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이선영 ( Seon Yong Yi ),이상배 ( Sang Bae Lee ),류민혁 ( Min Hyuk Ryu ),이동진 ( Dong Jin Lee ) 대한소아알레르기호흡기학회 2003 소아알레르기 및 호흡기학회지 Vol.13 No.1
Pulmonary hamartoma is uncommon benign tumor-like malformation, which comprises ab-normal mixing of the normal components of the lung i.e., cartilage, fat, smooth muscle or respiratory epithelium. The majority occurs in fourth and fifth decades of life, b
자궁근종이 있는 한국여성에서 자기공명영상 유도하 고집적 초음파수술: 초기 임상경험
윤상욱 ( Sang Wook Yoon ),김경아 ( Kyoung Ah Kim ),황윤영 ( Youn Young Hwang ),이찬 ( Chan Lee ),차선희 ( Sun Hee Cha ),이선영 ( Sun Young Lee ),김용민 ( Yong Min Kim ),나영정 ( Young Jeong Na ),정상근 ( Sang Geun Jung ),김승조 ( 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.9
목적: 본 연구는 자궁근종에 대한 완전한 비침습적 치료인 자기공명영상 유도하 고집적 초음파수술 (MRgFUS)에 대한 안전성과 효과에 대해 알아보고자 시행되었다. 방법: 증상이 있는 29명의 자궁근종 환자 (평균나이 39.1±5.8세)에서 자기공명영상 유도하 고집적 초음파수술을 시행하였다. 환자들의 증상은 치료 당일, 치료 후 3개월, 6개월 추적검사 시 자궁근종 증상 설문지를 통해 기록하였다. 치료 당일과 추적검사 시 이상반응에 대해서도 기록하였다. 결과: 치료 후 3개월에 83% 그리고 6개월에 90%의 환자에서 증상의 호전이 있었다. 치료 중이나 치료 후 추적검사 시 환자에게 심각한 이상반응은 발생하지 않았다. 결론: 본 연구에서 자기공명영상 유도하 고집적 초음파수술은 증상이 있는 자궁근종환자에 있어 증상의 호전을 유도하는 안전하고도 효과적인 치료법으로 사료된다. Objective: The purpose of this report is to review the safety and short-term efficacy of non-invasive magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) on uterine myomas in Korean women. Methods: A total of 29 outpatient Korean women, whose mean age was 39.1±5.8 years, were treated using the MRgFUS system for their symptomatic uterine myomas. Patients` symptoms were recorded using a validated symptom-specific questionnaire on treatment day, and at follow-up visits, 3 and 6 months post treatment. Data on adverse events was recorded on each follow up period. Results: Symptom improvement was experienced by 83% of the patients at the three months follow-up, and 90% of the patients reported on improved quality of life by the six months follow-up. There were no serious adverse events during the treatments or the follow-up period. Conclusion: MRgFUS appears to be a safe and effective treatment for symptoms relief of uterine fibroids. Additional reports on longer follow up should verify long-term durability.
폴리타이포이드 경사 방식으로 접합 된 이종 세라믹간의 적층 수의 최적화 및 잔류응력 해석에 대한 연구
류새희,박종하,이선영,이재성,이재철,안성훈,김대근,채재홍,류도형,Ryu, Sae-Hee,Park, Jong-Ha,Lee, Sun-Yong,Lee, Jae-Sung,Lee, Jae-Chul,Ahn, Sung-Hoon,Kim, Dae-Keun,Chae, Jae-Hong,Riu, Do-Hyung 한국재료학회 2008 한국재료학회지 Vol.18 No.10
Crack-free joining of $Si_3N_4\;and\;Al_2O_3$ using 15 layers has been achieved by a unique approach introducing Sialon polytypoids as a functionally graded materials (FGMs) bonding layer. In the past, hot press sintering of multilayered FGMs with 20 layers of thickness $500{\mu}m$ each has been fabricated successfully. In this study, the number of layers for FGM was reduced to 15 layers from 20 layers for optimization. For fabrication, model was hot pressed at 38 MPa while heating up to $1700^{\circ}$, and it was cooled at $2^{\circ}$/min to minimize residual stress during sintering. Initially, FGM with 15 layers had cracks near 90 wt.% 12H / 10 wt.% $Al_2O_3$ and 90 wt.% 12H/10 wt.% $Si_3N_4$ layers. To solve this problem, FEM (finite element method) program based on the maximum tensile stress theory was applied to design optimized FGM layers of crack free joint. The sample is 3-dimensional cylindrical shape where this has been transformed to 2-dimensional axisymmetric mode. Based on the simulation, crack-free FGM sample was obtained by designing axial, hoop and radial stresses less than tensile strength values across all the layers of FGM. Therefore, we were able to predict and prevent the damage by calculating its thermal stress using its elastic modulus and coefficient of thermal expansion. Such analyses are especially useful for FGM samples where the residual stresses are very difficult to measure experimentally.