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이상학,문화식,Lee, Sang-Haak,Moon, Hwa-Sik 대한수면의학회 2003 수면·정신생리 Vol.10 No.1
Sleep apnea syndrome is a common clinical disorder characterized by intermittent cessation of airflow at nose and mouth during sleep. The clinical significance of this syndrome is that it is one of the most common causes of excessive daytime sleepiness. It can also cause neuropsychiatric, cardiovascular, and cerebrovascular complications. The standard for diagnosis of sleep apnea syndrome is nocturnal polysomnography. Because polysomnography is a time-consuming and expensive test, many efforts have been made to replace polysomnography with a simpler system of monitoring, but no method has yet been approved as a definitive investigation method. The goals of treatment for this syndrome are to eliminate excessive daytime sleepiness and to reduce the risk of possible cardiovascular complications. Continuous positive airway pressure is the most definite and widely accepted treatment for achieving these goals. Other treatments such as surgical treatment, oral appliances, and behavioral therapy may be useful for selected patients who are mildly affected.
전방경추융합술 후 발생한 역설상기도폐쇄 및 중추성 수면 무호흡
이상학 ( Sang Haak Lee ),최영미 ( Young Mee Choi ),박예리 ( Ye Ree Park ),강지호 ( Ji Ho Kang ),김영균 ( Young Kyoon Kim ),김관형 ( Kwan Hyoung Kim ),송정섭 ( Jeong Sup Song ),박성학 ( Sung Hak Park ),문화식 ( Hwa Sik Moon ) 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.58 No.3
We report a case of a 48-year-old man with a paradoxic upper airway obstruction and central sleep apnea that developed after an anterior cervical spinal fusion. Nine months before being admitted to this hospital, he was diagnosed with a herniated interver
Lewis 폐암 마우스 모델에서 Interleukin-12가 E-selectin 발현에 미치는 영향
이상학 ( Sang Haak Lee ),신윤 ( Yoon Shin ),윤형규 ( Hyoung Kyu Yoon ),이숙영 ( Sook Young Lee ),김석찬 ( Seok Chan Kim ),권순석 ( Soon Seog Kwon ),김영균 ( Young Kyoon Kim ),김관형 ( Kwan Hyoung Kim ),문화식 ( Hwa Sik Moon ) 대한결핵 및 호흡기학회 1999 Tuberculosis and Respiratory Diseases Vol.47 No.2
Pulmonary Artery Involvement As First Manifestation in Takayasu`s Arteritis
이상학 ( Sang Haak Lee ),송소향 ( So Hyang Song ),이숙영 ( Sook Young Lee ),김석찬 ( Seok Chan Kim ),최영미 ( Young Mi Choi ),서지원 ( Ji Won Suhr ),김치홍 ( Chi Hong Kim ),안종현 ( Joong Hyun Ahn ),김관형 ( Kwan Hyung Kim ),문화 대한내과학회 1999 대한내과학회 추계학술대회 Vol.57 No.-
증례 : 소화기 ; 등쪽 췌장무발생과 폐 낭종성병변을 동반한 위의 중복낭종
임성민 ( Sung Min Lim ),이혁 ( Hyeug Lee ),전은정 ( Eun Jung Jeon ),오정환 ( Jung Hwan Oh ),이상학 ( Sang Haak Lee ),최상욱 ( Sang Wook Choi ),이성 ( Seong Lee ) 대한내과학회 2009 대한내과학회지 Vol.76 No.2
위의 중복 낭종은 드문 선천성 기형으로, 본 증례에서는 특별한 증상 없이 건강 검진에서 발견된 폐의 낭종성 병변으로 내원하여 우연히 진단되었다. 폐의 낭종성 기형과 동반된 식도 중복이나 위의 중복은 보고되고 있으며, 환자의 경우도 연관된 선천성 기형 가능성을 배제할 수 없는 상태이다. 또한 특별한 증상은 없었지만, 검사에서 우연히 췌장의 배쪽 무발생이 발견되었으며, 우리나라에서 위의 중복낭종과 동반하여 보고된 증례는 없다. 이에 저자들은 문헌고찰과 함께 증례를 보고하는 바이다. Gastric duplication cysts and dorsal pancreatic agenesis are rare congenital anomalies, and little is known of the association between these two anomalies. A 17-year-old woman was admitted with a cystic lung mass detected as part of a health screening program. Chest computed tomography (CT) showed a cystic lung lesion in the right lower lobe and an incidental cystic abdominal mass. She had no specific symptoms or signs. Abdominal CT and endoscopic ultrasonography (EUS) revealed a 9×7×5.5-cm cystic mass and agenesis of the body and tail of the pancreas. The cyst was removed successfully using laparoscopic gastric wedge resection. Microscopically, the muscle coat of the cyst wall was fused with the muscle layer of the stomach. Therefore, the cystic mass was diagnosed as a gastric duplication cyst. We present a patient with a pulmonary cystic lesion associated with two congenital anomalies: a gastric duplication cyst and dorsal pancreatic agenesis. (Korean J Med 76:203-208, 2009)
김진우,이상학,Kim, Jin-Woo,Lee, Sang-Haak 대한기관식도과학회 2009 大韓氣管食道科學會誌 Vol.15 No.2
기관지내 평활근종은 기관지의 폐쇄정도에 따라 호흡곤란, 기침, 천명 등의 다양한 증세를 동반하며 그 증상이나 폐쇄정도가 경미할 경우 흉부 X-선 검사에서는 이상소견이 관찰되지 않을수도 있다. 따라서 폐렴이나 천식 등의 치료를 하다가 뒤늦게 발견되는 경우가 있는데 이 경우 반복적인 폐쇄성 폐렴과 폐농양, 기관지 확장증 등의 비가역적인 폐손상이 유발되며, 이는 전폐 절제술 등의 치료를 요하기도 한다. 따라서 무엇보다도 기관지내 평활근종의 치료 목표는, 증상에 따른 기관지내 병변의 의심과 기관지경에 의한 정확한 조기 진단과 보존적 수술, 내시경적 치료에 의해 비가역적인 폐손상을 방지하고 폐기능을 최대한 유지하는 것이다. 본 증례는 항생제 치료에 반응하지 않는 지속적인 폐렴으로 전원되어 온 환자에서 기관지경시행 후 기관지내 평활근종을 진단한 경우로, 이와 같은 경우 기관지내 병변의 가능성에 대해 반드시 고려하고 조기에 기관지경을 시행하여 정확한 진단을 하는 것이 무엇보다 중요하다고 하겠다. A 44 year-old nonsmoker female presented to our hospital with persistent cough with sputum for three months. She had been diagnosed as pneumonia and treated with antibiotics in a local hospital but was transferred to our hospital because of no symptomatic improvement. We performed flexible bronchoscopy and found an ovoid and smooth surfaced mass obstructing the bronchus of right middle lobe. The biopsy specimen revealed a benign tumor composed of spindle cells without dysplasia consistent with leiomyoma. There was no evidence of leiomyoma in uterus. The right middle lobectomy and bronchoplasty were performed and the patient was healthy twelve months later. Primary endobronchial leiomyoma is a rare benign tumor of the lung. Herein we report a case of primary endobronchial leiomyoma diagnosed during treatment of pneumonia.