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RISS 인기검색어
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- 저자 : 이중엽 ( Joong Yub Lee ) (검색결과 2 건)
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이준호 ( Joon Ho Lee ),진상윤 ( Sang Yun Jin ),최윤석 ( Yun Seok Choi ),권혁부 ( Hyok Bu Kwon ),이승호 ( Seung Ho Lee ),이중엽 ( Joong Yub Lee ),박병주 ( Byung Joo Park ),이애영 ( Ai Young Lee ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.2
Background: Spa has been applied for the alleviation of atopic dermatitis (AD), but there have been few studies on the efficacy and safety of hot spring sea water therapy. Objective: This study aimed to clarify the conditions which have adequate efficacy and safety of hot spring sea water therapy for the treatment of AD. Method: Twenty-eight patients with AD who had mild to moderate symptoms were enrolled and divided into 14 groups according to bathing frequencies, temperatures, durations, and kinds of water. Bathing frequency was 2, 3 or 7 times a week. Temperature was 37˚C or 40˚C, and duration was 15 or 30 minutes. Twelve groups took a bath in hot spring sea water obtained from an island in Korea, 1 group took a bath in salt water and 1 took a bath in tap water. We assessed o-SCORAD index at baseline and every week for 4 weeks. In addition, colony counts of S. aureus were evaluated at baseline and at the last visit. Result: The 3 times-a-week/37˚C/15 minute and twice-a-week/37˚C/30 minute groups showed the largest and continuous decline in o-SCORAD index. The index was also slightly decreased in the salt and tap water groups. The colony counts of S. aureus did not show significant changes after bathing. Conclusion: This pilot study shows the possibility that hot spring sea water therapy might be an efficacious and safe treatment option for treating AD. However, the precise mechanism should be elucidated through further studies. (Korean J Asthma Allergy Clin Immunol 2011;31:124-130)
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양성전립선비대증 증상 조절을 위해 투여되는 알파차단제의 골절위헙
이중엽,최남경,정선영,김예지,성종미,오승준,박병주,Lee, Joong-Yub,Choi, Nam-Kyoung,Jung, Sun-Young,Kim, Ye-Jee,Seong, Jong-Mi,Oh, Seung-June,Park, Byung-Joo 대한예방의학회 2009 예방의학회지 Vol.42 No.3
Objectives : We evaluated the risk of fracture associated with hypotension-related adverse drug reaction caused by taking alpha blockers to treat benign prostatic hyperplasia (BPH). Methods : We used the Health Insurance Review and Assessment Service database from January 1st 2005 to June 30th 2006 for this study. The male patients with BPH and who had a prescription for alpha blockers following any fractures were defined as the cases. We set the 20 day long hazard period prior to the index date and the four control periods whose lengths were same with hazard period. After 1:4 matching of the hazard and control periods, conditional logistic regression was used to calculate the odds ratios for the risk of fractures as related to the alpha blocker exposure. Results : Doxazosin and tamsulosin showed the increased risk of fractures, whereas terazosin did not. After stratification using the defined daily doses, a protective effect was shown for the patients who took terazosin at the doses lower than 0.4 DDD and the hazardous effect at the doses higher than or equal to 0.4 DDD. There was no significant difference for the risk of patients taking tamsulosin at the doses higher than 1.0 DDD but there was a statistically significant increase in the risk at the doses higher than or equal to 1.0 DDD. Conclusions : Alpha blockers for BPH may increase the risk of fracture in elderly patients who have comorbidities and take the concomitant medications. Alpha blockers need to be prescribed with caution, although some have high prostate specificity.
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