체외충격파쇄석술을 이용한 만성 췌장염 환자의 췌관결석의 분쇄: CT를 이용한 치료 효과의 분석

이용석,이문규,Lee, Yong-Suk,Lee, Moon-Gyu 대한영상의학회 2003 대한영상의학회지 Vol.48 No.3

목적: 만성 췌장염 환자에서 췌관결석에 대한 체외충격파쇄석술의 치료 효과를 CT를 이용하여 알아보고자 하였다. 대상과 방법:내시경적 중재술로 췌관결석 제거에 실패한 10명과 Whipple 수술을 받아 내시경을 시행할 수 없었던 1명을 포함한 총 11명의 만성 췌장염 환자에게 전기수압쇄석 방식의 체외충격파쇄석술이 시행되었다. 쇄석술 시행 전후의 CT 영상을 두 명의 방사선과 의사가 분석하였는데, 대상 결석의 장경과 단경을 측정한 후 면적을 비교하여 분쇄 정도를 5단계로 분류하였고 췌장 체부에서의 주췌관의 직경을 측정하여 비교하였다. 결과: 모든 환자에서 체외충격파쇄석술을 이용하여 췌관결석을 분쇄할 수 있었는데,시술 전과 비교하여 75%이상의 면적이 남아 있는 1군은 2명, 51-75%가 남아있는 2군은 1명, 26-50%가 남아있는 3군은 4명, 25%이하로 남아있는 4군은 2명, 결석이 완전히 제거된 5군은 2명이었다. 결석의 평균 면적은 175 $\textrm{mm}^2$에서 쇄석술 시행 후 69$\textrm{mm}^2$으로 감소하였으며 (p<0.05),11명 중 8명 (73%)에서 50%이상 면적이 감소하였다. 주췌관의 평균 직경은 7.36mm에서 4.81 mm로 감소하였다 (p<0.05). 모든 환자에서 심한 부작용이나 합병증은 나타나지 않았으며, 시술 후 만성 췌장염의 증상이 모든 환자들에서 호전 되었다. 추적검사에서 3명의 환자에서 결석이 재발되었다. 결론: 체외충격파쇄석술은 만성 췌장염 환자의 췌관결석을 안전하게 분쇄할 수 있으므로 내시경으로 제거가 실패한 경우에 사용을 고려해야 하며, CT는 체외충격파쇄석술의 치료 효과를 비침습적이며 정확하게 평가하는데 유용하게 사용될 수 있을 것이다. Purpose: To demonstrate by CT scanning the effect of extracorporeal shock wave lithotripsy (ESWL) on pancreatic duct stones in patients with chronic pancreatitis. Materials and Methods: Pancreatic duct stones in 11 patients with chronic pancreatitis were subject to ESWL using an electrohydraulic lithotripter. Endoscopic stone removal using a basket had failed in ten patients, and in one, endoscopy was impossible due to a previous Whipple's operation. CT scans obtained before and after ESWL were evaluated by two radiologists: the longest and shortest diameters of the target stone were measured, and according to the degree of fragmentation, determined by comparing the area of the stone before and after ESWL, a grade (1-5) was assigned. In each case, the pre- and post- treatment diameter of the main pancreatic duct, measured at the pancreatic body, was also compared. Results: Disintegration of the target stone was achieved in all patients: grade 1 (over 75% of the area remained, compared with that of the initial stone) was assigned in two patients; grade 2 (51-75% of the original area) in one; grade 3 (26-50%) in four; grade 4 (under 25%) in two; and grade 5 (complete clearance of the target stone) in two. The mean area decreased from 175 ㎟ to 69 ㎟ after ESWL (p<0.05); a decrease of more than 50% was observed in eight patients (73%). The mean diameter of the main pancreatic duct decreased from 7.36 to 4.81 mm (p<0.05). No severe adverse effects or complications were noted, and all patients showed clinical improvement. Follow-up studies indicated that pancreatic duct stones recurred in three patients. Conclusion: ESWL can cause the fragmentation of pancreatic duct stones without significant complications, and should be considered where endoscopic stone removal has failed. CT is a suitable non-invasive and accurate tool for evaluating the therapeutic results of ESWL.

반원상 연골판 손상에서의 관절선 압통의 해석

이용석,정영복,최성우,황준성,김만경,이종석,서동현,Lee, Yong-Seuk,Jung, Young-Bok,Choi, Sung-Woo,Hwang, Joon-Sung,Kim, Man-Kyung,Lee, Jong-Suk,Suh, Dong-Hyun 대한정형외과스포츠의학회 2006 대한정형외과스포츠의학회지 Vol.5 No.2

목적: 슬관절 손상의 많은 빈도를 차지하고, 가장 흔하게 수술의 원인이 되는 반월상 연골판 손상을 외래에서 쉽게 일차적으로 검사하는 관절선 압통의 유용성을 알아보고자 하였다. 대상 및 방법: 2005년 5월에서 2006년 6월까지 군병원에서 동일한 시술자에게서 반월상 연골판 손상이 의심되어 수술을 시행한 76명의 환자를 대상으로 관절선 압통(joint line tenderness)에 대한 민감도, 특이도, 정확도, 양성 예측율, 음성 예측율 등을 분석하였다. 결과: 관절선 압통의 민감도, 특이도, 정확도, 양성 예측을, 음성 예측율은 순서대로 78.8%, 32.6%, 52.6%, 47.3%, 66.7%로 나타났으며 외측과 내측 및 불안정성을 동반한 환자를 대상으로 동일하게 분석하여도 상기 결과와 비슷하게 높지 않은 결과를 나타내었다. 결론: 관절선 압통 단일 검사는 외래에서 손쉽게 행해지는 간편한 검사이나, 그 단독 검사로서는 유용성이 떨어지는 것으로 보인다. 그러므로, 여러가지 이학적 검사를 병행 시행하는 것이 좀 더 높은 진단율을 나타낼 것으로 보이고, 필요시에는 자기공명영상(MRI)이나 진단적 관절경 검사도 필요할 것으로 보인다. Purpose: Meniscal injuries are very common sports problems and indications for knee surgery. We analyzed the effectiveness of joint line tenderness retrospectively. Materials and Methods: From May 2005 to June 2006, 76 knees which were diagnosed meniscal injury and performed arthroscopic surgery by same surgeon at military hospital were included. We analyzed sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of joint line tenderness in meniscal diagnosis. Results: The joint line tenderness gave such results (78.8%, 32.6%, 52.6%, 47.3%, 66.7% for sensitivity, specificity, accuracy, positive predictive value, negative predictive value respectively). We got similar results in analyses with medial meniscal lesion, lateral meniscal lesion, and combined instability patients. Conclusion: The joint line tenderness is a easy and comfortable maneuver but, it's effectiveness is low when it is used lonely The composite examinations including MRI and diagnostic arthroscopy for meniscal injuries of the knee perform much better than joint line tenderness alone.

Bacillus subtilusHR-1019와 N-Acetyl-thioproline으로 제조한 미생물처리제, BIOACTIVE에 의한 상추의 생장 촉진

Yong-Suk Lee(이용석),Dong-Ju Park(박동주),Jae Hoon Kim(김재훈),Hyeong Seok Kim(김형석),Soo Yeol Chung(정수열),Yong-Lark Choi(최용락) 한국생명과학회 2013 생명과학회지 Vol.23 No.1

L-Cysteine에서 유도된 아미노산인 ATCA와 불용성 인산 가용화능을 가진 균주를 이용하여 미생물처리제 BIOACTIVE를 제조하고 안정성을 확인 하였다. 제조한 미생물처리제를 미생물 비료로 적용하고자 3회 관주 처리한 다음 상추모종의 생장촉진 효과를 조사하는 실험을 수행하였다. 그 결과로 처리한 시험 구에서 상추의 생육은 엽수, 엽장 및 엽중에서 최대 128%, 122% 및 153% 정도로 증가하였다. 처리 간에는 기준량(1,000배 희석) 처리> 반 량(500배 희석) 처리> 배 량(2,000배 희석) 처리 순으로 나타났다. 공시 BIOACTIVE의 처리가 토양 중의 유효인산 및 식물체내의 인산함량을 최대 118% 및 132% 정도 증가 시키는 경향이었다. BIOACTIVE제제를 처리했을 때 N, P, K 3요소를 관행으로 처리와 비슷한 생육 효과가 있는 것으로 보아 복합비료의 사용량을 줄여, 재배가 충분히 가능하리라 생각되며, 상추의 생육 및 비해 조사를 한 결과 본 관주 처리에서는 생육장해 및 비해는 없었다. A biofertilizer, BIOACTIVE, was manufactured by N-acetyl-thioproline (ATCA) and mineral phosphate solubilizing bacteria. The growth promoting effect of the biofertilizer on lettuce was evaluated under three different pot conditions, and its stability was assessed in the field. According to the results of the pot experiments, plant growth was improved compared with that of control: 128%, 122%, and 153% for the leaf number, leaf length, and leaf mass, respectively. Applying the manufactured biofertilizer increased the concentration of phosphate: 118% and 132% in the cultivation soil and plant cells, respectively. These show that BIOACTIVE may have potential as an effective biofertilizer in agriculture.

System Dynamics를 이용한 원자력발전의 기술가치 평가

이용석 ( Yong Suk Lee ) 한국시스템다이내믹스학회 2006 한국시스템다이내믹스 연구 Vol.7 No.2

Nuclear technology made a great contribution to the national economy and society by localization of nuclear power plant design, and by stabilization of electricity price, etc. It is very important to conduct the retrospective analysis for the nuclear technology contribution to the national economy and society, but it is more important to conduct prospective analysis for the nuclear technology contribution. The term "technology value" is often used in the prospective analysis to value the result of technology development. There are various definitions of technology value, but generally it means the increment of future revenue or the reduction of future cost by technology development. These technology valuation methods are widely used in various fields (information technology or energy technology, etc). The main objective of this research is to develop valuation methodology that represents unique characteristics of nuclear power technology. The valuation methodology that incorporates market share changes of generation technologies was developed. The technology valuation model which consists of five modules (electricity demand forecast module, technology development module, market share module, electricity generation module, total cost module) to incorporate market share changes of generation technologies was developed. The nuclear power technology value assessed by this technology valuation model was 3 times more than the value assessed by the conventional method. So it was confirmed that it is very important to incorporates market share changes of generation technologies. The valuation results of nuclear power technology in this study can be used as policy data for ensuring the benefits of nuclear power R&D (Research and Development) investment.

광학 및 레이더 위성영상으로부터 인공신경망을 이용한 공주시 산림의 층위구조 분류

이용석 ( Yong-suk Lee ),백원경 ( Won-kyung Baek ),정형섭 ( Hyung-sup Jung ) 대한원격탐사학회 2019 大韓遠隔探査學會誌 Vol.35 No.3

기존의 식생정보는 대부분 5년 주기로 구축되어 최신성이 결여 되어있다. 식생의 조사는 사진측량과 사람의 현지조사로 이루어지며, 많은 시간과 비용을 소모하게 된다. 식생의 정보 중 식생층위구조에 대한 정보는 산림의 다양성과 환경을 평가하는 중요한 요소이다. 식생의 내부구조인 층위구조는 필수적 정보이지만, 일반적인 사진측량과 사람의 조사로는 한계점이 존재하게 된다. 본 연구에서는 KOMPSAT-3/3A/5 위성영상으로부터 제작된 지수맵과 Texture맵, DSM(Digital Surface Model)과 DTM(Digital Terrain Model)의 차분으로 생성한 canopy정보를 Input layer로 층위자료를 인공신경망(Artificial Neural Network; ANN)을 이용하여 분류하였다. 단층과 다층의 산림의 층위 구조를 분류하여 최종분류결과 81.59% 확인하였다. Since the forest type map in Korea has been mostly constructed every five years, the forest information from the map lacks up-to-date information. Forest research has been carried out by aerial photogrammetry and field surveys, and hence it took a lot of times and money. The vertical structure of forests is an important factor in evaluating forest diversity and environment. The vertical structure is essential information, but the observation of the vertical structure is not easy because the vertical structure indicates the internal structure of forests. In this study, the index map and texture map produced from KOMPSAT-3/3A/5 satellite images and the canopy information generated by the difference between DSM (Digital Surface Model) and DTM (Digital Terrain Model) were classified using the artificial neural network. The vertical structure of forests of single and multi-layer forests was classified to identify 81.59% of the final classification result.

자동차용 공조기의 부분부하 운전특성에 관한 연구

이용석(Yong-suk Lee),김종우(Jong Woo Kim),박윤철(Youn Cheol Park) 대한설비공학회 2011 대한설비공학회 학술발표대회논문집 Vol.2011 No.7

In this study, cycle test was conducted for the mobile air conditioner at different test conditions. The experiment apparatus was designed and constructed to simulate actual air conditioning system in the compact car which will be available in the market. And the optimum charge test was performed and cycle test with variaiton of on time ratio of the compressor was conducted. Cycle performance during the fan of the evaporator operation was given as results.

회전하는 원형 실린더 주위의 층류 유동장에 관한 수치적 연구

이용석(Yong-Suk Lee),윤현식(Hyun-Sik Yoon),두정훈(Jeong-Hoon Doo),하만영(Man-Yeong Ha) 대한기계학회 2009 大韓機械學會論文集B Vol.33 No.11

The present study numerically investigates three-dimensional laminar flow past a rotating circular cylinder placed in a uniform stream. For the purpose of a careful analysis of the modification of flow by the effect of the rotation on the flow, numerical simulations are performed at a various range of rotational coefficients (0≤α≤2.5) at one Reynolds number of 300. As α increases, flow becomes stabilized and finally a steady state beyond the critical rotational coefficient. The 3D (three dimensional) wake mode of the stationary cylinder defined at this Reynolds number has been disorganized according to α, which were observed by the visualization of 3D vortical structures. The variation of the Strouhal number is very weak when the wake pattern is changed according to the rotational coefficient. As α increases, the lift increases, whereas the drag decreases.

3대에 걸쳐 발생한 산호상 백내장

이용석(Yong Suk Lee),최갑희(Kap Hee Choi) 대한안과학회 1983 대한안과학회지 Vol.24 No.3

유전성 맥관부종

이용석(Yong Suk Lee),정진호(Jin Ho Chung),조광현(Kwang Hyun Cho),윤재일(Jai Il Youn) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.1

We report a case of hereditary angioedema in a 48-year old femal patient. She expericenced facial edema and dyspnea 5 to 6 times for a year. Similar episodes developed on some members of her family, especially her sisters and father. We examined her and h

트렌드 지수를 반영한 블로그 랭킹 알고리즘

이용석(Yong-Suk Lee),김형중(Hyoung Joong Kim) 한국디지털콘텐츠학회 2017 한국디지털콘텐츠학회논문지 Vol.18 No.3