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실험연구 : 상복강 대동맥 교차차단 및 재관류 시 Fenoldopam 투여가 허혈성 신 손상에 미치는 영향
유진균 ( Jin Gyun Yoo ),박혜령 ( Hye Ryoung Park ),이용철 ( Yong Cheol Lee ),김진모 ( Jin Mo Kim ),장영호 ( Young Ho Jang ),김애라 ( Ae Ra Kim ),배정인 ( Jung In Bae ),홍지희 ( Ji Hee Hong ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.52 No.2
Background: The overall rate of renal complication after surgery on the suprarenal aorta remains high. In this study, the changes in renal blood flow (RBF), urinary oxygen tension (PuO2), renal vascular resistance (RVR), and urinary volume following fenoldopam administration were investigated in supraceliac aortic cross-clamping and unclamping animal model. Methods: Twelve dogs were divided into two groups; control group (n = 6), fenodopam group (n = 6). After brachial, femoral, and pulmonary arterial catheterization, midline abdominal incision was made. For the aortic cross-clamping the supraceliac aorta was exposed. A doppler flowmeter probe was placed around right renal artery. A ureteral catheter was positioned at the right renal pelvis to measure urine volume and urinary oxygen tension (PuO2). In fenoldopam group, 0.5μg/kg/min of fenoldopam was administered immediately before suprarenal aortic reperfusion. Systemic hemodynamics, renal blood flow, renal vascular resistance, PuO2, and urine volume were compared between two groups. Results: The systemic hemodynamics were not significantly different between the two groups throughout the experiment. After aortic reperfusion, the RVR significantly increased in control group, but the RVR in fenoldopam group remained to baseline level. The urine output, RBF, and PuO2 significantly increased in fenoldopam group compared to control group. BUN and serum creatinine were not different between the two groups. Conclusions: High dose of fenoldopam administration reverse ischemic renal insufficiency after supraceliac aortic cross clamping. (Korean J Anesthesiol 2007; 52: 202~11)
안면에 국한된 병변을 보인 자가면역 수포성 피부질환 5예
안진균(Jin Gyun Ahn),이창우(Chang Woo Lee) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.1
We describe five patiens with autoimmune bullous der matosis who presented cutaneous lesions localized on the face. In these patients iuumunopathologically confirmed diagnoses were penphigus erythematosus, bullous pemphigoid, cicatricial pernphigoid(Brunsting-Perry variant), epidemic lysis bullosa acquisita and bullous systemic lupus erythematosus in each. Except, for the case of pemphigus erythematosus, facelimited cutnious lesions can be seen rarely with these imrnunobullous diseases. We suggest that some external, in malfactors such as UV light and photosensitivity might be regarded as the precipitating factors fo the clinical rnanifestations of those skin lesions, and which should be included in the differential diingosis of vesiculobullous diseases involving the face. (Kor J Dermatol 1995; 33(l): 114-119)
박진균(Jin-Gyun Park),이재영(Jae-Young Lee),김상현(Sang-Hyun Kim),김성락(Sung-Rak Kim) 대한기계학회 2012 大韓機械學會論文集A Vol.36 No.1
본 논문에서는 수직다관절 로봇에 걸리는 중력 토크를 보상하는데 주로 사용되는 스프링 중력보상장치의 최적설계에 대하여 기술하였다. 스트레스, 좌굴, 피로 조건과 같은 스프링 설계에 대한 다수의 비선형 제약 조건을 반영하면서, 동시에 계산 시간을 줄이기 위하여, SQP(Sequential Quadratic Programming)를 적용하였다. 또한 정수해를 가져야 하는 설계 변수를 반영하기 위하여, Continuous Relaxation 방법을 사용하였다. 시뮬레이션을 통하여 설계된 중력보상 장치가 주요 작업 영역에 서 추가의 무게 증가 없이 중력 보상 성능이 효과적으로 높아짐을 입증하였다. In this paper, the optimal design of a spring-type gravity compensation system for an articulated robot is presented. Sequential quadratic programming (SQP) is adopted to resolve various nonlinear constraints in spring design such as stress, buckling, and fatigue constraints, and to reduce computation time. In addition, continuous relaxation method is used to explain the integer-valued design variables. The simulation results show that the gravity compensation system designed by proposed method improves the performance effectively without additional weight gain in the main workspace.
안진균 ( Jin Gyun Ahn ),이창우 ( Chang Woo Lee ) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.4
Background : In autoimmune bullous dermatoses, such as pemphigus and bullous pemphigoid, variations in the expression of the antigen in different body locations are recognized. Objective : The degree of expession of epidermolysis bullosa acquisita (EBA) antigen in different sites on the body surface was estimated from the highest dilution factor of EBA sera that gave a positive reaction at a site by indirect immunofluorescence (IF). Methods : Two sera, obtained from EBA patients with inflammatory and mechanobullous skin lesions, having antihody titers of 160 against the dermal component of the NaCl split skin, were used by indirect IF techniques with 20 specimens (2 from each of 10 locations) of normal human skin from different sites. These 20 skin samples were obtained from 10 healthy adults (1-3 from each individual). Results : The greatest expression of the antigen was in the skin taken from the upper back with the titer of 160. EBA antigen was least recognized in skin specimens from the inner thigh and calf. Skin from the scalp, abdomen, and anterior chest and others demonstrated intermediate degrees of expression. Conclusion : There was some moderate degree of variation in the expression of EBA antigens in skin samples obtained from different locations on the body. It seems however that there is not any positive correlation between the degree of expression of EBA antigen in each location and predilection sites (possibly the trunk) of clinical lesions in EBA. (Kor J Dermatol 1995;33(4): 611-615)
51.84Mbps VDSL QAM 수신기를 위한 통과대역 디지털 심볼 클록 복원방식
이재호,김재원,정항근,정진균,Lee, Jae-Ho,Kim, Jae-Won,Jeong, Hang-Geun,Jeong, Jin-Gyun 대한전자공학회 2000 電子工學會論文誌-SC (System and control) Vol.37 No.2
본 논문에서는 51.84Mbps의 전송 속도를 갖고, 16-QAM 변조방식을 사용하는 VDSL(고속 디지털 가입자 루프) 시스템에서, 전송 신호 주파수 스펙트럼의 밴드-에지 성분을 최대화함으로써 심볼 클록(12.96㎒)을 복원하는 방식에 대해 논의한다〔1〕. 디지털 방식의 PLL에서 여러 가지 특성들이 조사되었으며, NCO(Numerically Controlled Oscillator)에서 사용하는 룩-업 테이블의 효율적인 설계 방식을 제시하였다. In this paper, we discuss a symbol clock extraction scheme based on maximizing the band-edge component of the transmitted signal frequency spectrum for applications to 51.84Mbps VDSL system which uses a 16-QAM. The major characteristics of the digital PLL are examined. In addition, we suggest an efficient design method of a sinusoidal look-up table which is used for NCO.
CIM(Combined Integer Mapping)을 이용한 OFDM 송신기의 IFFT 메모리 감소
이재경(Jae-Kyung Lee),장인걸(In-Gul Jang),정진균(Jin-Gyun Chung),이철동(Chul-Dong Lee) 大韓電子工學會 2010 電子工學會論文誌-TC (Telecommunications) Vol.47 No.10
FFT(Fast Fourier Transform)는 IEEE 802.22와 같은 여러 무선표준에서 사용되는 OFDM 시스템의 주요 블록 중 하나이다. FFT의 전력소모 감소, 면적감소, 고속동작을 위해 새로운 FFT 아키텍처 개발, twiddle factor 곱셈을 위한 곱셈기의 수나 면적감소, 제어회로의 단순화 등에 초점을 둔 FFT 프로세서의 구현에 관한 연구가 지속적으로 진행되어왔다. FFT의 입력포인트 수 N이 증가함에 따라 log2N 개의 각 FFT 스테이지 구현에 사용되는 시프트레지스터(또는, 메모리)가 차지하는 비중이 전체 FFT회로의 70%이상이 되며 이러한 메모리들은 FFT의 처음 두 스테이지에 집중되어 두 스테이지의 메모리가 전체 메모리의 75%를 차지한다. 본 논문에서는 OFDM 송신부의 IFFT(Inverse Fast Fourier Transform)에서 요구되는 메모리 사이즈를 감소시키기 위해 입력변조신호, 파일럿(pilot)신호, 널(null) 신호의 mapping을 IFFT와 결합하는 새로운 기법을 제안한다. Cognitive radio 시스템에 적용하기 위한 2048포인트 IFFT를 제안한 방법으로 설계하고 메모리가 차지하는 면적에서 기존의 방법과 비교하여 38.5 %이상의 이득을 가짐을 보인다. FFT(Fast Fourier Transform) processor is one of the key components in the implementation of OFDM systems for many wireless standards such as IEEE 802.22. To improve the performances of FFT processors, various studies have been carried out to reduce the complexities of multipliers, memory interface, control schemes and so on. While the number of FFT stages increases logarithmically (log2N) as the FFT point-size (N) increases, the number of required registers (or, memories) increases linearly. In large point-size FFT designs, the registers occupy more than 70% of the chip area. In this paper, to reduce the memory size of IFFT for OFDM transmitters, we propose a new IFFT design method based on a combined mapping of modulated data, pilot and null signals. The proposed method focuses on reducing the sizes of the registers in the first two stages of the IFFT architectures since the first two stages require 75% of the total registers. By simulations of 2048-point IFFT design for cognitive radio systems, it is shown that the proposed IFFT design method achieves more than 38.5% area reduction compared with previous IFFT designs.