temperature difference of the left wrist-palm and the left thigh-dorsum of foot. Conclusion: The study shows that there was a significant interrelationship between wrist-ankle PWV and the temperature difference of wrist-palm.

2016국민환경의식조사 연구

곽소윤 ( So-yoon Kwak ),이창훈 ( Chang-hoon Lee ),임용빈 ( Yong-bin Im ) 한국환경정책평가연구원 2016 한국환경정책평가연구원 기초연구보고서 Vol.2016 No.-

본 연구는 정기적으로 환경 전반에 대한 국민의 의식과 태도를 파악하기 위하여 기획되었으며, 매해 반복되는 기본부문과 당해 연도 정책이슈를 다루는 특별부문으로 구성된 2016년 국민 환경의식조사를 수행하고 환경에 대한 국민들의 인식을 살펴보았다. 2012년부터 시작된 국민환경의식조사의 기본 부문은 환경인식, 환경의식 및 태도, 환경 실천, 환경정책 수요, 삶의 질·지속가능성 부문으로 구성된다. 2016년 조사에서는 기후변화와 미세먼지가 특별 부문의 주제로 선정되었다. 본 설문조사는 전국의 만 19세 이상 69세 이하 성인 남녀 1,000명을 대상으로 조사전문기관의 방문면접조사를 통해 수행되었다. 환경 하면 떠오르는 이미지로 ‘기후 변화’라는 응답이 가장 높게 나왔고, 환경에 대한 만족도는 ‘자연 경관’에 대해 높게 나타났다. 국민의 과반수가 평소 환경문제에 대해 관심을 가지고 있는 것으로 나타났고, 환경보전이 개인에게 중요한 정도는 2015년에 비해 약간 감소하였으나 여전히 높은 수준을 보이며 국민의 대다수가 환경을 중요하게 생각하는 것으로 파악되었다. 생태주의적 세계관을 나타내는 점수는 2012년 조사 시작 이래 2015년까지 증가해오다 올해 조사 결과에서는 다소 감소하였다. 가장 우려하는 환경문제로는 ‘쓰레기 증가’를 꼽았고, 정보가 부족하다고 생각되는 환경문제로는 ‘자연자원의 고갈’을 응답하였다. 한편 환경오염 및 훼손에 대한 책임은 일반국민에게 있다고 생각하지만, 환경보전에 대한 책임은 주로 중앙정부에 있다고 생각하는 것으로 나타났다. 특별부문인 기후변화에서는 대부분의 응답자가 기후변화에 대해 인지하고 있는 것으로 나타났으며, 기후변화 하면 가장 먼저 떠오르는 이미지로 ‘평균 기온 상승’을 응답하였다. 대다수의 국민이 미세먼지에 관심을 가지고 있으나 우리나라의 미세먼지 수준에 대해서는 불만족스러워하는 것으로 나타났다. 또한 정부의 미세먼지 감축 노력에 대해서는 과반수의 국민이 부족하다고 느끼고 있는 것으로 파악되었다. 이와 같은 연속적인 국민환경의식조사 결과에 대한 정보를 통해 국민들의 인식 및 태도를 파악하고, 나아가 조사결과가 다양한 분석의 기초자료로 활용되어 정책의 활용도를 높이는 데에 일조하기를 기대한다. This study was planned to identify public awareness of and attitudes towards the environment on a regular basis. It conducted the 2016 survey of public attitudes towards the environment, which is consisting of the yearly repetitive basic parts and the special parts discussing issues of the year, and reviewed public awareness of the environment. The basic parts of the survey of public attitudes towards the environment that started from 2012 are composed of environmental perception, awareness of and attitudes towards the environment, environmental practice, demands for the environmental policies, and quality of life and sustainability. In the survey in 2016, climate change and particulate matter were selected as the subjects of the special parts. The survey was carried out on 1,000 men and women aged 19-69 years across the country through a face-to-face interview by a specialized survey agency. The image most associated with the environment was ‘climate change’, and the satisfaction for the environment was high with ‘natural landscape.’ It was identified that the majority of people were interested into the environmental issues in their everyday life. While the importance of environmental conservation to individuals slightly dropped from 2015, it was still high and most people was considering that the environment matters. The score of ecological world view had increased to 2015 from 2012 but slightly decreased this year. People chose ‘a rise in garbage’ as their most concerned environmental issue and ‘lacking natural resources’ as an environmental issue that they did not have enough information. On the other hand, people thought that the public was responsible for environmental pollution and damages but the central government should be held accountable for environmental conservation. In the special parts about climate change, most of the respondents were aware of climate change and answered that the image most associated with climate change was ‘average temperature rise’ It was figured out that most of the people were interested in particulate matter but dissatisfied with the level of particulate matter in South Korea. In addition, the majority of people thought that the government’s efforts to reducing particulate matter were not enough. It is expected to identify public awareness of and attitudes towards the environment based on the results of the annual survey of public attitudes towards the environment, and that the results can contribute to making policies as a fundamental data for various analyses.