사군자탕(四君子湯)의 항염증 효능 연구

이진아,하혜경,정다영,이호영,이남헌,이준경,서창섭,김정훈,이미영,신현규,Lee, Jin-Ah,Ha, Hye-Kyung,Jung, Da-Young,Lee, Ho-Young,Lee, Nam-Hun,Lee, Jun-Kyoung,Seo, Chang-Seob,Kim, Jung-Hoon,Lee, Mee-Young,Shin, Hyeun-Kyoo 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.1

Objectives : To provide the information of efficacy for Sagunja-tang (Sijunzi-tang; SG), it was evaluated the anti-inflammatory effect. SG, a widely used herbal formula in tranditional Korean medicine, has been used to treat for the Boki-invigorating. In many studies, plant-derived anti-inflammatory efficacies have been investigated for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory effects of SG extract on LPS-stimulated RAW 264.7 cells. Methods : The productions of nitric oxide (NO), prostaglandin (PG)$E_2$, interleukin (IL)-6 and tumor necrosis factor (TNF)-$\alpha$ were examined in a macrophage cell line, RAW 264.7 cells, in the presence of the SG extract. RAW 264.7 cells were incubated with LPS $1\;{\mu}g/mL$ and SG extract for 18 hours. The anti-inflammatory activity of SG was investigated by carrageenin-induced paw edema in rats. The paw volume was measured at 0, 2 and 4 hours following carrageenin-induced paw edema in rats. Results : SG extract showed inhibitory effect on $PGE_2$, IL-6 and TNF-$\alpha$ by LPS-stimulated RAW 264.7 cells. But SG extract was not inhibitory effect on NO by LPS-stimulated RAW 264.7 cells. And administration of SG extract (1 g/kg) showed a reduction in carrageenin-induced paw edema on rats. Conclusions : These results suggest that SG extract has anti-inflammatory activities in vitro and in vivo models.

사상 체질 처방의 항염증 효능 비교 연구

이진아,하혜경,이호영,정다영,이준경,황대선,신현규,Lee, Jin-Ah,Ha, Hye-Kyung,Lee, Ho-Young,Jung, Da-Young,Lee, Jun-Kyoung,Huang, Dae-Sun,Shin, Hyeun-Kyoo 사상체질의학회 2010 사상체질의학회지 Vol.22 No.4

1. Objectives 4 herbal formulas (Yanggyeoksanhwa-tang, Yeoldahanso-tang, Cheongsimyeonja-tang and Taeeumjowi-tang) were applied to investigate the anti-inflammatory activities. In many studies, plant-derived anti-inflammatory efficacies have been investigate for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory activities of 4 herbal formulas on LPS-stimulated RAW 264.7 cells. 2. Methods The productions of nitric oxide (NO), prostaglandin (PG)$E_2$, interleukin(IL)-6 and tumor necrosis factor (TNF)-${\alpha}$ were examined in the presence of the 4 herbal formulas in RAW 264.7 cells. The cells were incubated with LPS 1 ${\mu}g/mL$ and 4 herbal formulas for 18 hrs. The anti-inflammatory activity of 4 herbal formulas were investigate by carrageenin-induced paw edema in rats. The paw volume was measured at 2 and 4 hrs following carrageenininduced paw edema in rats. 3. Results Yanggyeoksanhwa-tang and Cheongsimyeonja-tang showed inhibitory effect on $PGE_2$ production in LPS-stimulated RAW 264.7 cells and a reduction in carrageenin-induced paw edema on rats. Yanggyeoksanhwa-tang showed inhibitory effect on IL-6 in LPS-stimulated RAW 264.7 cells. 4 herbal formulas not affect on NO and TNF-${\alpha}$ inhibition in LPS-stimulated RAW 264.7 cells. 4. Conclusions These results suggested that Yanggyeoksanhwa-tang and Cheongsimyeonja-tang have anti-inflammatory activity.

대황-황금 혼합물이 만성 역류성 식도염에 미치는 효과

이진아,오민혁,신미래,노성수,박해진,Lee, Jin A,Oh, Min Hyuck,Shin, Mi-Rae,Roh, Seong-Soo,Park, Hae-Jin 한국생약학회 2022 생약학회지 Vol.53 No.1

일본의 고령자 지원을 위한 정보통신기술 정책 동향 및 활용

이진아,Lee, Jin Ah 한국정보통신학회 2019 한국정보통신학회논문지 Vol.23 No.11

초고령 사회 일본은 다양한 사회문제 해결 방법 중 하나로 정보통신기술의 활용을 적극적으로 추진하고 있다. 특히 머지않아 초고령 사회에 진입할 우리나라로서는 고령자 지원과 관련한 ICT활용에 대한 일본의 정책 및 현황을 살펴보는 것은 의미가 있을 것이다. 본 연구에서는 문헌조사를 통하여 일본의 고령자 지원관련 ICT정책 및 활용 현황을 살펴보고 우리나라 고령자 지원과 관련하여 다음과 같은 사항을 제안하였다. 고령자 지원관련 현장에서 ICT기술이 실질적으로 활용될 수 있는 기회가 넓혀져야 하며, 일본의 경우처럼 고령자 지원에 있어서 개호와 의료의 연계가 중요하기 때문에 이러한 기관간의 정보연계네트워크 구축을 위한 노력이 필요하다. 또한 다양한 로봇의 개발 및 보급을 통해 개호자와 관련 인력의 서류업무의 간소화 및 개호 부담의 완화를 모색해야 한다. 그리고 ICT활용을 통한 고령자를 위한 정서지지 및 안정을 위한 기술의 보급도 적극 추진되어야 한다. Super aged society, Japan actively uses Information Communication Technology(ICT) as one of solving methods for various social problem. Especially, for Korea where soon will become super aged society, it would be meaningful to examine the current policy trends and utilization of senior support using ICT in Japan. This study explores the policy trends and utilization of senior support using ICT in Japan through literature review, and then proposes some suggestions as follows. Opportunities for practical use of ICT should be widened in the field of senior support, and efforts are needed to build an information linkage network between institutions for senior support because linkage between care sector and medical sector is important for the elderly support. Besides, simplification of paperwork and easing of burden of care providers or workers in the field should be sought by development and dissemination of various robots. Moreover, the spread of technology for emotional support and stability should be actively pursued by using ICT.

부직포형 기체 여과재의 구조와 여과 특성

이진아,주창환,Lee, Jin-Ah,Joo, Chang-Whan 한국섬유공학회 2010 한국섬유공학회지 Vol.47 No.2

Various air-filter media by using meltblown (MB) and spunbond (SB) nonwovens were structurally designed with different laying methods to obtain the relationship between structure and characteristic of air filters. Air permeability, pore size, filter efficiency and pressure drop of the designed filter media were investigated experimentally. The layer sequences of designed media showed significant factor on filter efficiency and pressure drop. The optimum filter media was determined as two layer structural design composed of calendering SB and MB nonwovens. In addition, a model equation to predict the pressure drop and filter efficiency of air filter media based on nonwovens was developed. The calculated values from the equation showed good agreement with experimental ones.

교육후기 - 목장의 미래를 담아오다

이진아,Lee, Jin-A 한국낙농육우협회 2013 낙농·육우 Vol.33 No.2

연료전지용(燃料電池用) 막전극접합체(膜電極接合體)의 막분리(膜分離) 및 염산(鹽酸)에 의한 백금(白金)과 루테늄의 침출(浸出)에 관(關)한 연구(硏究)

이진아,강홍윤,유호진,Lee, Jin-A,Kang, Hong-Yoon,Ryu, Ho-Jin 한국자원리싸이클링학회 2012 資源 리싸이클링 Vol.21 No.3

본 논문에서는 연료전지 막전극접합체에서 막분리 및 염산침출법을 이용하여 백금과 루테늄을 침출하는 연구를 하였다. 증류수, 10 vol.% 부탄올 용액, 15 vol.% 양이온 계면활성제(Koremul-LN-7)를 이용하여 연료전지 막전극접합체의 전해질막과 확산층을 침지법으로 촉매입자의 분산 없이 분리하였다. 그리고 질산 또는 과산화수소를 산화제로 하고 사용하는 염산에 의해 분리된 가스확산층의 촉매에 함유된 백금과 루테늄 금속을 침출하는 연구를 하였다. 과산화수소를 산화제로 사용하였을 때 백금과 루테늄의 침출율이 더 높았으며 최적 조건은 $90^{\circ}C$에서 염산 농도 8 M, 과산화수소 첨가량 5 M, 침출시간 6시간이었다. 이 조건에서 백금의 침출률은 98%, 루테늄의 침출율은 71.5%였다. In this paper, we carried out separation of membrane and leaching of Pt and Ru using hydrochloric acid from MEA(membrane-electrode assembly) of fuel cell. In this method, these were separated from MEA of fuel cell using the distilled water, 10 vol.% butanol solution and 15 vol.% cationic surfactant(Koremul-LN-7) by dipping method without the dispersion of catalyst particles. And the leaching of Pt and Ru containing in the separated carbon paper catalysts has been studied by hydrochloric acid using $HNO_3$ or $H_2O_2$ as a oxidant. The leaching ratio of Pt and Ru were higher when $H_2O_2$ was used as a oxidant and the optimum conditions were obtained in 8M HCl, the amount of $H_2O_2$ 5M and 6 hours of leaching time at $90^{\circ}C$. In this condition, extraction of Pt and Ru were 98% and 71.5%, respectively.

과학기술위성3호 부탑재체 소형영상분광기 미광 해석

이진아,이준호,Lee, Jin Ah,Lee, Jun Ho 한국광학회 2012 한국광학회지 Vol.23 No.4

This paper reports on the stray light analysis results of a compact imaging spectrometer (COMIS) for a microsatellite STSAT-3. COMIS images Earth's surface and atmosphere with ground sampling distances of 27 m at the 18~62 spectral bands (0.4 ~ 1.05 ${\mu}m$) for the nadir looking at an altitude of 700 km. COMIS has an imaging telescope and an imaging spectrometer box into which three electronics PCBs are embedded. The telescope images a $27m{\times}28km$ area of Earth surface onto a slit of dimensions $11.8{\mu}m{\times}12.1mm$. This corresponds to a ground sampling distance of 27 m and a swath width of 28 km for nadir looking posture at an altitude of 700 km. Then the optics relays and disperses the slit image onto the detector thereby producing a monochrome image of the entrance slit formed on each row of detector elements. The spectrum of each point in the row is imaged along a detector column. The optical mounts and housing structures are designed in order to prevent stray light from arriving onto the image and so deteriorating the signal to noise ratio (SNR). The stray light analysis, performed by a non-sequential ray tracing software (LightTools) with three dimensional housing and lens modeling, confirms that the ghost and stray light arriving at the detector plane has the relative intensity of ${\sim}10^{-5}$ and furthermore it locates outside the concerned image size i.e. the field of view of the optics. 과학기술위성3호 부탑재체인 COMIS(Compact Imaging Spectrometer)는 무게 4.25 kg의 소형영상분광기로써 지표면 및 대기과학을 연구할 목적으로 개발되었다. COMIS는 지표면, 대기, 수면으로부터 반사되는 태양 에너지를 고도 700 km에서 가시광 및 근적외선 영역(0.4 ~1.05 ${\mu}m$)에서 해상도 27 m, 관측폭 28 km, 파장 분해능 2 ~ 15 nm를 갖도록 결상 광학계와 분광 광학계로 구성된다. 먼저 지상 $27m{\times}28km$의 해당되는 지표면에서 반사된 빛은 COMIS의 결상 광학계에 의하여 상면에 위치한 $11.8{\mu}m{\times}12.1mm$의 선형 슬릿으로 맺히고, 이후 약 1.1배의 배율을 갖는 분광 광학계의 상면에 $1.4mm{\times}13.3mm$의 크기를 갖는 분광 스펙트럼 영상으로 나타난다. 이 때 부분 반사 및 산란 등에 의한 신호대잡음비(SNR, signal to noise ratio) 저하를 방지하기 위하여 렌즈 및 거울 면에 무반사 및 고반사 코팅이 적용되었고, 내부에는 미광 차단 구조물 등이 설치되었다. 미광 차단 설계의 적정성을 확인하기 위하여 미광 모델 수립과 상용 프로그램을 이용한 미광 해석을 수행하였다. 해석 결과 미광의 세기는 정상 결상 대비 무시할 정도의 값($10^{-5}$)으로 영상에는 실질적인 영향이 없음을 확인하였다.

가미보허탕(加味補虛湯)으로 치료한 산후우울증 1예에 대한 임상보고

이진아,반혜란,조성희,Lee, Jin-A,Ban, Hye-Ran,Cho, Seong-Hee 대한한의학방제학회 2005 大韓韓醫學方劑學會誌 Vol.13 No.1

As woman receive many stress during pregnancy and delivery, they happen to contract to psychopathy like a postpartum depression. Postpartum depression is a serious problem if they are not treated early enough the unhappy seriousness can be resulted. A 32-yeared-old female patient with postpartum depression was taken to Dongshin University oriental medical hospital on April, 28, 2003. We diagnosed this patient as postpartum depression, which originated from and efficiency of vital energy and blood. We treated this postpartum depression patient with herb medicine(Cami-Boheo-tang),acupuncture, moxibustion, and psychical therapy. After the oriental medical treatments, the patient was improved in all complains of the postpartum disease. After this, further study and approach will be needed about the disease of the postpartum depression.

퍼지를 적용한 계약망 프로토콜 기반의 네트워크 보안 모델의 설계 및 시뮬레이션

이진아,조대호,Lee Jin-ah,Cho Tae-ho 한국시뮬레이션학회 2005 한국시뮬레이션학회 논문지 Vol.14 No.1

Attempts to attack hosts in the network have become diverse, due to crackers developments of new creative attacking methods. Under these circumstances the role of intrusion detection system as a security system component gets considerably importance. Therefore, in this paper, we have suggested multiple intrusion detection system based on the contract net protocol which provides the communication among multiple agents. In this architecture, fuzzy rule based system has been applied for agent selection among agents competing for being activated. The simulation models are designed and implemented based on DEVS formalism which is theoretically well grounded means of expressing discrete event simulation models.