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RISS 인기검색어
- 검색키워드
- 저자 : 이조희(Jo-Hee Lee) (검색결과 4 건)
- 무료
- 기관 내 무료
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황의완(Wei Wan Whang),김종우(Jong Woo Kim),이조희(Jo Hee Lee),엄효진(Hyo Jin Eom),이승기(Seung Gi Lee) 대한한방신경정신과학회 1996 동의신경정신과학회지 Vol.7 No.1
N/A 1. Out of 21 examples on a clinical base Alzheimer type dementia were 8 examples(38%), 11 vascular types(52%), 1 Alzheimer and vascular mixed type and rest 1 was secondary dementia type(NPH). 2. Between the gendes, there were 5 males and 3 females for Alzheimer types, 6 males and 5 females for the vascular types, 1 male for Alzhrimer and vascular mixed type, and 1 frmale for secondary dementia type(NPH). 3. For the degrees of Alzheimer type dementia there were 2 mild dementia, 4 moderate dementia, and 2 severe dementia. 4. Among the Alzheimer types 2 mild dementia were almost recovered back to normal in approximately 2 months, 2of 4 moderate dementia became significantly better in approximately 2 months and recovered to almost normal state in 3 to 5 months. The rest 2 have been under treatment for 3 months, but showed a little improvement. Out of 2 severe dementia examples, one showed a little improvement even if it has been under treatment over 2 years. The other exampe did not show any improvement, but dementia did not proceed any more. 5. Among the 11 vascular examples, 7 recovered in 2 to 3 months, 1 in 5 months, 2 recovered in a year, and the treatment was stopped arbitrary for the last one. 6 In the case of Alzheimer and vascular mixed type dementia, even the moderate dementia did not show any apparent result in 6 months. 7. For NPHI (Normal Pressure Hydrocephalus), there was an improvement on dementia in 2 months after the treatment, but gait disturbance and urinary incontinence did not show any noticeable difference. As a conclusion, almost all the Alzheimer and vascular type patients recovered, but the treatment periods varied depending on the types of the dementia and the degree of seriousness, especially in the case of the severe Alzheimer patients, the treatment oniy suppression the progression of the dementia. The most important aspect from clinical point of view was even if almost all the patients were almost completely cired, they need to keep being cured for a long period of time. The methol with respect to Four Constitutions is thought of the most desirable.
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麝香蘇合元이 흰쥐의 방사형 미로 학습과 기억에 미치는 영향
이조희,김종우,황의완,김현택,이홍재 대한한방신경정신과학회 1998 동의신경정신과학회지 Vol.9 No.2
Purpose: This study was conducted to find out the effects od Sahyangsohapwon on learning and memory of rats. Method: In the experiment, rats were divided two groups. One was control group which was adminstered Sahyangsohapwon and the other was sample group administered placebo. Numbers of each group were 13 rats. 8-arm radial maze task was used in it, and working memory test and retention(reference memory) test were done. Before the beginning of the test, the rats were deprived of water for 24hrs. In the frist test, each of eight arm was baited with water and a rat was permitted to remain on the maze until all eight arms were entered. A working memory error was defined as revisit of any previously entered arm. When a rat made an error not exceeding one time in consecutive 3 days-performance, it was regarded as learning criteria and the test was ended. The reference memory was evaluated with total days which it took rats to pass the learning crtirtia. The second test was performed after 24 hours when the first test was over. When a rat entered 4 arms, the entrance of arm was cut off during 30 seconds. Here the number if errors which was produced during a rat find remaining 4 tracks was regarded as the index of memory. This experiment compared the number of error at the control group with that of the sample group. Result: 1. In the first test, it was shown that the sample group took 7.69±1.11 days and the control group 9.31±1.97 days to pass the learning criteria. There was statistically significant reference mernory development at the sample group. 2. In the second test, the frequency of errors made by the two groups were 0.92±1.32 times for the control group and 1.23±1.59 times for the Sahyangsohapwon group. There was no difference between the groups in frequency of errors. Conclusion: It is suggested that Sahyangsohapwon has effects on the improvement of learning and memory.
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