진동수 목적함수를 이용한 텐세그리티 시스템의 형상탐색기법

이승혜,이재홍,강주원,Lee, Seung Hye,Lee, Jae Hong,Kang, Joo Won 한국강구조학회 2016 韓國鋼構造學會 論文集 Vol.28 No.5

In this study, a form-finding method of tensegrity systems by using the force density method combined with the stiffness matrix method was presented. Numerous studies have been made on form-finding methods of the tensegrity systems. However, these methods are limited in the tensegrity systems with multiple null space of the equilibrium matrix. The proposed method can uniquely define a single integral feasible set of force densities for the structures. In order to draw maximum natural frequency that can lead a maximum stiffness of the tensegrity systems, a constrained maximization problem is formulated in the genetic algorithm. Several numerical examples are presented to prove dfficiency in searching for self-equilibrium congifurations of tensegrity systems with multiple self-stress states. A good performance of the proposed method has been shown in the results. 본 연구에서는 내력밀도법과 강성행렬법을 결합한 방법을 사용한 텐세그리티 시스템의 형상탐색기법을 제안하였다. 텐세그리티 시스템의 형상탐색 기법에 대한 연구는 많은 연구자들에 의해 계속되어왔으나 그 기법들은 복수의 자기응력 상태를 갖는 시스템의 경우 한계가 있다. 제안 기법을 사용하면 복수의 자기응력상태를 갖는 텐세그리티 구조물에 대한 최적의 내력밀도 값을 결정할 수 있다. 텐세그리티 시스템의 최대 강성 값을 유도하기 위해 구조물의 고유진동수 값을 최대로 이끌어 내는 목적함수를 설정한 유전 알고리즘을 사용하였다. 다수의 평형상태를 갖는 텐세그리티 시스템의 자기평형 형태를 얻을 수 있는 본 기법에 대한 효율성을 입증하기 위해 수치해석 예제를 수행하였으며 이를 통해 만족하는 결과 값을 얻을 수 있었다.

역 최적화 방법을 이용한 트러스 구조물의 손상탐지

이승혜,이재홍,Lee, Seung Hye,Lee, Jae Hong 한국강구조학회 2013 韓國鋼構造學會 論文集 Vol.25 No.4

손상을 입은 구조물은 고유 특성 값이 변한다. 본 연구는 건전상태의 고유 특성 값과 손상상태의 특성 값 차이를 사용하여 손상 탐지 하는 것을 목적으로 한다. 두 대비되는 모델간의 특성 차이를 극대화 시키는 조건을 찾는 역 최적화 기법이 사용되었다. 본 논문은 손상탐지 알고리즘 구축의 전 단계로 건전상태와 손상상태의 트러스 구조물 변형에너지의 차이를 극대화 할 수 있는 하중조건을 찾는 알고리즘을 개발하였다. 트러스 구조물에 대한 예제는 제안 기법의 정확성과 효과를 입증한다. Damaged structures change the value of natural properties. The purpose of this study is to detect damage using the difference of natural properties between the healthy state and the damaged state. Anti-optimization method is used to find the conditions that maximize the difference in characteristics between the two contrasting models. In this paper, a algorithm for finding the loading conditions which can maximize the difference of strain energy between the healthy state and the damaged state of truss structures is developed. Numerical examples show that the proposed method is accurate and efficient for truss structures.

건축물 3D 프린팅 기술

이승혜,김남일,이재홍,Lee, Seung-Hye,Kim, Nam-Il,Lee, Jae-Hong 한국전산구조공학회 2015 전산구조공학 Vol.28 No.3

리모델링 부재 적용을 위한 텐세그리티 유닛 설계기법

이승혜,이재홍,정성원,Lee, Seung-Hye,Lee, Jaehong,Jung, Sung-Won 한국공간구조학회 2017 한국공간구조학회지 Vol.17 No.4

In this study, an advanced form-finding method of tensegrity unit modules is presented to apply on renovation building. Here a fitness function of maximum natural frequency which can lead to a maximum stiffness status was used for a genetic algorithm. To apply the lightweight pin-jointed structure to the renovation project is more economical over to build new structures. In this paper, two types of tensegrity unit are presented to build expanded structures, and their force densities are shown using the proposed form-finding method. The expanded structures which may influence renovation projects are presented by using the tensegrity units.

도상, 기능, 맥락: 중국 승가(僧伽) 이미지를 보는 또 하나의 시각

이승혜 ( Seung Hye Lee ) 미술사와 시각문화학회 2013 미술사와 시각문화 Vol.12 No.-

Identifying various divinities in Buddhist pantheon through iconographic or typological analysis has been a major concern for scholars of Buddhist art. This line of inquiry is more often than not devoted to sculptures and paintings, which are deemed ``aesthetic`` and thought to function as cult images. Such focus inevitably reduces subjects of research to art objects made by human hands, while leaving significant constituents of religious visual culture such as lacquered bodies and apparitional visions understudied. This paper attempts to reconsider and complement narrowly defined iconographic analysis through a case study of the cult of Sengqie(僧伽, 617-710) and his imagery in Chinese Buddhist art during the Tang and Song periods. Extant historical sources relate that the monk Sengqie, of Central Asian origin, came to China in the midseventh century and founded a monastery dedicated to the Puzhao Buddha in Sizhou, a region located at nodal points of waterway transportation. Diverse dimensions of the Sengqie cult have received considerable scholarly attention both in Western and East Asian academia since the 1950s. On one hand, the Sengqie cult has been treated largely as the epitome of the Song Buddhist rubrics of “popular cult” and/or “localization,” an area pioneered by Makita Tairyo - and expanded upon by other scholars. The shared scholarly narrative highlights how in the cult of Sengqie the focus shifts from the veneration of Sengqie`s conduct and teachings to devotion to his mummy, and, thus, how a foreign charismatic monk became domesticated and metamorphosed into a divine protagonist of immediate salvific efficacy. On the other hand, images of Sengqie have been subject to intense art historical analyses that aim to establish iconographic convention in artistic representations of Sengqie, to identify statues showing similar visual traits but lacking inscriptional evidence as representations of the monk, and to classify extant images into several formal types. This study shifts the focus from the iconographic consistency and clarity shown in extant Sengqie images to the reason why these images look the way they do by shedding new light on the fundamental aspect of the Sengqie cult and imagery. It suggests that Sengqie`s body-turned-icon enshrined inside his pagoda at Sizhou functioned as the model of his representations and as such, it signals the ``iconization of death,`` a cultural phenomenon that emerged from the eighth century in Chinese religious visual culture. By incorporating Sengqie`s lacquered body and apparitions into art historical analysis, this study illuminates hitherto neglected but fundamentally significant aspects of the Sengqie imagery. It further demonstrates that contextual and functional analysis complement purely iconographic study.

난소적출 마우스에서 지백지황탕 열수 추출물의 갱년기 장애 개선 효과 평가

이승혜 ( Seung-hye Lee ),김동철 ( Dong-chul Kim ) 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.2

목 적: 본 연구에서는 지백지황탕 열수추출물(수율=19.76%)의 갱년기 장애 개선 효과를 확인하기 위해 난소적출(Ovariectomy, OVX) 마우스 모델을 이용하여 estrogen 유사 효과, 항비만 효과, 고지혈증 억제 효과, 지방간에 대한 보호 효과 및 골다공증 억제 효과의 5가지 생리활성 효과로 구분하여 평가하였다. 방 법: 본 연구에서는 지백지황탕의 갱년기 장애 개선 효과를 평가하기 위해 사람의 다양한 갱년기 장애와 유사한 증상을 나타내는 난소적출 마우스모델을 활용하였다. 총 6개의 실험군에서 각 8마리의 마우스를 사용하여 위수술 sham 대조군, OVX 대조군, Estradiol 대조 약물군, 지백지황탕 500, 250, 125 mg/kg 투약 실험군으로 나누어 실험하였다. OVX 수술 28일 후부터 지백지황탕 추출물을 각각 500, 250 and 125 mg/kg으로 매일 1 회씩 84일 동안 경구투여하고, 17β-estradiol 0.03 μg/head/day 피하 투여군과 비교 하여 estrogen 유사 효과, 항비만 효과, 고지혈증 억제 효과, 지방간에 대한 보호 효과 및 골다공증 억제효과로 구분하여 평가 하였다. 본 실험결과는 17β-estradiol 0.03 μg/head/day 피하 투여 마우스에서의 결과와 비교 평가 하였다. 결 과: 본 실험의 결과, OVX 대조군에서는 위수술 매체 대조군에 비해 현저한 체중 및 증체량, 체지방 및 복부 축적 지방량, 복부 축적 지방 중량, 혈청 중 AST, ALT, TC, LDL, TG 및 osteocalcin 함량의 증가가 자궁, 간 및 대퇴골 중량, 혈중 bALP 및 estradiol 함량, 평균 total body 골밀도 및 대퇴골 골밀도의 감소와 함께 인정되었으며, 현저한 복부 축적 지방 두께의 증가 및 지방세포의 비대, 간의 지방병증, 자궁의 불용성 위축, 대퇴골의 골량 감소 소견이 각각 인정되었다. 한편 이러한 OVX에 의해 유발된 estrogen 결핍성 폐경기 관련 갱년기 장애 소견이 지백지황탕 추출물 500, 250 및 125 mg/kg의 84일에 걸친 연속 투여에 의해 투여 용량 의존적으로 현저히 억제되었으며, 특히 지백지황탕 500 mg/kg은 estradiol 0.03 μg/head/day 피하투여군과 유사한 갱년기 장애 개선 효과를 OVX 마우스에서 나타내었다. 결 론: 이상의 결과에서, 지백지황탕 500, 250 및 125 mg/kg의 경구투여는 OVX마우스에서 estrogen 결핍성 폐경기 관련 갱년기 장애(비만, 고지혈증, 간 지방병증 및 골다공증) 개선 효과를 투여 용량 의존적으로 나타내었다. 그러나 지백지황탕은 총 8종의 약제로 구성되어 있고, 각각 수많은 생리활성 물질을 함유하고 있어, 향후 생리활성을 나타내는 화학성분의 검색과 더불어 다양한 방면으로 기전적인 연구가 체계적으로 수행되어야 할 것으로 판단된다. Objectives: The purpose of this study was to evaluate the anti-climacterium effects of Jibaekjihwang-tang (JBJHT), especially on estrogenic, anti-obesity, hypolipidemic, hepatoprotective against fatty liver and anti-osteoporotic effects by Ovariectomy (OVX) mice. Methods: In order to evaluate anti-climacterium effects of JBJHT, we used bilateral OVX female ddY mice. In this study, six groups were used; sham control, OVX control, estradiol, JBJHT 500, 250 and 125 mg/kg treated groups. Since 28 days after OVX surgery, JBJHT extracts were orally treated, and 17β-estradiol 0.03 μg/head were subcutaneously injected for 84 days, once a day. And then, we observed anti-climacterium effects classified into five categories; estrogenic, anti-obesity, hypolipidemic, hepatoprotective against fatty liver and anti-osteoporotic effects. The results were compared with 17β-estradiol 0.03 μg/head/day subcutaneous treated OVX mice. Results: OVX control mice showed noticeable hypertrophic changes of adipocytes in abdominal fat pads, fatty liver, uterine atrophic changes, decreases of bone strength were also observed in OVX control. However, these estrogen-deficient climacterium symptoms were significantly and dose-dependently inhibited by JBJHT 500, 250 and 125 mg/kg treatment. Moreover, JBJHT 500 mg/kg showed comparable inhibitory effects as compared to those of estradiol 0.03 μg/head/day subcutaneous treatment. Conclusions: The results suggest that oral administration of JBJHT 500, 250 and 125 mg/kg has clear dose-dependent anti-climacterium effects in OVX mice.

글로벌리즘과 동아시아 불교미술 연구

이승혜 ( Seung Hye Lee ) 미술사와 시각문화학회 2014 미술사와 시각문화 Vol.13 No.-

The term ‘globalism’ or ‘global art history’ have been featured in titles of numerous books published, conferences held, or research projects conducted all over the globe in recent years. How has globalism affected the ways in which art historians perceive and rewrite art history`s largely Eurocentric framework? Could globalism, the product of the contemporary world, provide new perspectives on the product of distant past such as traditional East Asian Buddhist art without a ‘presentist’ bias? How do questions raised under the rubric of globalism differ from ones examined in traditional studies of East Asian Buddhist art? How might a concept like interregional or cross-cultural exchange take the place of the nation-state or the global as an analytical framework? This article maps out recent art historical discussions on globalism and examines their implications for studies of ancient and medieval East Asian Buddhist art. My discussion reveals that a global perspective has illuminated ‘hybrid’ art objects largely neglected in conventional art historical scholarship and rekindled interest in cross-cultural interaction that transcends geographical and political boundaries. Although many studies have thoroughly examined the issue of acculturation in East Asian Buddhist art, most of them trace movement of art objects, visual forms, or iconographical motifs through a linear perspective that more often than not flattens dynamics of cross-cultural exchange. However, recent studies propose to turn our attention from the interaction of visual forms to that of the ideas such as Buddhism and Catholicism or that of practices. The last section of my article proposes a new perspective, informed by recent scholarship on global art and cultural exchange, on the practice of enshrining relics and other sacred items within the inner recesses of Chinese Buddhist statues. It is often said that relics were enshrined in order to transform otherwise inert, material image of the Buddha into a living Buddha. However, examination of how the Gandharan practice of inserting a relic or jewel in a hole in the usnisa of a Buddhist image changed in medieval China reveals that conceptions of the iconic body changed in accordance with local conditions. I trace out larger trajectories of the two modes of placing objects inside Chinese images with a focus on the Seiryoji Buddha image, made in Taizhou in 985. I suggest that the combined deposit of relics inside the head and mock organs within the torso of the Seiryoji Buddha image was deeply rooted in the heightened awareness of corporeality?a cultural phenomenon that had appeared from the eighth century and that is clearly shown in the flesh-body icons of Chan masters.

[P3-210612] 코로나 19로 인한 복지원예사의 활동영역 변화와 스트레스 연구

이승혜(Seung Hye Lee),김영애(Young Ae Kim),임선미(Seon Mi Yim),제의숙(Eui Sook Je) 인간식물환경학회 2021 인간식물환경학회 학술대회 Vol.2021 No.춘계

마우스에서 2,4-Dinitrochlorobenzene을 이용한 아토피성 피부염 발현 관련 면역지표치 분석

이승혜(Seung Hye Lee),백성진(Seong Jin Baek),김형아(Hyoung Ah Kim),허용(Yong Heo) 한국독성학회 2006 Toxicological Research Vol.22 No.4

This study was undertaken to develop a reliable mice model demonstrating similar immunologic phenomena as human atopic dermatitis characterized with predominance of type-2 immune response. BALB/c mice and NC/Nga mice were sensitized twice with 100 ㎕ of 1% 2,4-dinitrochlorobenzene (DNCB) or vehicle (acetone : olive oil = 4 : 1 mixture) in a week and challenged twice with 100 ㎕ of 0.2% DNCB or the vehicle at the following week. Mice were sacrificed at 19 days following the second DNCB or vehicle challenge for NC/Nga mice and at 28 days following the second DNCB or vehicle challenge for BALB/c mice. Upregulation of plasma IgE, a hallmark of atopic dermatitis occurrence, was evident in the plasma obtained 4 day after the second DNCB challenge from BALB/c mice (approximately 4-fold) and NC/Nga mice (approximately 6-fold) treated with DNCB in comparison with that of the vehicle treated-control mice, and remain higher 3~4 week after the second challenge. Ratio of plasma IgG1 versus IgG2a concentration was significantly higher in the mice treated with DNCB than the control mice, which also implies the skewed type-2 reactivity in vivo. Ratio of interleukin-4 versus interferon gamma produced in the splenic T cell culture supernatants was approximately 3-fold higher in the both strains of mice treated with DNCB than their control mice, respectively. The DNCB-treated mice demonstrated atopic dermatitis-like skin legions characterized with erythma, scaling, and hemorrhage, which was not observed with the control mice. Scratching on face or dorsal area was significantly more frequent (approximately 25-fold) in the DNCB-treated mice than the control at next day of the second DNCB challenge, and scratching frequency remains higher (approximately 4-fold) in the mice treated with DNCB than the control at 14 day following the second DNCB challenge. Overall, the mice model developed through sensitization and challenge with DNCB may be useful for research on atopic dermatitis and development of treatment materials for atopic dermatitis.

폐경 후 여성에서의 대퇴부와 요추부 골밀도에 의한 골다공증 진단의 일치도

이승혜(Seung-Hye Lee),윤정은(Jeong Eun Yun),최윤선(Youn Seon Choi),양경선(Kyung-Sun Yang),엄현덕(Hyunduck Um),김선미(Seon Mee Kim),이준용(Joon Yong Lee),이승환(Seung Hwan Lee) 대한임상노인의학회 2013 대한임상노인의학회지 Vol.14 No.2

Background: Lumbar spine and total hip are widely used to measure bone mineral density (BMD) for diagnosis of osteoporosis. We want to evaluate relationship and concordance of the osteoporotic diagnosis between lumbar spine and total hip BMD in post-menopausal women. Methods: The BMD on both hips and lumbar spine of 100 healthy post-menopausal women were measured using dual-energy X-ray absorptiometry (DEXA). The BMDs of total hip and lumbar 1~4 were classified into normal (T-score>−1.0), osteopenia (−1.0≥T-score>−2.5), osteoporosis (T-score≤−2.5) using WHO definitions. Results: Based on L1~4 T-score there were 15 osteoporotic, 35 ostepenic, 50 normal persons, and based on total hip T-score there were 1 osteoporotic, 20 ostepenic, 79 normal persons. There was significant correlation between total hip and lumbar BMDs (r=0.695). For all age groups, lumbar BMDs are lower than hip BMDs and the gaps are severe in older group. The discordance rate was 43% for all cases, and this was 36% in their 50’s, 65% in 60’s, and 60% in 70’s with the highest rate in 60’s (P<0.05). The discordance rates of the normal, osteopenic and osteoporotic groups were 39, 60 and 0% respectively, with the highest rate in osteopenic group (P<0.05). Conclusion: The discordance rate between total hip and lumbar spine was as high as 43%, and was the highest in the osteopenic group in their 60’s. Therefore in post-menopausal women, the BMD of both sites should be checked together, but if not, the lumbar BMD should be checked first. 연구배경: 현재 골밀도 측정은 요추와 대퇴골 부위에서 가장 많이 시행되고 있는 상태로, 저자들은 만 50세 이상 폐경 후 여성에서 요추와 대퇴골의 골밀도를 측정하여 각 부위의 골밀도의 상관관계 및 골다공증 진단 일치도를 알아보고자 하였다. 방법: 건강한 폐경 후 여성 100명을 대상으로 대퇴부와 요추부의 골밀도를 DEXA 방법으로 측정하였다. 대퇴 총골밀도와 제 1~4요추 골밀도를 WHO 정의에 의하여 각각 정상(T-score>−1.0), 골감소증(−1.0≥T-score>−2.5), 골다공증(T-score≤−2.5)으로 분류하여 이들의 진단 일치도 및 상관관계를 측정하였다. 결과: 제 1~4요추 T-score를 기준으로 한 골다공증은 15명, 골감소는 35명, 정상은 50명이었으며, 대퇴 총골밀도를 기준으로 한 골다공증은 1명, 골감소는 20명, 정상은 79명이었다. 제1~4요추 평균 T-score와 총대퇴 T-score의 상관계수는 0.695로 서로 유의한 상관관계를 보였다. 골밀도는 전 연령대에서 요추부가 총대퇴부 보다 낮았으며, 그 차이는 연령이 증가할수록 심하였다. 제1~4요추 골밀도와 대퇴 총골밀도의 진단 불일치도는 100예중 43예에서 불일치를 보여 43.0%였다. 연령대별 불일치율은 50대, 60대, 70대가 각각 36%, 65%, 60%로 50대에 비해 60, 70대에서 높은 불일치율을 보였다(P<0.05). 대퇴 총골밀도를 기준으로 분류한 각 군에 따른 불일치율은 정상인군, 골감소군, 골다공증 군에서 각각 39%, 60%, 0%로 골감소 군에서 가장 높은 불일치율을 보였다(P<0.05). 결론: 요추와 대퇴 총골밀도의 진단 불일치율은 43.0%로 높았으며, 특히 60세 이상과 골감소 군에서 높았다. 따라서 폐경 후 여성에서 골밀도 측정시 가능하면 대퇴부와 요추부의 골밀도를 함께 측정해야 하며, 부득이하게 한 곳만의 골밀도를 측정한다면 요추부 골밀도를 우선적으로 측정하는 것이 좋을 것이라고 생각된다.